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ORIGINAL ARTICLE

Response to Neoadjuvant Chemotherapy in Breast Cancer Could be Predictable by Measuring a Novel Serum Apoptosis Product, Caspase-Cleaved Cytokeratin 18: A Prospective Pilot Study

, M.D., , M.D., Ph.D., , M.D., , M.D., , M.D., , Ph.D., , M.D. & , M.D. show all
Pages 669-676 | Published online: 11 Jun 2009

REFERENCES

  • Fisher B., Bryant J., Wolmark N., Mamounas E., Brown A., et al. Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J. Clin. Oncol. 1998; 16(8)2672–2685, [INFOTRIEVE], [CSA]
  • Bonadonna G., Valagussa P., Brambilla C., Ferrari L., Moliterni A., et al. Primary chemotherapy in operable breast cancer: eight-year experience at the Milan Cancer Institute. J. Clin. Oncol. 1998; 16(1)93–100, [INFOTRIEVE], [CSA]
  • Scholl S. M., Pierga J. Y., Asselain B., Beuzeboc P., Dorval T., et al. Breast tumour response to primary chemotherapy predicts local and distant control as well as survival. Eur. J. Cancer. 1995; 31A(12)1969–1975, [INFOTRIEVE], [CROSSREF], [CSA]
  • Scholl S. M., Beuzeboc P., Haris A. L., Pierga J. Y., Asselain B., et al. Is primary chemotherapy useful for all patients with primary invasive breast cancer?. Recent Results Cancer Res. 1998; 152: 217–226, [INFOTRIEVE], [CSA]
  • Hickman J. A., Beere H. M., Wood A. C., Waters C. M., Parmar R. Mechanisms of cytotoxicity caused by antitumour drugs. Toxicol Lett. 1992; 64–65: 553–561, [INFOTRIEVE], [CROSSREF], [CSA]
  • Ohmori T., Podack E. R., Nishio K., Takahashi M., Miyahara Y., et al. Apoptosis of lung cancer cells caused by some anti-cancer agents (MMC, CPT-11, ADM) is inhibited by bcl-2. Biochem. Biophys. Res. Commun. 1993; 192(1)30–36, [INFOTRIEVE], [CROSSREF], [CSA]
  • Walton M. I., Whysong D., O'Connor P. M., Hockenbery D., Korsmeyer S. J., Kohn K. W. Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis. Cancer Res. 1993; 53(8)1853–1861, [INFOTRIEVE], [CSA]
  • Hagg M., Biven K., Ueno T., Rydlander L., Bjorklund P., Wiman K. G., Shoshan M., Linder S. A novel high-through-put assay for screening of pro-apoptotic drugs. Invest New Drugs. 2002; 20(3)253–259, [INFOTRIEVE], [CROSSREF], [CSA]
  • Meyn R. E., Stephens L. C., Hunter N. R., Milas L. Apoptosis in murine tumors treated with chemotherapy agents. Anticancer Drugs. 1995; 6(3)443–450, [INFOTRIEVE], [CROSSREF], [CSA]
  • Ellis P. A., Smith I. E., McCarthy K., Detre S., Salter J., Dowsett M. Preoperative chemotherapy induces apoptosis in early breast cancer. Lancet. 1997; 349(9055)849, [INFOTRIEVE], [CROSSREF], [CSA]
  • Caulin C., Salvasen G. S., Oshima R. G. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis. Cell Biol. 1997; 138(6)1379–1394, [CROSSREF], [CSA]
  • Ku N. O., Liao J., Omary M. B. Apoptosis generates stable fragments of human type I keratins. J Biol Chem. 1997; 272(52)33197–33203, [INFOTRIEVE], [CROSSREF], [CSA]
  • MacFarlane M., Merrison W., Dinsdale D., Cohen G. M. Active caspase sand cleaved cytokeratins ae sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis. J Cell Biol. 2000; 148(6)1239–1254, [INFOTRIEVE], [CROSSREF], [CSA]
  • Leers M. P., Kolgen W., Bjorklund V., Bergman T., Tribbick G., Persson B., Bjorklund P., Ramaekers F. C., Bjorklund B., Nap M., Jornvall H., Schutte B. Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol. 1999; 187(5)567–572, [INFOTRIEVE], [CROSSREF], [CSA]
  • Kramer G, Erdal H, Mertens H J, Nap M, Mauermann J, Steiner G, Marberger M, Biven K, Shoshan M C, Linder S. Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18. Cancer Res. 2004; 64(5)1751–1756, [INFOTRIEVE], [CROSSREF], [CSA]
  • Ueno T., Toi M., Biven K., Bando H., Ogava T., Linder S. Measurement of an apoptotic product in the sera of breast cancer patients. Eur J Cancer. 2003; 39(6)769–774, [INFOTRIEVE], [CROSSREF], [CSA]
  • Biven K., Erdal H., Hagg M., Ueno T., Zhou R., Lynch M., Rowley B., Wood J., Zhang C., Toi M., Shoshan M. C., Linder S. A novel assay for discovery and characterization of pro-apoptotic drugs and for monitoring apoptosis in patient sera. Apoptosis. 2003; 8(3)263–268, [INFOTRIEVE], [CROSSREF], [CSA]
  • Kerr J. F., Winterford C. M., Harmon B. V. Apoptosis. Its significance in cancer and cancer therapy. Cancer. 1994; 73(8)2013–2026, [CSA]
  • Wijsman J. H., Jonker R. R., Keijzer R., van de Velde C. J., Cornelisse C. J., van Dierendonck J. H. A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA. J Histochem Cytochem. 1993; 41(1)7–12, [INFOTRIEVE], [CSA]
  • Gavrieli Y., Sherman Y., Ben-Sasson S. A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 1992; 119(3)493–501, [INFOTRIEVE], [CROSSREF], [CSA]
  • Chiu P. M., Ngan Y. S., Khoo U. S., Cheung A. N. Apoptotic activity in gestational trophoblastic disease correlates with clinical outcome: assessment by the caspase-related M30 CytoDeath antibody. Histopathology. 2001; 38(3)243–249, [INFOTRIEVE], [CROSSREF], [CSA]
  • Archer C. D., Patron M., Smith I. E., Ellis P. A., Salter J., Ashley S., Gui G., Sacks N., Ebbs S. R., Allum W., Nasiri N., Dowsett M. Early changes in apoptosis and proliferation following primary chemotherapy for breast cancer. Br J Cancer. 2003; 89(6)1035–1041, [INFOTRIEVE], [CROSSREF], [CSA]
  • Buchholz T. A., Davis D. W., McConkey D. J., Symmans W. F., Valero V., Jhingran A., Tucker S. L., Pusztai L., Cristofanilli M., Esteva F. J., Hortobagyi G. N., Sahin A. A. Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy. Cancer J. 2003; 9(1)33–41, [INFOTRIEVE], [CSA]
  • Chang J., Ormerod M., Powles T. J., Allred D. C., Ashley S. E., Dowsett M. Apoptosis and proliferation as predictors of chemotherapy response in patients with breast carcinoma. Cancer. 2000; 89(11)2145–2152, [INFOTRIEVE], [CROSSREF], [CSA]
  • Davis D. W., Buchholz T. A., Hess K. R., Sahin A. A., Valero V., McConkey D. J. Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: early assessment predicts clinical response. Clin Cancer Res. 2003; 9(3)955–960, [INFOTRIEVE], [CSA]
  • Stearns V., Singh B., Tsangaris T., Crawford J. G., Novielli A., Ellis M. J., Isaacs C., Pennanen M., Tibery C., Farhad A., Slack R., Hayes D. F. A prospective randomized pilot study to evaluate predictors of response in serial core biopsies to single agent neoadjuvant doxorubicin or paclitaxel for patients with locally advanced breast cancer. Clin Cancer Res. 2003; 9(1)124–33, [INFOTRIEVE], [CSA]
  • Colleoni M., Minchella I., Mazzarol G., Nole F., Peruzzotti G., Rocca A., Viale G., Orlando L., Ferretti G., Curigliano G., Veronesi P., Intra M., Goldhirsch A. Response to primary chemotherapy in breast cancer patients with tumors not expressing estrogen and progesterone receptors. Ann Oncol. 2000; 11(8)1057–1059, [INFOTRIEVE], [CROSSREF], [CSA]
  • Colleoni M., Gelber S., Coates A. S., Castiglione-Gertsch M., Gelber R. D., Price K., Rudenstam C. M., Lindtner J., Collins J., Thurlimann B., Holmberg S. B., Cortes-Funes H., Simoncini E., Murray E., Fey M., Goldhirsch A., International Breast Cancer Study Group. Influence of endocrine-related factors on response to perioperative chemotherapy for patients with node-negative breast cancer. J Clin Oncol. 2001; 19(21)4141–4149, [INFOTRIEVE], [CSA]
  • MacGrogan G., Mauriac L., Durand M., Bonichon F., Trojani M., de Mascarel I., Coindre J. M. Primary chemotherapy in breast invasive carcinoma: predictive value of the immunohistochemical detection of hormonal receptors, p53, c-erbB-2, MiB1, pS2 and GST pi. Br J Cancer. 1996; 74(9)1458–1465, [INFOTRIEVE], [CSA]
  • Bonadonna G., Veronesi U., Brambilla C., Ferrari L., Luini A., Greco M., Bartoli C., Coopmans de Yoldi G., Zucali R., Rilke F. Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more. J Natl Cancer Inst. 1990; 82(19)1539–1545, [INFOTRIEVE], [CSA]
  • Lipponen P., Aaltomaa S., Kosma V. M., Syrjanen K. Apoptosis in breast cancer as related to histopathological characteristics and prognosis. Eur J Cancer. 1994; 30A(14)2068–2073, [INFOTRIEVE], [CROSSREF], [CSA]
  • Mustonen M., Raunio H., Paakko P., Soini Y. The extent of apoptosis is inversely associated with bcl-2 expression in premalignant and malignant breast lesions. Histopathology. 1997; 31(4)347–354, [INFOTRIEVE], [CROSSREF], [CSA]
  • Bear H. D., Anderson S., Smith R. E., Robidoux A., Kahlenberg M. S., Margolese R. G., Dakhil S. R., Pajon E. R., Hoehn J. L., Mamounas E. P., Geyer C. E., Julian T. B., Wolmark N. A randomized trial comparing preoperative (preop) doxorubicin/cyclophosphamide (AC) to preop AC followed by preop docetaxel (T) and to preop AC followed by postoperative (postop) T in patients (pts) with operable carcinoma of the breast: results of NSABP B-27. Breast Cancer Res. Treat. 2004; 88(2)16, (Abstr 26)[CSA]

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