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Stress
The International Journal on the Biology of Stress
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Short Communication

Reduced levels of the endocannabinoid arachidonylethanolamide (AEA) in hair in patients with borderline personality disorder – a pilot study

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Pages 366-369 | Received 13 Dec 2017, Accepted 06 Mar 2018, Published online: 16 Mar 2018

References

  • Bandelow, B., Baldwin, D., Abelli, M., Bolea-Alamanac, B., Bourin, M., Chamberlain, S.R., &Cinosi, E. (2017). Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition. World Journal of Biological Psychiatry, 18, 162–214. doi:10.1080/15622975.2016.1190867.
  • Bedse, G., Hartley, N.D., Neale, E., Gaulden, A.D., Patrick, T.A., Kingsley, P.J., et al. (2017). Functional redundancy between canonical endocannabinoid signaling systems in the modulation of anxiety. Biological Psychiatry, 82, 488–499. doi:10.1016/j.biopsych.2017.03.002.
  • Bluett, R.J., Baldi, R., Haymer, A., Gaulden, A.D., Hartley, N.D., Parrish, W.P., et al. (2017). Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. Nature Communications, 8, 14782. doi:10.1038/ncomms14782.
  • Bosch-Bouju, C., Larrieu, T., Linders, L., Manzoni, O.J., & Laye, S. (2016). Endocannabinoid-mediated plasticity in nucleus accumbens controls vulnerability to anxiety after social defeat stress. Cell Reports, 16, 1237–1242. doi:10.1016/j.celrep.2016.06.082.
  • Cattane, N., Rossi, R., Lanfredi, M., & Cattaneo, A. (2017). Borderline personality disorder and childhood trauma: exploring the affected biological systems and mechanisms. BMC Psychiatry, 17, 221. doi:10.1186/s12888-017-1383-2.
  • Dettenborn, L., Kirschbaum, C., Gao, W., Spitzer, C., Roepke, S., Otte, C., et al. (2016). Increased hair testosterone but unaltered hair cortisol in female patients with borderline personality disorder. Psychoneuroendocrinology, 71, 176–179. doi:10.1016/j.psyneuen.2016.05.026.
  • Hill, M.N., Bierer, L.M., Makotkine, I., Golier, J.A., Galea, S., McEwen, B.S., et al. (2013). Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. Psychoneuroendocrinology, 38, 2952–2961. doi:10.1016/j.psyneuen.2013.08.004.
  • Hill, M.N., Campolongo, P., Yehuda, R., & Patel, S. (2018). Integrating endocannabinoid signaling and cannabinoids into the biology and treatment of posttraumatic stress disorder. Neuropsychopharmacology, 43, 80–107. doi:10.1038/npp.2017.162.
  • Hillard, C.J. (2018). Circulating endocannabinoids: From whence do they come and where are they going? Neuropsychopharmacology, 43, 155–177. doi:10.1038/npp.2017.130.
  • Hillard, C.J., & Liu, Q.S. (2014). Endocannabinoid signaling in the etiology and treatment of major depressive illness. Current Pharmaceutical Design, 20, 3795–3811.
  • Katona, I., & Freund, T.F. (2012). Multiple functions of endocannabinoid signaling in the brain. Annual Review of Neuroscience, 35, 529–558. doi:10.1146/annurev-neuro-062111-150420.
  • Kirtley, O.J., O'Carroll, R.E., & O'Connor, R.C. (2015). The role of endogenous opioids in non-suicidal self-injurious behavior: methodological challenges. Neuroscience Biobehavioral Reviews, 48, 186–189. doi:10.1016/j.neubiorev.2014.11.007.
  • Krause-Utz, A., Winter, D., Niedtfeld, I., & Schmahl, C. (2014). The latest neuroimaging findings in borderline personality disorder. Current Psychiatry Reports, 16, 438. doi:10.1007/s11920-014-0438-z.
  • Krumbholz, A., Anielski, P., Reisch, N., Schelling, G., & Thieme, D. (2013). Diagnostic value of concentration profiles of glucocorticosteroids and endocannabinoids in hair. Therapeutic Drug Monitoring, 35, 600–607. doi:10.1097/FTD.0b013e3182953e43.
  • Mechoulam, R., & Parker, L.A. (2013). The endocannabinoid system and the brain. Annual Review of Psychology, 64, 21–47. doi:10.1146/annurev-psych-113011-143739.
  • Neumeister, A., Normandin, M.D., Pietrzak, R.H., Piomelli, D., Zheng, M.Q., Gujarro-Anton, A., et al. (2013). Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study. Molecular Psychiatry, 18, 1034–1040. doi:10.1038/mp.2013.61.
  • Riebe, C.J., & Wotjak, C.T. (2011). Endocannabinoids and stress. Stress (Amsterdam, Netherlands), 14, 384–397. doi:10.3109/10253890.2011.586753.
  • Schaefer, C., Enning, F., Mueller, J.K., Bumb, J.M., Rohleder, C., Odorfer, T.M., et al. (2014). Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. European Archives of Psychiatry and Clinical Neuroscience, 264, 459–463. doi:10.1007/s00406-013-0470-8.
  • Wilker, S., Pfeiffer, A., Elbert, T., Ovuga, E., Karabatsiakis, A., Krumbholz, A., et al. (2016). Endocannabinoid concentrations in hair are associated with PTSD symptom severity. Psychoneuroendocrinology, 67, 198–206. doi:10.1016/j.psyneuen.2016.02.010.
  • Wingenfeld, K., & Wolf, O.T. (2015). Effects of cortisol on cognition in major depressive disorder, posttraumatic stress disorder and borderline personality disorder – 2014 Curt Richter Award Winner. Psychoneuroendocrinology, 51, 282–295. doi:10.1016/j.psyneuen.2014.10.009.

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