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Hemoglobin
international journal for hemoglobin research
Volume 40, 2016 - Issue 4
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Original Article

Hb San Cataldo [β144(HC1)Lys→Thr; HBB: C.434A > C]: A New Hemoglobin Variant with Increased Affinity for Oxygen

Margherita VinciguerraDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Cristina PassarelloDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
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Filippo CassaràDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Filippo LetoDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Monica CannataDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Anna CrivelloDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Veronica Di SalvoDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and
,
Aurelio MaggioDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
&
Antonino GiambonaDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, ItalyCorrespondence[email protected]
 show all
Pages 223-227 | Received 17 Mar 2016, Accepted 07 Apr 2016, Published online: 02 Jun 2016

References

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  • Kister J, Prehu C, Riou J, et al. Two hemoglobin variants with an alteration of the oxygen-linked chloride binding: Hb Antananarivo [α1(NA1)Val→Gly] and Hb Barbizon [β144(HC1)Lys→Met]. Hemoglobin. 1999;23(1):21–32
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