Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4

References

• Chapman D, Perry G, Strine T. The vital link between chronic disease and depressive disorders. Prev Chronic Dis. 2008;2(1):A14.
   Google Scholar
• Black CN, Bot M, Scheffer PG, et al. Is depression associated with increased oxidative stress? A systematic review and meta-analysis. Psychoneuroendocrinology. 2015;51:164–175.
   PubMed Web of Science ®Google Scholar
• Mohebbi M, Agustini B, Woods RL, et al. Prevalence of depressive symptoms and its associated factors among healthy community-dwelling older adults living in Australia and the United States. Int J Geriatr Psychiatry. 2019;34(8):1208–1216.
   PubMed Web of Science ®Google Scholar
• Elhadidy ME, Salama AA, El-Kassaby M, et al. Protective effect of Hypericum perforatum on dexamethasone-induced diabetic depression in rats. J Arab Soc Med Res. 2019;14(1):25.
   Google Scholar
• Das UN. Is depression a low-grade systemic inflammatory condition? Am J Clin Nutr. 2007;85(6):1665–1666.
   PubMed Web of Science ®Google Scholar
• Liu Q, He H, Yang J, et al. Changes in the global burden of depression from 1990 to 2017: findings from the Global Burden of Disease study. J Psychiatr Res. 2020;126:134–140.
   PubMed Web of Science ®Google Scholar
• Odejimi O, Tadros G, Sabry N. A systematic review of the prevalence of mental and neurocognitive disorders amongst older adults’ populace in Egypt. Middle East Curr Psychiatry. 2020;27(1):1–12.
   Google Scholar
• Bueno-Notivol J, Gracia-García P, Olaya B, et al. Prevalence of depression during the COVID-19 outbreak: a meta-analysis of community-based studies. Int J Clin Health Psychol. 2021;21(1):100196.
   PubMed Web of Science ®Google Scholar
• Shaki F, Ashari S, Ahangar N. Melatonin can attenuate ciprofloxacin induced nephrotoxicity: involvement of nitric oxide and TNF-α. Biomed Pharmacother. 2016;84:1172–1178.
   PubMed Web of Science ®Google Scholar
• Rawi SM, Alshibly NM, El-Nasr FS. Neurotoxic effect of ciprofloxacin on albino rat. J Appl Pharm. 2014;6:121–132.
   Google Scholar
• Rawi SM, Mourad IM, Arafa NM, et al. Effect of ciprofloxacin and levofloxacin on some oxidative stress parameters in brain regions of male albino rats. Afr J Pharm Pharmacol. 2011;5:1888–1897.
   Google Scholar
• Kamath A, Jan-Mar R. Fluoroquinolone induced neurotoxicity: a review. J Adv Pharm Educ Res. 2013;3:72–75.
   Google Scholar
• Ma Q. Role of Nrf2 in oxidative stress and toxicity. Annu Rev Pharmacol Toxicol. 2013;53:401–426.
   PubMed Web of Science ®Google Scholar
• Talalay P, Dinkova-Kostova AT, Holtzclaw WD. Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis. Adv Enzyme Regul. 2003;43:121–134.
   PubMedGoogle Scholar
• Das UN. Vagus nerve stimulation, depression, and inflammation. Neuropsychopharmacology. 2007;32(9):2053–2054.
   PubMed Web of Science ®Google Scholar
• Singhal G, Jaehne EJ, Corrigan F, et al. Inflammasomes in neuroinflammation and changes in brain function: a focused review. Front Neurosci. 2014;8:315.
   PubMed Web of Science ®Google Scholar
• Silva-Filho SE, de Souza Silva-Comar FM, Wiirzler LAM, et al. Effect of camphor on the behavior of leukocytes in vitro and in vivo in acute inflammatory response. Trop J Pharm Res. 2015;13(12):2031–2037.
   Web of Science ®Google Scholar
• Lee HJ, Hyun E-A, Yoon WJ, et al. In vitro anti-inflammatory and anti-oxidative effects of Cinnamomum camphora extracts. J Ethnopharmacol. 2006;103(2):208–216.
   PubMed Web of Science ®Google Scholar
• Singh GK, Rai G, Chatterjee SS, et al. Beneficial effects of Fumaria indica on chronic stress-induced neurobehavioral and biochemical perturbations in rats. Chin Med. 2012;3:49–60.
   Google Scholar
• Shata FY, Eldebaky H, Abd El Hameed AR. Effects of camphor on hepatic enzymes, steroids and antioxidant capacity of male rats intoxicated with atrazine. Middle-East J Sci Res. 2014;22:553–560.
   Google Scholar
• Hamidpour R, Hamidpour S, Hamidpour M, et al. Camphor (Cinnamomum camphora), a traditional remedy with the history of treating several diseases. Int J Case Rep Images. 2013;4(2):86–89.
   Google Scholar
• Aryanezhad M, Abdi M, Amini S, et al. Cinnamomum zeylanicum extract has antidepressant-like effects by increasing brain-derived neurotrophic factor (BDNF) and its receptor in prefrontal cortex of rats. Avicenna J Phytomed. 2020. In press.
   Google Scholar
• Ilgin S, Can OD, Atli O, et al. Ciprofloxacin-induced neurotoxicity: evaluation of possible underlying mechanisms. Toxicol Mech Methods. 2015;25(5):374–381.
   PubMed Web of Science ®Google Scholar
• Shahabi S, Jorsaraei SG, Akbar Moghadamnia A, et al. The effect of camphor on sex hormones levels in rats. Cell J. 2014;16:231–234.
   PubMed Web of Science ®Google Scholar
• Kamel R, Salama A, Shaffie NM, et al. Cerebral effect of optimized Allium sativum oil-loaded chitosan nanorods: GC–MS analysis and in vitro/in vivo evaluation. Food Funct. 2020;11(6):5357–5376.
   PubMed Web of Science ®Google Scholar
• Salama AA, Ibrahim BM. Neurotherapeutic effect of allopurinol against brain injury in hyperlipidemic rats. Afr J Pharm Pharmacol. 2015;9:567–575.
   Google Scholar
• Vijitruth R, Liu M, Choi DY, et al. Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease. J Neuroinflamm. 2006;3:6.
   PubMed Web of Science ®Google Scholar
• Salama AH, Elmotasem H, Salama AA. Nanotechnology based blended chitosan–pectin hybrid for safe and efficient consolidative antiemetic and neuro-protective effect of meclizine hydrochloride in chemotherapy induced emesis. Int J Pharm. 2020;584:119411.
   PubMedGoogle Scholar
• Salama A, Hegazy R, Hassan A. Intranasal chromium induces acute brain and lung injuries in rats: assessment of different potential hazardous effects of environmental and occupational exposure to chromium and introduction of a novel pharmacological and toxicological animal model. PLoS One. 2016;11(12):e0168688.
   PubMed Web of Science ®Google Scholar
• Strickland PL, Deakin JW, Percival C, et al. Bio-social origins of depression in the community. Interactions between social adversity, cortisol and serotonin neurotransmission. Br J Psychiatry. 2002;180:168–173.
   PubMed Web of Science ®Google Scholar
• Brown A, Gershon S. Dopamine and depression. J Neural Transm Gen Sect. 1993;91(2–3):75–109.
   PubMed Web of Science ®Google Scholar
• Yang W, Shen Z, Wen S, et al. Mechanisms of multiple neurotransmitters in the effects of lycopene on brain injury induced by hyperlipidemia. Lipids Health. 2018;17:1–13.
   PubMed Web of Science ®Google Scholar
• Harlow E, Lane D. Using antibodies: a laboratory manual. Plainview (NY): Cold Spring Harbor Laboratory Press; 1999. p. 352–355.
   Google Scholar
• Kessler RC, Berglund P, Demler O, et al. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62(6):593–602.
   PubMed Web of Science ®Google Scholar
• Rabadia J, Satish S, Ramanjaneyulu J, et al. An investigation of anti-depressant activity of Cinnamomum camphora oil in experimental mice. Asian J Biomed. 2013;3:44.
   Google Scholar
• Porsolt RD, Anton G, Blavet N, et al. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol. 1978;47(4):379–391.
   PubMed Web of Science ®Google Scholar
• Kandasamy R, Calsbeek JJ, Morgan MM. Analysis of inflammation-induced depression of home cage wheel running in rats reveals the difference between opioid antinociception and restoration of function. Behav Brain Res. 2017;317:502–507.
   PubMed Web of Science ®Google Scholar
• Gilli F, Royce DB, Pachner AR. Measuring progressive neurological disability in a mouse model of multiple sclerosis. J Vis Exp. 2016.
   Google Scholar
• Żmudzka E, Sałaciak K, Sapa J, et al. Serotonin receptors in depression and anxiety: insights from animal studies. Life Sci. 2018;210:106–124.
   PubMed Web of Science ®Google Scholar
• Nautiyal KM, Hen R. Serotonin receptors in depression: from A to B. F1000Res. 2017;6:123.
   PubMedGoogle Scholar
• Dremencov E, Newman ME, Kinor N, et al. Hyperfunctionality of serotonin-2C receptor-mediated inhibition of accumbal dopamine release in an animal model of depression is reversed by antidepressant treatment. Neuropharmacology. 2005;48(1):34–42.
   PubMed Web of Science ®Google Scholar
• Shirayama Y, Chaki S. Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents. Curr Neuropharmacol. 2006;4(4):277–291.
   PubMed Web of Science ®Google Scholar
• van Diermen D, Marston A, Bravo J, et al. Monoamine oxidase inhibition by Rhodiola rosea L. roots. J Ethnopharmacol. 2009;122(2):397–401.
   PubMed Web of Science ®Google Scholar
• Gürbay A, Hincal F. Ciprofloxacin-induced glutathione redox status alterations in rat tissues. Drug Chem Toxicol. 2004;27(3):233–242.
   PubMed Web of Science ®Google Scholar
• Bulut M, Selek S, Gergerlioglu HS, et al. Malondialdehyde levels in adult attention-deficit hyperactivity disorder. J Psychiatry Neurosci. 2007;32:435.
   PubMed Web of Science ®Google Scholar
• Rybka J, Kędziora-Kornatowska K, Banaś-Leżańska P, et al. Interplay between the pro-oxidant and antioxidant systems and proinflammatory cytokine levels, in relation to iron metabolism and the erythron in depression. Free Radic Biol Med. 2013;63:187–194.
   PubMed Web of Science ®Google Scholar
• Qin P, Liu R. Oxidative stress response of two fluoroquinolones with catalase and erythrocytes: a combined molecular and cellular study. J Hazard Mater. 2013;252–253:321–329.
   PubMed Web of Science ®Google Scholar
• Somade OT, Adeniji KD, Adesina A-RA, et al. Oral acute toxicity study as well as tissues oxidative stress and histopathological disorders in edible camphor administered rats. Exp Toxicol Pathol. 2017;69(2):99–108.
   PubMedGoogle Scholar
• Abass MA, Elkhateeb SA, Abd El-Baset SA, et al. Lycopene ameliorates atrazine-induced oxidative damage in adrenal cortex of male rats by activation of the Nrf2/HO-1 pathway. Environ Sci Pollut Res Int. 2016;23(15):15262–15274.
   PubMed Web of Science ®Google Scholar
• Slavich GM, Irwin MR. From stress to inflammation and major depressive disorder: a social signal transduction theory of depression. Psychol Bull. 2014;140(3):774–815.
   PubMed Web of Science ®Google Scholar
• Dunn AJ, Swiergiel AH, de Beaurepaire R. Cytokines as mediators of depression: what can we learn from animal studies? Neurosci Biobehav Rev. 2005;29(4–5):891–909.
   PubMed Web of Science ®Google Scholar
• Jiang J, Shen YY, Li J, et al. (+)-Borneol alleviates mechanical hyperalgesia in models of chronic inflammatory and neuropathic pain in mice. Eur J Pharmacol. 2015;757:53–58.
   PubMed Web of Science ®Google Scholar
• Kuzmich NN, Sivak KV, Chubarev VN, et al. TLR4 signaling pathway modulators as potential therapeutics in inflammation and sepsis. Vaccines (Basel). 2017;5(4):34.
   PubMed Web of Science ®Google Scholar
• Rogero MM, Calder PC. Obesity, inflammation, toll-like receptor 4 and fatty acids. Nutrients. 2018;10(4):432.
   PubMed Web of Science ®Google Scholar
• Miller AH. Mechanisms of cytokine-induced behavioral changes: psychoneuroimmunology at the translational interface Norman Cousins Lecture. Brain Behav Immun. 2009;23(2):149–158.
   PubMed Web of Science ®Google Scholar
• Zhao L, Lee JY, Hwang DH. Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals. Nutr Rev. 2011;69(6):310–320.
   PubMed Web of Science ®Google Scholar
• Mulloy JC, Cancelas JA, Filippi M-D, et al. Rho GTPases in hematopoiesis and hemopathies. Blood. 2010;115(5):936–947.
   PubMed Web of Science ®Google Scholar
• Billuart P, Winter CG, Maresh A, et al. Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway. Cell. 2001;107(2):195–207.
   PubMed Web of Science ®Google Scholar
• Brouns MR, Matheson SF, Settleman J. p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001;3(4):361–367.
   PubMed Web of Science ®Google Scholar