315
Views
17
CrossRef citations to date
0
Altmetric
Original Articles

Effect of long-term occupational exposure to extremely low-frequency electromagnetic fields on proinflammatory cytokine and hematological parameters

ORCID Icon, ORCID Icon, &
Pages 1573-1580 | Received 01 Mar 2019, Accepted 12 Jun 2019, Published online: 05 Aug 2019

References

  • Aldinucci C, Pessina G. 1998. Biological effects of pulsed electromagnetic fields: Induction of cytokines by peripheral blood mononuclear cells. Pflugers Arch, New York (NY): Springer Verlag; p. R25–R25.
  • Asmah R, Yeboah G, Asare-Anane H, Antwi-Baffour S, Archampong T, Brown C, Amegatcher G, Adjei D, Dzudzor B, Akpalu J. 2015. Relationship between oxidative stress and haematological indices in patients with diabetes in the Ghanaian population. J Clin Endocrinol Diabetes. 1:1–7.
  • Bagheri Hosseinabadi M, Khanjani N, Ebrahimi MH, Haji B, Abdolahfard M. 2019. The effect of chronic exposure to extremely low-frequency electromagnetic fields on sleep quality, stress, depression and anxiety. Electromagn Biol Med. 38:96–101.
  • Cakir DU, Yokus B, Akdag MZ, Sert C, Mete N. 2009. Alterations of hematological variations in rats exposed to extremely low frequency magnetic fields (50 Hz). Arch Med Res. 40:352–356.
  • Cam ST, Firlarer A, Ozden S, Canseven AG, Seyhan N. 2011. Occupational exposure to magnetic fields from transformer stations and electric enclosures in Turkey. Electromagn Biol Med. 30:74–79.
  • Coico R, Sunshine G, Benjamini E. 2003. Immunology. A short course. Hoboken, Hoboken (NJ): John Wiley & Sons.
  • Cossarizza A, Angioni S, Petraglia F, Genazzani AR, Monti D, Capri M, Bersani F, Cadossi R, Franceschi C. 1993. Exposure to low frequency pulsed electromagnetic fields increases interleukin-1 and interleukin-6 production by human peripheral blood mononuclear cells. Exp Cell Res. 204:385–387.
  • De Kleijn S, Bouwens M, Verburg-Van Kemenade BM, Cuppen JJ, Ferwerda G, Hermans PW. 2011. Extremely low frequency electromagnetic field exposure does not modulate toll-like receptor signaling in human peripheral blood mononuclear cells. Cytokine. 54:43–50.
  • Fear NT, Simpson J, Roman E. 2005. Childhood cancer and social contact: the role of paternal occupation (United Kingdom). Cancer Cause Control. 16:1091–1097.
  • Frahm J, Lantow M, Lupke M, Weiss DG, Simko M. 2006. Alteration in cellular functions in mouse macrophages after exposure to 50 Hz magnetic fields. J Cell Biochem. 99:168–177.
  • Ghotbi MR, Mardi H, Khanjani N, Parvaresh N. 2015. Occupational exposure to steady magnetic fields and mental health of workers at the copper electrolysis unit. JSS. 1:1–10.
  • Guerriero F, Ricevuti G. 2016. Extremely low frequency electromagnetic fields stimulation modulates autoimmunity and immune responses: a possible immuno-modulatory therapeutic effect in neurodegenerative diseases. Neural Regen Res. 11:1888–1895.
  • Ikeda K, Shinmura Y, Mizoe H, Yoshizawa H, Yoshida A, Kanao S, Sumitani H, Hasebe S, Motomura T, Yamakawa T, et al. 2003. No effects of extremely low frequency magnetic fields found on cytotoxic activities and cytokine production of human peripheral blood mononuclear cells in vitro. Bioelectromagnetics. 24:21–31.
  • Institute of Electrical and Electronics Engineers 2010. ANSI/IEEE C95.3.1-2010 - IEEE Recommended Practice for Measurements and Computations of Electric, Magnetic, and Electromagnetic Fields with Respect to Human Exposure to Such Fields, 0 Hz to 100 kHz. New York (NY): IEEE.
  • International Agency for Research on Cancer Working Group on the Evaluation of Carcinogenic Risks to Humans 2002. Non-ionizing Radiation: Static and extremely low-frequency (ELF) electric and magnetic fields. Lyon (France): IARC Monogr Eval Carcinog Risks Humans.
  • Jonai H, Villanueva MB, Yasuda A. 1996. Cytokine profile of human peripheral blood mononuclear cells exposed to 50 Hz EMF. Ind Health. 34:359–368.
  • Kheifets L, Renew D, Sias G, Swanson J. 2010. Extremely low frequency electric fields and cancer: assessing the evidence. Bioelectromagnetics. 31:89–101.
  • Kim SJ, Jang YW, Hyung KE, Lee DK, Hyun KH, Jeong SH, Min KH, Kang W, Jeong JH, Park S-Y, et al. 2017. Extremely low-frequency electromagnetic field exposure enhances inflammatory response and inhibits effect of antioxidant in RAW 264.7 cells. Bioelectromagnetics. 38:374–385.
  • Lai H, Singh NP. 2004. Magnetic-field-induced DNA strand breaks in brain cells of the rat. Environ Health Perspect. 112:687–694.
  • Lai J, Zhang Y, Zhang J, Liu X, Ruan G, Chaugai S, Tang J, Wang H, Chen C, Wang DW. 2016. Effects of 100-μT extremely low frequency electromagnetic fields exposure on hematograms and blood chemistry in rats. J Radiat Res. 57:16–24.
  • Lauwerys B, Houssiau F. 2013. Involvement of cytokines in the pathogenesis of systemic lupus erythematosus. Austin (TX): Landes Bioscience. [accessed 2019 Feb 30]. https://www.ncbi.nlm.nih.gov/books/NBK6470/.
  • Li Q, Engelhardt JF. 2006. Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase. J Biol Chem. 281:1495–1505.
  • Liu X, Zhao L, Yu D, Ma S, Liu X. 2013. Effects of extremely low frequency electromagnetic field on the health of workers in automotive industry. Electromagn Biol Med. 32:551–559.
  • Lupke M, Rollwitz J, Simko M. 2004. Cell activating capacity of 50 Hz magnetic fields to release reactive oxygen intermediates in human umbilical cord blood-derived monocytes and in Mono Mac 6 cells. Free Radic Res. 38:985–993.
  • Margonato V, Nicolini P, Conti R, Zecca L, Veicsteinas A, Cerretelli P. 1995. Biologic effects of prolonged exposure to ELF electromagnetic fields in rats: II. 50 Hz magnetic fields. Bioelectromagnetics. 16:343–355.
  • Mattsson M-O, Simko M. 2012. Is there a relation between extremely low frequency magnetic field exposure, inflammation and neurodegenerative diseases? A review of in vivo and in vitro experimental evidence. Toxicology. 301:1–12.
  • Nadimi H, Jalili A, Mohammadi K, Nadimi V. 2017. Studying the amount of blood parameters and liver enzymes in the workers of sanandaj power plant. OJCD. 07:45–57.
  • Olmos G, Lladó J. 2014. Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity. Mediators Inflamm. 2014:861231.
  • Pall ML. 2013. Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects. J Cell Mol Med. 17:958–965.
  • Petrini C, Dupuis ML, Polichetti A, Ramoni C, Vecchia P. 1997. Tumor necrosis factor α and interferon γ production by human peripheral blood mononuclear cells exposed in vitro to sinusoidal 50 Hz magnetic fields. Bioelectrochem Bioenerg. 44:121–125.
  • Ravandi MRG, Mardi H, Khanjani N, Barkhordari A. 2016. Occupational exposure to steady magnetic fields and its effect on workers blood indices at an electrolysis unit. J Magn. 21:255–260.
  • Ren K, Torres R. 2009. Role of interleukin-1beta during pain and inflammation. Brain Res Rev. 60:57–64.
  • Rollwitz J, Lupke M, Simko M. 2004. Fifty-hertz magnetic fields induce free radical formation in mouse bone marrow-derived promonocytes and macrophages. Biochim Biophys Acta. 1674:231–238.
  • Salehi I, Sani KG, Zamani A. 2013. Exposure of rats to extremely low-frequency electromagnetic fields (ELF-EMF) alters cytokines production. Electromagn Biol Med. 32:1–8.
  • Salerno S, Lo Casto A, Caccamo N, D'anna C, De Maria M, Lagalla R, Scola L, Cardinale AE. 1999. Static magnetic fields generated by a 0.5 T MRI unit affects in vitro expression of activation markers and interleukin release in human peripheral blood mononuclear cells (PBMC). Int J Radiat Biol. 75:457–463.
  • Santini MT, Rainaldi G, Indovina PL. 2009. Cellular effects of extremely low frequency (ELF) electromagnetic fields. Int J Radiat Biol. 85:294–313.
  • Scheller J, Chalaris A, Schmidt-Arras D, Rose-John S. 2011. The pro- and anti-inflammatory properties of the cytokine interleukin-6. Biochim Biophys Acta. 1813:878–888.
  • Selmaoui B, Lambrozo J, Sackett-Lundeen L, Haus E, Touitou Y. 2011. Acute exposure to 50-Hz magnetic fields increases interleukin-6 in young healthy men. J Clin Immunol. 31:1105–1111.
  • Sharifian A, Gharavi M, Pasalar P, Aminian O. 2009. Effect of extremely low frequency magnetic field on antioxidant activity in plasma and red blood cells in spot welders. Int Arch Occup Environ Health. 82:259–266.
  • Simkó M, Mattsson MO. 2004. Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro: possible immune cell activation. J Cell Biochem. 93:83–92.
  • Simkó M. 2004. Induction of cell activation processes by low frequency electromagnetic fields. Sci World J. 4:4–22.
  • Simkó M. 2007. Cell type specific redox status is responsible for diverse electromagnetic field effects. Curr Med Chem. 14:1141–1152.
  • Starkov AA, Chinopoulos C, Fiskum G. 2004. Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium. 36:257–264.
  • Tiwari R, Lakshmi N, Bhargava S, Ahuja Y. 2015. Epinephrine, DNA integrity and oxidative stress in workers exposed to extremely low-frequency electromagnetic fields (ELF-EMFs) at 132 kV substations. Electromagn Biol Med. 34:56–62.
  • Wyszkowska J, Jędrzejewski T, Piotrowski J, Wojciechowska A, Stankiewicz M, Kozak W. 2018. Evaluation of the influence of in vivo exposure to extremely low-frequency magnetic fields on the plasma levels of pro-inflammatory cytokines in rats. Int J Radiat Biol. 94:909–917.
  • Zhang Y, Lai J, Ruan G, Chen C, Wang DW. 2016. Meta-analysis of extremely low frequency electromagnetic fields and cancer risk: a pooled analysis of epidemiologic studies. Environ Int. 88:36–43.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.