Use of Plant Viruses for Production of Plant-Derived Vaccines

REFERENCES

• Ahlquist , P. , French , R. , Janda , M. and Loesch-Fries , L. S. 1984 . Multicomponent RNA plant virus infection derived from clones viral cDNA . Proc. Natl. Acad. Sci. USA , 81 : 7066 – 7070 . [CSA]
   PubMed Web of Science ®Google Scholar
• Arntzen , C. 2005 . Plant-derived vaccines and antibodies: potential and limitations . Vaccine , 23 : 1753 – 1756 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   Google Scholar
• Bachmann , M. F. and Kopf , M. 2002 . Balancing protective immunity and immunopathology . Curr. Opin. Immunol. , 14 : 413 – 419 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bakker , H. , Bardor , M. , Molthoff , J. W. , Gomord , V. , Elbers , I. , Stevens , L. H. , Jordi , W. , Lommen , A. , Faye , L. , Lerouge , P. and Bosch , D. 2001 . Galactose-extended glycans of antibodies produced by transgenic plants . Proc. Natl. Acad. Sci. USA , 98 : 2899 – 2904 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Belanger , H. , Fleysh , N. , Cox , S. , Bartman , G. , Deka , D. , Trudel , M. , Koprowski , H. and Yusibov , V. 2000 . Human respiratory syncytial virus vaccine antigen produced in plants . FASEB Journal , 14 : 2323 – 2328 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bendandi , M. , Gocke , C. D. , Kobrin , C. B. , Benko , F. A. , Sternas , L. A. , Pennington , R. , Watson , T. M. , Reynolds , C. W. , Gause , B. L. , Duffey , P. L. , Jaffe , E. S. , Creekmore , S. P. , Longo , D. L. and Kwak , L. W. 1999 . Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma . Nat. Med. , 5 : 1171 – 1177 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Biemelt , S. , Sonnewald , U. , Galmbacher , P. , Willmitzer , L. and Muller , M. 2003 . Production of human papillomavirus type 16 virus-like particles in transgenic plants . J. Virol. , 77 : 9211 – 9720 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Boisgerault , F. , Moron , G. and Leclerc , C. 2002 . Virus-like particles: a new family of delivery systems . Expert Rev. Vaccines , 1 : 101 – 109 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMedGoogle Scholar
• Brennan , F. R. , Jones , T. D. , Gilleland , L. B. , Bellaby , T. , Xu , F. , North , P. C. , Thompson , A. , Staczek , J. , Lin , T. , Johnson , J. E. , Hamilton , W. D. and Gilleland , H. E. Jr. 1999 . Pseudomonas aeruginosa outer-membrane protein F epitopes are highly immunogenic in mice when expressed on a plant virus . Microbiology , 145 : 211 – 220 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Carrillo , C. , Wigdorovitz , A. , Oliveros , J. C. , Zamorano , P. I. , Sadir , A. M. , Gomez , N. , Salinas , J. , Escribano , J. M. and Borca , M. V. 1998 . Protective immune response to foot-and-mouth disease virus with VP1 expressed in transgenic plants . J. Virol. , 72 : 1688 – 1690 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Chackerian , B. , Lowy , D. R. and Schiller , J. T. 1999 . Induction of autoantibodies to mouse CCR5 with recombinant papillomavirus particles . Proc. Natl. Acad. Sci. USA , 96 : 2373 – 2378 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Chackerian , B. , Lowy , D. R. and Schiller , J. T. 2001 . Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies . J. Clin. Invest. , 108 : 415 – 423 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Chapman , S. , Kavanagh , T. and Baulcombe , D. 1992 . Potato virus X as a vector for gene expression in plants . Plant J. , 2 : 549 – 557 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Coperman , R. J.H. , Hartman , J. R. and Watterson , J. C. 1969 . Tobacco mosaic virus concentration in inoculated and systemically infected tobacco leaves . Phytopathology , 59 : 1012 – 1013 . [CSA]
   Google Scholar
• Coscia , M. and Kwak , L. W. 2004 . Therapeutic idiotype vaccines in B lymphoproliferative diseases . Expert Opin. Biol. Ther. , 4 : 959 – 963 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Dalsgaard , K. , Uttenthal , A , Jones , T. D. , Xu , F. , Merryweather , A. , Hamilton , W. D. O. , Langeveld , J. P. M. , Boshuizen , R. S. , Kamstrup , S. , Lomonossoff , G. P. , Porta , C. , Vela , C. , Casal , J. I. , Meloen , R. H. and Rodgers , P. B. 1997 . Plant derived vaccines protects target animals against a viral disease . Nat. Biotechnol. , 15 : 248 – 252 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Dawson , W. O. , Beck , D. L. , Knorr , D. A. and Grantham , G. L. 1986 . cDNA cloning of the complete genome of tobacco mosaic virus and production of infectious transcripts . Proc. Natl. Acad. Sci. USA , 83 : 1832 – 1836 . [CSA]
   PubMed Web of Science ®Google Scholar
• Dolja , V. V. , McBride , H. J. and Carrington , J. C. 1992 . Tagging of plant potyvirus replication and movement by insertion of beta-glucuronidase into the viral polyprotein . Proc. Natl. Acad. Sci. USA , 89 : 10208 – 10212 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Donson , J. , Kearney , C. M. , Hilf , M. E. and Dawson , W. O. 1991 . Systemic expression of a bacterial gene by a tobacco mosaic virus-based vector . Proc. Natl. Acad. Sci. USA , 88 : 7204 – 7208 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Durrani , Z. , McInerney , T. L. , McLain , L. , Jones , T. , Bellaby , T. , Brennan , F. R. and Dimmock , N. J. 1998 . Intranasal immunization with a plant virus expressing a peptide from HIV-1 gp41 stimulates better mucosal and systemic HIV-1-specific IgA and IgG than oral immunization . J. Immuno. Methods , 220 : 93 – 103 . [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Faye , L. , Boulaflous , A. , Benchabane , M. , Gomord , V. and Michaud , D. 2005 . Protein modifications in the plant secretory pathway: current status and practical implications in molecular pharming . Vaccine , 23 : 1770 – 1778 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Fitchen , J. , Beachy , R. N. and Hein , M. B. 1995 . Plant virus expressing hybrid coat protein with added muring epitope elicits autoantibody response . Vaccine , 13 : 1051 – 1057 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMedGoogle Scholar
• Gilleland , H. E. , Gilleland , L. B. , Staczek , J. , Harty , R. N. , Garcia-Sastre , A. , Pale , P. , Brennen , F. R. , Hamilton , W. D. , Bendahmane , M. and Beachy , R. N. 2000 . Chimeric animal and plant viruses expressing eptiopes of outer membrane protein F as a combined vaccine against Pseudomonas aeruginosa lung infection . FEMS Immunol. Med. Microbiol. , 27 : 291 – 297 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Grill , L. K. 1993 . Tobacco mosaic virus as a gene expression vector . Agro Food Industry Hi-Tech , : 20 – 23 . Nov/Dec[CSA]
   Google Scholar
• Hagiwara , Y. , Peremyslov , V. V. and Dolja , V. V. 1999 . Regulation of closterovirus gene expression examined by insertion of a self-processing reporter and by northern hybridization . J. Virol. , 73 : 7988 – 7993 . [PUBMED] [INFOTRIEVE] [CSA]
   Google Scholar
• Hamamoto , H. , Sugiyama , Y. , Nadagawa , N. , Hashida , E. , Matsunaga , Y. , Takemoto , S. , Watanabe , Y. and Okada , Y. 1993 . A new tobacco mosaic virus vector and its use for the systemic production of angiotensin-I-converting enzyme inhibitor in transgenic tobacco and tomato . Nat. Biotechnol. , 11 : 930 – 932 . [CSA] [CROSSREF]
   Google Scholar
• Harper , D. M. , Franco , E. L. , Wheeler , C. , Ferris , D. G. , Jenkins , D. , Schuind , A. , Zahaf , T. , Innis , B. , Naud , P. , De Carvalho , N. S. , Roteli-Martins , C. M. , Teixeira , J. , Blatter , M. M. , Korn , A. P. , Quint , W. and Dubin , G. 2004 . Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial . Lancet , 364 : 1757 – 1765 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Herrera-Estrella , L. , Simpson , J. and Martinez-Trujillo , M. 2005 . Transgenic plants: an historical perspective . Methods Mol. Biol. , 286 : 3 – 32 . [PUBMED] [INFOTRIEVE] [CSA]
   Google Scholar
• Horn , M. E. , Pappu , K. M. , Bailey , M. R. , Clough , R. C. , Barker , M. , Jilka , J. M. , Howard , J. A. and Streatfield , S. J. 2003 . Advantageous features of plant-based systems for the development of HIV vaccines . J. Drug. Target , 11 : 539 – 545 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hsu , F. J. , Caspar , C. B. , Czerwinski , D. , Kwak , L. W. , Liles , T. M. , Syrengelas , A. , Taidi-Laskowski , B. and Levy , R. 1997 . Tumor-specific idiotype vaccines in the treatment of patients with B-cell lymphoma—long-term results of a clinical trial . Blood , 89 : 3129 – 3135 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Hsu , F. J. , Kwak , L. , Campbell , M. , Liles , T. , Czerwinski , D. , Hart , S. , Syrengelas , A. , Miller , R. and Levy , R. 1993 . Clinical trials of idiotype-specific vaccine in B-cell lymphomas . Ann. N.Y. Acad. Sci. , 690 : 385 – 387 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Kong , Q. , Richter , L. , Yang , Y. F. , Arntzen , C. J. , Mason , H. S. and Thanavala , Y. 2001 . Oral immunization with hepatitis B surface antigen expressed in transgenic plants . Proc. Natl. Acad. Sci. USA , 98 : 11539 – 11544 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Koutsky , L. A. , Ault , K. A. , Wheeler , C. M. , Brown , D. R. , Barr , E. , Alvarez , F. B. , Chiacchierini , L. M. and Jansen , K. U. 2002 . A controlled trial of a human papillomavirus type 16 vaccine . N. Engl. J. Med. , 347 : 1645 – 1651 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kumagai , M. H. , Turpen , T. H. , Weinzettl , N. , Della-Cioppa , G. , Turpen , A. M. , Donson , J. , Hilf , M. E. , Grantham , G. L. , Dawson , W. O. , Chow , T. P. , Piatak , M. and Grill , L. K. 1993 . Rapid, high-level expression of biologically active α -trichosanthin in transfected plants by an RNA viral vector . Proc. Natl. Acad. Sci. USA , 90 : 427 – 430 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Kwak , L. W. , Campbell , M. J. , Czerwinski , D. K. , Hart , S. , Miller , R. A. and Levy , R. 1992 . Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors . N. Engl. J. Med. , 327 : 1209 – 1215 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Lacomme , C. , Pogue , G. P. , Wilson , T. M.A. and Santa Cruz , S. 2001 . “ Plant viruses as gene expression vectors ” . In Genetically Engineered Viruses , Edited by: Ring , C. J. A. and Blair , E. D. 59 – 99 . Oxford, UK : BIOS Scientific Publishers, Ltd .
   Google Scholar
• Lamphear , B. J. , Streatfield , S. J. , Jilka , J. M. , Brooks , C. A. , Barker , D. K. , Turner , D. D. , Delaney , D. E. , Garcia , M. , Wiggins , B. , Woodard , S. L. , Hood , E. E. , Tizard , I. R. , Lawhorn , B. and Howard , J. A. 2002 . Delivery of subunit vaccines in maize seed . J. Control Release , 85 : 169 – 180 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lamphear , B. J. , Jilka , J. M. , Kesl , L. , Welter , M. , Howard , J. A. and Streatfield , S. J. 2004 . A corn-based delivery system for animal vaccines: an oral transmissible gastroenteritis virus vaccine boosts lactogenic immunity in swine . Vaccine , 22 : 2420 – 2424 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Langeveld , J. P. , Brennan , F. R. , Martinez-Torrecuadrada , J. L. , Jones , T. D. , Boshuizen , R. S. , Vela , C. , Casal , J. I. , Kamstrup , S. , Dalsgaard , K. , Meloen , R. H. , Bendig , M. M. and Hamilton , W. D. 2001 . Inactivated recombinant plant virus protects dogs from a lethal challenge with canine parvovirus . Vaccine , 19 : 3661 – 3670 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lechner , F. , Jegerlehner , A. , Tissot , A. C. , Maurer , P. , Sebbel , P. , Renner , W. A. , Jennings , G. T. and Bachmann , M. F. 2002 . Virus-like particles as a modular system for novel vaccines . Intervirology , 45 : 212 – 217 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Liu , L. , Cañizares , M. C. , Monger , W. , Perrin , Y. , Tsakiris , E. , Porta , C. , Shariat , N. , Nicholson , L. and Lomonossoff , G. P. 2005 . Cowpea moasaic virus-based systems for the production of antigens and antibodies in plants . Vaccine , 23 : 1788 – 1792 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Marusic , C. , Rizza , P , Lattanzi , L. , Mancini , C , Spada , M. , Belardelli , F. , Benvenuto , E. and Capone , I. 2001 . Chimeric plant virus particles as immunogens for inducing murine and human immune responses against human immunodeficiency virus type 1 . J. Virol. , 75 : 8434 – 8439 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Mason , H. S. , Ball , J. M. , Shi , J. J. , Jiang , X. , Estes , M. K. and Arntzen , C. J. 1996 . Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice . Proc. Natl. Acad. Sci. USA , 93 : 5335 – 5340 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Mason , H. S. , Haq , T. A. , Clements , J. D. and Arntzen , C. J. 1998 . Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene . Vaccine , 16 : 1336 – 1343 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Mason , H. S. , Lam , D. M. and Arntzen , C. J. 1992 . Expression of hepatitis B surface antigen in transgenic plants . Proc. Natl. Acad. Sci. USA , 89 : 11745 – 11749 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• McCormick , A. A. , Kumagai , M. H. , Hanley , K. , Turpen , T. H. , Hakim , I. , Grill , L. K. , Tuse , D. , Levy , S. and Levy , R. 1999 . Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single-chain Fv epitopes in tobacco plants . Proc. Natl. Acad. Sci. USA , 96 : 703 – 708 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• McCormick , A. A. , Reinl , S. J. , Cameron , T. I. , Vojdani , F. , Fronefield , M. , Levy , R. and Tusé , D. T. 2003 . Individualized human scFv vaccines produced in plants: humoral anti-idiotype responses in vaccinated mice confirm relevance to the tumor Ig . J. Immunol. Meth. , 278 : 95 – 104 . [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• McLain , L. , Durrani , Z. , Wisniewski , L. A. , Porta , C. , Lomonossoff , G. P. and Dimmock , N. J. 1996 . Stimulation of neutralizing antibodies to human immunodeficiency virus type 1 in three strains of mice immunized with a 22 amino acid peptide of gp41 expressed on the surface of a plant virus . Vaccine , 14 : 799 – 810 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• McLain , L. , Porta , C. , Lomonossoff , G. P. , Durrani , Z. and Dimmock , N. J. 1995 . Human immunodeficiency virus type 1-neutralizing antibodies raised to a glycoprotein 41 peptide expressed on the surface of a plant virus . AIDS Res. Hum Retroviruses , 11 : 327 – 334 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Modelska , A. , Dietzschold , B. , Sleysh , N. , Fu , Z. F. , Steplewski , K. , Hooper , D. C. , Koprowski , H. and Yusibov , V. 1998 . Immunization against rabies with plant-derived antigen . Proc. Natl. Acad. Sci. USA , 95 : 2481 – 2485 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Natilla , A. , Piazzolla , G. , Nuzzaci , M. , Saldarelli , P. , Tortorella , C. , Antonaci , S. and Piazzolla , P. 2004 . Cucumber mosaic virus as carrier of a hepatitis C virus-derived epitope . Arch. Virol. , 149 : 137 – 154 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Nemchinov , L. G. , Liang , T. J. , Rifaat , M. M. , Mazyad , H. M. , Hadidi , A. and Keith , J. M. 2000 . Development of a plant-derived subunit vaccine candidate against hepatitis C virus . Arch. Virol. , 145 : 2557 – 2573 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Nicholas , B. L. , Brennan , F. R. , Martinez-Torrecuadrada , J. L. , Casal , J. I. , Hamilton , W. D. and Wakelin , D. 2002 . Characterization of the immune response to canine parvovirus induced by vaccination with chimaeric plant viruses . Vaccine , 20 : 2727 – 2734 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Palacpac , N. Q. , Yoshida , S. , Sakai , H. , Kimura , Y. , Fujiyama , K. , Yoshida , T. and Seki , T. 1999 . Stable expression of human beta1,4-galactosyltransferase in plant cells modifies N-linked glycosylation patterns . Proc. Natl. Acad. Sci. USA , 96 : 4692 – 4697 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Pérez-Filgueira , D. M. , Brayfield , B. P. , Phiri , S. , Borca , M. V. , Wood , C. and Morris , T. J. 2004 . Preserved antigenicity of HIV-1 p24 produced and purified in high yields from plants inoculated using a tobacco mosaic virus (TMV)-derived vector . J. Virol. Meth. , 121 : 201 – 208 . [CSA] [CROSSREF]
   Google Scholar
• Pérez-Filgueira , D. M. , Mozgovoj , M. , Wigdorovitz , A. , Dus Santos , M. J. , Parreño , V. , Trono , K. , Fernandez , F. M. , Carrillo , C. , Babiuk , L. A. , Morris , T. J. and Borca , M. V. 2004 . Passive protection of bovine rotavirus (BRV) infection induced by a BRV VP8 produced in plants using a TMV-based vector . Arch. Virol. , 149 : 2337 – 2348 . [CSA] [CROSSREF]
   Google Scholar
• Perez Filgueira , D. M. , Zamorano , P. I. , Dominguez , M. G. , Taboga , O. , Del Medico Zajac , M. P. , Puntel , M. , Romera , S. A. , Morris , T. J. , Borca , M. V. and Sadir , A. M. 2003 . Bovine herpes virus G-D protein produced in plants using a recombinant tobacco mosaic virus (TMV) vector possesses authentic antigenicity . Vaccine , 21 : 4201 – 4209 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Pogue , G. P. , Lindbo , J. A. , Garger , S. J. and Fitzmaurice , W. P. 2002 . Making an ally from an enemy: plant virology and the new agriculture . Annu. Rev. Phytopathol. , 40 : 45 – 74 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Pogue , G. P. , Lindbo , J. A. , McCulloch , M. J. , Lawrence , J. E. , Gross , C. S. and Garger , S. J. Parvovirus vaccine as viral coat protein fusions . United States Patent #6,730,306. . 2004 .
   Google Scholar
• Porta , C. , Spall , V. E. , Loveland , J. , Johnson , J. E. , Barker , P. J. and Lomonossoff , G. P. 1994 . Development of cowpea mosaic virus as a high-yielding system for the presentation of foreign peptides . Virology , 202 : 949 – 955 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Quaedvlieg , N. E. , Schlaman , H. R. , Admiraal , P. C. , Wijting , S. E. , Stougaard , J. and Spaink , H. P. 1998 . Fusions between green fluorescent protein and beta-glucuronidase as sensitive and vital bifunctional reporters in plants . Plant Mol. Biol. , 38 : 861 – 873 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rabindran , S. and Dawson , W. O. 2001 . Assessment of recombinants that arise from the use of a TMV-based transient expression vector . Virology , 284 : 182 – 189 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Reddy , S. A. , Czerwinski , D. , Rajapaksa , R. , Reinl , S. , Garger , S. J. , Cameron , T. I. , McCormick , A. A. , Barrett , J. , Novak , J. , Tusé , D. , Holtz , R. B. and Levy , R. 2002 . Plant derived single-chain Fv idiotype vaccines are safe and immunogenic in patients with follicular lymphoma: results of a phase I study . Blood , 100 : 163a Proceedings of the 44th Annual Conference of the American Society of Hematology[CSA]
   Google Scholar
• Rennermalm , A. , Li , Y. H. , Bohaufs , L. , Jarstrand , C. , Brauner , A. , Brennan , F. R. and Flock , J. I. 2001 . Antibodies against a truncated Staphylococcus aureus fibronectin-binding protein protect against dissemination of infection in the rat . Vaccine , 19 : 3376 – 3383 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Richter , L. J. , Thanavala , Y. , Arntzen , C. J. and Mason , H. S. 2000 . Production of hepatitis B surface antigen in transgenic plants for oral immunization . Nat. Biotechnol. , 18 : 1167 – 1171 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ruedl , C. , Storni , T. , Lechner , F. , Bachi , T. and Bachmann , M. F. 2002 . Cross-presentation of virus-like particles by skin-derived CD8(-) dendritic cells: a dispensable role for TAP . Eur. J. Immunol. , 32 : 818 – 825 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Scholthof , H. B. , Scholthof , K. B. and Jackson , A. O. 1996 . Plant virus gene vectors for transient expression of foreign proteins in plants . Annu. Rev. Phytopathol. , 34 : 299 – 323 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Shivprasad , S. , Pogue , G. P. , Lewandowski , D. J. , Hidalgo , J. , Donson , J. , Grill , L. K. and Dawson , W. O. 1999 . Heterologous sequences greatly affect foreign gene expression in tobacco mosaic virus-based vectors . Virology , 255 : 312 – 323 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Smith , M. L. , Richter , L. , Arntzen , C. J. , Shuler , M. L. and Mason , H. S. 2003 . Structural characterization of plant-derived hepatitis B surface antigen employed in oral immunization studies . Vaccine , 21 : 4011 – 4021 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Staczek , J. , Bendahmane , M. , Gilleland , L. B. , Beachy , R. N. and Gilleland , H. E. Jr. 2000 . Immunization with a chimeric tobacco mosaic virus containing an epitope of outer membrane protein F of Pseudomonas aeruginosa provides protection against challenge with P. aeruginosa . Vaccine , 18 : 2266 – 2274 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sugiyama , Y. , Hamamoto , H. , Takemoto , S. , Watanabe , Y. and Okada , Y. 1995 . Systemic production of foreign peptides on the particle surface of tobacco mosaic virus . FEBS Let. , 359 : 247 – 250 . [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tackaberry , E. S. , Dudani , A. K. , Prior , F. , Tocchi , M. , Sardana , R. , Altosaar , I. and Ganz , P. R. 1999 . Development of biopharmaceuticals in plant expression systems: cloning, expression and immunological reactivity of human cytomegalovirus glycoprotein B (UL55) in seeds of transgenic tobacco . Vaccine , 17 : 3020 – 3029 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tackaberry , E. S. , Prior , F. , Bell , M. , Tocchi , M. , Porter , S. , Mehic , J. , Ganz , P. R. , Sardana , R. , Altosaar , I. and Dudani , A. 2003 . Increased yield of heterologous viral glycoprotein in the seeds of homozygous transgenic tobacco plants cultivated underground . Genome , 46 : 521 – 526 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tacket , C. O. , Mason , H. S. , Losonsky , G. , Clements , J. D. , Levine , M. M. and Arntzen , C. J. 1998 . Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato . Nat. Med. , 4 : 607 – 609 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tacket , C. O. , Mason , H. S. , Losonsky , G. , Estes , M. K. , Levine , M. M. and Arntzen , C. J. 2000 . Human immune responses to a novel norwalk virus vaccine delivered in transgenic potatoes . J. Infect. Dis. , 182 : 302 – 305 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tacket , C. O. , Sztein , M. B. , Losonsky , G. A. , Wasserman , S. S. and Estes , M. K. 2003 . Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers . Clin. Immunol. , 108 : 241 – 247 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Thanavala , Y. , Mahoney , M. , Pal , S. , Scott , A. , Richter , L. , Natarajan , N. , Goodwin , P. , Arntzen , C. J. and Mason , H. S. 2005 . Immunogenicity in humans of an edible vaccine for hepatitis B . Proc. Natl. Acad. Sci. USA , 102 : 3378 – 3382 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Thanavala , Y. , Yang , Y. F. , Lyons , P. , Mason , H. S. and Arntzen , C. 1995 . Immunogenicity of transgenic plant-derived hepatitis B surface antigen . Proc. Natl. Acad. Sci. USA , 92 : 3358 – 3361 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• The World Report . 1996 . Fighting disease, fostering development, 1996 , 1 – 43 . Geneva, , Switzerland : The World Health Organization Press .
   Google Scholar
• Turpen , T. H. 1999 . Tobacco mosaic virus and the virescence of biotechnology . Philos. Trans. R. Soc. Lond. B. Biol. Sci. , 354 : 665 – 673 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   Google Scholar
• Turpen , T. H. , Reinl , S. J. , Charoenvit , Y. , Hoffman , S. L. , Fallarme , V. and Grill , L. K. 1995 . Malarial epitopes expressed on the surface of recombinant tobacco mosaic virus . Nat. Biotechnol. , 13 : 53 – 57 . [CSA] [CROSSREF]
   Google Scholar
• Turpen , T. H. , Turpen , A. M. , Weinzettl , N. , Kumagai , M. H. and Dawson , W. O. 1993 . Transfection of whole plants from wounds inoculated with Agrobacterium tumefaciens containing cDNA of tobacco mosaic virus . J. Virol. Methods , 42 : 227 – 239 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Usha , R. , Rohll , J. B. , Spall , V. E. , Shanks , M. , Maule , A. J. , Johnson , J. E. and Lomonossoff , G. P. 1993 . Expression of an animal virus antigenic site on the surface of a plant virus particle . Virology , 197 : 366 – 374 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• van Ree , R. , Cabanes-Macheteau , M. , Akkerdaas , J. , Milazzo , J. P. , Louthelier-Bourhis , C. , Rayon , C. , Villalba , M. , Koppelman , S. , Aalberse , R. , Rodriguez , R. , Faye , L. and Lerouge , P. 2000 . Beta(1,2)-xylose and alpha (1,3)-fucose residues have a strong contribution in IgE binding to plant glycoallergens . J. Biol. Chem. , 275 : 11451 – 11458 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Varrelmann , M. and Maiss , E. 2000 . Mutations in the coat protein gene of plum pox virus suppress particle assembly, heterologous encapsidation and complementation in transgenic plants of Nicotiana benthamiana . J. Gen. Virol. , 81 : 567 – 576 . [PUBMED] [INFOTRIEVE] [CSA]
   Google Scholar
• Varsani , A. , Williamson , A. L. , Rose , R. C. , Jaffer , M. and Rybicki , E. P. 2003 . Expression of Human papillomavirus type 16 major capsid protein in transgenic Nicotiana tabacum cv. Xanthi . Arch. Virol. , 148 : 1771 – 1786 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Warzecha , H. , Mason , H. S. , Lane , C. , Tryggvesson , A. , Rybicki , E. , Williamson , A. L. , Clements , J. D. and Rose , R. C. 2003 . Oral immunogenicity of human papillomavirus-like particles expressed in potato . J. Virol. , 77 : 8702 – 8711 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wigdorovitz , A. , Carrillo , C. , Dus Santos , M. J. , Trono , K. , Peralta , A. , Gomez , M. C. , Rios , R. D. , Franzone , P. M. , Sadir , A. M. , Escribano , J. M. and Borca , M. V. 1999 . Induction of a protective antibody response to foot and mouth disease virus in mice following oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1 . Virology , 255 : 347 – 353 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wigdorovitz , A. , Mozgovoj , M. , Santos , M. J. , Parreno , V. , Gomez , C. , Perez-Filgueira , D. M. , Trono , K. G. , Rios , R. D. , Franzone , P. M. , Fernandez , F. , Carrillo , C. , Babiuk , L. A. , Escribano , J. M. and Borca , M. V. 2004 . Protective lactogenic immunity conferred by an edible peptide vaccine to bovine rotavirus produced in transgenic plants . J. Gen. Virol. , 85 : 1825 – 1832 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wu , L. , Jiang , L. , Zhou , Z. , Fan , J. , Zhang , Q. , Zhu , H. , Han , Q. and Xu , Z. 2003 . Expression of foot-and-mouth disease virus in tobacco leaves using a tobacco mosaic virus-based vector . Vaccine , 21 : 4390 – 4398 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMedGoogle Scholar
• Yusibov , V. , Modelska , A. , Steplewski , K. , Agadjanyan , M. , Weiner , D. , Hooper , D. C. and Koprowski , H. 1997 . Antigens produced in plants by infection with chimeric plant viruses immunize against rabies virus and HIV-1 . Proc. Natl. Acad. Sci. USA , 94 : 5784 – 5788 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Zaitlin , M. and Israel , H. W. 1975 . “ Tobacco mosaic virus (type strain) ” . In C.M.I./A.A.B. Descriptions of Plant Viruses , UK : Wm. Culross and Son Ltd .
   Google Scholar
• Zhou , J. Y. , Cheng , L. Q. , Zheng , X. J. , Wu , J. X. , Shang , S. B. , Wang , J. Y. and Chen , J. G. 2004 . Generation of the transgenic potato expressing full-length spike protein of infectious bronchitis virus . J. Biotechnol. , 111 : 121 – 130 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
   PubMed Web of Science ®Google Scholar