The relationship between cadmium and cognition in the elderly: a systematic review

References

• Alzheimer's Association 2016. 2016 Alzheimer’s disease facts and figures. Alzheimers Dement. 12(4):459–509.
   PubMedGoogle Scholar
• Ahn SC, Chang JY, Lee JS, Yu HY, Jung AR, Kim JY, Choi JW, et al. 2017. Exposure factors of cadmium for residents in an abandoned metal mine area in Korea. Environ Geochem Health. 39(5):1059–1070.
   PubMed Web of Science ®Google Scholar
• Bakulski KM, Seo YA, Hickman RC, Brandt D, Vadari HS, Hu H, Park SK. 2020. Heavy metals exposure and alzheimer’s disease and related dementias. JAD. 76(4):1215–1242.
   Web of Science ®Google Scholar
• Bimonte VM, Besharat ZM, Antonioni A, Cella V, Lenzi A, Ferretti E, Migliaccio S. 2021. The endocrine disruptor cadmium: a new player in the pathophysiology of metabolic diseases. J Endocrinol Invest. 44(7):1363–1377.
   PubMed Web of Science ®Google Scholar
• Branca JJV, Morucci G, Pacini A. 2018. Cadmium-induced neurotoxicity: still much ado. Neural Regen Res. 13(11):1879–1882.
   PubMed Web of Science ®Google Scholar
• Briffa J, Sinagra E, Blundell R. 2020. Heavy metal pollution in the environment and their toxicological effects on humans. Heliyon. 6(9):e04691.
   PubMed Web of Science ®Google Scholar
• Campbell NL, Unverzagt F, LaMantia MA, Khan BA, Boustani MA. 2013. Risk factors for the progression of mild cognitive impairment to dementia. Clin Geriatr Med. 29(4):873–893.
   PubMed Web of Science ®Google Scholar
• Chin-Chan M, Navarro-Yepes J, Quintanilla-Vega B. 2015. Environmental pollutants as risk factors for neurodegenerative disorders: alzheimer and Parkinson diseases. Front Cell Neurosci. 9:124.
   PubMed Web of Science ®Google Scholar
• Emsley CL, Gao S, Li Y, Liang C, Ji R, Hall KS, Cao J, et al. 2000. Trace element levels in drinking water and cognitive function among elderly Chinese. Am J Epidemiol. 151(9):913–920.
   PubMed Web of Science ®Google Scholar
• Eshkoor SA, Hamid TA, Mun CY, Ng CK. 2015. Mild cognitive impairment and its management in older people. Clin Interv Aging. 10:687–693.
   PubMed Web of Science ®Google Scholar
• Gao S, Jin Y, Unverzagt FW, Ma F, Hall KS, Murrell JR, Cheng Y, et al. 2008. Trace element levels and cognitive function in rural elderly Chinese. J Gerontol A Biol Sci Med Sci. 63(6):635–641.
   PubMed Web of Science ®Google Scholar
• Garner R, Levallois P. 2016. Cadmium levels and sources of exposure among Canadian adults. Health Rep. 27(2):10–18.
   PubMed Web of Science ®Google Scholar
• Genchi G, Sinicropi MS, Lauria G, Carocci A, Catalano A. 2020. The effects of cadmium toxicity. Int J Environ Res Public Health. 17(11):3782.
   PubMed Web of Science ®Google Scholar
• Ghazali AR, Kamarulzaman F, Normah CD, Ahmad M, Ghazali SE, Ibrahim N, Said Z, et al. 2013. Levels of Metallic Elements and Their Potential Relationships to Cognitive Function among Elderly from Federal Land Development Authority (FELDA) Settlement in Selangor Malaysia. Biol Trace Elem Res. 153(1-3):16–21.
   PubMed Web of Science ®Google Scholar
• Goyer RA. 1997. Toxic and essential metal interactions. Annu Rev Nutr. 17:37–50.
   PubMed Web of Science ®Google Scholar
• Gustin K, Tofail F, Vahter M, Kippler M. 2018. Cadmium exposure and cognitive abilities and behavior at 10 years of age: a prospective cohort study. Environ Int. 113:259–268.
   PubMed Web of Science ®Google Scholar
• Halder S, Kar R, Galav V, Mehta AK, Bhattacharya SK, Mediratta PK, Banerjee BD. 2016. Cadmium exposure during lactation causes learning and memory-impairment in F1 generation mice: amelioration by quercetin. Drug Chem Toxicol. 39(3):272–278.
   PubMed Web of Science ®Google Scholar
• Hang L, Liqin S, Xi C, Sisi W, Yibin C, Shaobin L, Liang D, et al. 2021. Higher blood cadmium level is associated with greater cognitive decline in rural Chinese adults aged 65 or older. Sci Total Environ. 756:144072.
   PubMed Web of Science ®Google Scholar
• Hongyu L, Zhihui W, Zhen F, Mingming Y, Nanjin W, Hongyan W, Ping Y. 2018. Associations between blood cadmium levels and cognitive function in a cross-sectional study of US adults aged 60 years or older. BMJ open. 8(4):e020533.
   PubMed Web of Science ®Google Scholar
• Huang G, Ren G. 2022. Interaction between ω-6 fatty acids intake and blood cadmium on the risk of low cognitive performance in older adults from National Health and Nutrition Examination Survey (NHANES) 2011-2014. BMC Geriatr. 22(1):292.
   PubMed Web of Science ®Google Scholar
• Huat TJ, Camats-Perna J, Newcombe EA, Valmas N, Kitazawa M, Medeiros R. 2019. Metal toxicity links to alzheimer’s disease and neuroinflammation. J Mol Biol. 431(9):1843–1868.
   PubMed Web of Science ®Google Scholar
• Iqbal G, Zada W, Mannan A, Ahmed T. 2018. Elevated heavy metals levels in cognitively impaired patients from Pakistan. Environ Toxicol Pharmacol. 60:100–109.
   PubMed Web of Science ®Google Scholar
• Kang MY, Cho SH, Lim YH, Seo JC, Hong YC. 2013. Effects of environmental cadmium exposure on liver function in adults. Occup Environ Med. 70(4):268–273.
   PubMed Web of Science ®Google Scholar
• Karri V, Schuhmacher M, Kumar V. 2016. Heavy metals (Pb, Cd, As and MeHg) as risk factors for cognitive dysfunction: a general review of metal mixture mechanism in brain. Environ Toxicol Pharmacol. 48:203–213.
   PubMed Web of Science ®Google Scholar
• Kim H, Lee S, Ku BD, Ham SG, Park WS. 2019. Associated factors for cognitive impairment in the rural highly elderly. Brain Behav. 9(5):e01203.
   PubMed Web of Science ®Google Scholar
• Kumar S, Sharma A. 2019. Cadmium toxicity: effects on human reproduction and fertility. Rev Environ Health. 34(4):327–338.
   PubMed Web of Science ®Google Scholar
• Lafuente A. 2013. The hypothalamic-pituitary-gonadal axis is target of cadmium toxicity. An update of recent studies and potential therapeutic approaches. Food Chem Toxicol. 59:395–404.
   PubMed Web of Science ®Google Scholar
• Lin L, Chu H. 2018. Quantifying publication bias in meta-analysis. Biometrics. 74(3):785–794.
   PubMed Web of Science ®Google Scholar
• Lindenberger U. 2014. Human cognitive aging: corriger la fortune? Science. 346(6209):572–578.
   PubMed Web of Science ®Google Scholar
• Liu SI, Prince M, Chiu MJ, Chen TF, Sun YW, Yip PK. 2005. Validity and reliability of a Taiwan Chinese version of the community screening instrument for dementia. Am J Geriatr Psychiatry. 13(7):581–588.
   PubMed Web of Science ®Google Scholar
• Liu Z, Cai L, Liu Y, Chen W, Wang Q. 2019. Association between prenatal cadmium exposure and cognitive development of offspring: a systematic review. Environ Pollut. 254(Pt B):113081.
   PubMed Web of Science ®Google Scholar
• Marshall TM, Dardia GP, Colvin KL, Nevin R, Macrellis J. 2019. Neurotoxicity associated with traumatic brain injury, blast, chemical, heavy metal and quinoline drug exposure. Altern Ther Health Med. 25(1):28–34.
   PubMed Web of Science ®Google Scholar
• Méndez-Armenta M, Ríos C. 2007. Cadmium neurotoxicity. Environ Toxicol Pharmacol. 23(3):350–358.
   PubMed Web of Science ®Google Scholar
• Mezynska M, Brzóska MM. 2018. Environmental exposure to cadmium-a risk for health of the general population in industrialized countries and preventive strategies. Environ Sci Pollut Res Int. 25(4):3211–3232.
   PubMed Web of Science ®Google Scholar
• Min JY, Min KB. 2016. Blood cadmium levels and Alzheimer’s disease mortality risk in older US adults. Environ Health. 15(1):69.
   PubMed Web of Science ®Google Scholar
• Moye J, Marson DC, Edelstein B. 2013. Assessment of capacity in an aging society. Am Psychol. 68(3):158–171.
   PubMed Web of Science ®Google Scholar
• Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, Cummings JL, Chertkow H. 2005. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 53(4):695–699.
   PubMed Web of Science ®Google Scholar
• Nordberg M, Nordberg GF. 2022. Metallothionein and cadmium toxicology-historical review and commentary. Biomolecules. 12(3):360.
   PubMed Web of Science ®Google Scholar
• Oliveira AS, Costa EAC, Pereira EC, Freitas MAS, Freire BM, Batista BL, Luz MS, Olympio KPK. 2021. The applicability of fingernail lead and cadmium levels as subchronic exposure biomarkers for preschool children. Sci Total Environ. 758:143583.
   PubMed Web of Science ®Google Scholar
• Olsson IM, Eriksson J, Oborn I, Skerfving S, Oskarsson A. 2005. Cadmium in food production systems: a health risk for sensitive population groups. Ambio. 34(4-5):344–351.
   PubMed Web of Science ®Google Scholar
• Peng Q, Bakulski KM, Nan B, Park SK. 2017. Cadmium and Alzheimer’s disease mortality in U.S. adults: updated evidence with a urinary biomarker and extended follow-up time. Environ Res. 157:44–51.
   PubMed Web of Science ®Google Scholar
• Peng Y, Li Z, Yang X, Yang L, He M, Zhang H, Wei X, et al. 2020. Relation between cadmium body burden and cognitive function in older men: a cross-sectional study in China. Chemosphere. 250:126535.
   PubMed Web of Science ®Google Scholar
• Pulido G, Treviño S, Brambila E, Vazquez-Roque R, Moreno-Rodriguez A, Peña Rosas U, Moran-Perales JL, et al. 2019. The administration of cadmium for 2, 3 and 4 months causes a loss of recognition memory, promotes neuronal hypotrophy and apoptosis in the hippocampus of rats. Neurochem Res. 44(2):485–497.
   PubMed Web of Science ®Google Scholar
• Regier DA, Kuhl EA, Kupfer DJ. 2013. The DSM-5: classification and criteria changes. World Psychiatry. 12(2):92–98.
   PubMed Web of Science ®Google Scholar
• Reyes-Hinojosa D, Lozada-Pérez CA, Zamudio Cuevas Y, López-Reyes A, Martínez-Nava G, Fernández-Torres J, Olivos-Meza A, et al. 2019. Toxicity of cadmium in musculoskeletal diseases. Environ Toxicol Pharmacol. 72:103219.
   PubMed Web of Science ®Google Scholar
• Richter P, Faroon O, Pappas RS. 2017. Cadmium and cadmium/zinc ratios and tobacco-related morbidities. Int J Environ Res Public Health. 14(10):1154.
   PubMed Web of Science ®Google Scholar
• Sasaki N, Carpenter DO. 2022. Associations between metal exposures and cognitive function in American Older Adults. Int J Environ Res Public Health. 19(4):2327.
   PubMed Web of Science ®Google Scholar
• Satarug S, G CG, D AV, Phelps KR. 2020. Cadmium and lead exposure, nephrotoxicity, and mortality. Toxics. 8(4):86.
   PubMed Web of Science ®Google Scholar
• Satarug S, Garrett SH, Sens MA, Sens DA. 2010. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 118(2):182–190.
   PubMed Web of Science ®Google Scholar
• Satarug S, Vesey DA, Gobe GC. 2017. Kidney cadmium toxicity, diabetes and high blood pressure: the perfect storm. Tohoku J Exp Med. 241(1):65–87.
   PubMed Web of Science ®Google Scholar
• Satoh M, Koyama H, Kaji T, Kito H, Tohyama C. 2002. Perspectives on cadmium toxicity research. Tohoku J Exp Med. 196(1):23–32.
   PubMed Web of Science ®Google Scholar
• Scheltens P, De Strooper B, Kivipelto M, Holstege H, Chételat G, Teunissen CE, Cummings J, van der Flier WM. 2021. Alzheimer’s disease. Lancet. 397(10284):1577–1590.
   PubMed Web of Science ®Google Scholar
• Slotnick MJ, Nriagu JO. 2006. Validity of human nails as a biomarker of arsenic and selenium exposure: a review. Environ Res. 102(1):125–139.
   PubMed Web of Science ®Google Scholar
• Sun BL, Li WW, Zhu C, Jin WS, Zeng F, Liu YH, Bu XL, et al. 2018. Clinical research on alzheimer’s disease: progress and perspectives. Neurosci Bull. 34(6):1111–1118.
   PubMed Web of Science ®Google Scholar
• Tang L, Qiu R, Tang Y, Wang S. 2014. Cadmium-zinc exchange and their binary relationship in the structure of Zn-related proteins: a mini review. Metallomics. 6(8):1313–1323.
   PubMed Web of Science ®Google Scholar
• Trivedi D. 2017. Cochrane Review Summary: mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations. Prim Health Care Res Dev. 18(6):527–528.
   PubMed Web of Science ®Google Scholar
• Waalkes MP. 2003. Cadmium carcinogenesis. Mutat Res. 533(1-2):107–120.
   PubMed Web of Science ®Google Scholar
• Wang B, Du Y. 2013. Cadmium and its neurotoxic effects. Oxid Med Cell Longev. 2013:898034.
   PubMed Web of Science ®Google Scholar
• Wang H, Abel GM, Storm DR, Xia Z. 2022. Adolescent cadmium exposure impairs cognition and hippocampal neurogenesis in C57BL/6 mice. Environ Toxicol. 37(2):335–348.
   PubMed Web of Science ®Google Scholar
• Wang H, Zhang L, Abel GM, Storm DR, Xia Z. 2018. Cadmium exposure impairs cognition and olfactory memory in male C57BL/6 Mice. Toxicol Sci. 161(1):87–102.
   PubMed Web of Science ®Google Scholar
• Xiao L, Zan G, Qin J, Wei X, Lu G, Li X, Zhang H, et al. 2021. Combined exposure to multiple metals and cognitive function in older adults. Ecotoxicol Environ Saf. 222:112465.
   PubMed Web of Science ®Google Scholar
• Xu L, Zhang W, Liu X, Zhang C, Wang P, Zhao X. 2018. Circulatory levels of toxic metals (Aluminum, Cadmium, Mercury, Lead) in patients with alzheimer’s disease: a quantitative meta-analysis and systematic review. J Alzheimers Dis. 62(1):361–372.
   PubMed Web of Science ®Google Scholar
• Yan LJ, Allen DC. 2021. Cadmium-induced kidney injury: oxidative damage as a unifying mechanism. Biomolecules. 11(11):1575.
   PubMed Web of Science ®Google Scholar
• Yang H, Tang J, Guo D, Zhao Q, Wen J, Zhang Y, Obianom ON, et al. 2020. Cadmium exposure enhances organic cation transporter 2 trafficking to the kidney membrane and exacerbates cisplatin nephrotoxicity. Kidney Int. 97(4):765–777.
   PubMed Web of Science ®Google Scholar
• Yi-bin C, Yin-Long J, Feng M. 2009. Study on Dietary Intake of Trace Elements and Cognitive Function in Some Sichuan Rural Elderly. J Environ Health. 26(07):565–568.
   Google Scholar
• Yu HT, Zhen J, Leng JY, Cai L, Ji HL, Keller BB. 2021. Zinc as a countermeasure for cadmium toxicity. Acta Pharmacol Sin. 42(3):340–346.
   PubMed Web of Science ®Google Scholar
• Zhang H, Reynolds M. 2019. Cadmium exposure in living organisms: a short review. Sci Total Environ. 678:761–767.
   PubMed Web of Science ®Google Scholar