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Research Articles

Design and evaluation of molecular organogel based on folic acid as a potential green drug carrier for oral route

ORCID Icon, ORCID Icon & ORCID Icon
Pages 367-373 | Received 22 Oct 2021, Accepted 22 Aug 2022, Published online: 12 Sep 2022

References

  • Cornwell DJ, Smith DK. Expanding the scope of gels – combining polymers with low-molecular-weight gelators to yield modified self-assembling smart materials with high-tech applications. Mater Horiz. 2015;2(3):279–293.
  • Esposito CL, Kirilov P, Roullin VG. Organogels, promising drug delivery systems: an update of state-of-the-art and recent applications. J Control Release. 2018;271:1–20.
  • Murdan S. Organogels in drug delivery. Expert Opin Drug Deliv. 2005;2(3):489–505.
  • Vintiloiu A, Leroux J-C. Organogels and their use in drug delivery — a review. J Control Release. 2008;125(3):179–192.
  • Patel D, Patel V. Development and characterization of pluronic lecithin organogel containing fluocinolone acetonide. Drug Dev Ind Pharm. 2021;47(3):377–384.
  • Wang K, Jia Q, Han F, et al. Self-assembled l-alanine derivative organogel as in situ drug delivery implant: characterization, biodegradability, and biocompatibility. Drug Dev Ind Pharm. 2010;36(12):1511–1521.
  • Jibry N, Heenan RK, Murdan S. Amphiphilogels for drug delivery: formulation and characterization. ‏Pharm Res. 2004;21(10):1852–1861.
  • Skilling KJ, Citossi F, Bradshaw TD, et al. Insights into low molecular mass organic gelators: a focus on drug delivery and tissue engineering applications. Soft Matter. 2014;10(2):237–256.
  • Weiss RG. The past, present, and future of molecular gels. What is the status of the field, and where is it going? J Am Chem Soc. 2014;136(21):7519–7530.
  • Pianowski ZL, Karcher J, Schneider K. Photoresponsive self-healing supramolecular hydrogels for light-induced release of DNA and doxorubicin. Chem Commun. 2016;52(15):3143–3146.
  • Suzuki M, Hanabusa K. l-Lysine-based low-molecular-weight gelators. Chem Soc Rev. 2009;38(4):967–975.
  • Jung JH, Ono Y, Sakurai K, et al. Novel vesicular aggregates of crown-appended cholesterol derivatives which act as gelators of organic solvents and as templates for silica transcription. J Am Chem Soc. 2000;122(36):8648–8653.
  • Abdallah DJ, Weiss RG. n-Alkanes gel n-alkanes (and many other organic liquids). Langmuir. 2000;16(2):352–355.
  • Murdan S, Gregoriadis G, Florence AT. Novel sorbitan monostearate organogels. J Pharm Sci. 1999;88(6):608–614.
  • Singh VK, Pramanik K, Ray SS, et al. Development and characterization of sorbitan monostearate and sesame oil-based organogels for topical delivery of antimicrobials. AAPS PharmSciTech. 2015;16(2):293–305.
  • Singh VK, Pal K, Pradhan DK, et al. Castor oil and sorbitan monopalmitate based organogel as a probable matrix for controlled drug delivery. J Appl Polym Sci. 2013;130(3):1503–1515.
  • Casuso P, Carrasco P, Loinaz I, et al. Converting drugs into gelators: supramolecular hydrogels from N-acetyl-l-cysteine and coinage-metal salts. Org Biomol Chem. 2010;8(23):5455–5458.
  • Vemula PK, Cruikshank GA, Karp JM, et al. Self-assembled prodrugs: an enzymatically triggered drug-delivery platform. Biomaterials. 2009;30(3):383–393.
  • Moysan E, González-Fernández Y, Lautram N, et al. An innovative hydrogel of gemcitabine-loaded lipid nanocapsules: when the drug is a key player of the nanomedicine structure. Soft Matter. 2014;10(11):1767–1777.
  • Eichholzer M, Tönz O, Zimmermann R. Folic acid: a public-health challenge. Lancet. 2006;367(9519):1352–1361.
  • Stanger O. Physiology of folic acid in health and disease. Curr Drug Metab. 2002;3(2):211–223.
  • Kamikawa Y, Nishii M, Kato T. Self-assembly of folic acid derivatives: induction of supramolecular chirality by hierarchical chiral structures. Chemistry. 2004;10(23):5942–5951.
  • Hao C, Gao J, Wu Y, et al. Design of folic acid based supramolecular hybrid gel with improved mechanical properties in NMP/H2O for dye adsorption. React Funct Polym. 2018;122:140–147.
  • Ranjan R, Rawat K, Bohidar H. Folic acid supramolecular ionogels. Phys Chem Chem Phys. 2017;19(34):22934–22945.
  • Biamonte AR, Schneller GH. A study of folic acid stability in solutions of the B complex vitamins. J Am Pharm Assoc Am Pharm Assoc. 1951;40(7):313–320.
  • Vignesh M, Sivakumar M, Parkavi V, et al. Stabilization of folic acid in liquid dosage form: formulation development, method validation and comparative analysis. Int J Pharm Chem Sci. 2012;1:332–338.
  • Fowles JR, Banton MI, Pottenger LH. A toxicological review of the propylene glycols. Crit Rev Toxicol. 2013;43(4):363–390.
  • Bellavinha KR, Silva-Barcellos NM, Souza JB, et al. Folic acid: a biopharmaceutical evaluation. Pharm Dev Technol. 2015;20(6):730–737.
  • Wu Z, Li X, Hou C, et al. Solubility of folic acid in water at pH values between 0 and 7 at temperatures (298.15, 303.15, and 313.15) K. J Chem Eng Data. 2010;55(9):3958–3961.
  • Anand O, Yu LX, Conner DP, et al. Dissolution testing for generic drugs: an FDA perspective. AAPS J. 2011;13(3):328–335.
  • Martin B, Brouillet F, Franceschi S, et al. Evaluation of organogel nanoparticles as drug delivery system for lipophilic compounds. AAPS PharmSciTech. 2017;18(4):1261–1269.
  • Dick MI, Harrison IT, Farrer K. The thermal stability of folic (pteroylglutamic) acid. Aust J Exp Biol Med Sci. 1948;26(Pt 3):239–244.
  • Neves DA, Lobato K, Angelica RS, et al. Thermal and in vitro digestion stability of folic acid in bread. J Food Compos Anal. 2019;84:103311.
  • Tan YT, Abdulameer SA, Peh KK, et al. Polyethylene glycol–phosphatidylethanolamine conjugate as a pulmonary nanocarrier for poorly soluble drug. Lat Am J Pharm. 2012;31:68–77.
  • Gazzali AM, Lobry M, Colombeau L, et al. Stability of folic acid under several parameters. Eur J Pharm Sci. 2016;93:419–430.
  • Kumara JV, Ravikumara N, Madhusudhan B. Evaluation of surfactants-assisted folic acid-loaded pectin submicrospheres: characterization and hemocompatibility assay. Indian J Clin Biochem. 2016;31(4):390–401.
  • Kumara N, Madhusudhan B. Evaluation of anticancer efficacy of daidzein-loaded poly(d,l)lactic acid nanoparticles. J Bionanosci. 2011;5(2):122–129.
  • Wu S, Gao J, Emge TJ, et al. Solvent-induced polymorphic nanoscale transitions for 12-hydroxyoctadecanoic acid molecular gels. Cryst Growth Des. 2013;13(3):1360–1366.
  • He Y, Wang X, Jin P, et al. Complexation of anthracene with folic acid studied by FTIR and UV spectroscopies. Spectrochim Acta A Mol Biomol Spectrosc. 2009;72(4):876–879.
  • Doan CD, Van de Walle D, Dewettinck K, et al. Evaluating the oil-gelling properties of natural waxes in rice bran oil: rheological, thermal, and microstructural study. J Am Oil Chem Soc. 2015;92(6):801–811.
  • Rogers MA, Wright AJ, Marangoni AG. Nanostructuring fiber morphology and solvent inclusions in 12-hydroxystearic acid/canola oil organogels. Curr Opin Colloid Interface Sci. 2009;14(1):33–42.
  • Liu S, Yu W, Zhou C. Solvents effects in the formation and viscoelasticity of DBS organogels. Soft Matter. 2013;9(3):864–874.
  • Liao L, Zhong X, Jia X, et al. Supramolecular organogels fabricated with dicarboxylic acids and primary alkyl amines: controllable self-assembled structures. RSC Adv. 2020;10(49):29129–29138.
  • Rogers MA, Spagnuolo PA, Wang TM, et al. A potential bioactive hard-stock fat replacer comprised of a molecular gel. Food Sci Nutr. 2017;5(3):579–587.
  • Lee JH, Park J, Park J-W, et al. Supramolecular gels with high strength by tuning of calix [4] arene-derived networks. Nat Commun. 2015;6(1):1–9.
  • Ojeda-Serna IE, Rocha-Guzmán NE, Gallegos-Infante JA, et al. Water-in-oil organogel based emulsions as a tool for increasing bioaccessibility and cell permeability of poorly water-soluble nutraceuticals. Food Res Int. 2019;120:415–424.
  • Acevedo-Fani A, Soliva-Fortuny R, Martín-Belloso O. Photo-protection and controlled release of folic acid using edible alginate/chitosan nanolaminates. J Food Eng. 2018;229:72–82.

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