Circulating heavy chain IgG, a pathological mediator for coronary artery disease, recognizes platelet surface receptors of both prostacyclin and insulin

Reference

• Colman R W, Walsh P N. In: Colman R W, Hirsh J, Marder V J, Saltzman E W, eds. Haemostasis and Thrombosis. Philadelphia, PA: J.B. Lippincott, 1987: 594–605.
   Google Scholar
• Furman M I, Beniot S E, Barnard M R, Valeri C R, Borbone M L, Becker R C, Hechtman H B, Michelson A D. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol 1998; 31: 352–8.
   PubMed Web of Science ®Google Scholar
• Hambegr M, Svenson J, Samuelsson B. Thromboxanes: a new group of bioactive compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci USA 1975; 74: 2994–8.
   Google Scholar
• Moncada S, Gryglewski R J, Bunting S, Vane J R. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable angina substance that inhibits platelet aggrega- tion. Nature 1971; 263: 663–5.
   Google Scholar
• Trovati M, Anfossi G, Massucco P, Maltielo L, Costamagna C, Piretto V, Mularoni E, Cavalot F, Bosin A, Ghigo D. Insulin stimulates nitric oxide synthesis in human platelets and, through nitric oxide increases platelet concentrations of both guanosine 350 cyclic monophosphate adenosine 3,50 cyclic monophosphate. Diabetes 1997; 46: 742–9.
   PubMed Web of Science ®Google Scholar
• Sinha A K, Bhattacharya S, Acharya K, Mazumder S. Stimulation of nitric oxide synthesis and protective role of insulin in acute thrombosis in vivo. Life Sci 1999; 65: 2687–96.
   PubMed Web of Science ®Google Scholar
• Ignarro L J. Biosynthesis and metabolism of endothelium derived nitric oxide. Annu Rev Pharmacol Toxicol 1990; 30: 535–60.
   PubMed Web of Science ®Google Scholar
• Sinha A K, Bhattacharya S, Acharya K, Mazumder S, Bauman W A, Kahn N N. Prevention of thrombosis in vivo nitric oxide. Ind J Physiol Allied Sci 1998; 52: 148–61.
   Google Scholar
• Kahn N N, Sinha A K. Inhibition of prostaglandin E1 induced activation of adenylate cyclase in human blood platelet membrane. Biochim Biophys Acta 1988; 972: 45–53.
   PubMedGoogle Scholar
• Kahn N N, Bauman W A, Sinha A K. Loss of high-affinity prostacyclin receptors in platelets and the lack of prostaglandin-induced inhibition of platelet-stimulated throm- bin generation in subjects with spinal cord injury. Proc Natl Acad Sci USA 1996; 93: 245–9.
   PubMed Web of Science ®Google Scholar
• Kahn N N. Platelet-stimulated thrombin generation and platelet derived growth factors are normalized by insulin and Ca2þ channel blockers. Am J Physiol 1999; 276: E856–62.
   PubMed Web of Science ®Google Scholar
• Kahn N N, Bhattacharya S, Acharya K, Mazumder S, Bauman W A, Sinha A K. Nitric oxide: the ‘second messenger’ of insulin. IUBMB Life 2000; 49: 441–50.
   PubMed Web of Science ®Google Scholar
• Bauman W A, Kahn N N, Grimm D R, Spungen A M. Risk factors for atherogenesis and cardiovascular autonomic func- tion in persons with spinal cord injury. Spinal Cord 1999; 37: 601–16.
   PubMed Web of Science ®Google Scholar
• Samsa G P, Patric C H, Feussner J R. Long term survival of veterans with traumatic spinal cord injury. Arch Neurol 1993; 50: 909–14.
   PubMedGoogle Scholar
• Kahn N N, Bauman W A, Sinha A K. Demonstration of a novel circulating anti-prostacyclin receptor antibody. Proc Natl Acad Sci USA 1997; 94: 8779–82.
   PubMed Web of Science ®Google Scholar
• Yalow R S, Berson S A. Immunoassay of endogenous insulin in man. J Clin Invest 1960; 39: 1157–75.
   PubMed Web of Science ®Google Scholar
• Kahn N N, Sinha A K. Stimulation of prostaglandin E1 binding to human platelet membrane by insulin and the activation of adenylate cyclase. J Biol Chem 1990; 265: 4976–81.
   PubMed Web of Science ®Google Scholar
• Kahn N N, Bauman W A, Sinha A K. Transient decrease of binding of insulin to platelets in acute ischemic heart disease. Am J Med Sci 1994; 307: 21–6.
   PubMed Web of Science ®Google Scholar
• Scatchard G. The attraction of proteins for small molecules and ions. Ann NY Acad Sci 1949; 51: 660–70.
   Web of Science ®Google Scholar
• Laemmli U K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 1970; 227: 680–5.
   PubMed Web of Science ®Google Scholar
• Towbin M, Staehlin Y, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedures and some applications. Proc Natl Acad Sci USA 1989; 76: 43–5.
   Google Scholar
• Roth R A. Insulin. In: Cuatrecasas P, Jacobs S, eds. Handbook ofExperimental Pharmacology, Vol. 92. Berlin: Springer, 1990: 169–81.
   Google Scholar
• Huang X, Miller W. A time efficient linear space local similarity algorithm. Adv Appl Math 1991; 12: 337–57.
   Web of Science ®Google Scholar
• Search Launcher. BCM.TMC.edu
   Google Scholar