Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATMndash; a study based on DNA from formalin fixed paraffin embedded tissue samples

References

• LENT SOMA tables. Radiotherapy & Oncology 1995; 35: 17–60
   PubMed Web of Science ®Google Scholar
• Andreassen C N. Can risk of radiotherapy-induced normal tissue complications be predicted from genetic profiles?. Acta Oncologica 2005; 44: 801–815
   PubMed Web of Science ®Google Scholar
• Andreassen C N, Alsner J, Overgaard J. Does variability in normal tissue reactions after radiotherapy have a genetic basis – where and how to look for it?. Radiotherapy & Oncology 2002; 64: 131–140
   PubMed Web of Science ®Google Scholar
• Andreassen C N, Alsner J, Overgaard J, Herskind C, Haviland J, Owen R, Homewood J, Bliss J, Yarnold J. TGFB1 polymorphisms are associated with risk of late normal tissue complications in the breast after radiotherapy for early breast cancer. Radiotherapy & Oncology 2005a; 75: 18–21
   PubMed Web of Science ®Google Scholar
• Andreassen C N, Alsner J, Overgaard M, Overgaard J. Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes. Radiotherapy & Oncology 2003; 69: 127–135
   PubMed Web of Science ®Google Scholar
• Andreassen C N, Sorensen F B, Overgaard J, Alsner J. Optimisation and validation of methods to assess single nucleotide polymorphisms (SNPs) in archival histological material. Radiotherapy & Oncology 2004; 72: 351–356
   PubMed Web of Science ®Google Scholar
• Andreassen C N, Overgaard J, Alsner J, Overgaard M, Herskind C, Cesaretti J A, Atencio D P, Green S, Formenti S C, Stock R G, Rosenstein B S. ATM sequence variants and risk of radiation induced subcutaneous fibrosis after post-mastectomy radiotherapy. International Journal of Radiation Oncology, Biology, Physics 2006; 64: 776–783
   PubMed Web of Science ®Google Scholar
• Angele S, Romestaing P, Moullan N, Vuillaume M, Chapot B, Friesen M, Jongmans W, Cox D G, Pisani P, Gerard J P, Hall J. ATM haplotypes and cellular response to DNA damage: Association with breast cancer risk and clinical radiosensitivity. Cancer Research 2003; 63: 8717–8725
   PubMed Web of Science ®Google Scholar
• Awad M R, El Gamel A, Hasleton P, Turner D M, Sinnott P J, Hutchinson I V. Genotypic variation in the transforming growth factor-beta1 gene: association with transforming growth factor-beta1 production, fibrotic lung disease, and graft fibrosis after lung transplantation. Transplantation 1998; 66: 1014–1020
   PubMed Web of Science ®Google Scholar
• Baumann M, Holscher T, Begg A C. Towards genetic prediction of radiation responses: ESTRO's GENEPI project. Radiotherapy & Oncology 2003; 69: 121–125
   PubMed Web of Science ®Google Scholar
• Bentzen S M, Christensen J J, Overgaard J, Overgaard M. Some methodological problems in estimating radiobiological parameters from clinical data. Alpha/beta ratios and electron RBE for cutaneous reactions in patients treated with postmastectomy radiotherapy. Acta Oncologica 1988; 27: 105–116
   Google Scholar
• Bentzen S M, Overgaard J. Patient-to-patient variability in the expression of radiation-induced normal tissue injury. Seminars in Radiation Oncology 1994; 4: 68–80
   PubMedGoogle Scholar
• Bentzen S M, Overgaard M, Thames H D, Christensen J J, Overgaard J. Early and late normal-tissue injury after postmastectomy radiotherapy alone or combined with chemotherapy. International Journal of Radiation Biology 1989a; 56: 711–715
   PubMed Web of Science ®Google Scholar
• Bentzen S M, Thames H D, Overgaard M. Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study. Radiotherapy & Oncology 1989b; 15: 267–274
   PubMed Web of Science ®Google Scholar
• Bermudez M G, Piyamongkol W, Tomaz S, Dudman E, Sherlock J K, Wells D. Single-cell sequencing and mini-sequencing for preimplantation genetic diagnosis. Prenatal Diagnosis 2003; 23: 669–677
   PubMed Web of Science ®Google Scholar
• Chang-Claude J, Popanda O, Tan X L, Kropp S, Helmbold I, von Fournier D, Haase W, Sautter-Bihl M L, Wenz F, Schmezer P, Ambrosone C B. Association between polymorphisms in the DNA repair genes, XRCC1, APE1 and XPD and acute side effects of radiotherapy in breast cancer patients. Clinical Cancer Research 2005; 11: 4802–4809
   PubMed Web of Science ®Google Scholar
• De Ruyck K, Van Eijkeren M, Claes K, Vral A, De Neve W, Thierens H. Association of single nucleotide polymorphisms in TGFb1 with late radiation induced damage to normal tissues in patients treated with radiotherapy for gynaecological tumors. Meetings Abstract # W 30, 35th Annual Meeting of the European Environmental Mutagen Society. 2005
   Google Scholar
• De Ruyck K, Van Eijkeren M, Claes K, Morthier R, De Paepe A, Vral A, De Ridder L, Thierens H. Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: Association with single nucleotide polymorphisms in XRCC1, XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes. International Journal of Radiation Oncology, Biology, Physics 2006; 62: 1140–1149
   Google Scholar
• Fernet M, Hall J. Genetic biomarkers of therapeutic radiation sensitivity. DNA Repair (Amsterdam) 2004; 3: 1237–1243
   PubMed Web of Science ®Google Scholar
• Green H, Ross G, Peacock J, Owen R, Yarnold J, Houlston R. Variation in the manganese superoxide dismutase gene (SOD2) is not a major cause of radiotherapy complications in breast cancer patients. Radiotherapy & Oncology 2002; 63: 213–216
   PubMed Web of Science ®Google Scholar
• Hall E J, Schiff P B, Hanks G E, Brenner D J, Russo J, Chen J, Sawant S G, Pandita T K. A preliminary report: Frequency of A-T heterozygotes among prostate cancer patients with severe late responses to radiation therapy. The Cancer Journal from Scientific America 1998; 4: 385–389
   PubMed Web of Science ®Google Scholar
• Johansen J, Bentzen S M, Overgaard J, Overgaard M. Relationship between the in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis, telangiectasia, and skin erythema after radiotherapy. Radiotherapy & Oncology 1996; 40: 101–109
   PubMed Web of Science ®Google Scholar
• Moullan N, Cox D G, Angele S, Romestaing P, Gerard J P, Hall J. Polymorphisms in the DNA repair gene XRCC1, breast cancer risk, and response to radiotherapy. Cancer Epidemiology, Biomarkers & Prevention 2003; 12: 1168–1174
   PubMed Web of Science ®Google Scholar
• Overgaard J. Effect of misonidazole and hyperthermia on the radiosensitivity of a C3H mouse mammary carcinoma and its surrounding normal tissue. British Journal of Cancer 1980; 41: 10–21
   PubMed Web of Science ®Google Scholar
• Overgaard M, Bentzen S M, Christensen J J, Madsen E H. The value of the NSD formula in equation of acute and late radiation complications in normal tissue following 2 and 5 fractions per week in breast cancer patients treated with postmastectomy irradiation. Radiotherapy & Oncology 1987; 9: 1–11
   PubMed Web of Science ®Google Scholar
• Overgaard M, Christensen J J, Johansen H, Nybo-Rasmussen A, Brincker H, van der Kooy P L, Frederiksen P L, Laursen F, Laursen J, Panduro N E, Sørensen N E, Gadeberg C C, Hjelm-Hansen M, Overgaard J, West K, Zedeler K. Postmastectomy irradiation in high-risk breast cancer patients. Present status of the Danish Breast Cancer Cooperative trials. Acta Oncologica 1988; 27: 707–714
   PubMed Web of Science ®Google Scholar
• Quarmby S, Fakhoury H, Levine E, Barber J, Wylie J, Hajeer A H, West C, Stewart A, Magee B, Kumar S. Association of transforming growth factor beta-1 single nucleotide polymorphisms with radiation-induced damage to normal tissues in breast cancer patients. International Journal of Radiation Biology 2003; 79: 137–143
   PubMed Web of Science ®Google Scholar
• Saito H, Tsujitani S, Oka S, Kondo A, Ikeguchi M, Maeta M, Kaibara N. An elevated serum level of transforming growth factor-beta 1 (TGF-beta 1) significantly correlated with lymph node metastasis and poor prognosis in patients with gastric carcinoma. Anticancer Research 2000; 20: 4489–4493
   PubMed Web of Science ®Google Scholar
• Shim K S, Kim K H, Han W S, Park E B. Elevated serum levels of transforming growth factor-beta1 in patients with colorectal carcinoma: Its association with tumor progression and its significant decrease after curative surgical resection. Cancer 1999; 85: 554–561
   PubMed Web of Science ®Google Scholar
• Suit H D, Wette R. Theoretical considerations on the influence of dose fractionation on effectiveness of radiation therapy. National Cancer Institute Monograph 1967; 24: 225–241
   PubMedGoogle Scholar
• Syrris P, Carter N D, Metcalfe J C, Kemp P R, Grainger D J, Kaski J C, Crossman D C, Francis S E, Gunn J, Jeffery S, Heathcote K. Transforming growth factor-beta1 gene polymorphisms and coronary artery disease. Clinical Science (London) 1998; 95: 659–667
   PubMedGoogle Scholar
• Van Hoeyveld E, Houtmeyers F, Massonet C, Moens L, Van Ranst M, Blanckaert N, Bossuyt X. Detection of single nucleotide polymorphisms in the mannose-binding lectin gene using minor groove binder-DNA probes. Journal of Immunological Methods 2004; 287: 227–230
   PubMed Web of Science ®Google Scholar
• Wilhelm J, Pingoud A. Real-time polymerase chain reaction. Chembiochem 2003; 4: 1120–1128
   PubMed Web of Science ®Google Scholar