Advanced search
Publication Cover
International Journal of Radiation Biology Volume 76, 2000 - Issue 2
Submit an article Journal homepage
25
Views
25
CrossRef citations to date
0
Altmetric
Research Article

High-LET-induced chromosome aberrations in V79 cells analysed in first and second post-irradiation metaphases

S. Ritter, E. Nasonova, E. Gudowska-Nowak, M. Scholz, G. Kraft Radiologische Klinik, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
Pages 149-161 | Published online: 03 Jul 2009

  • BAUCHINGER, M. and SCHMID, E., 1998, LET dependence of yield ratios of radiation-induced intra- and interchromosomal aberrations in human lymphocytes. International Journal of Radiation Biology, 74, 17-25.
  • BAUCHINGER, M., SCHMID, E. and BRASELMANN, H., 1986, Cell survival and radiation-induced chromosome aberrations. 2. Experimental findings in human lymphocytes analyzed in first and second post-irradiation metaphases. Radiation and Environmental Biophysics, 25, 253-260.
  • BENDER, M. A., GRIGGS, H. G. and BEDFORD, J. S., 1974, Mechanisms of chromosomal aberration production, III. Chemicals and ionizing radiation. Mutation Research, 23, 197-212.
  • BOEI, J. J. W. A., VERMEULEN, S. and NATARAJAN, A. T., 1996, Detection of chromosomal aberrations by fluorescence in situ hybridization in the first three post-irradiation divisions of human lymphocytes. Mutation Research, 349, 127-135.
  • BOEI, J. J. W. A., VERMEULEN, S. and NATARAJAN, A. T., 1997, Differential involvement of chromosomes 1 and 4 in the formation of chromosomal aberrations in human lymphocytes after X-irradiation. International Journal of Radiation Biology, 72, 139-145.
  • BRASELMANN, H., BAUCHINGER, M. and SCHMID, E., 1986, Cell survival and radiation-induced chromosome aberrations. I. Derivation of formulae for the determination of transmission and survival parameters of aberrations. Radiation and Environmental Biophysics, 25, 243-251.
  • BRENNER, D. J. and SACHS, R. K., 1994, Commentary: Chromosomal 'fingerprint' of prior exposure to densely ionizing radiation. Radiation Research, 140, 134-142.
  • CARLSON, J. G., 1989, Chinese hamster ovary cell mitosis and its response to ionizing radiation: a morphological analysis of the living cell. Radiation Research, 118, 311-323.
  • CARRANO, A. V. and HEDDLE, J. A., 1973, The fate of chromosome aberrations. Journal of Theoretical Biology, 38, 289-304.
  • CHADWICK, K. H. and LEENHOUTS, H. P., 1978, The rejoining of DNA double-strand breaks and a model for the formation of chromosomal rearrangements. International Journal of Radiation Biology, 33, 517-529.
  • COLLYN-D'HOOGHE, M., HEMON, D., GlLET, R., CURTIS, S. B.,VALLERON, A. J. and MALAISE, E. P., 1981, Comparative effects of Co y-rays and neon and helium ions on cell cycle duration and division probability of EMT 6 cells. A time-lapse cinematography study. International Journal of Radiation Biology, 39, 297-306.
  • COLLYN-D'HOOGHE, M., HEMON, D., VALLERON, A. J. andMALAISE, E. P., 1980, Comparative effects of ionizing radiations on cycle time and mitotic duration. A timelapse cinematography study. Radiation Research, 81, 384-392.
  • CORNFORTH, M. N. and BEDFORD, J. S., 1987, A quantitative comparison of potentially lethal damage repair and the rejoining of interphase chromosome breaks in low passage normal human fibroblasts. Radiation Research, 111, 385-405.
  • DEWEY, W. C., FURMAN, S. C. and MILLER, H. H., 1970, Comparison of lethality and chromosomal damage induced by X-rays in synchronized Chinese hamster cells in vitro. Radiation Research, 43, 561-581.
  • DURANTE, M., GROSSI, G. F., NAPOLITANO, M., PUGLIESE, M. and GIALANELLA, G., 1992, Chromosome damage induced by high-LET a-particles in plateau-phase C3H 10T1/2 cells. International Journal of Radiation Biology, 62, 571-580.
  • EDWARDS, A. A., FINNON, P., MOQUET, J. E., LLOYD, D. C., DARROUDI, F. and NATARAJAN, A. T., 1994, The effectiveness of high-energy neon ions in producing chromosomal aberrations in human lymphocytes. Radiation Protection Dosunetry, 52, 299-303.
  • EDWARDS, A. A., LLOYD, D. C., PROSSER, J. S., FINNON, P. and MOQUET, J. E., 1986, Chromosome aberrations induced in human lymphocytes by 8.7 MeV protons and 23.5 MeV helium-3 ions. International Journal of Radiation Biology, 50, 137-145.
  • GRIFFIN, C. S., MARDSEN, S. J., STEVENS, D. L., SIMPSON, P. and SAVAGE, J. R. K., 1995, Frequencies of complex chromosome exchange aberrations induced by 238Pu aparticles and detected by fluorescence in situ hybridization using single chromosome-specific probes. International Journal of Radiation Biology, 67, 431-439.
  • ISCN, 1978, An international system for human cytogenetic nomenclature. Cytogenetics and Cell Genetics, 21, 309-404.
  • KAUFMAN,G. E., MILLER, M. W., SAVAGE, J. R. and PAPWORTH, D. G., 1974, Chromosome aberration yields from multiple fixation regimes. Journal of Theoretical Biology, 44, 91-103.
  • KRAFT, G., DAUES, H. W., FISCHER, B, KOPF, U., LEIBOLD, H. P., QUIS, D., STELZER, H., KIEFER, J., SCHÖPFER, R., SCHNEIDER, E., WEBER, U., WULF, H. and DERTINGER, H., 1980, Irradiation chamber and sample changes for biological samples. Nuclear Instruments and Methods, 168, 175-179.
  • LLOYD, D. C., DOLPHIN, G. W., PURROT, R. J. and TIPPER, P. A., 1977, The effect of X-ray induced mitotic delay on chromosome aberration yields in human lymphocytes. Mutation Research, 42, 401-412.
  • LOBACHEVSKY, P. N. and FOMINYKH, E. V., 1991, Calculation of the radiation-induced delay in cell division during a study of the induction of chromosome aberrations. Radiobiologya, 35, 59-64.
  • LUCKE-HUHLE, C., BLAKELY, E. A., CHANG, P. Y. and TOBIAS, A. T., 1979, Drastic Ga arrest in mammalian cells after irradiation with heavy-ion beams. Radiation Research, 79, 97-112.
  • NAKAMURA, N., TUCKER, J. D., BAUCHINGER, M., LITTLEFIELD, L. G., LLOYD, D. C., PRESTON, R. J., SASAKI, M. S., AWA, A. A. and WOLFF, S., 1998, F values as cytogenetic fingerprints of prior exposure to different radiation qualities: prediction, reality and future. Radiation Research, 150, 492-494.
  • NASONOVA, E., RITTER, S., FOMENKOVA, T. and KRAFT, G., 1998, Induction of chromosomal damage in CHO-K1 and their repair-deficient mutant xrs5 by X-ray and particle irradiation. Advances in Space Research, 22, 569-578.
  • PERRY, P. and WOLF, S., 1974, New Giemsa method for differential staining of sister chromatids. Mature, 251, 156-158.
  • PYATKIN, E. K., NUGIS, V. U. and POKROVSKAYA, V. N., 1984, Proliferative activity and frequency of chromosome aberrations during the first mitosis in 50-, 60- and 70-h cultures of irradiated lymphocytes and in mixed cultures of irradiated and non-irradiated cells. Radiobiologya, 24, 310-314.
  • RITTER, S., KRAFT-WEYRATHER, W., SCHOLZ, M. and KRAFT, G., 1990, Influence of radiation quality on heavy ion induced chromosome aberrations in V79 cells. Radiation Protection Dosmetry, 31, 257-260.
  • RITTER, S., NASONOVA, E., SCHOLZ, M., KRAFT-WEYRATHER, W. and KRAFT, G., 1996, Comparison of chromosomal damage induced by X-rays and Ar-ions with an LET of 1840keV/µm in Gl V79 cells. International Journal of Radiation Biology, 69, 155-166.
  • ROOTS, R., HOLLEY, W., CHATERJEE, A., IRIZARRY, M. and KRAFT, G., 1990, The formation of strand breaks in DNA after high-LET irradiation: a comparison of data from in vitro and cellular systems. International Journal of Radiation Biology, 58, 55-69.
  • SASAKI, H., YATAGAI, F., KANAI, T., FURUSAWA, Y., HANAOKA, F., ZHU, W. G. and MEHNATI, P., 1997, Dependence of induction of interphase death of Chinese hamster ovary cells exposed to accelerated ions on linear energy transfer. Radiation Research, 148, 449-454.
  • SASAKI, M. S. and NORMAN, A., 1967, Selection against chromosome aberrations in human lymphocytes. Nature, 214, 502-503.
  • SAVAGE, J. R. K., 1975, Classification and relationships of induced chromosomal structural changes. Journal of Meditai Genetics, 12, 103-122.
  • SCHOLZ, M., 1992, Zellzyklusverzögerungen synchroner Zellpopulationen nach Schwerionenbestrahlung. PhD thesis, University of Heidelberg, GSI Report 92-28.
  • SCHOLZ, M., Kraft-Weyrather, W., Ritter, S. and KRAFT, G., 1994, Cell cycle delays induced by heavy ion irradiation of synchronous mammalian cells. International Journal of Radiation Biology, 66, 59-75.
  • SCHOLZ, M., RITTER, S. and KRAFT, G., 1998, Analysis of chromosome damage based on the time course of aberrations. International Journal of Radiation Biology, 74, 325-331.
  • SEVANKAIEV, A. V., ZHERBIN, E. A., LUCHNIK, N. N., O BATUROV, G. M., KOZLOV, V. M., TATTE, E. and KAPCHIGASHEV, S. P., 1979, Genetical effects induced by neutrons in human peripheral blood lymphocytes in vitro. Genetika, 15, 1046-1060.
  • SKARSGARD, L. D., KIHLMAN, B. A., PARKER, L., PUJARA, C. M. and RICHARDSON, S., 1967, Survival, chromosome abnormalities and recovery in heavy ion and X-ray irradiated mammalian cells. Radiation Research, 7(Suppl.), 208-221.
  • SUZUKI, K., SUZUKI, M., NAKANO, K., KANEKO, I. and WATANABE, M., 1990, Analysis of chromatid damage in G2-phase induced by heavy ions and X-rays. International Journal of Radiation Biology, 58, 781-789.
  • TAKATSUJI, T. and SASAKI, M. S., 1984, Dose-effect relationship of chromosome aberrations induced by 23MeV alphaparticles in human lymphocytes. International Journal of Radiation Biology, 45, 237-243.
  • TESTARD, I., DUTRILLAUX, B. and SABATIER, L., 1997, Chromosomal aberrations induced by heavy ions and Xrays. International Journal of Radiation Biology, 58, 781-789.
  • TREMP, J., 1981, Chromosome aberrations and cell survival in irradiated mammalian cells. Radiation Research, 85, 554-566.
  • WU, H., DURANTE, M., GEORGE, K. and YANG, C., 1997, Induction of chromosome aberrations in human cells by charged particles. Radiation Research, 148, S102-S107.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.