Pulmonary hypertension is associated with impaired exercise performance in patients with systemic sclerosis

Reference

• Le Roy EC. Systemic sclerosis (scleroderma). In: Wyngaarden JB, Smith LH Jr, eds. Cecil textbook of medicine. Philadel-phia: Saunders, 1988:2:2018–33.
   Google Scholar
• Lee P, Langevitz P, Busklia D. Mortality in systemic sclerosis (scleroderma). Arthritis Rheum 1980;23:581–90.
   PubMedGoogle Scholar
• lingerer RG, Tashkin DP, Furst D, Clemence PJ, Gong H Jr, Bein M, et al. Prevalence and clinical correlates of pulmonary arterial hypertension in progressive systemic sclerosis. Am J Med 1983;75:65–74.
   Google Scholar
• Owens G, Fino G, Herbert D, Steen V, Medsger T, Diamond H. Pulmonary function in scleroderma. Arthritis Rheum 1977;20:1071–9.
   PubMedGoogle Scholar
• Morelli S, Sgreccia A, Ferrante L, Barbieri C, Bernardo ML, Perrone C, et al. Relationships between electrocardiographic and echocardiographic findings in systemic sclerosis (sclero-derma). Int J Cardiol 1996;57:151–60.
   PubMed Web of Science ®Google Scholar
• Smith J, Clements P, Levisman J, Furst D, Ross M. Ecocardiographic features of progressive systemic sclerosis (PSS); correlation with hemodynamics and post-mortem studies. Am J Med 1979;66:391–8.
   Google Scholar
• Follansbee W, Curtiss E, Medsger T, Steen V, Uretsky B, Owens G, et al. Physiologic abnormalities of cardiac function in progressive systemic sclerosis with diffuse scleroderma. N Engl J Med 1984;310:142–8.
   PubMed Web of Science ®Google Scholar
• Kazzam, Caidhal K, Hallgren R, Johansson C, Waldenstrom A. Mitral regurgitation and diastolic flow profile in systemic sclerosis. Int J Cardiol 1990;29:367–73.
   Google Scholar
• Greenwald GI, Tashkin DP, Gong H, Simmons M, Duann S, Furst DE, et al. Longitudinal changes in lung function and respiratory symptoms in progressive systemic sclerosis. A prospective study. Am J Med 1987;83:83–91.
   PubMedGoogle Scholar
• Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1981; 23:581–90.
   Google Scholar
• Clements PJ, Medsger TA Jr. Skin involvement. In: Clements PJ, Furst DE, eds. Systemic Sclerosis. Baltimore: Williams and Wilkins, 1996:389–408.
   Google Scholar
• Henry WL, DeMaria A, Gramiak R, King DL, Kisslo JA, Popp RL, et al. Report of the American Society of Echocardiography Committee on nomenclature and standards in two-dimensional echocardiography. Circulation 1980; 62:212–7.
   PubMed Web of Science ®Google Scholar
• Currie PJ, Seward JB, Chan KL, Fyfe DA, Hagler DJ, Mair DD, et al. Continuous-wave Doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patients. J Am Coll Cardiol 1985;6:750–6.
   PubMed Web of Science ®Google Scholar
• Ogilvie CM, Forster RE, Blakemore WS, Morton JW. A standardized breath holding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide. J Clin Invest 1957;36:1–17.
   PubMed Web of Science ®Google Scholar
• Zavala DC, ed. Manual on exercise testing: a training handbook. Iowa city: Press of the University of Iowa, 1985.
   Google Scholar
• Wasserman K. Determinants and detection of anaerobic threshold and consequences of exercise above it. Circulation 1987;76 ;VI:29–39.
   Google Scholar
• Wasserman K, Hansen JE, Sue DY, Whipp BJ, eds. Principles of exercise testing and interpretation. Philadelphia: Lea & Febiger, 1986.
   Google Scholar
• Clements PJ, Lachenbruch PA, Ng SC, Simmons M, Sterz MG, Furst DE. Skin score: a semiquantitative measure of cutaneous involvement which improves prediction of prog-nosis in systemic sclerosis. Arthritis Rheum 1990;33:1256–63.
   PubMed Web of Science ®Google Scholar
• Godfrey S, Blueston R, Higgs BE. Lung function and the response to exercise in systemic sclerosis. Thorax 1969;24:427–33.
   Google Scholar
• Blom-Billow B, Jonson B, Baur K. Factors limiting exercise performance in progressive systemic sclerosis. Semin Arthritis Rheum 1983;13:174–81.
   PubMedGoogle Scholar
• Schwaiblmair M, Behr J, Fruhmann G. Cardiorespiratory responses to incremental exercise in patients with systemic sclerosis. Chest 1996;110:1520–5.
   Google Scholar
• Sudduth CD, Strange C, Cook WR, Millers KS, Bowmann M, Conlop NA, et al. Failure of the circulatory system limits exercise performance in patients with systemic sclerosis. Am J Med 1993;95:413–8.
   PubMed Web of Science ®Google Scholar
• Norton WL, Nardo JM. Vascular disease in progressive systemic sclerosis (scleroderma). Ann Intern Med 1970; 73:317–24.
   PubMed Web of Science ®Google Scholar
• Al-Sabbagh MR, Steen VD, Zee BC, Nalesnik M, Trostle DC, Bedetti CD, et al. Pulmonary arterial histology and morphometry in systemic sclerosis: a case control autopsy study. J Rheumatol 1989;16:1038–42.
   Google Scholar
• D'Angelo WA, Fries JF, Masi AT, Shulman LE. Pathologic observations in systemic sclerosis (scleroderma). Am J Med 1969;46:428–40.
   PubMed Web of Science ®Google Scholar
• Dujié ‘Z, Eterovie D, Tocilj J, Andjelinovié D. Increase of pulmonary diffusing capacity in systemic sclerosis. Br J Rheumatol 1994;33:437–41.
   Google Scholar
• Baker BJ, Wilen MM, Boyd CM, Dinh H, Franciosa JA. Relation of right ventricular ejection fraction to exercise capacity in chronic left ventricular failure. Am J Cardiol 1984;54:596–9.
   Google Scholar
• Franciosa JA, Baker BJ, Seth L. Pulmonary versus systemic hemodinamics in determining exercise capacity of patients with chronic left ventricular failure. Am Heart J 1985;110: 807–13.
   Google Scholar
• Raeside DA, Chalmers G, Clelland J, Madhock, Peacock AJ. Pulmonary artery pressure variation in patients with con-nective tissue disease: 24 hour ambulatory pulmonary artery pressure monitoring. Thorax 1998;53: 857–62.
   Google Scholar
• Sullivan MJ, Knight JD, Higginbotham MB, Cobb FR. Relation between central and peripheral hemodynamics during exercise in patients with chronic heart failure. Muscle blood flow is reduced with manteinance of arterial perfusion pressure. Circulation 1989;80:769–81.
   Google Scholar
• Wilson JR, Martin JL, Schwartz DE, Ferraro N. Exercise intolerance in patients with cronic heart failure: role of impaired nutritive flow to skeletal muscle. Circulation 1984;69:1079–87.
   PubMed Web of Science ®Google Scholar
• Wilson JR, Martin JL, Ferraro N. Impaired skeletal muscle nutritive flow during exercise in patients with congestive heart failure: role of cardiac pump dysfunction as determined by the effect of dobutamine. Am J Cardiol 1984;53:1308–15.
   Google Scholar
• Kahn A, Nitenberg A, Foult JM, Amor B, Menkès CJ, Devaux JY, et al. Decreased coronary reserve in primary scleroderma myocardial disease. Arthritis Rheum 1985; 28:637–46.
   Google Scholar
• Escudero J, McDevitt E. The electrocardiogram in sclero-derma: analysis of 60 cases and review of the literature. Am Heart J 1958;56:846–55.
   PubMedGoogle Scholar
• Ringel RA, Brick JE, BrickJF, Gutman L, Riggs JE. Muscle involvement in the scleroderma syndromes. Arch Intern Med 1990;150:2550–2.
   PubMedGoogle Scholar
• Yamane K, Kashiwagi H, Suzuki N, Miyauchi T, Yanagisawa M, Goto K, et al. Elevated plasma levels of endothelin-1 in systemic sclerosis. Arthritis Rheum 1991;34:243–4.
   PubMedGoogle Scholar
• Kahaleh MB. Endothelin and endothelial-dependent vaso-constrictor in scleroderma. Arthritis Rheum 1991;34:978–83.
   PubMed Web of Science ®Google Scholar
• Morelli S, Ferri C, Polettini E, Bellini C, Gualdi GF, Pittoni V, et al. Plasma endothelin-1 levels, pulmonary hypertension and lung fibrosis in patients with systemic sclerosis. Am J Med 1995;99:55–60.
   PubMedGoogle Scholar
• Banci M, Rinaldi E, Ierardi M, Tiberio NS, Boccabella GL, Barbieri C, et al. 99mTc SESTAMIBI scintigraphic evaluation of skeletal muscle disease in patients with systemic sclerosis: diagnostic reliability and comparison with cardiac function and perfusion. Angiology 1998;49:641–7.
   PubMedGoogle Scholar
• Mancini DM, Nazzaro D, Georgopoulos L, Wagner N, Mullen JL, Wilson JR. Skeletal muscle atrophy contributes to exercise intolerance in heart failure. J Am Coll Cardiol 1991;17 Suppl A, Abstract:88A.
   Google Scholar