Endocrine Pancreas Histology of Congenic BB-Rat Strains with Reduced Diabetes Incidence After Genetic Manipulation on Chromosomes 4, 6 and X

References

• Knifing, I. and Vogt, L. (1991) "BB/0(ttawa)K(arlsburg) rats: features of a sublime of diabetes-prone BB rats", Diabetes Res. 18, 79–87.
   PubMedGoogle Scholar
• Homum, L., Romer, J. and Markholst, H. (2002) "The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddml", Diabetes 51, 1972–1979.
   PubMed Web of Science ®Google Scholar
• MacMurray, A.J., Moralejo, D.H., Kwitek, A.E., Rutledge, E.A., Van Yserloo, B., Gohlke, P., et al. (2002) "Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene", Genome Res. 12, 1029–1039.
   PubMed Web of Science ®Google Scholar
• Knifing, I., van den Brandt, J. and Kuttler, B. (2001) "Genes of SHR rats protect spontaneously diabetic BB/OK rats from diabetes: lessons from congenic BB.SHR rat strains", Biochem. Biophys. Res. Commun. 283, 399–405.
   PubMed Web of Science ®Google Scholar
• Van den Brandt, J., Kovacs, P. and Kliiting, I. (1999) "Congenic diabetes-prone BB.Sa and BB.Xs rats differ from their progenitor strain BB/OK in frequency and severity of insulin-dependent diabetes mellitus", Biochem. Biophys. Res. Commun. 263, 843–847.
   PubMed Web of Science ®Google Scholar
• Knifing, I., Kovacs, P. and Kuttler, B. (1997) "Phenotypic consequences after restoration of lymphopenia in the diabetes-prone BB/OK rat", Biochem. Biophys. Res. Commun. 239, 106–110.
   PubMed Web of Science ®Google Scholar
• Knifing, I., Voigt, B. and Kovacs, P. (1998) "Metabolic features of newly established diabetes-prone BB.SHR rat strains", Life Sci. 62, 973–979.
   PubMed Web of Science ®Google Scholar
• Witt, S., Dietz, H., Ziegler, B., Keilacker, H. and Ziegler, M. (1988) "Production and use of monoclonal glucagon and insulin antibodies-reduction of pancreatic insulin in rats by treatment with complete Freund's adjuvant", Acta Histochem. 35(Suppl.), 217–223.
   Google Scholar
• Hahn, H.J., Lucke, S., Knifing, I. and Besch, W. (1991) "Prospective investigations of long-term normoglycaemic BB/OK-rats: serialdetermination of glucose tolerance, insulitis, B-cell volume density and pancreatic insulin content", Exp. Clin. Endocrinol. 98, 185 —192.
   Google Scholar
• Denk, H. (1989) "Immunhistochemische Färbemethoden", In: Böck, P., ed, Mikroskopische Technik (Urban and Schwarzen-berg, Mtinchen—Wien—Baltimore) pp. 251–261.
   Google Scholar
• Cordell, J.L., Falini, B., Erber, W.N., Ghosh, A.K., Abdulaziz, Z., MacDonald, S., Pulford, K.A., Stein, H. and Mason, D.Y. (1984) "Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes)", J. Histochem. Cyto-chem. 32, 219–229.
   Google Scholar
• Weibel, E.R. (1969) "Stereological principles for morphometry in electron microscopic cytology", Int. Rev. Cytol. 26, 235–302.
   PubMedGoogle Scholar
• Lucke, S., Ziegler, B., Diaz-Alonso, J.M. and Hahn, H.J. (1985) "Eignung spezifischer Färbemethoden fiir die Bestimmung des 13-Zellvolumens im Rattenpankreas mit normalem und reduziertem Insulingehalt", Acta Histochem. 77, 107–116.
   PubMed Web of Science ®Google Scholar
• Ziegler, B., Hahn, H.J. and Ziegler, M. (1985) "Insulin recovery in pancreas and host organs of islet grafts", Exp. Clin. Endocrinol. 85, 53–60.
   PubMedGoogle Scholar
• Knifing, I., Stark, 0. and Fischer, U. (1988) "Incidence of diabetes in F2 and first backcross hybrids of BB rats of different origin", In: Shafrir, R., ed, Lessons from animal diabetes II (J. Libbey, London, Paris) pp. 85–87.
   Google Scholar
• Knifing, I. and Vogt, L. (1990) "Coat colour phenotype, leucopenia and insulin-dependent diabetes mellitus in BB rats", Diabetes Res. 15, 37–39.
   PubMedGoogle Scholar
• Knifing, I., Vogt, L. and Serikawa, T. (1995) "Locus on chromosome 18 cosegregates with diabetes in the BB/OK rat sublime", Diabet. Metab. 21, 338–344.
   Google Scholar
• Knifing, I. and Kovacs, P. (1998) "Crosses between diabetic BB/OK and wild rats confirm that a 3rd gene is essential for diabetes development", Acta Diabetol. 35, 109–111.
   PubMed Web of Science ®Google Scholar
• Knifing, I., Schmidt, S. and Kovacs, P. (1998) "Mapping of novel diabetes predisposing and protecting genes in the spontaneously diabetic BB/OK rat", Biochem. Biophys. Res. Commun. 245, 483–486.
   PubMed Web of Science ®Google Scholar
• Knifing, I. and Kovacs, P. (1998) "Genes of the immune system co segregate with the age at onset of diabetes in the BB/OK rat", Biochem. Biophys. Res. Commun. 242, 461–463.
   PubMed Web of Science ®Google Scholar
• Knifing, I. and Kovacs, P. (1998) "Phenotypic differences between diabetes-prone BB rat sublines cosegregate with loci on chromosomes X and 10", Biochem. Mol. Biol. Int. 45, 865–870.
   PubMedGoogle Scholar
• Hahn, H.J., Lucke, S., Knifing, I., Volk, H.D., Baehr, R.V. and Diamantstein, T. (1987) "Curing BB rats of freshly manifested diabetes by short-term treatment with a combination of a monoclonal anti-interleukin 2 receptor antibody and a subthera-peutic dose of cyclosporin A", Eur J. Immunol. 17, 1075–1080.
   PubMed Web of Science ®Google Scholar
• Lucke, S., Besch, W., Kauert, C. and Hahn, H.J. (1988) "The endocrine pancreas of BB/OK-rats before and at diagnosis of hyperglycaemia", Exp. Clin. Endocrinol. 91, 161–170.
   PubMedGoogle Scholar
• Hahn, H.J., Lucke, S., Knifing, I. and Besch, W. (1991) "Prospective investigations of long-term normoglycaemic BB/OK-rats: serial determination of glucose tolerance, insulitis, B-cell volume density and pancreatic insulin content", Exp. Clin. Endocrinol. 98, 185 —192.
   Google Scholar
• Kuttler, B., Kauert, C., Wanka, H., Diamantstein, T. and Hahn, H.J. (1996) "Temporary anti-CD25/CsA therapy induces a CD4+ T-cell-mediated tolerance in BB/OK rats", J. Autoimmun. 9, 321 —329.
   Web of Science ®Google Scholar
• Hahn, H.J., Ziegler, B. and Lucke, S. (1989) "Streptozotocin-diabetic BB/OK rats accept permanently BB/OK-islet grafts without inununosuppression", Z Versuchstierkd. 32(3), 135 —140.
   Google Scholar
• Foglia, V.G. (1944) "Characteristicas de la diabetes en la rata", Rev. Soc. Argent. Biol. 20, 21 —31.
   Google Scholar
• Martin, T.M. and Lacy, P.E. (1963) "The prediabetic period in partially pancreatectomized rats", Diabetes 12, 238–242.
   Web of Science ®Google Scholar
• Pack, C.D., Cestra, A.E., Min, B., Legge, K.L., Li, L., Caprio-Young, J.C., Bell, J.J., Gregg, R.K. and Zaghouani, H. (2001) "Neonatal exposure to antigen primes the immune system to develop responses in various lymphoid organs and promotes bystander regulation of diverse T cell specificities", J. Immunol. 167, 4187–4195.
   PubMed Web of Science ®Google Scholar
• Bach, J.F. and Chatenoud, L. (2001) "Tolerance to islet autoantigens in type 1 diabetes", Ann. Rev. Immunol. 19, 131–161.
   PubMed Web of Science ®Google Scholar
• Sobel, DO., Azumi, N., Creswell, K., Holterman, D., Blair, 0.C., Bellanti, J.A., Abbassi, V. and Hiserodt, J.C. (1995) "The role of NK cell activity in the pathogenesis of poly I:C accelerated and spontaneous diabetes in the diabetes prone BB rat", J. Autoimmun. 8, 843–857.
   PubMed Web of Science ®Google Scholar
• Sobel, DO., Newsome, J., Ewel, C.H., Bellanti, J.A., Abbassi, V., Creswell, K. and Blair, 0. (1992) "Poly I:C induces development of diabetes mellitus in BB rat", Diabetes 41, 515–520.
   Google Scholar
• Sobel, DO., Goyal, D., Ahvazi, B., Yoon, J.W., Chung, Y.H., Bagg, A. and Harlan, D.M. (1998) "Low dose poly I:C prevents diabetes in the diabetes prone BB rat", J. Autoimmun. 11, 343–352.
   PubMed Web of Science ®Google Scholar
• Kolb, H., Zielasek, J., Treichel, U., Freytag, G., Wrann, M. and Kiesel, U. (1986) "Recombinant interleukin 2 enhances spon-taneous insulin-dependent diabetes in BB rats", Ear. J. Immunol. 16, 209–212.
   PubMed Web of Science ®Google Scholar
• Zielasek, J., Burkart, V., Naylor, P., Goldstein, A., Kiesel, U. and Kolb, H. (1990) "Interleukin-2-dependent control of disease development in spontaneously diabetic BB rats", Immunology 69, 209–214.
   PubMed Web of Science ®Google Scholar