Potentiation of antiaggregating effect of prostaglandins by α-tocopherol and quercetin

References

• Kobayashi T, Narumiya S. Function of prostanoid receptors: studies on knockout mice. Prostaglandins Other Lipid Mediat 2002; 68–69:557–73.
   Google Scholar
• Steiner M, Anastasi J. Vitamin E. An inhibitor of the platelet release reaction. J Clin Invest 1976; 57: 732–7.
   PubMed Web of Science ®Google Scholar
• Freedman J E, Farhat J H, Loscalzo J, Keaney J F. a-Tocopherol inhibits aggregation of human platelets by protein kinase C-dependent mechanism. Circulation 1996; 94: 2434–40.
   PubMedGoogle Scholar
• Pace-Asciak C R, Hahn S, Diamandis E P, Soleas G, Goldberg D M. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995; 235: 207–19.
   Google Scholar
• Pignatelli P, Pulcinelli F M, Celestini A, Lenti L, Ghiselli A, Gazzaniga P P, et al. The flavonoids quercetin and catechin synergistically inhibit platelet function by antagonizing the intracellular production of hydrogen peroxide. Am J Clin Nutr 2000; 72: 1150–5.
   Google Scholar
• Ricciarelli R, Zingg J M, Azzi A. Vitamin E 80th anniversary: a double life, not only fighting radicals. IUBMB Life 2001; 52: 71–6.
   PubMedGoogle Scholar
• Mabile L, Bruckdorfer K R, Rice-Evans C. Moderate supplementation with natural alpha-tocopherol decreases platelet aggregation and low-density lipoprotein oxidation. Atherosclerosis 1999; 147: 177–85.
   PubMedGoogle Scholar
• Dogne J M, Leval X D, Benoit P, Delarge J, Masereel B, David J L. Recent advances in antiplatelet agents. Curr Med Chem 2002; 9: 577–89.
   PubMedGoogle Scholar
• Mruk J S, Webster M W, Heras M, Reid J M, Grill D E, Chesebro J H. Flavone-8-acetic acid (Flavonoid) profoundly reduces platelet-dependent thrombosis and vasoconstriction after deep arterial injury in vivo. Circulation 2000; 101: 324–8.
   PubMedGoogle Scholar
• Pignatelli P, Pulcinelli F M, Lenti L, Gazzaniga P P, Violi F. Vitamin E inhibits collagen-induced platelet activation by blunting hydrogen peroxide. Arterioscler Thromb Vasc Biol 1999; 19: 2542–7.
   PubMed Web of Science ®Google Scholar
• Janssen K, Mensink R P, Cox F J, Harryvan J L, Hovenier R, Hollman P C, et al. Effect of the flavonoids quercetin and apigenin on haemostasis in healthy volunteers: results from an in vitro and dietary supplement study. Am J Clin Nutr 1998; 67: 255–62.
   PubMed Web of Science ®Google Scholar
• Azzi A, Gysin R, Kempn P, Ricciarelli R, Villacorta L, Visarius T, et al. The role of a-tocopherol in preventing disease: from epidemiology to molecular events. Mol Aspects Med 2003; 24: 325–36.
   PubMed Web of Science ®Google Scholar
• McAnlis G T, McEneny J, Pearce J, Young I S. Absorption and antioxidant effects of quercetin from onions in man. Eur J Clin Nutr 1999; 53: 92–6.
   PubMedGoogle Scholar
• Goldberg D M, Soleas G J, Yan J. Absorption of three wine- related polyphenols in three different matrices by healthy subjects. Clin Biochem 2003; 36: 79–87.
   PubMedGoogle Scholar
• Wise H, Jones R L. Focus on prostacyclin and its novel mimetics. Trends Pharmacol Sci 1996; 17: 17–21.
   PubMed Web of Science ®Google Scholar
• Schwarz U R, Walter U, Eigenthaler M. Taming platelets with cyclic nucleotides. Biochem Pharmacol 2001; 62: 1153–61.
   PubMed Web of Science ®Google Scholar
• Middleton E Jr, Kandaswami C, Theoharides T C. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000; 52: 673–751.
   PubMed Web of Science ®Google Scholar
• Tzeng S H, Ko W C, Ko F N, Teng C M. Inhibition of platelet aggregation by some flavonoids. Thromb Res 1991; 64: 91–100.
   PubMedGoogle Scholar
• Chi Y S, Jong H G, Son K H, Chang H W, Kang S K, Kim H P. Effects of naturally occurring prenylated flavonoids on enzymes metabolizing arachidonic acid: Cyclooxygenases and lipoxygenases. Biochem Pharmacol 2001; 62: 1185–91.
   PubMedGoogle Scholar
• Lanza F, Beretz A, Stierle A, Corre G, Cazenave J P. Cyclic nucleotide phosphodiesterase inhibitors prevent aggregation of human platelets by raising cyclic AMP and reducing cytoplasmic free calcium mobilization. Thromb Res 1987;45:477–484.
   PubMedGoogle Scholar
• Agullo G, Gamet-Payrastre L, Manenti S, Viala C, Remesy C, Chap H, et al. Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition. BiochemPharmacol 1997; 53: 1649–1657.
   PubMed Web of Science ®Google Scholar
• Gamet-Payrastre L, Manenti S, Gratacap M P, Tulliez J, Chap H, Payrastre B. Flavonoids and the inhibition of PKC and PI 3-kinase. Gen Pharmacol 1999; 32: 279–86.
   PubMedGoogle Scholar
• Lauener R W, Stevens C M, Sayed M R, Salari H, Duronio V. A role for phosphatidylinositol 3-kinase in platelet aggregation in response to low, but not high, concentrations of PAF or thrombin. Biochim Biophys Acta 1999; 1452: 197–208.
   PubMedGoogle Scholar
• Meydani S N, Meydani M, Blumberg J B, Leka L S, Pedrosa M, Diamond R, et al. Assessment of the safety of supplemen- tation with different amounts of vitamin E in healthy older adults. Am J Clin Nutr 1998; 68: 311–8.
   PubMedGoogle Scholar
• Formica J V, Regelson W. Review of the biology of quercetin and related bioflavonoids. Food Chem Toxicol 1995; 33: 1061–80.
   PubMedGoogle Scholar