Prothymosin alpha-receptor associates with lipid rafts in PHA-stimulated lymphocytes

References

• Brown DA, London E. Structure of detergent-resistant membrane microdomains: does phase separation occur in biological membranes?. Biochem Biophys Res Commun 1997; 240: 1–7
   PubMed Web of Science ®Google Scholar
• Anderson RG. The caveolae membrane system. Annu Rev Biochem 1998; 67: 199–225
   PubMed Web of Science ®Google Scholar
• Simons K, Ikonen E. Functional rafts in cell membranes. Nature 1997; 387: 569–572
   PubMed Web of Science ®Google Scholar
• Eramo A, Sargiacomo M, Ricci-Vitiani L, Todaro M, Stassi G, Messina CGM, Parolini I, Loti F, Sette G, Peschle C, De Maria R. CD95 death-inducing signaling complex formation and internalization occur in lipid rafts of type I and type II cells. Eur J Immunol 2004; 34: 1930–1940
   PubMedGoogle Scholar
• Muppidi JR, Tschopp J, Siegel RM. Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity 2004; 21: 461–465
   PubMed Web of Science ®Google Scholar
• Panchal RG, Ruthel G, Kenny TA, Kallstrom GH, Lane D, Li L, Bavari S, Aman MJ. In vivo oligomerization and raft localization of Ebola virus protein VP40 during vesicular budding. Proc Natl Acad Sci USA 2003; 100: 15936–15941
   PubMed Web of Science ®Google Scholar
• Harder T, Simmons K. Caveolae, DIGs and the dinamic of sphingolipid-cholesterol microdomains. Curr Opin Cell Biol 1997; 9: 534–542
   PubMed Web of Science ®Google Scholar
• Brown DA, London E. Structure and function of sphingolipid- and cholesterol-rich membrane rafts. J Biol Chem 2000; 275: 17221–17224
   PubMed Web of Science ®Google Scholar
• Pralle A, Keller P, Florin EL, Simmons K, Horber JK. Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells. J Cell Biol 2000; 148: 997–1008
   PubMed Web of Science ®Google Scholar
• Laude AJ, Prior IA. Plasma membrane microdomains: Organization, function and trafficking. Mol Memb Biol 2004; 21: 193–205
   PubMed Web of Science ®Google Scholar
• Janes PW, Ley SC, Magee AI, Kabouridis PS. The role of lipid rafts in T cell antigen receptor (TCR) signalling. Semin Immunol 2000; 12: 23–24
   PubMed Web of Science ®Google Scholar
• Drevot P, Langlet C, Guo XJ, Bernard AM, Colard O, Chauvin JP, Lasserre R, He HT. TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts. EMBO J 2002; 15: 1899–1908
   Google Scholar
• Viola A. The amplification of TCR signaling by dynamic membrane microdomains. Trends Immunol 2001; 22: 322–327
   PubMed Web of Science ®Google Scholar
• Gupta N, DeFranco AL. Visualizing lipid rafts dynamics and early signalling events during antigen receptor-mediated B-lymphocyte activation. Mol Biol Cell 2003; 14: 432444
   Google Scholar
• Cheng PC, Brown BK, Song W, Pierce SK. Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signaling. J Immunol 2001; 166: 3693–3701
   PubMedGoogle Scholar
• Marmor MD, Julius M. Role for lipid rafts in regulating IL-2R signalling. Blood 2001; 98: 1489–497
   PubMedGoogle Scholar
• Roepstorff K, Thomsem P, Sandvig K, van Deurs B. Secuestration of EGF receptors in non-caveolar lipid rafts inhibits ligand binding. J Biol Chem 2000; 277: 18954–18960
   Google Scholar
• Liu P, Ying Y, Anderson RGW. Platelet-derived growth factor activates mitogen-activated protein kinase in isolated caveolae. Proc Natl Acad Sci USA 1997; 94: 13666–13670
   PubMedGoogle Scholar
• Davy A, Feuerstein C, Robbins SM. Signalling within a caveolae-like microdomain in human neuroblastoma cells in response to fibroblast growth factor. J Neurochem 2000; 74: 676–683
   PubMedGoogle Scholar
• Gustavsson J, Parpal S, Karlsson M, Ramsing C, Thorn H, Borg M, Lindroth M, Holmgren PK, Magnusson KE, Stralfors P. Localization of the insulin receptor in caveolae of adipocyte plasma membrane. FASEB J 1999; 13: 1961–1971
   PubMed Web of Science ®Google Scholar
• Piñeiro A, Cordero OJ, Nogueira M. Fifteen years of prothymosin alpha: contradictory past and new horizons. Peptides 2000; 9: 1433–1446
   Google Scholar
• Trumbore MW, Berger SL. Prothymosin a is a nonspecific facilitator of nuclear processes: Studies of Run-on transcription. Protein Expr Purif 2000; 20: 414–420
   PubMedGoogle Scholar
• Jiang X, Kim HE, Shu H, Zhao Y, Zhang H, Kofron J, Donnelly J, Burns D, Ng SC, Rosenberg S, Wang X. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science 2003; 299: 223–226
   PubMed Web of Science ®Google Scholar
• Papanastasiou M, Baxevanis CN, Papamichail M. Promotion of murine antitumor activity by prothymosin alpha treatment: I Introduction of tumoricidal peritoneal cells producing high levels of tumour necrosis factor. Cancer Immunol Immunother 1992; 35: 145–150
   PubMedGoogle Scholar
• Baxevanis CN, Gritzapis AD, Spanakos G, Tsitsilonis OE, Papamichail M. Induction of tumor-specific T lymphocyte responses in vivo by prothymosin alpha. Cancer Immunol Immunother 1995; 40: 410–418
   PubMedGoogle Scholar
• Baxevanis CN, Frilingos S, Reclos GJ, Arsenis P, Katsiyiannis A, Anastasopoulos E, Seferiadis K, Tsolas D, Papamichail M. Enhancement of human T lymphocyte function by prothymosin alpha: increased production of interleukin-2 and expression of interleukin-2 receptors on normal human peripheral blood T lymphocytes. Immunopharmacol Immunotoxicol 1990; 12: 595–617
   PubMed Web of Science ®Google Scholar
• Baxevanis CN, Reclos GJ, Papamichail M, Tsokos GC. Prothymosin alpha restores the depressed autologous and allogeneic mixed lymphocyte responses in patients with systemic lupus erythematosus. Immunopharmacol Immunotoxicol 1987; 9: 429–440
   PubMed Web of Science ®Google Scholar
• Baxevanis CN, Spanakos G, Voutsas IF, Gritzapis AD, Tsitsilonis OE, Mamalaki A, Papamichail M. Increased generation of autologous tumor-reactive lymphocytes by anti-CD3 monoclonal antibody and prothymosin alpha. Cancer Immunol Immunother 1999; 48: 71–84
   PubMedGoogle Scholar
• Cordero OJ, Sarandeses CS, Lopez JL, Cancio E, Regueiro BJ, Nogueira M. Prothymosin alpha enhances interleukin-2 receptor expression in normal human T-lymphocytes. Int J Immunopharmacol 1991; 13: 1059–1065
   PubMed Web of Science ®Google Scholar
• Cordero OJ, Sarandeses CS, Lopez JL, Nogueira M. Prothymosin alpha enhances human natural killer cell cytotoxicity: Role in mediating signals for NK activity. Lymphokine Cytokine Res 1992; 11: 277–285
   PubMedGoogle Scholar
• Cordero OJ, Sarandeses CS, Lopez-Rodriguez JL, Nogueira M. The presence and cytotoxicity of CD16+ CD2- subset from PBL and NK cells in long-term IL-2 cultures enhanced by Prothymosin alpha. Immunopharmacology 1995; 29: 215–223
   PubMedGoogle Scholar
• Lopez-Rodriguez JL, Cordero OJ, Sarandeses CS, Viñuela J, Nogueira M. Interleukin-2 killer cells: In vitro evaluation of combination with prothymosin alpha. Lymphokine Cytokine Res 1994; 13: 175–182
   PubMedGoogle Scholar
• Lopez JL, Czarnecki J, Cordero OJ, Nogueira M. Enhancement of cytoskeletal polarisation of NK cells upon conjugation with target cells by prothymosin alpha. Int J Thymol 1995; 3: 296–303
   Google Scholar
• Eckert K, Grunberg E, Garbin F, Maurer HR. Preclinical studies with prothymosin alpha 1 on mononuclear cells from tumour patients. Int J Immunopharmacol 1997; 19: 493–500
   PubMedGoogle Scholar
• Eckert K, Grunberg E, Immenschuh P, Garbin F, Kreuser ED, Maurer HR. Interleukin-2 activated killer cell activity in colorectal tumor patients: Evaluation of in vitro effects by prothymosin alpha 1. J Cancer Res Clin Oncol 1997; 123: 420–428
   PubMed Web of Science ®Google Scholar
• Cordero OJ, Sarandeses CS, Nogueira M. Prothymosin alpha receptors on peripheral blood mononuclear cells. FEBS Letters 1994; 341: 23–27
   PubMed Web of Science ®Google Scholar
• Cordero OJ, Sarandeses CS, Nogueira M. Prothymosin a receptors on lymphocytes. J Interferon Cytokine Res 1995; 15: 731–737
   PubMedGoogle Scholar
• Cordero OJ, Sarandeses CS, Nogueira M. Binding of 125I-prothymosin alpha to lymphoblasts through the non-thymosin alpha-1 sequence. Life Science 1996; 58: 1757–1770
   PubMedGoogle Scholar
• Piñeiro A, Bugía B, Arias MP, Cordero OJ, Nogueira M. Identification of receptors for Prothymosin a on human lymphocytes. Biol Chem 2001; 382: 1473–1482
   PubMedGoogle Scholar
• Ilangumaran S, Hoessli DC. Effects of cholesterol depletion by ciclodextrin on the sphingolipid microdomains of the plasma membrane. Biochem J 1998; 335: 433–440
   PubMedGoogle Scholar
• Ilangumaran S, Briol A, Hoessli DC. Distinct interactions among GPI-anchored, transmembrane and membrane associated intracellular proteins, and sphingolipids in lymphocyte and endothelial cell plasma membranes. Biochim Biophys Acta 1997; 1328: 27–36
   Google Scholar
• Ilangumaran S, Arni S, van Echten-Deckert G, Borish B, Hoessli DC. Microdomain-dependent regulation of lck and Fyn protein-tyrosine kinases in T-lymphocyte plasma membranes. Mol Biol Cell 1999; 10: 891–905
   PubMedGoogle Scholar
• Janes PW, Ley SC, Magee AI. Aggregation of lipid rafts accompanies signalling via the T cell antigen receptor. J Cell Biol 1999; 147: 447–461
   PubMed Web of Science ®Google Scholar
• Cheng PC, Dykstra ML, Mitchell RN, Pierce SK. A role for lipid rafts in B cell antigen receptor signaling and antigen targeting. J Exp Medicine 1999; 190: 1549–1560
   PubMed Web of Science ®Google Scholar
• Salgado FJ, Lojo J, Alonso-Lebrero JL, Lluis C, Franco R, Cordero OJ, Nogueira M. A role for interleukin-12 in the regulation of T cell plasma membrane compartmentation. J Biol Chem 2003; 278: 24849–24857
   PubMedGoogle Scholar
• Hanada KM, Nishijima Y, Akamasatu Y, Pagano RE. Both sphingolipids and cholesterol participate in the detergent insolubility of alkaline phosphatase, a glycosylphosphatilinositol-anchored protein, in mammalian membranes. J Biol Chem 1995; 270: 6254–6260
   PubMedGoogle Scholar
• Ostermeyer AG, Beckrich BT, Ivarson KA, Grove KE, Brown DA. Glycosphingolipids are not essential for formation of detergent-resistant membrane rafts in melanoma cells MβCD does not affect cell surface transport of a GPI-anchored protein. J Biol Chem 1999; 274: 34459–34466
   PubMedGoogle Scholar
• Magee AI, Parmryd I. Detergent-resistant membranes and the protein composition of lipid rafts. Genome Biol 2003; 4: 234–237
   PubMed Web of Science ®Google Scholar
• Cuortoy PJ, Quintart J, Baudhuin P. Shift of equilibrium density induced by 3,3′-diaminobenzidine cytochemistry: a new procedure for the analysis and purification of peroxidase-containing organelles. J Cell Biol 1984; 98: 870–878
   PubMedGoogle Scholar
• Taniguchi T, Minami Y. The IL-2/IL-2 receptor system: A current overview. Cell 1993; 73: 5–8
   PubMed Web of Science ®Google Scholar
• Cerneus DP, Ueffing E, Posthuma G, Strous GJ, van der Ende A. Detergent insolubility of alkaline phosphatase during biosynthetic transport and endocytosis Role of cholesterol. J Biol Chem 1993; 268: 3150–3155
   PubMedGoogle Scholar
• Schroeder R, London E, Brown D. Interactions between satured acyl chains confer detergent resistance to lipids and glycophosphatidylinositol-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behaviour. Proc Natl Acad Sci USA 1994; 91: 12310–12334
   Google Scholar
• Ahmed SN, Brown DA, London E. On the origin of sphingolipid cholesterol-rich detergent-insoluble cell membranes: Physiological concentrations of cholesterol and sphingolipid induce formation of a detergent insoluble, liquid ordered phase in model membranes. Biochemistry 1997; 36: 10944–10953
   PubMed Web of Science ®Google Scholar
• Friedrichson T, Kurzchalia T. Microdomains of GPI-anchored proteins in living cells revealed by cross-linking. Nature 1998; 394: 802–805
   PubMed Web of Science ®Google Scholar
• Varma R, Mayor S. GPI-anchored proteins are organized in submicron domains at the cell surface. Nature 1998; 394: 798–801
   PubMed Web of Science ®Google Scholar
• Hooper NM. Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae. Mol Memb Biol 1999; 16: 145–156
   PubMed Web of Science ®Google Scholar
• Spiegel S, Kassis M, Wilchek M, Fishman PH. Direct visualization of redistribution and capping of fluorescent gangliosides on lymphocytes. J Cell Biol 1984; 99: 1575–1581
   PubMedGoogle Scholar
• Harder T, Scheifelle P, Verkade P, Simmons K. Lipid domain structure revealed by patching of membrane components. J Cell Biol 1998; 141: 929–942
   PubMed Web of Science ®Google Scholar