- Altenburger , R , Boedeker , W. , Faust , M. and Grimme , L.H. 1993 . “ Aquatic toxicology analysis of combination effects ” . In Handbook of Hazardous Materials , Edited by: Com , M. 15 – 17 . San Diego, CA : Academic Press .
- Anon . 1988 . Hazardous chemicals in common use: need for worldwide endeavour to protect environment from toxic waste . New Perspect. , 18 : 24 – 6 .
- Anon . 1990 . Commission for the Future in Our Common Future , 268 Melbourne : Oxford University Press . National Research Council, Toxicity Testing. Washington, OC National Academy Press [1984]. As quoted by
- Ashford , N.A. and Miller , C.S. 1991 . Chemical exposures - low levels and high stakes , New York : Van Nostrand Reinhold .
- Calabrese , E.J. 1991 . Multiple chemical interaction , Chelsea, MI : Lewis .
- Conney , A.H. 1982 . Induction of microsomal enzymes by polycyclic aromatic hydrocarbons. GHA Clowes Memorial Lecture . Cancer Res. , 42 : 4875 – 917 .
- Conney , A.H. and Burns , J.J. 1972 . Metabolic interactions among environmental chemicals and drugs . Science. , 172 : 576 – 86 .
- Conney , A.H. , Welch , R.M. , Kuntzman , R and Burns , J.J. 1966 . Effects of pesticides on drug and steroid metabolism . Pharmacol. Ther. , 8 : 2 – 8 .
- Guengerich , FP. and Liebler , D.C. 1985 . Enzymic activation of chemicals to toxic metabolites . CRC Crit. Rev. Toxicol. , 14 : 259 – 307 .
- Heuser , G. , Wojdani , A. and Heuser , S. 1993 . “ Diagnostic markers of multiple chemical sensitivity ” . In Multiple Chemical Sensitivities , Washington, DC : Board on Environmental Studies and Toxicology Commission on Life Sciences, National Research Council, National Academy Press .
- Jacobs , M.W. , Coates , J.A. , Deffino , J.J. , Bitton , G. , Davis , WM. and Garcia , K.L. 1993 . Comparison of sediment extract microtox toxicity with semi-volatile organic priority pollutant concentrations . Arch. Environ. Contam. Taxicol. , 24 : 461 – 8 .
- Nebert , D.W. and Gunzales , F.J. 1985 . Cytochrome P450 gene expression and regulation . Trends Pharmacal. Sci. , 6 : 160 – 4 .
- Poland , A. , Smith , D. , Kuntzman , R , Jacobson , M. and Conney , A.H . 1970 . Effect of intensive occupational exposure to DDT on on phenylbutazone and coitisol metabolism in human subjects. din . Pharmacol. Ther. , 10 : 724 – 32 .
- Pollak , J.K. 1993 . The Toxicity of Chemical Mixtures , Sydney : Centre for Human Aspects of Science and Technology & The Public Interest Advocacy Centre .
- Pollak , J.K. Free radical biochemistry of contaminants . Preceding? of the Third National Workshop on the Health, Risk Assessment and Management of Contaminated Sites . Edited by: Langley , A. , Markey , B. and Hill , H. Adelaide : South Australian Health Commission . Contaminated Sites Monograph Series No. S
- Raucy , J.L. 1995 . Risk assessment toxicity from chemical exposure resulting from enhanced expression of CYP4502E1 . Toxicol. , 105 : 217 – 23 .
- Rea , W.J. 1994 . Chemical sensitivity, sources of total body load , Vol. 2 , Boca Raton, FL : Lewis .
- Richardson , HL , Stier , E and Borsos-Nachtnebel , E . 1952 . Liver tumor inhibition and adrenal histologie responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered . Cancer Res. , 12 : 356 – 61 .
- Sexton , K. , Beck , B.D. , Bingham , E , Brain , J.D. , DeMarini , D.M. , Hertzberg , R.C , O'Flaherty , E.J. and Pounds , J.G. 1995 . Chemical mixtures from a public health perspective: the importance of research for informed decision making . Tbxicol. , 105 : 429 – 41 .
- Sheehan , D. 1994 . Environmental biochemistry . Biochemist , 16 : 34 – 7 .
- Siddiqui , A , AIi , B. and Srivastava , S.P. 1991 . Heterogeneous effects of ethylenebisdithiocarbamate (EBDC) pesticides on oxidative metabolism of xenobiotics . Pharmacol. Taxicol. , 69 : 13 – 16 .
- Tyrer , J.H. , Eadie , M.J. , Sutherland , J.M. and Hooper , W.D. 1970 . Outbreak of anticonvulsant intoxication in an Australian city . Br. Med. J. , 4 : 271 – 3 .
- US Environmental Protection Agency . 1996 . Proposed guidelines for carcinogenic risk assessment Office of Research and Development , Washington DC : EPA/600/P-92/003C .
- Vesell , E.S. 1987 . “ Methods to assess drug-drug and drug-chemical interactions: problems that arise in their application to the prediction of health hazards from exposure to multiple environmental chemicals ” . In Methods for Assessing the Effects of Mixtures of Chemicals. SCOPE 30 , Edited by: Vouk , VB. 795 – 811 . Chichester : Wiley .
- Witte , L , Jacobi , H and Juhl-Strauss , U. 1995 . Correlation of synergistic cytotoxic effects of environmental chemicals in human fibroblasts with their lipophilicity . Chemosphere. , 31 : 4041 – 9 .
- Wrighton , S.A. and Stevens , J.C. 1992 . The human hepatic cytochromes P450 involved in drug metabolism . Crit. Rev. Tboxicol. , 22 : 1 – 21 .
- Yang , R.S.H. , ed. 1994 . Toxicology of Chemical Mixtures , New York : Academic Press .
- Yang , R.S.H. , Hong , H.L. and Boorman , G.A. 1989 . Toxicology of chemical mixtures: experimental approaches, underlying concepts and some results . Toxicol. Letts. , 49 : 183 – 97 .
A short review of the problems posed by xenobiotics in chemical mixtures and the role of mixed function oxidases
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