Differences in LPS and PepG Induced Release of Inflammatory Cytokines in Orthopedic Trauma

REFERENCES

• Rotstein O D. Modeling the two-hit hypothesis for evaluating strategies to prevent organ injury after shock/resuscitation. J Trauma 2003; 54(Suppl.)S203–S206
   PubMedGoogle Scholar
• Dinarello C A. Proinflammatory cytokines. Chest 2000; 118: 503–508
   PubMed Web of Science ®Google Scholar
• Hotchkiss R S, Karl I E. The pathophysiology and treatment of sepsis. N Engl J Med 2003; 348: 138–150
   PubMed Web of Science ®Google Scholar
• Hietbrink F, Koenderman L, Rijkers G, et al. Trauma: the role of the innate immune system. World J Emerg Surg 2006; 20: 1–15
   Google Scholar
• DeLong W G, Born C T. Cytokines in patients with polytrauma. Clin Orthop Rel Res 2004; 422: 57–65
   Google Scholar
• Tomic V, Russwurm S, Moller E, et al. Transcriptomic and proteomic patterns of systemic inflammation in on-pump and off-pump coronary artery bypass grafting. Circulation 2005; 112: 2912–2920
   PubMed Web of Science ®Google Scholar
• Keel M, Trentz O. Pathophysiology of polytrauma. Injury 2005; 36: 691–709
   PubMed Web of Science ®Google Scholar
• Bone R C. Sir Isaac Newton, sepsis, SIRS, and CARS. Crit Care Med 1996; 24: 1125–1128
   PubMed Web of Science ®Google Scholar
• Dimofte G, Alexander A, Carlson G, et al. TNF alpha and IL-6 involvement in surgical trauma. II. In vitro cytokine production. Rev Med Chir Soc Med Nat Iasi 2001; 105: 493–498
   PubMedGoogle Scholar
• Hassett S, Moynagh P, Reen D. TNF-alpha is a mediator of the anti-inflammatory response in a human neonatal model of the non-septic shock syndrome. Pediatr Surg Int 2006; 22: 24–30
   PubMed Web of Science ®Google Scholar
• Ertel W, Kremer J P, Kenney J, et al. Downregulation of proinflammatory cytokine release in whole blood from septic patients. Blood 1995; 85: 1341–1347
   PubMed Web of Science ®Google Scholar
• Bulger E M, Cuschieri J, Warner K, et al. Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock. Ann Surg 2007; 245: 635–641
   PubMed Web of Science ®Google Scholar
• Waydhas C, Nast-Kolb D, Jochum M, et al. Inflammatory mediators, infection, sepsis, and multiple organ failure after severe trauma. Arch Surg 1992; 127: 460–46
   PubMedGoogle Scholar
• Moore F A, Sauaia A, Moore E E, et al. Postinjury multiple organ failure: a bimodal phenomenon. J Trauma 1996; 40: 501–510
   PubMed Web of Science ®Google Scholar
• Casey L C, Balk R A, Bone R C. Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med 1993; 119: 771–778
   PubMed Web of Science ®Google Scholar
• Michie H R, Manogue K R, Spriggs D R, et al. Detection of circulating tumor necrosis factor after endotoxin administration. N Engl J Med 1988; 318: 1481–1486
   PubMed Web of Science ®Google Scholar
• Kieft H, Hoepelman A IM, Zhou W. The sepsis syndrome in a Dutch university hospital. Arch Intern Med 1993; 153: 2241–2247
   PubMedGoogle Scholar
• Marks J D, Marks C B, Luce J M. Plasma tumor necrosis factor in patients with septic shock. Am Rev Respir Dis 1990; 141: 94–97
   PubMed Web of Science ®Google Scholar
• Wang J E, Dahle M K, Yndestad A, et al. Peptidoglycan of Staphylococcus aureus causes inflammation and organ injury in the rat. Crit Care Med 2004; 32: 546–552
   PubMedGoogle Scholar
• Timmerman C P, Mattsson E, Martinez-Martinez L, et al. Induction of release of tumor necrosis factor from human monocytes by staphylococci and staphylococcal peptidoglycans. Infect Immun 1993; 61: 4167–4172
   PubMed Web of Science ®Google Scholar
• Wang J E, Jorgensen P F, Almlof M, et al. Peptidoglycan and lipoteichoic acid from Staphylococcus aureus induce tumor necrosis factor alpha, interleukin 6 (IL-6), and IL-10 production in both T cells and monocytes in a human whole blood model. Infect Immun 2000; 68: 3965–3970
   PubMed Web of Science ®Google Scholar
• Nau R, Eiffert H. Modulation of release of proinflammatory bacterial compounds by antibacterials: potential impact on course of inflammation and outcome in sepsis and meningitis. Clin Microbiol Rev 2002; 15: 95–110
   PubMed Web of Science ®Google Scholar
• Cavaillon J M, Adib-Conquy M, Cloez-Tayarani I, et al. Immunodepression in sepsis and SIRS assessed by ex vivo cytokine production is not a generalized phenomenon: a review. J Endotoxin Res 2001; 7: 85–93
   PubMedGoogle Scholar
• Wilhelm W, Grundmann U, Rensing H, et al. Monocyte deactivation in severe human sepsis or following cardiopulmonary bypass. Shock 2002; 17: 354–360
   PubMedGoogle Scholar
• Wang J E, Warris A, Ellingsen E A, et al. Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infect Immun 2001; 69: 2402–2406
   PubMed Web of Science ®Google Scholar
• Foster S J. Analysis of the autolysins of Bacillus subtilis 168 during vegetative growth and differentiation by using renaturing polyacrylamide gel electrophoresis. J Bacteriol 1992; 174: 464–470
   PubMedGoogle Scholar
• Majetschak M, Flach R, Kreutzfelder E. et al. The extent of traumatic damage determines a graded depression of the endotoxin responsiveness of peripheral blood mononuclear cells from patients with blunt injuries. Crit Care Med 1999; 27: 313–318
   PubMed Web of Science ®Google Scholar
• Casey L C, Balk R A, Bone R C. Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med 1993; 119: 771–778
   PubMed Web of Science ®Google Scholar
• Huynh T, Baker C C, Bracey L W, et al. Adaptive Kupffer cell alterations after fracture trauma in rats. Am J Physiol 1997; 272: G1457–G1462
   PubMedGoogle Scholar
• Muehlstedt S G, Richardson C J, Lyte M, et al. Systemic and pulmonary effector cell function after injury. Crit Care Med 2002; 30: 1322–1326
   PubMedGoogle Scholar
• Sekido N, Mukaida N, Harada A, et al. Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8. Nature 1993; 365: 654–657
   PubMed Web of Science ®Google Scholar
• Giannoudis P V, Smith R M, Perry S L, et al. Immediate IL-10 expression following major orthopaedic trauma: relationship to anti-inflammatory response and subsequent development of sepsis. Intensive Care Med 2000; 26: 1076–1081
   PubMedGoogle Scholar
• Lyons A, Kelly J L, Rodrick M L, et al. Major injury induces increased production of interleukin-10 by cells of the immune system with negative impact on resistance to infection. Ann Surg 1997; 226: 450–458
   PubMedGoogle Scholar
• Klava A, Windsor A, Farmery S M. IL10: a role in the development of post-operative immunosuppression. Arch Surg 1997; 132: 425–429
   PubMedGoogle Scholar
• Randow F, Syrbe U, Meisel C, et al. Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta. J Exp Med 1995; 181: 1887–1892
   PubMed Web of Science ®Google Scholar