162
Views
12
CrossRef citations to date
0
Altmetric
Research Article

PTS1-independent targeting of isocitrate lyase to peroxisomes requires the PTS1 receptor Pex5p

, , &
Pages 61-69 | Published online: 09 Jul 2009

References

  • Becker, D. M. and Guarente, L., 1990, High efficiency transformation of yeast by electroporation. Methods in Enzymology, 194, 182 – 187.
  • Beeckmans, S., Khan, S., Van Driessche, E. and Kanerek, L., 1994, A specific association between the glyoxylic acid cycle enzymes isocitrate lyase and malate synthase. European Journal of Biochemistry, 224, 197 –201.
  • Beevers, H., 1961, Metabolic production of sucrose from fat. Nature, 191, 433 –436.
  • Behari, R. and Baker, A., 1993, The carboxyl terminus of isocitrate lyase is not essential for import into glyoxysomes in an in vitro system. Journal of Biological Chemistry, 268, 7315 -7322.
  • Britton, K. L., Langridge, S. J., Baker, P. J., Weeradechapon, K., Sedelnikova, S. E., de Lucas, J. R., Rice, D. W. and Turner, G., 2000, The crystal structure and active site location of isocitrate lyase from the fungus Aspergillus nidulans. Structure, 8, 349 –362.
  • Crookes, W. J. and Olsen, L. J., 1998, The effects of chaperones and the influence of protein assembly on peroxisomal protein import. Journal of Biological Chemistry, 273, 17236–17242.
  • Distel, B., Erdmann, R., Gould, S. J., Blobel, G., Crane, D. I., Cregg,J. M., Dodt, G., Fujiki, Y., Goodman, J. M., Just, W. W., Kiel, J., Kunau, W. H., Lazarow, P. B., Mannaerts, G. P., Moser, H. W., Osumi, T., Rachubinski, R. A., Roscher, A., Subramani, S.,Tabak, H. F., Tsukamoto, T., Valle, D., vander Klei, I., van Veldhoven, P. P. and Veenhuis, M., 2001, Unified nomenclature for peroxisome biogenesis factors. Journal of Cell Biology, 135, 1 –3.
  • Eastmond, P. J., Germain, V., Lange, P. R., Bryce, J. H., Smith, S.M. and Graham, I. A., 2000, Postgerminative growth and lipid catabolism in oilseeds lacking the glyoxylate cycle. Proceedings of the National Academy of Sciences USA, 97, 5669 -5674.
  • Elgersma, Y., Vanroermund, C. W. T., Wanders, R. J. A. and Tabak,H. F., 1995, Peroxisomal and mitochondrial carnitine acetyltrans- ferases of Saccharomyces cerevisiae are encoded by a single gene. EMBO Journal, 14, 3472 -3479.
  • Elgersma, Y., Vos, A., van den Berg, M., van Roermund, C. W. T., van der Sluijs, P., Distel, B. and Tabak, H. F., 1996, Analysis of the carboxyl-terminal peroxisomal targeting signal 1 in a homo- logous context in Saccharomyces cerevisiae. Journal of Biological Chemistry, 271, 26375–26382.
  • Erdmann, R. and Kunau, W. H., 1994, Purification and immunolo- calization of the peroxisomal 3-oxoacyl-CoA thiolase from Sac- charomyces cerevisiae. Yeast, 10, 1173 -1182.
  • Gao, X. P., Marrison, J. L., Pool, M. R., Leech, R. M. and Baker, A., 1996, Castor bean isocitrate lyase lacking the putative peroxisomal targeting signal 1 ARMis imported into plant peroxisomes both in vitro and in vivo. Plant Physiology, 112, 1457 -1464.
  • Gatto, G. J., Geisbrecht, B. V., Gould, S. J. and Berg, J. M., 2000, Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5. Nature Structural Biology, 7, 1091 -1095.
  • Germain, V., Rylott, E. L., Larson, T. R., Sherson, S. M., Bechtold, N., Carde, J. P., Bryce, J. H., Graham, I. A. and Smith, S. M., 2001, Requirement for 3-ketoacyl-CoA thiolase-2 in peroxisome development, fatty acid beta-oxidation and breakdown of triacyl- glycerol in lipid bodies of Arabidopsis seedlings. Plant Journal, 28, 1 –12.
  • Glover, J. R., Andrews, D. W. and Rachubinski, R. A., 1994, Saccharomyces cerevisiae peroxisomal thiolase is imported as a dimer. Proceedings of the National Academy USA, 91, 10541–10545.
  • Gurvitz, A., Wabnegger, L., Langer, S., Hamilton, B., Ruis, H. and Hartig, A., 2001, The tetratricopeptide repeat domains of human, tobacco, and nematode PEX5 proteins are functionally inter- changeable with the analogous native domain for peroxisomal import of PTS1-terminated proteins in yeast. Molecular Genetics and Genomics, 265, 276 –286.
  • Hayashi, M., Toriyama, K., Kondo, M. and Nishimura, M., 1998, 2,4- Dichlorophenoxybutyric acid-resistant mutants of Arabidopsis have defects in glyoxysomal fatty acid beta-oxidation. Plant Cell, 10, 183 –195.
  • Klein, A. T. J., van den Berg, M., Bottger, G., Tabak, H. F. and Distel, B., 2002, Saccharomyces cerevisiae Acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p. Journal of Biological Chemistry, 277, 25011–25019.
  • Kornberg, H. L. and Krebs, H. A., 1957, Synthesis of cell constituents from C-2 units by a modified tricarboxylic acid cycle. Nature, 179, 988 –991.
  • Kragler, F., Lametschwandtner, G., Christmann, J., Hartig, A. and Harada, J. J., 1998, Identification and analysis of the plant peroxisomal targeting signal 1 receptor NtPEX5. Proceedings of the National Academy of Sciences USA, 95, 13336–13341.
  • Kragler, F., Langeder, A., Raupachova, J., Binder, M. and Hartig, A., 1993, Two independent peroxisomal targeting signals in catalase A of Saccharomyces cerevisiae. Journal of Cell Biology, 120, 665 –673.
  • Kunze, M., Kragler, F., Binder, M., Hartig, A. and Gurvitz, A., 2002, Targeting of malate synthase 1 to the peroxisomes of Sacchar- omyces cerevisiae cells depends on growth on oleic acid medium. European Journal of Biochemistry, 269, 915 –922.
  • Lametschwandtner, G., Brocard, C., Fransen, M., Van Veldhoven, P., Berger, J. and Hartig, A., 1998, The difference in recognition of terminal tripeptides as peroxisomal targeting signal 1 between yeast and human is due to different affinities of their receptor Pex5p to the cognate signal and to residues adjacent to it. Journal of Biological Chemistry, 273, 33635–33643.
  • Lee, M. S., Mullen, R. T. and Trelease, R. N., 1997, Oilseed isocitrate lyases lacking their essential type 1 peroxisomal targeting signal are piggybacked to glyoxysomes. Plant Cell, 9,185 -197.
  • Liepman, A. H. and Olsen, L. J., 2001, Peroxisomal alanine: glyoxylate aminotransferase (AGT1) is a photorespiratory en- zyme with multiple substrates in Arabidopsis thaliana. Plant Journal, 25, 487 –498.
  • Martin, C. and Northcote, D. H., 1982, The action of exogenous GA3 on isocitrate lyase mRNA in germinating castor bean seeds. Planta, 154, 174 –183.
  • Marzioch, M., Erdmann, R., Veenhuis, M. and Kunau, W. H., 1994, PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2- containing protein, into peroxisomes. EMBO Journal, 13, 4908 -4918.
  • McNew, J. A. and Goodman, J. M., 1994, An oligomeric protein is imported into peroxisomes in vivo. Journal of Cell Biology, 127, 1245 -1257.
  • Miller, J. H., 1972, Experiments in Molecular Genetics (Cold Spring Harbor Laboratory, Cold Spring Harbor), pp. 352 –355.
  • Mullen, R. T., Lee, M. S., Flynn, C. R. and Trelease, R. N., 1997, Diverse amino acid residues function within the type 1 perox- isomal targeting signal. Implications for the role of accessory residues upstream of the type 1 peroxisomal targeting signal. Plant Physiology, 115, 881 –889.
  • Olsen, L. J., Ettinger, W. F., Damsz, B., Matsudaira, K., Webb, M. A. and Harada, J. J., 1993, Targeting of glyoxysomal proteins to peroxisomes in leaves and roots of a higher-plant. Plant Cell, 5,941 -952.
  • Purdue, P. E. and Lazarow, P. B., 2001, Peroxisome biogenesis. Annual Review of Cell and Developmental Biology, 17, 701 –752. Sacksteder, K. A. and Gould, S. J., 2000, The genetics of peroxisome biogenesis. Annual Review of Genetics, 34, 623 –652.
  • Sparkes, I. A. and Baker, A., 2002, Peroxisome biogenesis and protein import in plants animals and yeasts: enigma and varia- tions? Molecular Membrane Biology, 19, 171 –185.
  • Subramani, S., Koller, A. and Snyder, W. B., 2000, Import of peroxisomal matrix and membrane proteins. Annual Review of Biochemistry, 69, 399 –418.
  • Taylor, K. M., Kaplan, C. P., Gao, X. P. and Baker, A., 1996, Localization and targeting of isocitrate lyases in Saccharomyces cerevisiae. Biochemical Journal, 319, 255 –262.
  • Van den Bosch, H., Schutgens, R. B. H. and Wanders, R. J. A., 1992, Biochemistry of peroxisomes. Annual Review of Biochem- istry, 61, 157 –197.
  • Wach, A., Brachat, A., Pohlmann, R. and Philippsen, P., 1994, New heterologous modules for classical or PCR-based gene disrup- tions in S. cerevisiae. Yeast, 10, 1793 -1808.
  • Wanders, R. J. A., 1999, Peroxisomal disorders: clinical, biochem- ical, and molecular aspects. Neurochemical Research, 24, 565 – 580.
  • Yang, X. D., Purdue, P. E. and Lazarow, P. B., 2001, Eci1p uses a PTS1 to enter peroxisomes: either its own or that of a partner, Dci1p. European Journal of Cell Biology, 80, 126 –138.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.