Impact of sarcopenia on variceal rebleeding in patients after endoscopic therapy: a multicenter retrospective cohort study based on propensity score matching

References

• Albillos A, Tejedor M. Secondary prophylaxis for esophageal variceal bleeding. Clin Liver Dis. 2014;18(2):1–9. doi:10.1016/j.cld.2014.01.007.
   PubMed Web of Science ®Google Scholar
• de Franchis R, Baveno VI Faculty. Expanding consensus in portal hypertension: report of the baveno VI consensus workshop: stratifying risk and individualizing care for portal hypertension. J Hepatol. 2015;63(3):743–752. doi:10.1016/j.jhep.2015.05.022.
   PubMed Web of Science ®Google Scholar
• Garcia-Tsao G, Abraldes JG, Berzigotti A, et al. Portal hypertensive bleeding in cirrhosis: risk stratification, diagnosis, and management: 2016 practice guidance by the American association for the study of liver diseases. Hepatology. 2017;65(1):310–335. doi:10.1002/hep.28906.
   PubMed Web of Science ®Google Scholar
• Sheibani S, Khemichian S, Kim JJ, et al. Randomized trial of 1-week versus 2-week intervals for endoscopic ligation in the treatment of patients with esophageal variceal bleeding. Hepatology. 2016;64(2):549–555. doi:10.1002/hep.28597.
   PubMed Web of Science ®Google Scholar
• Xu L, Ji F, Xu QW, et al. Risk factors for predicting early variceal rebleeding after endoscopic variceal ligation. World J Gastroenterol. 2011;17(28):3347–3352. doi:10.3748/wjg.v17.i28.3347.
   PubMed Web of Science ®Google Scholar
• Tantai XX, Liu N, Yang LB, et al. Prognostic value of risk scoring systems for cirrhotic patients with variceal bleeding. World J Gastroenterol. 2019;25(45):6668–6680. doi:10.3748/wjg.v25.i45.6668.
   PubMed Web of Science ®Google Scholar
• Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(4):601–601. doi:10.1093/ageing/afz046.
   PubMed Web of Science ®Google Scholar
• Periyalwar P, Dasarathy S. Malnutrition in cirrhosis: contribution and consequences of sarcopenia on metabolic and clinical responses. Clin Liver Dis. 2012;16(1):95–131. doi:10.1016/j.cld.2011.12.009.
   PubMed Web of Science ®Google Scholar
• Paternostro R, Bardach C, Hofer BS, et al. Prognostic impact of sarcopenia in cirrhotic patients stratified by different severity of portal hypertension. Liver Int. 2021;41(4):799–809. doi:10.1111/liv.14758.
   PubMed Web of Science ®Google Scholar
• Lattanzi B, Gioia S, Di Cola S, et al. Prevalence and impact of sarcopenia in non-cirrhotic portal hypertension. Liver Int. 2019;39(10):1937–1942. doi:10.1111/liv.14160.
   PubMed Web of Science ®Google Scholar
• Zeng X, Shi ZW, Yu JJ, et al. Sarcopenia as a prognostic predictor of liver cirrhosis: a multicentre study in China. J Cachexia Sarcopenia Muscle. 2021;12(6):1948–1958. doi:10.1002/jcsm.12797.
   PubMed Web of Science ®Google Scholar
• Nardelli S, Lattanzi B, Merli M, et al. Muscle alterations are associated with minimal and overt hepatic encephalopathy in patients with liver cirrhosis. Hepatology. 2019;70(5):1704–1713. doi:10.1002/hep.30692.
   PubMed Web of Science ®Google Scholar
• Dajti E, Renzulli M, Ravaioli F, et al. The interplay between sarcopenia and portal hypertension predicts ascites and mortality in cirrhosis. Dig Liver Dis. 2023;55(5):637–643. doi:10.1016/j.dld.2022.11.011.
   PubMedGoogle Scholar
• Hwang JH, Shergill AK, Acosta RD, et al. The role of endoscopy in the management of variceal hemorrhage. Gastrointest Endosc. 2014;80(2):221–227. doi:10.1016/j.gie.2013.07.023.
   PubMed Web of Science ®Google Scholar
• Bunchorntavakul C, Reddy KR. Review article: malnutrition/sarcopenia and frailty in patients with cirrhosis. Aliment Pharmacol Ther. 2020;51(1):64–77. doi:10.1111/apt.15571.
   PubMed Web of Science ®Google Scholar
• Montano-Loza AJ, Duarte-Rojo A, Meza-Junco J, et al. Inclusion of sarcopenia within MELD (MELD-Sarcopenia) and the prediction of mortality in patients with cirrhosis. Clin Transl Gastroenterol. 2015;6(7):e102. doi:10.1038/ctg.2015.31.
   PubMedGoogle Scholar
• Rodrigues SG, Brabandt B, Stirnimann G, et al. Adipopenia correlates with higher portal pressure in patients with cirrhosis. Liver Int. 2019;39(9):1672–1681. doi:10.1111/liv.14175.
   PubMed Web of Science ®Google Scholar
• Tandon P, Montano-Loza AJ, Lai JC, et al. Sarcopenia and frailty in decompensated cirrhosis. J Hepatol. 2021;75(Suppl 1):S147–s162. doi:10.1016/j.jhep.2021.01.025.
   PubMed Web of Science ®Google Scholar
• Benmassaoud A, Roccarina D, Arico F, et al. Sarcopenia does not worsen survival in patients with cirrhosis undergoing transjugular intrahepatic portosystemic shunt for refractory ascites. Am J Gastroenterol. 2020;115(11):1911–1914. doi:10.14309/ajg.0000000000000959.
   PubMed Web of Science ®Google Scholar
• Ebadi M, Bhanji RA, Tandon P, et al. Review article: prognostic significance of body composition abnormalities in patients with cirrhosis. Aliment Pharmacol Ther. 2020;52(4):600–618. doi:10.1111/apt.15927.
   PubMed Web of Science ®Google Scholar
• Casati M, Costa AS, Capitanio D, et al. The biological foundations of sarcopenia: established and promising markers. Front Med (Lausanne). 2019;6:184. doi:10.3389/fmed.2019.00184.
   PubMed Web of Science ®Google Scholar
• Triantos C, Kalafateli M, Assimakopoulos SF, et al. Endotoxin translocation and gut barrier dysfunction are related to variceal bleeding in patients with liver cirrhosis. Front Med (Lausanne). 2022;9:836306. doi:10.3389/fmed.2022.836306.
   PubMed Web of Science ®Google Scholar
• Traub J, Reiss L, Aliwa B, et al. Malnutrition in patients with liver cirrhosis. Nutrients. 2021;13(2):13. doi:10.3390/nu13020540.
   Web of Science ®Google Scholar
• Meyer F, Bannert K, Wiese M, et al. Molecular mechanism contributing to malnutrition and sarcopenia in patients with liver cirrhosis. Int J Mol Sci. 2020;21(15):21.
   Web of Science ®Google Scholar
• Møller S, Bendtsen F, Christensen E, et al. Prognostic variables in patients with cirrhosis and oesophageal varices without prior bleeding. J Hepatol. 1994;21(6):940–946. doi:10.1016/s0168-8278(05)80599-9.
   PubMed Web of Science ®Google Scholar
• Sakai Y, Iwata Y, Enomoto H, et al. Two randomized controlled studies comparing the nutritional benefits of branched-chain amino acid (BCAA) granules and a BCAA-enriched nutrient mixture for patients with esophageal varices after endoscopic treatment. J Gastroenterol. 2015;50(1):109–118. doi:10.1007/s00535-014-0950-2.
   PubMed Web of Science ®Google Scholar
• Wang R, Huang X, Zhou T, et al. Safety and feasibility of early oral nutrition after endoscopic treatment for patients with liver cirrhosis: a historical prospective and comparative effectiveness study. JPEN J Parenter Enteral Nutr. 2022;46(7):1660–1670. doi:10.1002/jpen.2328.
   PubMed Web of Science ®Google Scholar
• Levy A, Fraser D, Rosen SD, et al. Anemia as a risk factor for infectious diseases in infants and toddlers: results from a prospective study. Eur J Epidemiol. 2005;20(3):277–284. doi:10.1007/s10654-004-6515-6.
   PubMed Web of Science ®Google Scholar
• Hou MC, Lin HC, Liu TT, et al. Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: a randomized trial. Hepatology. 2004;39(3):746–753. doi:10.1002/hep.20126.
   PubMed Web of Science ®Google Scholar
• Albillos A, Zamora J, Martínez J, et al. Stratifying risk in the prevention of recurrent variceal hemorrhage: results of an individual patient meta-analysis. Hepatology. 2017;66(4):1219–1231. doi:10.1002/hep.29267.
   PubMed Web of Science ®Google Scholar
• Pfisterer N, Dexheimer C, Fuchs EM, et al. Betablockers do not increase efficacy of band ligation in primary prophylaxis but they improve survival in secondary prophylaxis of variceal bleeding. Aliment Pharmacol Ther. 2018;47(7):966–979. doi:10.1111/apt.14485.
   PubMed Web of Science ®Google Scholar
• Trebicka J, Gu W, Ibáñez-Samaniego L, et al. Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS. J Hepatol. 2020;73(5):1082–1091. doi:10.1016/j.jhep.2020.04.024.
   PubMed Web of Science ®Google Scholar