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Original Paper

The Effect of Various Inulins and Clostridium difficile on the Metabolic Activity of the Human Colonic Microbiota in vitro

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Pages 137-144 | Received 25 Apr 2003, Accepted 17 Sep 2003, Published online: 11 Jul 2009

REFERENCES

  • Vijn I, Smeekens S. Fructan: more than a reserve carbohydrate? Plant Physiol 1999; 120: 352–9.
  • van Loo JAE, Coussement P, de Leenheer L, Hoebregs H, Smits G. On the presence of inulin and oligofructose as natural ingredients in the western diet. Crit Rev Food Sci Nutr 1995; 35: 525–52.
  • Boeckner LS, Schnepf MI, Tungland BC. Inulin: a review of nutritional and heath implications. Adv Food Nutr Rev 2001; 43: 1–63.
  • Hirayama F, Hikada H. Production and utilization of micro-bial fructans. In: Suzuki M, Chatterton NJ, eds. Science and Technology of Fructans. Boca Raton, FL: CRC Press, 1993: 274–302.
  • Roberfroid MB. Caloric value of inulin and oligofructose. J Nutr 1999; 129: 1436s–7.
  • Gibson GR, Beatty ER, Wang X, Cummings JH. Selective stimulation of bifidobacteria in the human colon by oligofruc-tose and inulin. Gastroenterology 1995; 108: 975–82.
  • Kruse H-P, Kleesen B, Blaut M. Effect of inulin on faecal bifidobacteria in human subjects. Br J Nutr 1999; 82: 375–82.
  • Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 1995; 125: 1401–12.
  • Wang X, Gibson GR. Effects of the in vitro fermentation of oligofructose and inulin by bacteria growing in the human large intestine. J Appl Bacteriol 1993; 75: 373–80.
  • Flamm G, Glinsmann W, Kritchevsky D, Prosky L, Roberfroid M. Inulin and oligofructose as dietary fiber: a review of the evidence. Crit Rev Food Science Nutr 2001; 41: 353–62.
  • MacFarlane GT. Fermentation reactions in the large intestine. In: Roche AF, ed. Short-chain fatty acids: metabolism and clinical importance. Report of the Tenth Ross Conference on Medical Research. Columbus, OH: Ross Laboratories, 1991: 5–10.
  • Mortensen PB, Clausen MR. Short-chain fatty acids in the human colon: relation to gastrointestinal health and disease. Scand J Gastroenterol 1996; 16: 132–48.
  • Rowland IR. Toxicology of the colon: role of the intestinal microbiota. In: Gibson GR, MacFarlane GT, eds. Human Colonic Bacteria: Role in Nutrition, Physiology and Pathology. London: CRC Press, 1995: 155–74.
  • MacFarlane S, MacFarlane GT. Proteolysis and amino acid fermentation. In: Gibson GR, MacFarlane GT, eds. Human Colonic Bacteria: Role in Nutrition, Physiology and Pathology. London: CRC Press, 1995: 75–100.
  • Hambley RJ, Rumney CJ, Fletcher JM, Rijken PJ, Rowland IR. Effect of high- and low-risk diets on gut microflora-associated biomarkers of colon cancer in human flora-asso-ciated rats. Nutr Cancer 1997; 27: 250–5.
  • Clinton SK. Dietary protein and carcinogenesis. In: Rowland IR, ed. Nutrition, Toxicity and Cancer. Boca Raton, FL: CRC Press, 1992: 455–79.
  • Matsui T, Matsukawa Y, Sakai T, Nakamura T, Aoike A, Kawai K. Effect of ammonia on cell-cycle progression of human gastric cancer cells. Eur J Gastroenterol Hepatol 1995; 7: S79–81.
  • Chaplin MF. Bile acids, fibre and colon cancer: the story unfolds. J R Soc Health 1998; 118: 53–61.
  • Sartor RB. Probiotics in chronic pouchitis: restoring luminal microbial balance. Gastroenterology 2000; 119: 584–7.
  • Spencer RC. The role of antimicrobial agents in the aetiology of Clostridium diffici/e -associated disease. J Antimicrob Che-mother 1998; 41: 21–7.
  • Kelly CP, Pathoulakis C, LaMont JT. Clostridium difficile colitis. N Engl J Med 1994; 330: 257–62.
  • Gibson GR, Cummings JH, MacFarlane GT. Use of a three-stage continuous culture system to study the effect of mucin on dissimilatory sulphate reduction and methanogenesis by mixed populations of human gut bacteria. Appl Environ Microbiol 1998; 54: 2750–5.
  • Minekus M, Smeets-Peeters M, Bemalier A, Marol-Bonnin S, Havenaar R, Marteau P, Alric M, Fonty G, Huis in't Veld JH. A computer-controlled system to simulate conditions of the large intestine with peristaltic mixing, water absorption and absorption of fermentation products. Appl Microbiol Biotech-nol 1999; 53: 108–14.
  • Venema K, van Nuenen HMC, Smeets-Peeters M, Minekus M, Havenaar R. TNO's in vitro large intestinal model: an excellent screening tool for functional food and pharmaceutical research. Emährung/Nutrition 2000; 24: 558–64.
  • Jouany JP. Volatile fatty acids and alcohols determination in digestive contents, silage juice, bacterial culture and anaerobic fermenter contents. Sci Aliments 1982; 2: 131–44.
  • Smith EA, MacFarlane GT. Formation of phenolic and indolic compounds by anaerobic bacteria in the human large intestine. Microb Ecol 1997; 33: 180–8.
  • Jensen MT, Jensen BB. Gas chromatographic determination of indole and 3-methylindole (skatole) in bacterial culture media, intestinal contents and faeces. J Chromatogr B 1994; 655: 275–80.
  • Levrat MA, Rémésy C, Demigné C. Influence of inulin on urea and ammonia nitrogen fluxes in the rat cecum: consequences on nitrogen excretion. J Nutr Biochem 1993; 4: 351–6.
  • Bomet F. Fructo-oligosaccharides and other fructans: chem-istry, structure and nutritional effects. In: McCleary BY, Prosky L, eds. Advanced Dietary Fibre Technology. Oxford: Blackwell Science, 2001: 480–93.
  • May T, Mackie RI, Fahey GC, Cremin JC, Garleb KA. Effect of fiber source on short-chain fatty acid production and on the growth and toxin production by Clostridium difficile. Scand J Gastroenterol 1994; 19: 916–22.
  • Terada EA, Hara H, Kataoka M, Misuoka T. Effect of lactulose on the composition and metabolic activity of the human faecal flora. Microb Ecol Health Disease 1992; 5: 43–50.
  • Hidaka H, Tashiro Y, Eida T. Proliferation of Bifidobacteria by oligosaccharides and their useful effect on human health. Bifidobacteria Microflora 1991; 10: 65–79.
  • Bemalier A, Doré J, Durand M. Biochemistry of fermentation. In: Gibson MR, Roberfroid MB, eds. Colonic Microbiota, Nutrition and Health. Dordrecht: Kluwer Academic Publish-ers, 1999: 37–53.
  • Kleessen B, Sykura B, Zunft H-J, Blaut M. Effect of inulin and lactose on fecal microliora, microbial activity, and bowel habit in elderly constipated persons. Am J Clin Nutr 1997; 65: 1397–402.
  • Alles MS, Hartemink R, Meyboom S, Harryvan JL, Van Laere KM, Nagengast FM, Hautvast JG. Effect of transgalactooli-gosaccharides on the composition of the human intestinal microliora and on putative risk markers for colon cancer. Am J Clin Nutr 1999; 69: 980–91.