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Review Articles

Exploring the potential of nanocarriers in antipsoriatic therapeutics

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Pages 2919-2930 | Received 23 Mar 2022, Accepted 09 Jun 2022, Published online: 21 Jun 2022

References

  • Sala M, Elaissari A, Fessi H. Advances in psoriasis physiopathology and treatments: up to date of mechanistic insights and perspectives of novel therapies based on innovative skin drug delivery systems (ISDDS)). J Control Release. 2016;239:182–202.
  • Lo Y, Tsai TF. Updates on the treatment of erythrodermic psoriasis. Psoriasis. 2021;11:59–73.
  • Xie J, Huang S, Huang H, et al. Advances in the application of natural products and the novel drug delivery systems for psoriasis. Front Pharmacol. 2021;12:644952.
  • Mabuchi T, Chang TW, Quinter S, et al. Chemokine receptors in the pathogenesis and therapy of psoriasis. J Dermatol Sci. 2012;65(1):4–11.
  • Pradhan M, Singh D, Singh MR. Novel colloidal carriers for psoriasis: current issues, mechanistic insight and novel delivery approaches. J Control Release. 2013;170(3):380–395.
  • Traub M, Marshall K. Psoriasis–pathophysiology, conventional, and alternative approaches to treatment. Altern Med Rev. 2007;12(4):319–330.
  • Gordon-Elliott JS, Muskin PR. Managing the patient with psychiatric issues in dermatologic practice. Clin Dermatol. 2013;31(1):3–10.
  • Fraga NA, Oliveira MD, Follador I, et al. Psoriasis and uveitis: a literature review. An Bras Dermatol. 2012;87(6):877–883.
  • Singh A, Easwari TS. Recent advances in psoriasis therapy: trends and future prospects. Curr Drug Targets. 2021;22(15):1760–1771.
  • Yan BX, Chen XY, Ye LR, et al. Cutaneous and systemic psoriasis: classifications and classification for the distinction. Front Med. 2021;8:649408.
  • Rajguru JP, Maya D, Kumar D, et al. Update on psoriasis: a review. J Family Med Prim Care. 2020;9(1):20–24.
  • Raharja A, Mahil SK, Barker JN. Psoriasis: a brief overview. Clin Med. 2021;21(3):170–173.
  • Umezawa Y. Psoriatic arthritis. J Dermatol. 2021;48(6):741–749.
  • Bachelez H. Pustular psoriasis: the dawn of a new era. Acta Derm Venereol. 2020;100(3):adv00034.
  • Saleh D, Tanner LS. Guttate psoriasis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021.
  • Crowley JJ, Weinberg JM, Wu JJ, et al. Treatment of nail psoriasis: best practice recommendations from the Medical Board of the National Psoriasis Foundation. JAMA Dermatol. 2015;151(1):87–94.
  • Armstrong AW, Read C. Pathophysiology, clinical presentation, and treatment of psoriasis: a review. JAMA. 2020;323(19):1945–1960.
  • Garg T, Rath G, Goyal AK. Ancient and advanced approaches for the treatment of an inflammatory autoimmune disease − psoriasis. Crit Rev Ther Drug Carrier Syst. 2014;31(4):331–364.
  • Rendon A, Schäkel K. Psoriasis pathogenesis and treatment. IJMS. 2019;20(6):1475.
  • Greb JE, Goldminz AM, Elder JT, et al. Psoriasis. Nat Rev Dis Primers. 2016;2:16082.
  • Louden BA, Pearce DJ, Lang W, et al. A simplified psoriasis area severity index (SPASI) for rating psoriasis severity in clinic patients. Dermatol Online J. 2004;10(2):7.
  • Buechler CR, Veenstra J, Stein Gold L. New topical therapies for psoriasis. Dermatol Rev. 2021;2(5):262–267.
  • Gungor S, Rezigue M. Nanocarriers mediated topical drug delivery for psoriasis treatment. Curr Drug Metab. 2017;18(5):454–468.
  • Rahman M, Alam K, Ahmad MZ, et al. Classical to current approach for treatment of psoriasis: a review. Endocr Metab Immune Disord Drug Targets. 2012;12(3):287–302.
  • Ashcroft DM, Li Wan Po A, Griffiths CE. Therapeutic strategies for psoriasis. J Clin Pharm Ther. 2000;25(1):1–10.
  • Yadav K, Soni A, Singh D, et al. Polymers in topical delivery of anti-psoriatic medications and other topical agents in overcoming the barriers of conventional treatment strategies. Prog Biomater. 2021;10(1):1–17.
  • Kuchekar AB, Pujari RR, Kuchekar SB, et al. Psoriasis: a comprehensive review. Int J Life Sci. 2011;2(6).
  • Nordin UU, Ahmad N, Salim N, et al. Lipid-based nanoparticles for psoriasis treatment: a review on conventional treatments, recent works, and future prospects. RSC Adv. 2021;11(46):29080–29101.
  • Ali F, Neha K, Sharma K, et al. Nanotechnology-based medicinal products and patents: a promising way to treat psoriasis. Curr Drug Deliv. 2022;19.
  • Yu YQ, Yang X, Wu XF, et al. Enhancing permeation of drug molecules across the skin via delivery in nanocarriers: novel strategies for effective transdermal applications. Front Bioeng Biotechnol. 2021;9:200.
  • Reid C, Griffiths CEM. Psoriasis and treatment: past, present and future aspects. Acta Derm Venereol. 2020;100(3):adv00032.
  • Pandey K, Nimisha . An overview on promising nanotechnological approaches for the treatment of psoriasis. Recent Pat Nanotechnol. 2020;14(2):102–118.
  • Kushwaha P, Saxena S, Shukla B. A recent overview on dermatological applications of liposomes. Recent Pat Nanotechnol. 2021;15(4):310–321.
  • Pradhan M, Alexander A, Singh MR, et al. Understanding the prospective of nano-formulations towards the treatment of psoriasis. Biomed Pharmacother. 2018;107:447–463.
  • Jyothi SL, Krishna KL, Shirin VKA, et al. Drug delivery systems for the treatment of psoriasis: current status and prospects. J Drug Deliv Sci Technol. 2021;62:102364.
  • Garg T, Rath G, Goyal AK. Nanotechnological approaches for the effective management of psoriasis. Artif Cells Nanomed Biotechnol. 2016;44(6):1374–1382.
  • Chlapanidas T, Perteghella S, Leoni F, et al. TNF-α blocker effect of naringenin-loaded sericin microparticles that are potentially useful in the treatment of psoriasis. Int J Mol Sci. 2014;15(8):13624–13636.
  • Priyanka NS, Neeraja P, Mangilal T, et al. Formulation and evaluation of gel loaded with microspheres of apremilast for transdermal delivery system. Asian J Pharm Clin Res. 2019;12:411–417.
  • Zielińska A, Carreiró F, Oliveira AM, et al. Polymeric nanoparticles: production, characterization, toxicology and ecotoxicology. Molecules. 2020;25(16):3731.
  • Soliman G, Shaaban O, Hamdan AM. Preparation and evaluation of anthralin biodegradable nanoparticles as a potential delivery system for the treatment of psoriasis. Int J Pharm Pharm Sci. 2015;7(12):36–40.
  • Mao KL, Fan ZL, Yuan JD, et al. Skin-penetrating polymeric nanoparticles incorporated in silk fibroin hydrogel for topical delivery of curcumin to improve its therapeutic effect on psoriasis mouse model. Colloids Surf B Biointerfaces. 2017;160:704–714.
  • Anwer MK, Mohammad M, Ezzeldin E, et al. Preparation of sustained release apremilast-loaded PLGA nanoparticles: in vitro characterization and in vivo pharmacokinetic study in rats. Int J Nanomedicine. 2019;14:1587–1595.
  • Kumar S, Prasad M, Rao R. Topical delivery of clobetasol propionate loaded nanosponge hydrogel for effective treatment of psoriasis: Formulation, physicochemical characterization, antipsoriatic potential and biochemical estimation. Mater Sci Eng C Mater Biol Appl. 2021;119:111605.
  • Makhmalzade BS, Chavoshy F. Polymeric micelles as cutaneous drug delivery system in normal skin and dermatological disorders. J Adv Pharm Technol Res. 2018;9(1):2–8.
  • Jin Y, Zhang X, Zhang B, et al. Nanostructures of an amphiphilic zinc phthalocyanine polymer conjugate for photodynamic therapy of psoriasis. Colloids Surf B Biointerfaces. 2015;128:405–409.
  • Chavoshy F, Zadeh BS, Tamaddon AM, et al. Delivery and anti-psoriatic effect of silibinin-loaded polymeric micelles: an experimental study in the psoriatic skin model. Curr Drug Deliv. 2020;17(9):787–798.
  • Khurana B, Arora D, Narang RK. QbD based exploration of resveratrol loaded polymeric micelles based carbomer gel for topical treatment of plaque psoriasis: in vitro, ex vivo and in vivo studies. J Drug Deliv Sci Technol. 2020;59(59):101901.
  • Dinshaw IJ, Ahmad N, Salim N, et al. Nanoemulsions: a review on the conceptualization of treatment for psoriasis using a green surfactant with low-energy emulsification method. Pharmaceutics. 2021;13(7):1024.
  • Algahtani MS, Ahmad MZ, Ahmad J. Nanoemulsion loaded polymeric hydrogel for topical delivery of curcumin in psoriasis. J Drug Deliv Sci Technol. 2020;59:101847.
  • Kaur A, Katiyar SS, Kushwah V, et al. Nanoemulsion loaded gel for topical co-delivery of clobitasol propionate and calcipotriol in psoriasis. Nanomedicine. 2017;13(4):1473–1482.
  • Sahu S, Katiyar SS, Kushwah V, et al. Active natural oil-based nanoemulsion containing tacrolimus for synergistic antipsoriatic efficacy. Nanomedicine. 2018;13(16):1985–1998.
  • Batheja P, Sheihet L, Kohn J, et al. Topical drug delivery by a polymeric nanosphere gel: Formulation optimization and in vitro and in vivo skin distribution studies. J Control Release. 2011;149(2):159–167.
  • Kilfoyle BE, Sheihet L, Zhang Z, et al. Development of paclitaxel-TyroSpheres for topical skin treatment. J Control Release. 2012;163(1):18–24.
  • Knudsen NØ, Rønholt S, Salte RD, et al. Calcipotriol delivery into the skin with PEGylated liposomes. Eur J Pharm Biopharm. 2012;81(3):532–539.
  • Srisuk P, Thongnopnua P, Raktanonchai U, et al. Physico-chemical characteristics of methotrexate-entrapped oleic acid-containing deformable liposomes for in vitro transepidermal delivery targeting psoriasis treatment. Int J Pharm. 2012;427(2):426–434.
  • Gupta R, Gupta M, Mangal S, et al. Capsaicin-loaded vesicular systems designed for enhancing localized delivery for psoriasis therapy. Artif Cells Nanomed Biotechnol. 2016;44(3):825–834.
  • Doppalapudi S, Jain A, Chopra DK, et al. Psoralen loaded liposomal nanocarriers for improved skin penetration and efficacy of topical PUVA in psoriasis. Eur J Pharm Sci. 2017;96:515–529.
  • Walunj M, Doppalapudi S, Bulbake U, Khan W. Preparation, characterization, and in vivo evaluation of cyclosporine cationic liposomes for the treatment of psoriasis. J Liposome Res. 2020;30(1):68–79.
  • Fathalla D, Youssef EM, Soliman GM. Liposomal and ethosomal gels for the topical delivery of anthralin: preparation, comparative evaluation and clinical assessment in psoriatic patients. Pharmaceutics. 2020;12(5):446.
  • Wang W, Shu GF, Lu KJ, et al. Flexible liposomal gel dual-loaded with all-trans retinoic acid and betamethasone for enhanced therapeutic efficiency of psoriasis. J Nanobiotechnol. 2020;18(1):1–4.
  • Shetty K, Sherje AP. Nano intervention in topical delivery of corticosteroid for psoriasis and atopic dermatitis – a systematic review. J Mater Sci Mater Med. 2021;32(8):88.
  • Parnami N, Garg T, Rath G, et al. Development and characterization of nanocarriers for topical treatment of psoriasis by using combination therapy. Artif Cells Nanomed Biotechnol. 2014;42(6):406–412.
  • Abdelbary AA, AbouGhaly MH. Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: application of Box-Behnken design, in-vitro evaluation and in-vivo skin deposition study. Int J Pharm. 2015;485(1–2):235–243.
  • Moghddam SR, Ahad A, Aqil M, et al. Formulation and optimization of niosomes for topical diacerein delivery using 3-factor, 3-level Box-Behnken design for the management of psoriasis. Mater Sci Eng C Mater Biol Appl. 2016;69:789–797.
  • Marey AA. Preparation and characterization of acitretin-loaded niosomes for psoriasis treatment [electronic theses and dissertations]. The University of Mississippi; 2017. p. 727.
  • Meng S, Sun L, Wang L, et al. Loading of water-insoluble celastrol into niosome hydrogels for improved topical permeation and anti-psoriasis activity. Colloids Surf B Biointerfaces. 2019;182:110352.
  • Patel B, Parikh R. Preparation and formulation of transferosomes containing an antifungal agent for transdermal delivery: application of Plackett-Burman design to identify significant factors influencing vesicle size. J Pharm Bioallied Sci. 2012;4(5):60.
  • Parkash V, Maan S, Chaudhary V, et al. Implementation of design of experiments in development and optimization of transfersomal carrier system of tacrolimus for the dermal management of psoriasis in albino wistar rat. J Bioequiv. 2018;10:98–105.
  • Nimisha DA, Fatima Z, Neema CD. Antipsoriatic and anti-inflammatory studies of Berberis aristata extract loaded nanovesicular gels. Pharmacogn Mag. 2017;13(Suppl 3):S587.
  • Bahramizadeh M, Bahramizadeh M, Kiafar B, et al. Development, characterization and evaluation of topical methotrexate-entrapped deformable liposome on imiquimod-induced psoriasis in a mouse model. Int J Pharm. 2019;569:118623.
  • Gupta P, Jha AK, Prasad M, et al. Soft malleable vesicles: versatile carriers for efficient topical delivery of fungal therapeutics. Drug Res. 2021;71(2):54–61.
  • Zhang YT, Shen LN, Wu ZH, et al. Comparison of ethosomes and liposomes for skin delivery of psoralen for psoriasis therapy. Int J Pharm. 2014;471(1–2):449–452.
  • Chandra A, Aggarwal G, Manchanda S, et al. Development of topical gel of methotrexate incorporated ethosomes and salicylic acid for the treatment of psoriasis. Pharm Nanotechnol. 2019;7(5):362–374.
  • Negi P, Sharma I, Hemrajani C, et al. Thymoquinone-loaded lipid vesicles: a promising nanomedicine for psoriasis. BMC Complement Altern Med. 2019;19(1):334.
  • Zhang Y, Xia Q, Li Y, et al. CD44 assists the topical anti-psoriatic efficacy of curcumin-loaded hyaluronan-modified ethosomes: a new strategy for clustering drug in inflammatory skin. Theranostics. 2019;9(1):48–64.
  • Guo T, Lu J, Fan Y, et al. TPGS assists the percutaneous administration of curcumin and glycyrrhetinic acid coloaded functionalized ethosomes for the synergistic treatment of psoriasis. Int J Pharm. 2021;604:120762.
  • Jain A, Doppalapudi S, Domb AJ, et al. Tacrolimus and curcumin co-loaded liposphere gel: synergistic combination towards management of psoriasis. J Control Release. 2016;243:132–145.
  • Jain A, Pooladanda V, Bulbake U, et al. Liposphere mediated topical delivery of thymoquinone in the treatment of psoriasis. Nanomedicine. 2017;13(7):2251–2262.
  • Agrawal U, Gupta M, Vyas SP. Capsaicin delivery into the skin with lipidic nanoparticles for the treatment of psoriasis. Artif Cells Nanomed Biotechnol. 2015;43(1):33–39.
  • Pradhan M, Singh D, Singh MR. Fabrication, optimization and characterization of triamcinolone acetonide loaded nanostructured lipid carriers for topical treatment of psoriasis: Application of Box Behnken design, in vitro and ex vivo studies. J Drug Deliv Sci Technol. 2017;41:325–333.
  • Ferreira M, Barreiros L, Segundo MA, et al. Topical co-delivery of methotrexate and etanercept using lipid nanoparticles: a targeted approach for psoriasis management. Colloids Surf B Biointerfaces. 2017;159:23–29.
  • Kaur N, Sharma K, Bedi N. Topical nanostructured lipid carrier based hydrogel of mometasone furoate for the treatment of psoriasis. Pharm Nanotechnol. 2018;6(2):133–143.
  • Viegas JSR, Praça FG, Caron AL, et al. Nanostructured lipid carrier co-delivering tacrolimus and TNF-α siRNA as an innovate approach to psoriasis. Drug Deliv Transl Res. 2020;10(3):646–660.
  • Pradhan M, Alexander A, Singh MR, et al. Statistically optimized calcipotriol fused nanostructured lipid carriers for effectual topical treatment of psoriasis. J Drug Deliv Sci Technol. 2021;61:102168.
  • Madan JR, Khobaragade S, Dua K, et al. Formulation, optimization, and in vitro evaluation of nanostructured lipid carriers for topical delivery of Apremilast. Dermatol Ther. 2020;33(3):e13370.
  • Biswasroy P, Pradhan D, Kar B, et al. Recent advancement in topical nanocarriers for the treatment of psoriasis. AAPS PharmSciTech. 2021;22(5):164.
  • Bessar H, Venditti I, Benassi L, et al. Functionalized gold nanoparticles for topical delivery of methotrexate for the possible treatment of psoriasis. Colloids Surf B Biointerfaces. 2016;141:141–147.
  • Fratoddi I, Benassi L, Botti E, et al. Effects of topical methotrexate loaded gold nanoparticle in cutaneous inflammatory mouse model. Nanomedicine. 2019;17:276–286.
  • Cerra S, Matassa R, Beltrán AM, et al. Insights about the interaction of methotrexate loaded hydrophilic gold nanoparticles: spectroscopic, morphological and structural characterizations. Mater Sci Eng C Mater Biol Appl. 2020;117:111337.
  • Mikhailova EO. Silver nanoparticles: mechanism of action and probable bio-application. JFB. 2020;11(4):84.
  • David L, Moldovan B, Vulcu A, et al. Green synthesis, characterization and anti-inflammatory activity of silver nanoparticles using European black elderberry fruits extract. Colloids Surf B Biointerfaces. 2014;122:767–777.
  • Gangadevi V, Thatikonda S, Pooladanda V, et al. Selenium nanoparticles produce a beneficial effect in psoriasis by reducing epidermal hyperproliferation and inflammation. J Nanobiotechnology. 2021;19(1):101.
  • Sabri AH, Ogilvie J, Abdulhamid K, et al. Expanding the applications of microneedles in dermatology. Eur J Pharm Biopharm. 2019;140:121–140.
  • Shravanth H, Osmani RAM, Jyothi SL, et al. Microneedles-based drug delivery for the treatment of psoriasis. J Drug Deliv Sci Technol. 2021;64:102668.
  • Paleco R, Vučen SR, Crean AM, et al. Enhancement of the in vitro penetration of quercetin through pig skin by combined microneedles and lipid microparticles. Int J Pharm. 2014;472(1–2):206–213.
  • Chen Y, Chen BZ, Wang QL, et al. Fabrication of coated polymer microneedles for transdermal drug delivery. J Control Release. 2017;265:14–21.
  • Du H, Liu P, Zhu J, et al. Hyaluronic acid-based dissolving microneedle patch loaded with methotrexate for improved treatment of psoriasis. ACS Appl Mater Interfaces. 2019;11(46):43588–43598.
  • Liang L, Fei WM, Zhao ZQ, et al. Improved imiquimod-induced psoriasis like dermatitis using microneedles in mice. Eur J Pharm Biopharm. 2021;164:20–27.
  • Yu K, Yu X, Cao S, et al. Layered dissolving microneedles as a need-based delivery system to simultaneously alleviate skin and joint lesions in psoriatic arthritis. Acta Pharm Sin B. 2021;11(2):505–519.

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