Effect of E-Cigarette aerosol exposure on airway inflammation in a murine model of asthma

References

• Ahmad S, Zafar I, Mariappan N, Husain M, Wei CC, Vetal N, Eltoum IA, Ahmad A. 2019. Acute pulmonary effects of aerosolized nicotine. Am J Physiol Lung Cell Mol Physiol. 316:L94–L104.
   PubMed Web of Science ®Google Scholar
• Al-Sawalha N, Alzoubi K, Khabour O, Karaoghlanian N, Ismail Z, Shihadeh A, Eissenberg T. 2020. Effect of electronic cigarette aerosol exposure during gestation and lactation on learning and memory of adult male offspring rats. Physiol Behav. 221:112911.
   PubMed Web of Science ®Google Scholar
• Al-Sawalha NA, Al-Bo'ul HF, Alzoubi KH, Khabour OF, Thanawala VJ. 2017. Effect of prenatal waterpipe tobacco smoke on airway inflammation in murine model of asthma of adult offspring mice. Inhal Toxicol. 29:366–373.
   PubMed Web of Science ®Google Scholar
• Al-Sawalha NA, Migdadi AM, Alzoubi KH, Khabour OF, Qinna NA. 2017. Effect of waterpipe tobacco smoking on airway inflammation in murine model of asthma. Inhal Toxicol. 29:46–52.
   PubMed Web of Science ®Google Scholar
• Antunes MA, Abreu SC, Damaceno-Rodrigues NR, Parra ER, Capelozzi VL, Pinart M, Romero PV, Silva PM, Martins MA, Rocco PR. 2009. Different strains of mice present distinct lung tissue mechanics and extracellular matrix composition in a model of chronic allergic asthma. Respir Physiol Neurobiol. 165:202–207.
   PubMed Web of Science ®Google Scholar
• Balhara J, Gounni AS. 2012. The alveolar macrophages in asthma: a double-edged sword. Mucosal Immunol. 5:605–609.
   PubMed Web of Science ®Google Scholar
• Brown CJ, Cheng JM. 2014. Electronic cigarettes: product characterisation and design considerations. Tob Control. 23(Suppl 2):ii4–ii10.
   PubMed Web of Science ®Google Scholar
• Busse WW, Lemanske RF Jr. 2001. Asthma. N Engl J Med. 344:350–362.
   PubMed Web of Science ®Google Scholar
• Cai Y, Zijlema WL, Doiron D, Blangiardo M, Burton PR, Fortier I, Gaye A, Gulliver J, de Hoogh K, Hveem K, et al. 2017. Ambient air pollution, traffic noise and adult asthma prevalence: a BioSHaRE approach. Eur Respir J. 49:1502127.
   PubMed Web of Science ®Google Scholar
• Callaerts-Vegh Z, Evans KL, Dudekula N, Cuba D, Knoll BJ, Callaerts PF, Giles H, Shardonofsky FR, Bond RA. 2004. Effects of acute and chronic administration of beta-adrenoceptor ligands on airway function in a murine model of asthma. Proc Natl Acad Sci USA. 101:4948–4953.
   PubMed Web of Science ®Google Scholar
• Cataldo DD, Gueders M, Munaut C, Rocks N, Bartsch P, Foidart JM, Noël A, Louis R. 2004. Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases mRNA transcripts in the bronchial secretions of asthmatics. Lab Invest. 84:418–424.
   PubMed Web of Science ®Google Scholar
• Chaudhuri R, McSharry C, McCoard A, Livingston E, Hothersall E, Spears M, Lafferty J, Thomson NC. 2008. Role of symptoms and lung function in determining asthma control in smokers with asthma. Allergy. 63:132–135.
   PubMed Web of Science ®Google Scholar
• Choi JH, Hwang YP, Lee HS, Jeong HG. 2009. Inhibitory effect of Platycodi Radix on ovalbumin-induced airway inflammation in a murine model of asthma. Food Chem Toxicol. 47:1272–1279.
   PubMed Web of Science ®Google Scholar
• Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE. 2017. Pulmonary toxicity of e-cigarettes. Am J Physiol Lung Cell Mol Physiol. 313:L193–L206.
   PubMed Web of Science ®Google Scholar
• Chung KF, Barnes PJ. 1999. Cytokines in asthma. Thorax. 54:825–857.
   PubMed Web of Science ®Google Scholar
• Collaborators, GBDT. 2017. Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: a systematic analysis from the Global Burden of Disease Study 2015. Lancet. 389:1885–1906.
   PubMed Web of Science ®Google Scholar
• Coumou H, Westerhof GA, de Nijs SB, Amelink M, Bel EH. 2019. New-onset asthma in adults: what does the trigger history tell us? J Allergy Clin Immunol Pract. 7:898–905.e1.
   PubMed Web of Science ®Google Scholar
• Dharmage SC, Perret JL, Custovic A. 2019. Epidemiology of asthma in children and adults. Front Pediatr. 7:246.
   PubMed Web of Science ®Google Scholar
• Durrant DM, Metzger DW. 2010. Emerging roles of T helper subsets in the pathogenesis of asthma. Immunol Invest. 39:526–549.
   PubMed Web of Science ®Google Scholar
• Garcia-Arcos I, Geraghty P, Baumlin N, Campos M, Dabo AJ, Jundi B, Cummins N, Eden E, Grosche A, Salathe M, et al. 2016. Chronic electronic cigarette exposure in mice induces features of COPD in a nicotine-dependent manner. Thorax. 71:1119–1129.
   PubMed Web of Science ®Google Scholar
• Ghonim MA, Pyakurel K, Ju J, Rodriguez PC, Lammi MR, Davis C, Abughazleh MQ, Mansy MS, Naura AS, Boulares AH. 2015. DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4+ T-cell function without causing severe combined immunodeficiency. J Allergy Clin Immunol. 135:425–440.
   PubMed Web of Science ®Google Scholar
• Glynos C, Bibli SI, Katsaounou P, Pavlidou A, Magkou C, Karavana V, Topouzis S, Kalomenidis I, Zakynthinos S, Papapetropoulos A. 2018. Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice. Am J Physiol Lung Cell Mol Physiol. 315:L662–L672.
   PubMed Web of Science ®Google Scholar
• Gotts JE, Jordt SE, McConnell R, Tarran R. 2019. What are the respiratory effects of e-cigarettes? BMJ. 366: l5275.
   PubMed Web of Science ®Google Scholar
• Grana R, Benowitz N, Glantz SA. 2014. E-cigarettes: a scientific review. Circulation. 129:1972–1986.
   PubMed Web of Science ®Google Scholar
• Gueders MM, Foidart JM, Noel A, Cataldo DD. 2006. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in the respiratory tract: potential implications in asthma and other lung diseases. Eur J Pharmacol. 533:133–144.
   PubMed Web of Science ®Google Scholar
• Hahn J, Monakhova YB, Hengen J, Kohl-Himmelseher M, Schussler J, Hahn H, Kuballa T, Lachenmeier DW. 2014. Electronic cigarettes: overview of chemical composition and exposure estimation. Tob Induc Dis. 12:23.
   PubMed Web of Science ®Google Scholar
• Halwani R, Al-Muhsen S, Al-Jahdali H, Hamid Q. 2011. Role of transforming growth factor-β in airway remodeling in asthma . Am J Respir Cell Mol Biol. 44:127–133.
   PubMed Web of Science ®Google Scholar
• Hardy E, Hardy-Sosa A, Fernandez-Patron C. 2018. MMP-2: is too low as bad as too high in the cardiovascular system? Am J Physiol Heart Circ Physiol. 315:H1332–h1340.
   PubMed Web of Science ®Google Scholar
• Heijink IH, Pouwels SD, Leijendekker C, de Bruin HG, Zijlstra GJ, van der Vaart H, ten Hacken NH, van Oosterhout AJ, Nawijn MC, van der Toorn M. 2015. Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release. Am J Respir Cell Mol Biol. 52:554–562.
   PubMed Web of Science ®Google Scholar
• Henderson WR Jr, Tang LO, Chu SJ, Tsao SM, Chiang GK, Jones F, Jonas M, Pae C, Wang H, Chi EY. 2002. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med. 165:108–116.
   PubMed Web of Science ®Google Scholar
• Hofstra CL, Van Ark I, Hofman G, Nijkamp FP, Jardieu PM, Van Oosterhout AJ. 1998. Differential effects of endogenous and exogenous interferon-gamma on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma. Am J Respir Cell Mol Biol. 19:826–835.
   PubMed Web of Science ®Google Scholar
• Hoshino A, Tanaka Y, Akiba H, Asakura Y, Mita Y, Sakurai T, Takaoka A, Nakaike S, Ishii N, Sugamura K, et al. 2003. Critical role for OX40 ligand in the development of pathogenic Th2 cells in a murine model of asthma. Eur J Immunol. 33:861–869.
   PubMed Web of Science ®Google Scholar
• Hromis S, Andrijevic I, Matijasevic J, Lalic N, Drvenica M, Crnobrnja J. 2018. The effect of smoking on asthma prevalence and control. Med Pregl. 71:71–75.
   Google Scholar
• Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, Das S, Moshensky A, Bapat S, Pride DT, et al. 2016. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 94:667–679.
   PubMed Web of Science ®Google Scholar
• Ioachimescu OC, Desai NS. 2019. Nonallergic triggers and comorbidities in asthma exacerbations and disease severity. Clin Chest Med. 40:71–85.
   PubMed Web of Science ®Google Scholar
• Kabesch M, Tost J. 2020. Recent findings in the genetics and epigenetics of asthma and allergy. Semin Immunopathol. 42:43–60.
   PubMed Web of Science ®Google Scholar
• Kelly EA, Jarjour NN. 2003. Role of matrix metalloproteinases in asthma. Curr Opin Pulm Med. 9:28–33.
   PubMed Web of Science ®Google Scholar
• Kheradmand F, Rishi K, Werb Z. 2002. Signaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2. J Cell Sci. 115:839–848.
   PubMed Web of Science ®Google Scholar
• Kim DS, Kim SH, Kim BK, Yang MC, Ma JY. 2012. Antiasthmatic effects of herbal complex MA and its fermented product MA128. Evid Based Complement Alternat Med. 2012:769508.
   PubMed Web of Science ®Google Scholar
• Kim SH, Kim BK, Lee YC. 2011. Antiasthmatic effects of hesperidin, a potential Th2 cytokine antagonist, in a mouse model of allergic asthma. Mediators Inflamm. 2011:1–12.
   Web of Science ®Google Scholar
• Ku CM, Lin JY. 2015. Farnesol, a sesquiterpene alcohol in herbal plants, exerts anti-inflammatory and antiallergic effects on ovalbumin-sensitized and -challenged asthmatic mice. Evid Based Complement Alternat Med. 2015:1–12.
   Web of Science ®Google Scholar
• La Rocca G, Anzalone R, Magno F, Farina F, Cappello F, Zummo G. 2007. Cigarette smoke exposure inhibits extracellular MMP-2 (gelatinase A) activity in human lung fibroblasts. Respir Res. 8:23
   PubMed Web of Science ®Google Scholar
• Lambrecht BN, Hammad H, Fahy JV. 2019. The cytokines of asthma. Immunity. 50:975–991.
   PubMed Web of Science ®Google Scholar
• Larche M, Robinson DS, Kay AB. 2003. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol. 111:450–463; quiz 464.
   PubMed Web of Science ®Google Scholar
• Larcombe AN, Janka MA, Mullins BJ, Berry LJ, Bredin A, Franklin PJ. 2017. The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice. Am J Physiol Lung Cell Mol Physiol. 313:L67–L79.
   PubMed Web of Science ®Google Scholar
• Lee CM, Chang JH, Moon DO, Choi YH, Choi IW, Park YM, Kim GY. 2008. Lycopene suppresses ovalbumin-induced airway inflammation in a murine model of asthma. Biochem Biophys Res Commun. 374:248–252.
   PubMed Web of Science ®Google Scholar
• Lee KM, Hoeng J, Harbo S, Kogel U, Gardner W, Oldham M, Benson E, Talikka M, Kondylis A, Martin F, et al. 2018. Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols. Inhal Toxicol. 30:553–567., Jr.
   PubMed Web of Science ®Google Scholar
• Leigh NJ, Lawton RI, Hershberger PA, Goniewicz ML. 2016. Flavourings significantly affect inhalation toxicity of aerosol generated from electronic nicotine delivery systems (ENDS). Tob Control. 25:ii81–ii87.
   PubMed Web of Science ®Google Scholar
• Lerner CA, Sundar IK, Yao H, Gerloff J, Ossip DJ, McIntosh S, Robinson R, Rahman I. 2015. Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung. PLoS One. 10:e0116732.
   PubMed Web of Science ®Google Scholar
• Levy DT, Yuan Z, Li Y, Mays D, Sanchez-Romero LM. 2019. An examination of the variation in estimates of e-cigarette prevalence among U.S. adults. Int J Environ Res Public Health. 16:3164.
   Web of Science ®Google Scholar
• Li L, Hua L, He Y, Bao Y. 2017. Differential effects of formaldehyde exposure on airway inflammation and bronchial hyperresponsiveness in BALB/c and C57BL/6 mice. PLoS One. 12:e0179231.
   PubMed Web of Science ®Google Scholar
• Lim HB, Kim SH. 2014. Inhallation of e-Cigarette Cartridge Solution Aggravates Allergen-induced Airway Inflammation and Hyper-responsiveness in Mice. Toxicol Res. 30:13–18.
   PubMedGoogle Scholar
• Liu J, Xiong H, Cheng Y, Cui C, Zhang X, Xu L, Zhang X. 2013. Effects of taraxasterol on ovalbumin-induced allergic asthma in mice. J Ethnopharmacol. 148:787–793.
   PubMed Web of Science ®Google Scholar
• Ma L, Zeng J, Mo B, Wang C, Huang J, Sun Y, Yu Y, Liu S. 2015. High mobility group box 1: a novel mediator of Th2-type response-induced airway inflammation of acute allergic asthma. J Thorac Dis. 7:1732–1741.
   PubMed Web of Science ®Google Scholar
• Martorana PA, Beume R, Lucattelli M, Wollin L, Lungarella G. 2005. Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke. Am J Respir Crit Care Med. 172:848–853.
   PubMed Web of Science ®Google Scholar
• Mayyas F, Aldawod H, Alzoubi KH, Khabour O, Shihadeh A, Eissenberg T. 2020. Comparison of the cardiac effects of electronic cigarette aerosol exposure with waterpipe and combustible cigarette smoke exposure in rats. Life Sci. 251:117644.
   PubMed Web of Science ®Google Scholar
• McQuibban GA, Gong JH, Tam EM, McCulloch CA, Clark-Lewis I, Overall CM. 2000. Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. Science. 289:1202–1206.
   PubMed Web of Science ®Google Scholar
• Morean ME, Kong G, Cavallo DA, Camenga DR, Krishnan-Sarin S. 2016. Nicotine concentration of e-cigarettes used by adolescents. Drug Alcohol Depend. 167:224–227.
   PubMed Web of Science ®Google Scholar
• Moreira AP, Hogaboam CM. 2011. Macrophages in allergic asthma: fine-tuning their pro- and anti-inflammatory actions for disease resolution. J Interferon Cytokine Res. 31:485–491.
   PubMed Web of Science ®Google Scholar
• Nakao A. 2001. Is TGF-beta1 the key to suppression of human asthma? Trends Immunol. 22:115–118.
   PubMed Web of Science ®Google Scholar
• Nguyen LP, Omoluabi O, Parra S, Frieske JM, Clement C, Ammar-Aouchiche Z, Ho SB, Ehre C, Kesimer M, Knoll BJ, et al. 2008. Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model. Am J Respir Cell Mol Biol. 38:256–262.
   PubMed Web of Science ®Google Scholar
• O'Byrne PM, Inman MD, Adelroth E. 2004. Reassessing the Th2 cytokine basis of asthma. Trends Pharmacol Sci. 25:244–248.
   PubMed Web of Science ®Google Scholar
• Osei AD, Mirbolouk M, Orimoloye OA, Dzaye O, Uddin SMI, Dardari ZA, DeFilippis AP, Bhatnagar A, Blaha MJ. 2019. The association between e-cigarette use and asthma among never combustible cigarette smokers: behavioral risk factor surveillance system (BRFSS) 2016 & 2017. BMC Pulm Med. 19:180.
   PubMed Web of Science ®Google Scholar
• Sampson AP. 2000. The role of eosinophils and neutrophils in inflammation. Clin Exp Allergy. 30(Suppl 1):22–27.
   PubMed Web of Science ®Google Scholar
• Schweitzer KS, Chen SX, Law S, Van Demark M, Poirier C, Justice MJ, Hubbard WC, Kim ES, Lai X, Wang M, et al. 2015. Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures. Am J Physiol Lung Cell Mol Physiol. 309:L175–L187.
   PubMed Web of Science ®Google Scholar
• Shim EJ, Chun E, Lee HS, Bang BR, Kim TW, Cho SH, Min KU, Park HW. 2012. The role of high-mobility group box-1 (HMGB1) in the pathogenesis of asthma. Clin Exp Allergy. 42:958–965.
   PubMed Web of Science ®Google Scholar
• Shimoda T, Obase Y, Kishikawa R, Iwanaga T. 2016. Influence of cigarette smoking on airway inflammation and inhaled corticosteroid treatment in patients with asthma. Allergy Asthma Proc. 37:50–58.
   PubMed Web of Science ®Google Scholar
• Shin IS, Lee MY, Lim HS, Ha H, Seo CS, Kim JC, Shin HK. 2012. An extract of Crataegus pinnatifida fruit attenuates airway inflammation by modulation of matrix metalloproteinase-9 in ovalbumin induced asthma. PLoS One. 7:e45734.
   PubMed Web of Science ®Google Scholar
• Silverman RA, Boudreaux ED, Woodruff PG, Clark S, Camargo CA Jr. 2003. Cigarette smoking among asthmatic adults presenting to 64 emergency departments. CHEST. 123:1472–1479.
   PubMed Web of Science ®Google Scholar
• Song L, Guan XJ, Chen X, Cui ZL, Han FF, Guo XJ, Xu WG. 2014. Mesenchymal stem cells reduce cigarette smoke-induced inflammation and airflow obstruction in rats via TGF-β1 signaling. COPD. 11:582–590.
   PubMedGoogle Scholar
• Sussan TE, Gajghate S, Thimmulappa RK, Ma J, Kim JH, Sudini K, Consolini N, Cormier SA, Lomnicki S, Hasan F, et al. 2015. Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model. PLoS One. 10:e0116861.
   PubMed Web of Science ®Google Scholar
• Thanawala VJ, Forkuo GS, Al-Sawalha N, Azzegagh Z, Nguyen LP, Eriksen JL, Tuvim MJ, Lowder TW, Dickey BF, Knoll BJ, et al. 2013. β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model . Am J Respir Cell Mol Biol. 48:220–229.
   PubMed Web of Science ®Google Scholar
• Thomson NC. 2017. Asthma and smoking-induced airway disease without spirometric COPD. Eur Respir J. 49:1602061.
   PubMed Web of Science ®Google Scholar
• Tveden-Nyborg P, Bergmann TK, Lykkesfeldt J. 2018. Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies. Basic Clin Pharmacol Toxicol. 123:233–235.
   PubMed Web of Science ®Google Scholar
• Uhm TG, Kim BS, Chung IY. 2012. Eosinophil development, regulation of eosinophil-specific genes, and role of eosinophils in the pathogenesis of asthma. Allergy Asthma Immunol Res. 4:68–79.
   PubMed Web of Science ®Google Scholar
• Virag L, Bai P, Bak I, Pacher P, Mabley JG, Liaudet L, Bakondi E, Gergely P, Kollai M, Szabo C. 2004. Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma. Med Sci Monit. 10:BR77-83.
   PubMed Web of Science ®Google Scholar
• Walsh GM. 2001. Eosinophil granule proteins and their role in disease. Curr Opin Hematol. 8:28–33.
   PubMed Web of Science ®Google Scholar
• Wang Q, Khan NA, Muthumalage T, Lawyer GR, McDonough SR, Chuang TD, Gong M, Sundar IK, Rehan VK, Rahman I. 2019. Dysregulated repair and inflammatory responses by e-cigarette-derived inhaled nicotine and humectant propylene glycol in a sex-dependent manner in mouse lung. FASEB Bioadv. 1:609–623.
   PubMedGoogle Scholar
• Wang Z, Zhang H, Sun X, Ren L. 2016. The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-β/Smad signaling and activation of the Nrf2/HO-1 pathway. Mol Med Rep. 14:2389–2396.
   PubMed Web of Science ®Google Scholar
• Wei Y, Liu B, Sun J, Lv Y, Luo Q, Liu F, Dong J. 2015. Regulation of Th17/Treg function contributes to the attenuation of chronic airway inflammation by icariin in ovalbumin-induced murine asthma model. Immunobiology. 220:789–797.
   PubMed Web of Science ®Google Scholar
• Werley MS, Kirkpatrick DJ, Oldham MJ, Jerome AM, Langston TB, Lilly PD, Smith DC, McKinney WJ. Jr. 2016. Toxicological assessment of a prototype e-cigaret device and three flavor formulations: a 90-day inhalation study in rats. Inhal Toxicol. 28:22–38.
   PubMed Web of Science ®Google Scholar
• Whitehead GS, Walker JKL, Berman KG, Foster WM, Schwartz DA. 2003. Allergen-induced airway disease is mouse strain dependent. Am J Physiol Lung Cell Mol Physiol. 285:L32–42.
   PubMed Web of Science ®Google Scholar
• Williams M, Villarreal A, Bozhilov K, Lin S, Talbot P. 2013. Metal and silicate particles including nanoparticles are present in electronic cigarette cartomizer fluid and aerosol. PLoS One. 8:e57987.
   PubMed Web of Science ®Google Scholar
• World Health Organization. 2019. Prevalence of tobacco smoking. https://www.who.int/gho/tobacco/use/en/
   Google Scholar
• Yim YK, Lee H, Hong KE, Kim YI, Ko SK, Kim JE, Lee SY, Park KS. 2010. Anti-inflammatory and Immune-regulatory effects of subcutaneous Perillae Fructus extract injections on OVA-induced asthma in mice. Evid Based Complement Alternat Med. 7:79–86.
   PubMed Web of Science ®Google Scholar
• Zeki AA, Franzi L, Last J, Kenyon NJ. 2009. Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond. Am J Respir Crit Care Med. 180:731–740.
   PubMed Web of Science ®Google Scholar