REFERENCES
- Lee V H. Membrane transporters. Eur J Pharm Sci 2000; 11(Suppl. 2)S41–50, [INFOTRIEVE], [CSA]
- Bolger M B, Haworth I S, Yeung A K, et al. Structure, function, and molecular modeling approaches to the study of the intestinal dipeptide transporter PepT1. J Pharm Sci 1998; 87: 1286–1291, [INFOTRIEVE], [CSA], [CROSSREF]
- Han F, Le G W, Shi Y H. [Molecular characteristics and tissue distribution of peptide transporters]. Sheng Li Ke Xue Jin Zhan 2003; 34: 222–226, [INFOTRIEVE], [CSA]
- Kim D K, Kanai Y, Chairoungdua A, et al. Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem 2001; 276: 17221–17228, [INFOTRIEVE], [CSA], [CROSSREF]
- Lee W, Kim R B. Transporters and renal drug elimination. Annu Rev Pharmacol Toxicol 2004; 44: 137–166, [INFOTRIEVE], [CSA], [CROSSREF]
- Tamai I, Tsuji A. Transporter-mediated permeation of drugs across the blood-brain barrier. J Pharm Sci 2000; 89: 1371–1388, [INFOTRIEVE], [CSA], [CROSSREF]
- Tsuji A, Tamai I. Carrier-mediated intestinal transport of drugs. Pharm Res 1996; 13: 963–977, [INFOTRIEVE], [CSA], [CROSSREF]
- Anand B S, Katragadda S, Nashed Y E, Mitra A K. Amino acid prodrugs of acyclovir as possible antiviral agents against ocular HSV-1 infections: interactions with the neutral and cationic amino acid transporter on the corneal epithelium. Curr Eye Res 2004; 29: 153–166, [INFOTRIEVE], [CSA], [CROSSREF]
- Anand B S, Mitra A K. Mechanism of corneal permeation of L-valyl ester of acyclovir: targeting the oligopeptide transporter on the rabbit cornea. Pharm Res 2002; 19: 1194–1202, [INFOTRIEVE], [CSA], [CROSSREF]
- Bildin V N, Iserovich P, Fischbarg J, Reinach P S. Differential expression of Na:K:2Cl cotransporter, glucose transporter 1, and aquaporin 1 in freshly isolated and cultured bovine corneal tissues. Exp Biol Med (Maywood) 2001; 226: 919–926, [CSA]
- Chen C H, Chen S C. Lactate transport and glycolytic activity in the freshly isolated rabbit cornea. Arch Biochem Biophys 1990; 276: 70–76, [INFOTRIEVE], [CSA], [CROSSREF]
- Giasson C, Bonanno J A. Facilitated transport of lactate by rabbit corneal endothelium. Exp Eye Res 1994; 59: 73–81, [INFOTRIEVE], [CSA], [CROSSREF]
- Ishida K, Yamashita H, Katagiri H, Oka Y. Regulation of glucose transporter 1 (GLUT1) gene expression by epidermal growth factor in bovine corneal endothelial cells. Jpn J Ophthalmol 1995; 39: 225–232, [INFOTRIEVE], [CSA]
- Jain-Vakkalagadda B, Dey S, Pal D, Mitra A K. Identification and functional characterization of a Na+-independent large neutral amino acid transporter, LAT1, in human and rabbit cornea. Invest Ophthalmol Vis Sci 2003; 44: 2919–2927, [INFOTRIEVE], [CSA], [CROSSREF]
- Majumdar S, Gunda S, Mitra A. Functional expression of a sodium dependent nucleoside transporter on rabbit cornea: Role in corneal permeation of acyclovir and idoxuridine. Curr Eye Res 2003; 26: 175–183, [INFOTRIEVE], [CSA], [CROSSREF]
- Majumdar S, Tirucherai G S, Pal D, Mitra A K. Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea. AAPS PharmSci 2003; 5: E15, [INFOTRIEVE], [CSA], [CROSSREF]
- Ban Y, Rizzolo L J. Regulation of glucose transporters during development of the retinal pigment epithelium. Brain Res Dev Brain Res 2000; 121: 89–95, [INFOTRIEVE], [CSA], [CROSSREF]
- Gu S, Roderick H L, Camacho P, Jiang J X. Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport. J Biol Chem 2001; 276: 24137–24144, [INFOTRIEVE], [CSA], [CROSSREF]
- Harada T, Harada C, Watanabe M, et al. Functions of the two glutamate transporters GLAST and GLT-1 in the retina. Proc Natl Acad Sci U S A 1998; 95: 4663–4666, [INFOTRIEVE], [CSA], [CROSSREF]
- Hosoya K, Horibe Y, Kim K J, Lee V H. Na(+)-dependent L-arginine transport in the pigmented rabbit conjunctiva. Exp Eye Res 1997; 65: 547–553, [INFOTRIEVE], [CSA], [CROSSREF]
- Hosoya K, Horibe Y, Kim K J, Lee V H. Nucleoside transport mechanisms in the pigmented rabbit conjunctiva. Invest Ophthalmol Vis Sci 1998; 39: 372–377, [INFOTRIEVE], [CSA]
- Kompella U B, Kim K J, Shiue M H, Lee V H. Possible existence of Na(+)-coupled amino acid transport in the pigmented rabbit conjunctiva. Life Sci 1995; 57: 1427–1431, [INFOTRIEVE], [CSA], [CROSSREF]
- Pow D V. Amino acids and their transporters in the retina. Neurochem Int 2001; 38: 463–484, [INFOTRIEVE], [CSA], [CROSSREF]
- Rajan P D, Kekuda R, Chancy C D, et al. Expression of the extraneuronal monoamine transporter in RPE and neural retina. Curr Eye Res 2000; 20: 195–204, [INFOTRIEVE], [CSA], [CROSSREF]
- Williams E F, Ezeonu I, Dutt K. Nucleoside transport sites in a cultured human retinal cell line established by SV-40 T antigen gene. Curr Eye Res 1994; 13: 109–118, [INFOTRIEVE], [CSA]
- Merrill A H, Jr., Lambeth J D, Edmondson D E, McCormick D B. Formation and mode of action of flavoproteins. Annu Rev Nutr 1981; 1: 281–317, [INFOTRIEVE], [CSA], [CROSSREF]
- Cooperman J M, Lopez R. Riboflavin. Handbook of Vitamins: Nutritional, Biochemical and Clinical Aspects, L J Machlin. Marcel Dekker, New York 1984; 299–327
- Huang S N, Swaan P W. Involvement of a receptor-mediated component in cellular translocation of riboflavin. J Pharmacol Exp Ther 2000; 294: 117–125, [INFOTRIEVE], [CSA]
- Kumar C K, Yanagawa N, Ortiz A, Said H M. Mechanism and regulation of riboflavin uptake by human renal proximal tubule epithelial cell line HK-2. Am J Physiol 1998; 274: F104–110, [INFOTRIEVE], [CSA]
- Said H M, Ma T Y. Mechanism of riboflavine uptake by Caco-2 human intestinal epithelial cells. Am J Physiol 1994; 266: G15–21, [INFOTRIEVE], [CSA]
- Said H M, Ortiz A, Ma T Y, McCloud E. Riboflavin uptake by the human-derived liver cells Hep G2: mechanism and regulation. J Cell Physiol 1998; 176: 588–594, [INFOTRIEVE], [CSA], [CROSSREF]
- Said H M, Ortiz A, Moyer M P, Yanagawa N. Riboflavin uptake by human-derived colonic epithelial NCM460 cells. Am J Physiol Cell Physiol 2000; 278: C270–276, [INFOTRIEVE], [CSA]
- Kansara V, Pal D, Jain R, Mitra A K. Identification and functional characterization of riboflavin transporter in human-derived retinoblastoma cell line (Y-79): mechanisms of cellular uptake and translocation. J Ocul Pharmacol Ther 2005; 21: 275–287, [INFOTRIEVE], [CSA], [CROSSREF]
- Said H M, Wang S, Ma T Y. Mechanism of riboflavin uptake by cultured human retinal pigment epithelial ARPE-19 cells: possible regulation by an intracellular Ca2+-calmodulin-mediated pathway. J Physiol 2005; 566: 369–377, [INFOTRIEVE], [CSA], [CROSSREF]
- Pepose J S, Ubels J L. The cornea. Adler's Physiology of the Eye, 9th ed., W M Hart. Mosby, St. Louis 1992; 29–70
- Klyce S D, Crosson C E. Transport processes across the rabbit corneal epithelium: a review. Curr Eye Res 1985; 4: 323–331, [INFOTRIEVE], [CSA]
- Bellomio S. [Clinical contribution on riboflavin deficiency of the eye]. Boll Ocul 1955; 34: 157–170, [INFOTRIEVE], [CSA]
- Irinoda K, Sato S. Contribution to the ocular manifestation of riboflavin deficiency. Tohoku J Exp Med 1954; 61: 93–104, [INFOTRIEVE], [CSA]
- Stern J J. The ocular manifestations of riboflavin deficiency. Am J Ophthalmol 1950; 33: 1127–1136, [INFOTRIEVE], [CSA]
- Wiesinger H, Kaunitz H, Slanetz C A. [Corneal changes in riboflavin-deficient rats]. Ophthalmologica 1955; 129: 389–395, [INFOTRIEVE], [CSA]
- Takami Y, Gong H, Amemiya T. Riboflavin deficiency induces ocular surface damage. Ophthalmic Res 2004; 36: 156–165, [INFOTRIEVE], [CSA], [CROSSREF]
- Cumming R G, Mitchell P, Smith W. Diet and cataract: the Blue Mountains Eye Study. Ophthalmology 2000; 107: 450–456, [INFOTRIEVE], [CSA], [CROSSREF]
- Miyamoto Y, Sancar A. Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals. Proc Natl Acad Sci U S A 1998; 95: 6097–6102, [INFOTRIEVE], [CSA], [CROSSREF]
- Horwitz J, Dovrat A, Straatsma B R, Revilla P J, Lightfoot D O. Glutathione reductase in human lens epithelium: FAD-induced in vitro activation. Curr Eye Res 1987; 6: 1249–1256, [INFOTRIEVE], [CSA]
- Skalka H W, Prchal J T. Cataracts and riboflavin deficiency. Am J Clin Nutr 1981; 34: 861–863, [INFOTRIEVE], [CSA]
- Batey D W, Eckhert C D. Analysis of flavins in ocular tissues of the rabbit. Invest Ophthalmol Vis Sci 1991; 32: 1981–1985, [INFOTRIEVE], [CSA]
- Hirano H, Hamajima S, Horiuchi S, et al. Effects of B2-deficiency on lipoperoxide and its scavenging system in the rat lens. Int J Vitam Nutr Res 1983; 53: 377–382, [INFOTRIEVE], [CSA]
- Horwitt M K, Sebrell W H, Harris R S. The Vitamins. Academic Press, New York 1972
- Dutta P, Rivlin R S, Pinto J. Enhanced depletion of lens reduced glutathione Adriamycin in riboflavin-deficient rats. Biochem Pharmacol 1990; 40: 1111–1115, [INFOTRIEVE], [CSA], [CROSSREF]
- Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 2003; 135: 620–627, [INFOTRIEVE], [CSA], [CROSSREF]
- Balant L P, Doelker E, Buri P. Prodrugs for the improvement of drug absorption via different routes of administration. Eur J Drug Metab Pharmacokinet 1990; 15: 143–153, [INFOTRIEVE], [CSA]
- Dey S, Mitra A K. Transporters and receptors in ocular drug delivery: opportunities and challenges. Expert Opin Drug Deliv 2005; 2: 201–204, [INFOTRIEVE], [CSA], [CROSSREF]
- Majumdar S, Nashed Y E, Patel K, et al. Dipeptide monoester ganciclovir prodrugs for treating HSV-1-induced corneal epithelial and stromal keratitis: in vitro and in vivo evaluations. J Ocul Pharmacol Ther 2005; 21: 463–474, [INFOTRIEVE], [CSA], [CROSSREF]
- Masteikova R, Chalupova Z, Savickiene N. [Biological availability of ophthalmic drugs. 1. Increasing drug permeability in the cornea]. Ceska Slov Farm 2004; 53: 73–79, [INFOTRIEVE], [CSA]
- Sasaki H, Yamamura K, Mukai T, et al. Enhancement of ocular drug penetration. Crit Rev Ther Drug Carrier Syst 1999; 16: 85–146, [INFOTRIEVE], [CSA]
- Dey S, Patel J, Anand B S, et al. Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines. Invest Ophthalmol Vis Sci 2003; 44: 2909–2918, [INFOTRIEVE], [CSA], [CROSSREF]
- Bradford M M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248–254, [INFOTRIEVE], [CSA], [CROSSREF]
- Tak R V, Pal D, Gao H, et al. Transport of acyclovir ester prodrugs through rabbit cornea and SIRC-rabbit corneal epithelial cell line. J Pharm Sci 2001; 90: 1505–1515, [INFOTRIEVE], [CSA], [CROSSREF]
- Huang S N, Swaan P W. Riboflavin uptake in human trophoblast-derived BeWo cell monolayers: cellular translocation and regulatory mechanisms. J Pharmacol Exp Ther 2001; 298: 264–271, [INFOTRIEVE], [CSA]
- Zempleni J, Mock D M. Proliferation of peripheral blood mononuclear cells increases riboflavin influx. Proc Soc Exp Biol Med 2000; 225: 72–79, [INFOTRIEVE], [CSA], [CROSSREF]
- Hediger M A, Kanai Y, You G, Nussberger S. Mammalian ion-coupled solute transporters. J Physiol 1995; 482: 7S–17S, [INFOTRIEVE], [CSA]
- Sundaram U. Regulation of intestinal vitamin B(2) absorption. Focus on “Riboflavin uptake by human-derived colonic epithelial NCM460 cells”. Am J Physiol Cell Physiol 2000; 278: C268–269, [INFOTRIEVE], [CSA]
- Griffith J, Sansom C. The Transporter Factsbook. Academic Press, San Diego 1998
- Said H M. Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins. Annu Rev Physiol 2004; 66: 419–446, [INFOTRIEVE], [CSA], [CROSSREF]