- ALFER, T., MOTHERSILL, C. and SEYMOUR, C. B., 1988, Lethal mutations attributable to misrepair of Q1esions. International Journal of Radiation Biology, 54, 525-530.
- BORN, R. and TROTT, K. R., 1988, Clonogenicity of the progeny of surviving cells after irradiation., International Journal of Radiation Biology, 53, 319-330.
- BOUKAMP, P., STANBRIDGE, E. J., Foo, D. Y., CERUTTI, P. A., and FUSENIG, N. E., 1990, C-Ha-ras oncogene expression in immortalised human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy., Cancer Research, 50, 2840-2847.
- BRANCH, P., AQUILINA, G., BIGNIMI, M. and KARRAN, P., 1993, Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage., Nature, 362, 652-654.
- CARON, R. M., NAGASAWA, H, Yu, Y, PFENNING, T., VETROVS, H. and LITTLE, J. B., 1997, Evidence for a role for genomic instability in radiation-induced mutagenesis., Radiation Oncology Investigations, 5, 119-123.
- CHANG, W. P. and LITTLE, J. B., 1992, Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation., Carcinogenesis, 13, 923-928.
- CLUTTON, S. M., TOWNSEND, K. M. S, WALKER, C, ANSELL, J. D. and WRIGHT, E. G., 1996, Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures., Carcinogenesis, 17, 1633-1639.
- COLUCCI, S., MOTHERSILL, C., HARNEY, J., GAMBLE, C., SEYMOUR, C. B. and ARRAND, J. E., 1997, Induction of multiple PCR-SSCPE mobility shifts in p53 exons in cultures of normal human urothelium exposed to lowdose gamma radiation., International Journal of Radiation Biology, 72, 21-31.
- DESHPLANDE, A., GOODWIN, E. H., BAILEY, S. M., MARRONE, B. L. and LEHNERT, B. E., Alpha-particle-induced sister chromatid exchange in normal human lung fibroblasts: evidence for an extranuclear target., Radiation Research, 145, 260-267.
- FRANK, J. P. and WILLIAMS, J. R., 1982, X-ray induction of persistent hypersensitivity to mutation., Science, 216, 307308.
- GORGOJO, L. and LITTLE, J. B., 1989, Expression of lethal mutations in the progeny of irradiated mammalian cells., International Journal of Radiation Biology, 55, 619-630.
- HALL, E. J., 1994, Radiobiology for the Radiobiologist, 4th edition (New York and Philadelphia: Lippincott).
- HAUFTMANN, N. and CADENAS, E., 1997, The oxygen paradox: biochemistry of active oxygen. In Oxidative Stress and the Molecular Biology of Antioxidant Defenses, edited by J. G. Scandalios (Cold Spring Harbour Laboratory Press), pp. 1-20.
- KADHIM, M. A., LORIMORE, S. A., TOWNSEND, K. M. S., GOODHEAD, D. T., BUCKLE, V. J. and WRIGHT, E. G., 1995, Radiation-induced genomic instability: delayed cytogenetic aberrations and apoptosis in primary human bone marrow cells., International Journal of Radiation Biology, 57, 287-293.
- KADHIM, M., MACDONALD, D. A., GOODHEAD, S. A., LORIMORE, S. A, MARSDEN, S. J. and WRIGHT, E. G., 1992, Tramsmission of chromosomal instability after plutonium alpha-particle irradiation., Nature, 355, 738-740.
- KADHIM, M. A., WALKER, C. A., PLUMB, M. A. and WRIGHT, E. G., 1996, No association between p53 status and alpha-particle-induced chromosomal instability in human lymphoblastoid cells., International Journal of Radiation Biology, 69, 167-174.
- KROEMER, G., 1997, The proto-oncogene bcl-2 and its role in regulating apoptosis., Nature Medicine, 3, 614-620.
- LIMOLI, C. L., KAPLAN, M. I., PHILIPS, J. W., ADAIR, G. M., and MORGAN, W. F., 1997, Differential induction of chromosomal instability by DNA strand breaking agents., Cancer Research, 57, 4048-4056.
- LOEB, L. A., 1991, Mutator phenotype may be required for multistage carcinogenesis., Cancer Research, 51, 3075-3079.
- MANTI, L., JAMALI, M., PRISE, K. M., MICHAEL, B. and TROTT, K.-R., 1997, Genomic instability in Chinese hamster cells after exposure to X-rays or alpha particles of different mean linear energy transfer., Radiation Research, 147, 22-28.
- MENDONCA, M. S., ANTONIO, R. J. and REDPATH, J. L., 1993, Delayed heritable damage and epigenetics in radiationinduced neoplastic transformation of human hybrid cells., Radiation Research, 134, 209-216.
- MORGAN, W. F, DAY, J. P., KAPLAN, M. I., MCGHEE, E. M. and LIMOLI, C. L., 1996, Genomic instability induced by ionising radiation., Radiation Research, 146, 247-258.
- MOTHERSILL, C, HARNEY, J, LYNG, F, COTTELL, D. and SEYMOUR, C. B., 1995, Primary expiants of normal human uroepithelium show an unusual response to low doses of Cobalt 60 gamma rays., Radiation Research, 142, 181-187.
- MOTHERSILL, C. and SEYMOUR, C. B., 1997a, Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells: possible evidence of a 'Bystander Effect'., International Journal of Radiation Biology, 71, 421-427.
- MOTHERSILL, C. and SEYMOUR, C. B., 1997b, Survival of human epithelial cells irradiated with cobalt 60 as microcolonies or single cells., International Journal of Radiation Biology, 72, 597-606.
- NAGAZAWA, H. and LITTLE, J. B., 1992, Induction of sisterchromatid exchanges by extremely low doses of alpha particles., Cancer Research, 52, 6394-6396.
- O'REILLY, J. and MOTHERSILL, C., 1997, Delayed cell death following exposure of human and fish cells to UVA and UVB., International Journal of Radiation Biology, 72, 111-119.
- O'REILLY, S, MOTHERSILL, C. and SEYMOUR, C. B., 1994, Lethal mutations occur at a constant rate in human keratinocytes following carcinogen treatment., International Journal of Radiation Biology, 76, 134-142.
- PAQUETTE, B. and LITTLE, J. B., 1994, In vivo enhancement of genomic instability in minisatellite sequences of mouse C3H 10T1/2 cells transformed in vitro by X-rays., Cancer Research, 54, 3173-3178.
- PUCK, T. T. and MARCUS, P. I., 1956, Action of X-rays on mammalian cells., Journal of Experimental Medicine, 103, 653-666.
- RICHTER, C. and SCHWEIZER, M., 1997, Oxidative stress in mitochondria. In Oxidative Stress and the Molecular Biology of Antioxidant Definses, edited byJ. G. Scandalios (Cold Spring Harbour Laboratory Press), pp. 169-200.
- SENTMAN,C. L., SHUTTER, J. R., HOCKENBERRY, D., KANAGAWA, O. and KORYSMEYER, S. J., 1991, Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes., Cell, 67, 879-888.
- SEYMOUR, C. B, MOTHERSILL, C. and ALPER, T., 1986, High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation., International Journal of Radiation Biology, 50, 167-169.
- SEYMOUR, C. B. and MOTHERSILL, C., 1992, All colonies of CHO cells surviving gamma radiation contain abnormal cells., Mutation Research, 267, 19-30.
- ZAMZAMI, N., MARCHETTI, P., CASTEDO, M., HIRSCH, T., SUSIN, S., MASSE, B. and KROEMER, G., 1996, Inhibitors of permeability transition interfere with the disruption of mitochondrial transmembrane potential during apoptosis., FEBS Letters, 384, 53-57.
Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.