Dietary fiber, inulin, and oligofructose: A review comparing their physiological effects

References

• Trowell , H. , Southgate , D. A. , Wolever , T. M. S. , Leeds , A. R. , Gassul , M. A. and Jenkins , D. J. A. 1976 . Dietary fibre redefined . Lancet , May 1 : 967
   Google Scholar
• Southgate , D. A. T. 1982 . “ Definitions and terminology of dietary fibre ” . In Dietary Fibre in Health and Disease , Edited by: Vahouny , G. V. and Kritchevsky , D. 1 New York : Plenum Press .
   Google Scholar
• Cummings , J. H. 1978 . Nutritional implications of dietary fibre . Am. J. Clin. Nutr. , 31 : 821
   Google Scholar
• Prosky , L. , Asp , N. G. , Furda , I. , Devries , J. W. and Schweizer , I. F. 1984 . Determination of total dietary fibre in foods, food product and total diets: interlab‐oratory study . J. Assoc. Off. Anal. Chem. , 67 : 1044
   Google Scholar
• Anderson , J. W. and Bridges , S. R. 1988 . Dietary fibre content of selected foods . Am. J. Clin. Nutr. , 47 : 440
   PubMed Web of Science ®Google Scholar
• Englyst , H. N. , Cummings , J. H. and Wood , R. 1987 . Determination of dietary fibre in cereals and cereal products. Collaborative trials. II. Study of modified Englyst procedure . J. Assoc. Public Analysts , 25 : 59
   Google Scholar
• Englyst , H. N. , Bingham , S. A. , Runswick , S. A. , Collinson , E. and Cummings , J. H. 1988 . Dietary fibre (non‐starch polysaceharides) in fruit, vegetable and nuts . J. Hum. Nutr. Diet. , 1 : 247
   Google Scholar
• Asp , N. G. 1987 . Definition and analysis of dietary fibre . Stand. J. Gastroenterol. , 22 (Suppl. 129) : 16
   Google Scholar
• Asp , N. G. 1990 . “ Raw materials naturally rich in fibre versus fibre concentrates/isolales in food production ” . In Dietary Fibre: Chemical and Biological Aspects , Edited by: Southgate , D. A. T. , Waldron , K. , Johnson , I. T. and Fenwick , G. R. Vol. 83 , 327 Royal Soc. Chem. Special Publ. .
   Google Scholar
• Marlett , J. A. . Dietary fibre, definition and determination . Proc. Kellogg's Int. Sxmp. Dietary Fibre . Edited by: Chen , S. C. pp. 4 Tokyo : Center Academic Publications .
   Google Scholar
• Eastwood , M. 1987 . Physiological properties of dietary fibre . Mol. Aspects Med. , 9 : 31
   Google Scholar
• Kritchevsky , D. 1988 . Dietary fibre . Annu. Rev. Nutr. , 8 : 301
   PubMed Web of Science ®Google Scholar
• Cummings , J. H. 1984 . Microbial digestion of complex carbohydrates in man . Proc. Nutr. Soc. , 43 : 35
   PubMed Web of Science ®Google Scholar
• Cummings , J. H. 1986 . The role of carbohydrates in lower gut function . Nutr. Rev. , 44 : 50
   PubMed Web of Science ®Google Scholar
• Roehrig , K. L. 1988 . The physiological effects of dietary fibre, a review . Food Hydrocolloids , 2 : 1
   Web of Science ®Google Scholar
• Grant‐Thompson , W. 1989 . “ The fibre story ” . In Gut Reactions, Understanding Symptoms in the Digestive Tract , 59 New York : Plenum Press .
   Google Scholar
• Nuovo , J. 1989 . Use of dietary fibre to lower cholesterol . AFP , 39 : 137
   Google Scholar
• Pilch , S. M. , ed. 1987 . Physiological Effects and Health Consequences of Dietary Fibre , Bethesda, MD : Life Sciences Research Office, Fed. Am. Soc. Exp. Biol. .
   Google Scholar
• Rockway , S. W. , Brannon , P. M. and Weber , C. W. 1987 . Bioavailability of copper bound to dietary fibre in mice and rats . J. Food Sci. , 52 : 1423
   Google Scholar
• Goodlab , R. A. , Lenton , W. , Ghatei , M. A. , Adrian , T. E. , Bloom , S. R. and Wright , N. A. 1987 . Effects of an elemental diet, inert bulk and different types of dietary fibre on the response of the intestinal epithelium to refeeding in the rat and relationship to plasma gastrin, enteroglucagon, and PYY concentrations . Gut. , 28 : 172
   Google Scholar
• Anderson , J. W. 1985 . Physiological and metabolic effects of dietary fibre . Fed. Proc. , 44 : 2902
   PubMedGoogle Scholar
• Tadesse , K. 1986 . The effect of dietary fibre isolates on gastric secretion, acidity and emptying . Br. J. Nutr. , 55 : 507
   Google Scholar
• Holt , S. , Heading , R. C. , Carter , D. C. , Prescott , L. F. and Tothill , P. 1979 . Effect of gel fibre on gastric emptying and absorption of glucose and paracetamol . Lancet , 1 : 636
   PubMed Web of Science ®Google Scholar
• Wilmshurst , P. and Crawley , J. C. W. 1980 . The measurement of gastric transit time in obese subjects using 24Na and effects of energy content and guar gum on gastric emptying and satiety . Br. J. Nutr. , 41 : 1
   Google Scholar
• Leeds , A. R. , Ralphs , D. N. L. , Ebied , F. , Metz , G. and Dihvari , J. P. 1981 . Pectin and the dumping syndrome: reduction of symptoms and plasma volume changes . Lancet , 1 : 1075
   PubMed Web of Science ®Google Scholar
• Leeds , A. R. 1982 . “ Modification of intestinal absorption by dietary fibre and fibre components ” . In Dietary Fiber in Health and Disease , Edited by: Vahouny , G. V. and Kritchevsky , D. 53 New York : Plenum Press .
   Google Scholar
• Schwarts , J. E. , Levine , R. A. , Singh , A. , Scheidecher , J. R. and Track , W. S. 1982 . Sustained pectin ingestion delays gastric emptying . Gastroenterology , 83 : 812
   Google Scholar
• Tinker , L. F. and Schneeman , B. O. 1989 . The effect of guar gum or wheat bran on the disappearance of 14C‐labelled starch from the rat gastro‐intestinal tract . J. Nutr. , 119 : 403
   PubMed Web of Science ®Google Scholar
• Blundell , J. E. and Burley , V. J. 1987 . Satiation, satiety and the action of fibre on food intake . Int. J. Obesity , 11 (Suppl. 1) : 9
   PubMedGoogle Scholar
• Burley , V. J. , Leeds , A. R. and Blundell , J. E. 1987 . The effect of high and low‐fibre breakfast on hunger satiety and food intake in a subsequent meal . Int. J. Obesity , 11 (Suppl. 1) : 87
   PubMedGoogle Scholar
• Jenkins , D. J. A. , Wolever , T. M. S. , Leeds , A. R. , Gassul , M. A. , Dilawari , J. , Goff , D. V. , Metz , G. L. and Alberti , K. G. 1978 . Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity . Br. Med. J. , 1 : 1392
   PubMed Web of Science ®Google Scholar
• Hamberg , O. , Rumessen , J. J. and Gudman‐Hoyer , E. 1989 . Reduced blood glucose response to pea fibre: comparisons with sugar beet fibre and wheat bran . Am. J. Clin. Nutr. , 50 : 324
   PubMed Web of Science ®Google Scholar
• Hamberg , O. , Rumessen , J. J. and Gudmand‐Hoyer , E. 1989 . Inhibition of starch absorption by dietary fibre . Scand. J. Gastroeuterol. , 24 : 103
   PubMed Web of Science ®Google Scholar
• Wahlqvist , M. L. 1987 . Dietary fibre and carbohydrate metabolism . Am. J. Clin. Nutr. , 45 : 1232
   Google Scholar
• Begin , F. , Vachon , C. , Jones , J. D. , Wood , P. J. and Savoie , L. 1989 . Effect of dietary fibres on glycaemia and insulinaemia and on gastrointestinal functions in rats . Can. J. Physiol. Pharmacol. , 67 : 1265
   PubMed Web of Science ®Google Scholar
• Vachon , C. , Jones , J. D. , Wood , P. J. and Savoie , J. 1988 . Concentration effects of soluble dietary fibres on postprandial glucose and insulin in the rat . Can. J. Physiol. Pharmacol. , 66 : 801
   PubMed Web of Science ®Google Scholar
• Anderson , J. W. 1982 . “ Dietary fibres and diabetes ” . In Dietary Fibre in Health and Disease , Edited by: Vahouny , G. V. and Kritchevsky , D. 151 New York : Plenum Press .
   Google Scholar
• Cherbut , C. 1988 . Fibres alimentaires et substances de charge: aspects physiologiques et nutritionnels . J. CPCIA , 27/12/88 Paris, France
   Google Scholar
• Eastwood , M. . Fibre in the gastro‐intestinal tract . Proc. Kellogg's Int. Symp. Dietary Fibre . Edited by: Chen , S. C. pp. 16 Tokyo : Center Academic Publications .
   Google Scholar
• Liu , Z. Q. , Chao , C. S. and Wu , H. W. 1989 . Investigation of the effect of a diet with wheat bran on the metabolic balances of Zn, Cu, Ca and Mg in diabetics . Chung‐Hua Nei‐K'o Tsa Chih , 28 : 741
   Google Scholar
• Torsdottir , I. , Alpstein , M. , Andersson , H. and Einursson , S. 1989 . Dietary guar gum effects on postprandial blood glucose, insulin and hydroxyproline in humans . J. Nutr. , 119 : 1925
   PubMed Web of Science ®Google Scholar
• Wisker , E. , Maltz , A. and Feldheim , W. 1988 . Metabolisable energy of diets low or high in dietary fibre from cereals when eaten by humans . J. Nutr. , 118 : 945
   PubMed Web of Science ®Google Scholar
• Schweizer , T. F. , Andersson , H. , Langkilde , A. M. , Reimann , S. and Torsdottir , I. 1990 . Nutrients excreted in ileostomy affluents after consumption of mixed diets with brans or potatoes. II. Starch, dietary fibre and sugars . Eur. J. Clin. Nutr. , 44 : 567
   Google Scholar
• Chun , W. , Bamba , T. and Hosoda , S. 1989 . Effect of pectin, a soluble dietary fibre, on functional and morphological parameters of the small intestine in rats . Digestion , 42 : 22
   PubMed Web of Science ®Google Scholar
• Dowling , R. H. 1982 . Small bowel adaptation and its regulation . Scand. J. Gastroenterol. , 17 (Suppl. 74) : 53
   Google Scholar
• Brown , R. C. , Kelleher , J. and Losowsky , M. S. 1979 . The effect of pectin on the structure and function of the rat small intestine . Br. J. Nutr. , 42 : 357
   PubMed Web of Science ®Google Scholar
• Dirks , P. and Freeman , H. J. 1987 . Effects of differing purified cellulose, pectin and hemicellulose fibre diets on mucosal morphology in the rat small and large intestine . Clin. Invest. Med. , 10 : 32
   PubMed Web of Science ®Google Scholar
• Jacobs , L. R. and Lupton , J. R. 1984 . Effect of dietary fibres on rat large bowel mucosal growth and cell proliferation . Am. J. Physiol. , 246 : G378
   PubMedGoogle Scholar
• Cassidy , M. M. , Lightfoot , F. G. , Grau , L. E. , Story , J. A. , Kritchevsky , D. and Vahouny , G. V. 1981 . Effect of chronic intake of dietary fibres on the ultrastructural topography of rat jejunum and colon: a scanning electron microscopy study . Am. J. Clin. Nutr. , 34 : 218
   PubMed Web of Science ®Google Scholar
• Ikegami , S. , Tsuchihashi , F. , Marada , H. , Tsuchihashi , N. , Nishide , E. and Innami , S. 1990 . Effect of viscous indigestible polysaccharides on pancreatic‐biliary secretion and digestive organs in rats . J. Nutr. , 120 : 353
   PubMed Web of Science ®Google Scholar
• Ebihara , K. and Schneeman , B. O. 1989 . Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibres in the small intestine of rats . J. Nutr. , 119 : 1100
   PubMed Web of Science ®Google Scholar
• Vahouny , G. V. 1982 . “ Dietary fibres and intestinal absorption of lipids ” . In Dietary Fibre in Health and Disease , Edited by: Vahouny , G. V. and Kritchevsky , D. 203 New York : Plenum Press .
   Google Scholar
• Gallaher , D. and Schneeman , B. O. 1986 . Intestinal interaction of bile acids, phospholipids, dietary fibres and cholestyramine . Am. J. Physiol. , 250 : G420
   Google Scholar
• Pomare , E. W. , Hileman , L. C. , Peters , S. and Fisher , A. 1987 . In vitro, studies with fibre components . Scand. J. Gastroenterol. , 22 (Suppl. 129) : 181
   Google Scholar
• Kritchevsky , D. 1987 . Dietary fibre and lipid metabolism . Int. J. Obesity , 11 (Suppl. 1) : 33
   PubMedGoogle Scholar
• Vahouny , G. V. , Roy , T. , Gallo , L. L. , Story , J. A. , Kritchevsky , D. and Cassidy , M. 1980 . Dietary fibres. Ill. Effects of chronic intake on cholesterol absorption and metabolism in the rat . Am. J. Clin. Nutr. , 33 : 2182
   PubMed Web of Science ®Google Scholar
• Vahouny , G. V. , Satchithanandam , S. , Chen , I. , Tepper , S. A. , Kritchevsky , D. , Lightfoot , F. G. and Cassidy , M. M. 1988 . Dietary fibre and intestinal adaptation: effects on lipid absorption and lymphatic transport in the rat . Am. J. Clin. Nutr. , 47 : 201
   PubMed Web of Science ®Google Scholar
• Chen , S. C. . Proc. Kellogg's Int. Symp. Dietary Fibre. . pp. 148 Tokyo : Center Academic Publications .
   Google Scholar
• Southgate , D. A. T. 1990 . “ Dietary fibre and health ” . In Dietary Fibre: Chemical and Biolgoical Aspects , Edited by: Southgale , D. A. T. , Waldron , K. , Johnson , I. T. and Fenwiek , G. R. 10 Royal Soc. Chem. Special Publ. .
   Google Scholar
• Harmuth‐Hoene , A. E. and Schelenz , R. 1980 . Effect of dietary fibre on mineral absorption in growing rats . J. Nutr. , 110 : 1774
   PubMed Web of Science ®Google Scholar
• Toma , R. B. and Curtis , D. J. 1986 . Dietary fibre: effect on mineral bioavailabilily . Food Technol. , 40 : 111
   Web of Science ®Google Scholar
• Balasubramanian , R. , Johnson , E. J. and Marlet , J. A. 1987 . Effect of wheat bran on bowel function and faecal calcium in older adults . J. Am. Coll. Nutr. , 6 : 199
   Google Scholar
• Behall , K. M. , Scholfield , D. J. , Lee , K. , Powell , A. S. and Moser , P. B. 1987 . Mineral balance in adult men: effect of four refined fibres . Am. J. Clin. Nutr. , 46 : 307
   PubMedGoogle Scholar
• Saito , Y. and Yoshita , K. 1987 . Effect of dietary fibre and protein level on calcium and magnesium absorption and availability in rats . Nippon Kasei Gakkaishi , 38 : 1047
   Google Scholar
• Vahouny , J. V. , Khalafi , R. , Satchithanandam , S. , Watkins , D. W. , Story , J. A. , Cassidy , M. M. and Kritchevsky , D. 1987 . Dietary fibre supplementation and faecal bile acids, neutral steroids and divalent cations in rats . J. Nutr. , 117 : 2009
   PubMed Web of Science ®Google Scholar
• Walker , A. R. P. 1987 . Dietary fibre and mineral metabolism . Mol. Aspects Med. , 9 : 69
   PubMedGoogle Scholar
• Demigné , C. , Levrat , M. A. and Remesy , C. 1989 . Effects of feeding fermentable carbohydrates on the caecal concentrations of minerals and their fluxes between the caecum and blood plasma in the rat . J. Nutr. , 119 : 1625
   PubMed Web of Science ®Google Scholar
• Kies , C. and Umoren , J. 1989 . Inhibitors of copper bio‐utilization: fibre, lead, phytate and tannins . Adv. Exp. Med. Biol. , 258 : 81
   PubMedGoogle Scholar
• Scholfield , D. J. , Behall , K. M. , Kelsay , J. L. , Prather , E. S. , Clark , W. M. , Reiser , S. and Canary , J. J. 1990 . The effects of natural dietary fibre from fruit and vegetables with oxalate from spinach on plasma minerals, lipids and other metabolites in man . Nutr. Res. , 10 : 367
   Google Scholar
• Satchithanandam , S. , Vargofcak‐Apker , M. , Calvert , R. S. , Leeds , A. R. and Cassidy , M. M. 1990 . Alteration of gastro‐intestinal mucin by fibre feeding in rats . J. Nutr. , 120 : 1179
   PubMed Web of Science ®Google Scholar
• Davies , I. R. , Johnson , I. T. and Livesey , G. 1987 . Food energy values of dietary fibre components and decreased deposition of body fat . Int. J. Ohesity , 11 (Suppl. I) : 101
   PubMedGoogle Scholar
• Schaus , E. E. , de Lumen , B. O. , Chow , F. I. , Reyes , P. and Omaye , S. T. 1985 . Bioavailability of vitamin E in rats fed graded levels of pectin . J. Nutr. , 115 : 265
   Google Scholar
• Schneeman , B. O. 1982 . “ Pancreatic and digestive function ” . In Dietary Fibre in Health and Disease , Edited by: Vahouny , G. V. and Kritchevsky , D. 73 New York : Plenum Press .
   Google Scholar
• Fuse , K. , Bamba , T. and Hosoda , S. 1989 . Effects of pectin on fatty acid and glucose absorption and on thickness of unstirred water layer in rat and human intestine . Dig. Dis. Sci. , 34 : 1109
   Google Scholar
• Schneeman , B. O. and Gallaher , D. 1980 . Changes in small‐intestinal digestive enzyme activity and bile acids with dietary cellulose in rats . J. Nutr. , 110 : 584
   PubMed Web of Science ®Google Scholar
• Mahapatra , S. C. , Bijlani , R. L. and Nayar , U. 1988 . Effect of cellulose and ispaghula husk on lasting blood glucose of developing rat . Int. J. Physiol. Pharmic. , 32 : 209
   Google Scholar
• Stephen , A. M. 1989 . The physiological effects of cellulose in the human large intestine . Anim. Food Sci. Technol. , 23 : 241
   Google Scholar
• Jacobs , L. R. and White , F. A. 1983 . Modulation of mucosal cell proliferation in the intestine of rats fed a wheat bran diet . Am. J. Clin. Nutr. , 37 : 945
   PubMed Web of Science ®Google Scholar
• Calvert , R. J. , Klurfeld , D. M. , Subramaniam , S. , Vahouny , G. V. and Kritchevsky , D. 1987 . Reduction of colonic carcinogenesis by wheat bran independent of faecal bile acid concentration . J. Natl. Cancer Inst. , 79 : 875
   PubMedGoogle Scholar
• Borel , P. , Lairon , D. , Senft , M. , Chautan , M. and Lafont , H. 1989 . Wheat bran and wheat germ: effect on digestion and intestinal absorption of dietary lipids in the rat . Am. J. Clin. Nutr. , 49 : 1192
   PubMed Web of Science ®Google Scholar
• Eastwood , M. A. , Brydon , W. G. and Anderson , D. M. W. 1986 . The effect of the polysaccharide composition and structure of dietary fibres on caecal fermentation and faecal excretion . Am. J. Nutr. , 44 : 51
   PubMed Web of Science ®Google Scholar
• Marcus , S. N. and Wehaton , K. W. 1986 . Effects of a new. concentrated wheat fibre preparation on intestinal transit, deoxycholic acid metabolism and the composition of bile . Gut , 27 : 893
   PubMed Web of Science ®Google Scholar
• Tomlin , J. and Read , N. W. 1988 . Comparison of the effects on colonic function caused by feeding rice bran and wheat bran . Eur. J. Clin. Nutr. , 42 : 857
   PubMed Web of Science ®Google Scholar
• Norman , D. F. L. , Ory , R. L. and Mod , R. R. 1987 . Binding of bile acids and trace minerals by soluble hemicellulose of rice . Food Technol. , Feb. : 86
   Google Scholar
• Indira , M. and Kurup , P. A. 1989 . Effects of neutral detergent fibre from blackgram (Phaseolus mungo) in rats and rabbits . J. Nutr. , 119 : 1246
   PubMed Web of Science ®Google Scholar
• Watters , K. and Blaisdell , P. 1989 . Reduction of gly‐caemic and lipid levels in db/db diabetic mice by Psyllium plant fibre . Diabetes , 38 : 1528
   Google Scholar
• Ghoos , Y. , Rutgeerts , P. , Vantrappen , G. , Hiele , M. and Schurmans , P. 1988 . The effect of long‐term fibre and starch intake by man on faecal bile acid excretion . Eur. J. Clin. Invest. , 18 : 128
   Google Scholar
• Anderson , J. W. , Spencer , D. B. , Hamilton , C. C. , Smith , S. F. , Tietyen , J. , Bryant , C. A. and Oeltgen , P. 1990 . Oat‐bran cereal lowers serum total and LDL cholesterol in hypercholesterolaemic men . Am. J. Clin. Nutr. , 52 : 495
   PubMed Web of Science ®Google Scholar
• Englyst , H. N. and Cummings , J. H. 1985 . Digestion of the polysaccharides of some cereal foods in the human small intestine . Am. J. Clin. Nutr. , 42 : 778
   PubMed Web of Science ®Google Scholar
• Cummings , J. H. 1982 . “ Consequences of the metabolism of fibre in the human large intestine ” . In Dietary Fibre in Health and Disease , Edited by: Vahouny , G. V. and Kritchevsky , D. 9 New York : Plenum Press .
   Google Scholar
• Hoverstad , T. and Bjorneklett , A. 1984 . Short‐chain fatty acids and bowel functions in man . Scand. J. Gastroenterol. , 19 : 1059
   PubMed Web of Science ®Google Scholar
• Walter , D. J. , Eastwood , M. A. , Brydon , W. G. and Elton , R. E. 1986 . An experimental design to study colonic fibre fermentation in the rat: duration of feeding . Br. J. Nutr. , 55 : 465
   PubMed Web of Science ®Google Scholar
• Livesey , G. , Davies , I. R. , Brown , J. C. , Faulks , R. M. and Southon , S. 1990 . Energy balance and energy values of α‐amylase (E.C.3.2.1.1) ‐resisiant maize and pea (Pisum sativum) starches in the rat . Br. J. Nutr. , 63 : 467
   PubMed Web of Science ®Google Scholar
• Hove , E. L. and King , S. 1979 . Effect of pectin and cellulose on growth, feed efficiency, and protein utilization, and their contribution to energy requirement and caecal VFA in rats . J. Nutr. , 109 : 1274
   PubMed Web of Science ®Google Scholar
• Demigné , C. , Remesy , C. and Rayssiguier , Y. 1980 . Effect of fermentable carbohydrates on volatile falls acids, ammonia and mineral absorption in rat caecum . Reprod. Nutr. Dev. , 20 : 1351
   PubMedGoogle Scholar
• Hsu , J. C. and Penner , M. H. 1989 . Influence of cellulose structure on its digestibility in the rat . J. Nutr. , 119 : 872
   Google Scholar
• Ornstein , M. H. and McLean‐Baird , I. 1987 . Dietary fibre and the colon . Mol. Aspects Med. , 9 : 41
   Google Scholar
• Edwards , C. A. , Tomlin , J. and Read , N. W. 1988 . Fibre and constipation, Br . J. Clin. Pract. , 42 : 26
   Google Scholar
• Tulung , B. , Remesy , C. and Demigné , C. 1987 . Specific effect of guar gum or gum arabic on adaptation of caecal digestion to high‐fibre diets in the rat . J. Nutr. , 117 : 1556
   PubMed Web of Science ®Google Scholar
• Edwards , C. A. 1987 . The mechanisms of action of dietary fibre in promoting colonic propulsion . Scand. J. Gastroenterol , 22 (Suppl. 129) : 97
   PubMed Web of Science ®Google Scholar
• Nyman , M. , Asp , N. G. , Cummings , J. and Wiggins , H. 1986 . Fermentation of dietary fibre in the intestinal tract: comparison between man and rat . Br. J. Nutr. , 55 : 487
   PubMed Web of Science ®Google Scholar
• Reddy , B. , Engle , A. , Simi , B. , O'Brien , L. T. , Barnard , R. J. , Pritikin , N. and Wynder , E. L. 1988 . Effect of low‐fat high‐carbohydrate, high‐fiber diet on fecal bile acids and neutral stools . Prev. Med. , 17 : 432
   PubMedGoogle Scholar
• Champ , M. , Barry , J. L. , Hoebler , C. and Delort‐Laval , J. 1989 . Digestion and fermentation pattern of various dietary fibre sources in the rat . Anim. Feed Sci. Technol. , 23 : 195
   Google Scholar
• Bagheri , M. and Debry , G. 1990 . Estimation de la consommation moyenne de fibres alimentaires en France . Ann. Nutr. Metab. , 34 : 69
   PubMedGoogle Scholar
• Mongeau , R. , Siddiqui , I. R. , Emery , J. and Brassard , R. 1990 . Effect of dietary fibre concentrated from celery, parsnip and rutabaga on intestinal function, serum cholesterol and blood glucose response in rats . J. Agric. Food. Chem. , 38 : 195
   Google Scholar
• Stephen , A. M. and Cummings , J. H. 1980 . The microbial contribution to human faecal mass . J. Med. Microbiol. , 60 : 811
   Google Scholar
• Jenkins , D. J. A. , Peterson , R. D. , Thorne , M. J. and Ferguson , P. W. 1987 . Wheat fibre and taxation: dose response and equilibration time . Am. J. Gastroenterol. , 82 : 1259
   Google Scholar
• Nyman , M. , Schweizer , T. F. , Tyren , S. , Reimann , S. and Asp , N. G. 1990 . Fermentation of vegetable fibre in the intestinal tract of rats and effects on faecal bulking and bile acid excretion . J. Nutr. , 120 : 459
   PubMed Web of Science ®Google Scholar
• Cummings , J. H. 1983 . Fermentation in the human large intestine: evidence and implications for health . Lancet , 1 : 1206
   PubMed Web of Science ®Google Scholar
• Miller , T. L. and Wolin , M. J. 1979 . Fermentation by saccharolytic intestinal bacteria . Am. J. Clin. Nutr. , 32 : 164
   PubMed Web of Science ®Google Scholar
• Mortensen , P. B. , Holtug , K. and Rasmussen , H. S. 1988 . Short‐chain fatty acid production from mono‐and disaccharides in a faecal incubation system: implications for colonic fermentation of dietary fibre in humans . J. Nutr. , 118 : 321
   PubMed Web of Science ®Google Scholar
• Zarling , E. J. and Ruchian , M. A. 1987 . Protein origin of the volatile fatty acids isobutyrate and isovalerate in human stool . J. Lab. Clin. Med. , 109 : 566
   PubMed Web of Science ®Google Scholar
• Cheng , B. Q. , Trimble , R. T. , Illman , R. J. , Stone , B. A. and Topping , D. L. 1987 . Comparative effects of dietary wheat bran and its morphological components (aleurone and pericarp‐seed coat) on volatile fatty acid concentrations in the rat . Br. J. Nutr. , 57 : 69
   PubMed Web of Science ®Google Scholar
• Fleming , S. E. , Fitch , M. D. and Chansler , M. W. 1989 . High‐fibre diets: influence on characteristics of caecal digesta including short‐chain fatty acid concentration and pH . Am. J. Clin. Nutr. , 50 : 93
   PubMed Web of Science ®Google Scholar
• Rasmussen , H. S. , Holtug , K. , Andersen , J. R. , Krag , E. and Mortensen , P. B. 1987 . The influence of ispaghula husk and lactulose on the in vivo and the in vitro production capacity of short‐chain fatty acids in humans . Scand. J. Gastroenterol. , 22 : 406
   PubMed Web of Science ®Google Scholar
• Mitchell , B. L. , Lawson , M. J. , Davies , M. , Kerr‐Grant , A. , Roediger , W. E. W. , Illman , R. J. and Topping , D. L. 1985 . Volatile fatty acids in the human intestine: studies in surgical patients . Nutr. Res. , 5 : 1089
   Web of Science ®Google Scholar
• Cummings , J. H. , Pomare , E. W. , Branch , W. J. , Naylor , C. P. E. and McFarlane , G. T. 1986 . Short‐chain fatty acids in human large intestine, portal hepatic and venous blood . Gut , 28 : 1221
   Google Scholar
• McBurney , M. I. , Thompson , L. U. , Cuff , D. J. and Jenkins , D. J. A. 1988 . Comparison of ileal effluents, dietary fibres and whole foods in predicting the physiological importance of colonic fermentation . Am. J. Gastroenterol. , 83 : 536
   PubMed Web of Science ®Google Scholar
• Roediger , W. E. W. 1980 . Role of anaerobic bacteria in the metabolism welfare of the colonic mucosa in man . Gut , 21 : 793
   PubMed Web of Science ®Google Scholar
• Cummings , J. H. 1981 . Short‐chain fatty acids in the human colon . Gut , 22 : 763
   PubMed Web of Science ®Google Scholar
• Hoverstad , T. 1986 . Studies of short‐chain fatty acid absorption in man . Scand. J. Gastroenterol. , 21 : 257
   PubMed Web of Science ®Google Scholar
• Vinee , A. , Down , P. F. and Murison , J. 1976 . Generation of ammonia from non‐urea sources in a faecal incubation system . Clin. Sci. Mol. Med. , 51 : 313
   Google Scholar
• Veilluex , B. G. and Rowland , I. 1981 . Stimulation of the rat intestinal ecosystem using a two‐stage continuous‐culture system . J. Gen. Microbiol. , 123 : 103
   Google Scholar
• Freter , R. , Stauffer , E. , Cleven , D. , Holdeman , L. V. and Moore , W. E. C. 1983 . Continuous‐flow cultures as in vitro models for the ecology of large intestinal flora . Infect. Immun. , 39 : 666
   PubMed Web of Science ®Google Scholar
• Edwards , C. A. , Duerden , B. I. and Read , N. W. 1985 . Metabolism of mixed human colonic bacteria in a continuous culture mimicking the human caecal contents . Gastroenterology , 88 : 1903
   PubMed Web of Science ®Google Scholar
• Costa , M. A. , Mehta , T. and Males , J. R. 1989 . Effects of dietary cellulose and psyllium husk on monkey colonic microbial metabolism in continuous culture . J. Nutr. , 119 : 979
   Google Scholar
• Costa , M. A. , Mehta , T. and Males , J. R. 1989 . Effects of dietary cellulose, psyllium husk and cholesterol level on faecal and colonic microbial metabolism in monkey . J. Nutr. , 119 : 986
   Google Scholar
• Gibson , G. R. , Cummings , J. H. and McFarlane , G. T. 1988 . Use of a three‐stage continuous‐culture system to study the effect of mucin on dissimilatory sulfate reduction and methanogenesis by mixed populations of human gut bacteria . Appl. Environ. Microbiol. , 54 : 2750
   PubMed Web of Science ®Google Scholar
• Wyatt , G. M. and Horn , N. 1988 . Fermentation of resistant food starches by human and rat intestinal bacteria . J. Sci. Food Agric. , 44 : 281
   Web of Science ®Google Scholar
• Brighenti , F. , Testolin , G. , Canzi , E. , Ferrari , A. , Wolever , T. M. S. , Ciappellano , S. , Porrini , M. and Simonetti , P. 1989 . Influence of long‐term feeding of different purified dietary fibres on the volatile fatty acid (VFA) profile. pH and fibre‐degrading activity of the caecal contents in rats . Nutr. Res. , 9 : 761
   Google Scholar
• Vince , A. J. , McNeil , N. I. , Wager , J. D. and Wrong , O. M. 1990 . The effect of lactulose. pectin arabinogalactan and cellulose on the production of organic acids and metabolism of ammonia by intestinal bacteria in a faecal incubation system . Br. J. Nutr. , 63 : 17
   PubMed Web of Science ®Google Scholar
• Stevens , B. J. H. , Selvendran , R. R. , Bayliss , C. E. and Turner , R. 1988 . Degradation of cell wall material of apple and wheat bran by human faecal bacteria in vitro . J. Sci. Food Agric. , 44 : 151
   Google Scholar
• Englyst , H. N. , Hay , S. and McFarlane , G. T. 1987 . Polysaccharide breakdown by mixed population of human faecal bacteria . FEMS Microbiol. Ecol. , 95 : 163
   Web of Science ®Google Scholar
• McBurney , M. I. and Thompson , L. U. 1990 . Fermentation characteristics of cereal brans and vegetable fibers . Nutr. Cancer , 13 : 271
   PubMed Web of Science ®Google Scholar
• Siragusa , R. J. , Cerda , J. J. , Baig , M. M. , Burgin , C. W. and Robbins , F. L. 1988 . Methanol production from the degradation of pectin by human colonic bacteria . Am. J. Clin. Nutr. , 47 : 848
   PubMed Web of Science ®Google Scholar
• Slade , A. P. , Wyatt , G. M. , Bayliss , C. E. and Waites , W. M. 1987 . Comparison of populations of human faecal bacteria before and after in vitro incubation with plant cell wall substrates . J. Appl. Bacterial. , 62 : 231
   PubMedGoogle Scholar
• Lupton , J. R. , Coder , D. M. and Jacobs , L. R. 1988 . Long‐term effects of fermentable fibres on rat colonic pH and epithelial cell cycle . J. Nutr. , 118 : 840
   PubMed Web of Science ®Google Scholar
• Hillman , L. , Peters , S. G. , Fisher , C. A. and Pomare , E. W. 1983 . Dietary effects of pectin, cellulose and lignin on stool pH, transit time and weight . Br. J. Nutr. , 50 : 189
   PubMed Web of Science ®Google Scholar
• Temple , N. J. and Basu , T. K. 1988 . Dietary fibre and the mouse colon: its influence on luminal pH. reducing activity and bile acid binding . Cancer Lett. , 41 : 111
   PubMedGoogle Scholar
• Lupton , J. R. and Marchant , L. J. 1989 . Independent effects of fibre and protein on colonic luminal ammonia concentration . J. Nutr. , 119 : 235
   PubMed Web of Science ®Google Scholar
• Remesy , C. and Demigné , C. 1989 . Specific effects of fermentable carbohydrates on blood urea flux and ammonia absorption in the rat caecum . J. Nutr. , 119 : 560
   PubMed Web of Science ®Google Scholar
• Sakata , T. and Yajima , T. 1984 . Influence of short‐chain fatty acids on the epithelial cell division of digestive tract . Q. J. Exp. Physiol. , 69 : 639
   PubMed Web of Science ®Google Scholar
• Sakata , T. 1986 . Effects of indigestible dietary bulk and short‐chain fatty acids on the tissue weight and epithelial cell proliferation rate of the digestive tract in rats . J. Nutr. Sci. Vitaminol. , 32 : 355
   PubMed Web of Science ®Google Scholar
• Sakata , T. 1987 . Stimulatory effect of short‐chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors . Br. J. Nutr. , 58 : 95
   PubMed Web of Science ®Google Scholar
• Lupton , J. R. , Coder , D. M. and Jacobs , L. R. 1985 . Influence of luminal pH on rat large bowel epithelial cell cycle . Am. J. Physiol. , 249 : G382
   Google Scholar
• Sakata , T. and Von Engelhardt , W. 1983 . Stimulatory effect of short‐chain fatty acids on the epithelial cell proliferation in rat large intestine . Comp. Biochem. Physiol. , 74A : 459
   Google Scholar
• Wyatt , G. M. , Horn , N. , Gee , J. M. and Johnson , I. T. 1988 . Intestinal microflora and gastro‐intestinal adaptation in the rat in response to non‐digestible dietary polysaccharides . Br. J. Nutr. , 60 : 198
   Google Scholar
• Judd , P. A. and Truswell , A. S. 1985 . The hypocholesterolaemic effects of pectins in rats . Br. J. Nutr. , 53 : 409
   PubMed Web of Science ®Google Scholar
• Anderson , J. W. 1987 . Dietary fibre, lipids and atherosclerosis . Am. J. Cardiol. , 60 : 17G
   PubMed Web of Science ®Google Scholar
• Kritchevsky , D. 1990 . “ Dietary fibre in lipid metabolism ” . In Dietary Fibre: Chemical and Biological Aspects , Edited by: Southgate , D. A. T. , Waldron , K. , Johnson , I. T. and Fenwick , G. R. 287 Royal Soc. Chem. Special Publ. .
   Google Scholar
• Story , J. A. and Thomas , J. N. 1982 . “ Modification of bile acid spectrum by dietary fibre ” . In Dietary Fibre Health and Disease , Edited by: Vahouny , G. V. and Kritchevsky , D. 193 New York : Plenum Press .
   Google Scholar
• Vigne , J. L. , Lairon , D. , Borel , P. , Portugal , H. , Pauli , A. M. , Hauton , J. C. and Lafont , H. 1987 . Effect of pectin, wheat bran and cellulose on scrum lipids and lipoproteins in rats fed on a low‐ or high‐fat diet . Br. J. Nutr. , 58 : 405
   PubMed Web of Science ®Google Scholar
• Kritchevsky , D. , Tepper , S. A. , Satchithanandam , S. , Cassidy , M. M. and Vahouny , G. 1988 . Dietary supplements: effects on serum and liver lipids and liver phospholipids composition in ruts . Lipids , 23 : 318
   PubMedGoogle Scholar
• Aritsuka , T. , Tanaka , K. and Kiriyama , S. 1989 . Effect of beet dietary fibre on lipid metabolism in rats fed a cholesterol‐free diet in comparison with pectin and cellulose . Nippon Eiyo Shokuryo Guhkusshi , 42 : 295
   Google Scholar
• Ide , T. , Horii , M. , Yamamoto , T. and Kawashima , K. 1990 . Contrasting effects of water‐soluble and water‐insoluble dietary fibres on bile acid conjugation and taurine metabolism in the rat . Lipids , 25 : 335
   Google Scholar
• Abraham , Z. D. and Mehta , T. 1988 . Three‐week psyllium‐husk supplementation: effect on plasma cholesterol concentrations, faecal steroid excretion, and carbohydrate absorption in men . Am. J. Clin. Nutr. , 47 : 67
   PubMed Web of Science ®Google Scholar
• Turner , P. R. , Tuomilehto , J. , Happonen , P. , La Ville , A. E. , Shaikh , M. and Lewis , B. 1990 . Metabolic studies on the hypolipidaemic effect of guar gum . Atherosclerosis , 81 : 145
   PubMed Web of Science ®Google Scholar
• Jenkins , D. J. A. , Hill , M. S. and Cummings , J. H. 1975 . Effect of wheat fibre on blood lipids, faecal steroid excretion and serum iron . Am. J. Clin. Nutr. , 28 : 1408
   PubMed Web of Science ®Google Scholar
• Arutyunova , M. B. , Garbuzov , A. G. , Kalinina , T. I. and Levatchev , M. M. 1989 . Influence of rations containing dietary fibre on the levels of total lipids and cholesterol in the blood and liver of rats under conditions of a 6.5 month experiment . Vopr. Pitan. , 6 : 47
   Google Scholar
• Demark‐Wahnefried , W. , Bowering , J. and Cohen , P. S. 1990 . Reduced serum cholesterol with dietary change using fat‐modified and oat bran suppl‐mented diet . J. Am. Diet. Assoc. , 90 : 223
   PubMed Web of Science ®Google Scholar
• Ikeda , I. , Tomari , Y. and Sugano , M. 1989 . Interrelated effects of dietary fibre and fat on lymphatic cholesterol and triglyceride absorption in rats . J. Nutr. , 119 : 1383
   PubMed Web of Science ®Google Scholar
• Hillman , L. C. , Peters , S. G. , Fisher , C. A. and Pomare , E. W. 1986 . Effects of the fibre components pectin, cellulose and lignin on bile salt metabolism and biliary lipid composition in man . Gut , 27 : 29
   PubMed Web of Science ®Google Scholar
• Anderson , J. W. and Gustafson , N. J. 1988 . Hypocholesterolaemic effects of oat and bean products . Am. J. Clin. Nutr. , 48 : 749
   PubMed Web of Science ®Google Scholar
• Anderson , I. H. , Levine , A. S. and Levitt , M. D. 1981 . Incomplete absorption of the carbohydrate in all‐purpose flour . N. Engl. J. Med. , 304 : 891
   PubMed Web of Science ®Google Scholar
• Stephen , A. M. , Haddad , A. C. and Phillips , S. F. 1983 . Passage of carbohydrate into the colon. Direct measurements in humans . Gastroenterology , 85 : 589
   PubMed Web of Science ®Google Scholar
• Bingham , S. A. and Cummings , J. H. . Dietary starch, non‐starch polysaccharides and large bowel cancer . Proc. Kellogg's Int. Symp. Dietary Fibre . Edited by: Chen , S. C. pp. 97 Tokyo : Center Academic Publications .
   Google Scholar
• Tsui , Y. , Yamamada , K. , Hosoya , N. and Moriuchi , S. 1986 . Digestion and absorption of sugars and sugar substitutes in rat small intestine . J. Nutr. Sci. Vitaminol. , 32 : 93
   Google Scholar
• Mazur , A. , Remesy , C. , Gueux , E. , Levrat , M. A. and Demigne , C. 1990 . Effects of diets rich in fermentable carbohydrates on plasma lipoprotein levels and on lipoprotein catabolism in rats . J. Nutr. , 120 : 1037
   PubMed Web of Science ®Google Scholar
• Nyman , M. and Asp , N. G. 1982 . Fermentation of dietary fibre components in the rat intestinal tract . Br. J. Nutr. , 47 : 357
   PubMed Web of Science ®Google Scholar
• Cummings , J. H. , Southgate , D. A. , Branch , W. J. , Wiggins , H. S. , Houston , H. , Jenkins , D. S. , Jivraj , T. and Hill , M. J. 1979 . The digestion of pectin in the human gut and its effect on absorption of calcium and large bowel function . Br. J. Nutr. , 41 : 477
   PubMed Web of Science ®Google Scholar
• Pomare , E. W. , Branch , W. J. and Cummings , J. H. 1985 . Carbohydrate fermentation in the human colon and its relation to acetate concentration in venous blood . J. Clin. Invest. , 75 : 1148
   Google Scholar
• Beck , B. , Villaume , C. , Bau , H. M. , Gariot , P. , Chayvialle , J. A. , Desalme , A. and Debry , G. 1986 . Long‐term influence of a wheat bran supplemented diet on secretion of gastro‐intestinal hormones and on nutrient absorption in healthy men . Hum. Nutr. Clin. Nutr. , 40C : 25
   Google Scholar
• Gallaher , D. D. and Franz , P. M. 1990 . Effects of corn oil and wheat brans on bile acid metabolism in rats . J. Nutr. , 120 : 1320
   PubMed Web of Science ®Google Scholar
• Anderson , J. W. and Bridges , S. R. 1981 . Plant fibre metabolites alter hepatic glucose and lipid metabolism . Diabetes , 30 (Suppl. 1) : 133A
   Google Scholar
• Stanley , J. C. and Newsholme , E. A. 1985 . The effect of dietary guar gum on the activities of some key enzymes of carbohydrate and lipid metabolism in mouse . Br. J. Nutr. , 53 : 215
   Google Scholar
• McNeil , N. I. , Cummings , J. H. and James , P. H. 1978 . Short‐chain fatty acid absorption by the human large intestine . Gut , 19 : 819
   PubMed Web of Science ®Google Scholar
• Demigné , C. , Yacoub , C. , Remesy , C. and Fafournoux , P. 1986 . Propionate and butyrate metabolism in rat or sheep hepatocytes . Biochim. Biophys. Acta , 875 : 535
   PubMed Web of Science ®Google Scholar
• Demigne , C. , Yacoub , C. and Remesy , C. 1986 . Effects of absorption of large amounts of volatile fatty acids on rat liver metabolism . J. Nutr. , 116 : 77
   Google Scholar
• Herrman , D. B. J. , Here , R. and Frohlich , J. 1985 . Role of gastro‐intestinal tract and liver in acetate metabolism in rat and man . Eur. J. Clin. Invest. , 15 : 221
   Google Scholar
• Buckley , B. M. and Williamson , D. H. 1977 . Origins of blood acetate in the rat . Biochem. J. , 166 : 539
   PubMed Web of Science ®Google Scholar
• Akaniji , A. O. , Peterson , D. B. , Humphreys , S. and Hockaday , D. R. 1989 . Change in plasma acetate levels in diabetic subjects on mixed high‐fibre diets . Am. J. Gastroenterol. , 84 : 1365
   Google Scholar
• Anderson , J. W. and Bridges , S. R. 1984 . Short‐chain fatty acid fermentation products and plant fibre affect glucose metabolism of isolated rat hepatocytes . Proc. Soc. Exp. Biol. Med. , 177 : 372
   PubMed Web of Science ®Google Scholar
• Imoto , S. and Namioka , S. 1983 . Acetate‐glucose relationship in growing pigs . J. Anim. Sci. , 56 : 867
   PubMed Web of Science ®Google Scholar
• Patel , D. G. and Singh , S. P. 1979 . Effect of ethanol and its metabolites on glucose‐mediated insulin release from isolated islets of rats . Metabolism , 28 : 85
   PubMed Web of Science ®Google Scholar
• Scheppach , W. , Wiggins , H. S. , Halliday , D. , Self , R. , Howard , J. , Branch , W. J. , Schrezenmeir , J. and Cummings , J. H. 1988 . Effect of gut‐derived acetate on glucose turnover in man . Clin. Sci. , 75 : 363
   Google Scholar
• Nomura , T. , Iguchi , A. , Sakamoto , N. and Harris , R. A. 1983 . Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis . Biochim. Biophys, Acta , 754 : 315
   Google Scholar
• Venter , C. S. , Vorster , H. H. and Cummings , J. H. 1990 . Effects of dietary propionate on carbohydrate and lipid metabolism in healthy volunteers . Am. J. Gastroenterol. , 85 : 549
   PubMed Web of Science ®Google Scholar
• Venter , C. S. , Vorster , H. H. and Van der Nest , D. G. 1990 . Comparison between physiological effects of konjac‐glucomannan and propionate in baboons fed “Western”; diets . J. Nutr. , 120 : 1046
   Google Scholar
• Crouse , J. R. , Gerson , D. , De Carli , L. M. and Lieber , S. 1968 . Role of acetate in the reduction of plasma free fatty acids produced by ethanol in man . J. Lipid Res. , 9 : 509
   PubMed Web of Science ®Google Scholar
• Nilsson , N. O. and Belfrage , P. 1978 . Effects of acetate, acetaldehyde and ethanol on lipolysis in isolated rat adipocytes . J. Lipid Res. , 19 : 737
   Google Scholar
• Chen , W. J. L. , Anderson , J. W. and Jennings , D. 1984 . Propionate may mediate the hypocholestero‐Iaemic effects of certain soluble plant fibres in cholesterol‐fed rats . Proc. Soc. Exp. Biol. Med. , 175 : 215
   PubMed Web of Science ®Google Scholar
• Bell , L. P. , Hectorn , K. J. , Reynolds , H. and Hunningha , K. E. 1990 . Cholesterol‐lowering effects of soluble‐fibre cereals as part of a prudent diet for patients with mild to moderate hypocholesterolaemia . Am. J. Clin. Nutr. , 52 : 1020
   PubMed Web of Science ®Google Scholar
• Kritchevsky , D. , Davidson , L. M. , Scott , D. A. , Van der Watt , J. J. and Mendelsohn , D. 1988 . Effects of dietary fibre in vervet monkeys fed “Western”; diets . Lipids , 23 : 164
   PubMedGoogle Scholar
• Bhattathiry , E. P. M. 1971 . Effects of polysaccharides on the biosynthesis of lipids in adult rats . Far East Med. J. , 7 : 187
   Google Scholar
• Kay , R. M. and Truswell , A. S. 1980 . “ Dietary fibre: effects on plasma and biliary lipids in man ” . In Medical Aspects of Dietary Fibre , Edited by: Spiller , G. A. and Kay , R. M. 153 New York : Plenum Press .
   Google Scholar
• Chen , W. J. L. and Anderson , J. W. 1979 . Effect of plant fibre in decreasing plasma total cholesterol and increasing high‐density lipoprotein cholesterol . Proc. Soc. Exp. Biol. Med. , 162 : 310
   PubMed Web of Science ®Google Scholar
• Gee , J. M. , Blackburn , N. A. and Johnson , I. T. 1983 . The influence of guar gum on intestinal cholesterol transport in the rat . Br. J. Nutr. , 50 : 215
   PubMed Web of Science ®Google Scholar
• Todd , P. A. , Benfield , P. and Goa , K. L. 1990 . Guar gum. A new review of its pharmacological properties, and use as dietary adjunct in hypercholesterolaemia . Drugs , 39 : 917
   PubMed Web of Science ®Google Scholar
• Muzaffar , M. , Bakhsh , R. , Khan , S. and Khan , S. 1989 . Effect of different dietary brans on lipid metabolism in male albino rats . Die Nahrung , 33 : 167
   Google Scholar
• Johnson , I. T. , Livesey , G. , Gee , J. M. , Brown , J. C. and Wortley , G. M. 1990 . The biological effects and digestible energy value of a sugar‐beet fibre preparation in the rat . Br. J. Nutr. , 64 : 187
   PubMed Web of Science ®Google Scholar
• Gariot , P. , Digy , J. R. , Genton , P. O. , Lambeat , D. , Bau , M. H. and Deby , G. 1986 . Long‐term effect of bran ingestion on lipid metabolism in healthy man . Ann. Nutr. Metabl. , 30 : 369
   Google Scholar
• Van Horn , L. , Liu , K. , Parker , D. , Emidy , L. , Liao , Y. , Giumetti and Stamler , J. 1986 . Serum lipid response to oat product intake with a fat‐modified diet . J. Am. Diet. Assoc. , 86 : 759
   PubMed Web of Science ®Google Scholar
• Van Horn , L. , Emidy , L. A. , Liu , K. , Liao , Y. , Ballew , C. , King , J. and Stamler , J. 1988 . Serum lipid response to fat‐modified oatmeal‐enhanced diet . Prev. Med. , 17 : 377
   PubMed Web of Science ®Google Scholar
• Lund , E. K. , Farleigh , C. A. and Johnson , I. T. 1990 . “ Do oats lower blood cholesterol? ” . In Dietary Fibre: Chemical and Biological Aspects , Edited by: Southgate , D. A. T. , Waldron , K. , Johnson , I. T. and Fenwick , G. R. 296 Royal Soc. Chem. Special Publ. .
   Google Scholar
• Topping , D. L. , Illman , R. J. , Dowling , K. and Trimble , R. P. 1990 . “ Mechanisms whereby fibre could lower plasma cholesterol ” . In Dietary Fibre: Chemical and Biological Aspects , Edited by: Southgate , D. A. T. , Waldron , K. , Johnson , I. T. and Fenwick , G. R. 300 Royal Soc. Chem. Special Publ. .
   Google Scholar
• Wicks , A. C. B. , Yeates , J. and Heaton , K. W. 1978 . Bran and bile: time course of changes in normal young man given a standard dose . Scand. J. Gastroenterol. , 13 : 289
   PubMed Web of Science ®Google Scholar
• Spiller , G. A. , Story , J. A. , Wong , L. G. , Nunes , J. D. , Alton , M. , Petro , M. S. , Furumoto , E. J. , Whittam , J. H. and Scala , J. 1986 . Effect of increasing levels of hard wheat fibre on faecal weight, minerals and steroids and gastro‐intestinal transit time in healthy young women . J. Nutr. , 116 : 778
   PubMed Web of Science ®Google Scholar
• Pomare , E. W. , Heaton , K. W. , Low‐Beer , T. S. and Espiner , H. J. 1976 . The effect of wheat bran upon bile salt metabolism and upon the lipid composition of bile in gallstone patients . Am. J. Dig. Dis. , 21 : 521
   PubMedGoogle Scholar
• Johnson , I. T. , Gee , J. M. and Brown , J. C. 1988 . Plasma enteroglucagon and small bowel cytokinetics in rats fed soluble non‐starch polysaccharides . Am. J. Clin. Nutr. , 47 : 1004
   PubMedGoogle Scholar
• Uttenthal , L. O. , Batt , R. M. , Carter , M. W. and Bloom , S. R. 1982 . Stimulation of DNA synthesis in cultured small intestine by partially purified enteroglucagon . Regul. Peptide , 3 : 844
   Google Scholar
• Miazza , B. M. , Al‐Mukhtar , M. Y. T. , Salmeron , M. , Ghatei , M. A. , Felce‐Dachez , M. , Filali , A. , Villet , R. , Wright , N. A. , Bloom , S. R. and Rambaud , J. C. 1985 . Hyperglucagonaemia and small‐intestinal mucosal growth after colonic perfusion of glucose in rats . Gut , 26 : 518
   Google Scholar
• Gee , J. M. and Johnson , I. T. 1990 . “ Effects of some soluble non‐starch polysaccharides on food intake, cell tumors and gastro‐intestinal peptide levels in the rat ” . In Dietary Fibre: Chemical and Biological Aspects , Edited by: Southgate , D. A. T. , Waldron , K. , Johnson , I. T. and Fenwich , G. R. 169 Royal Soc. Chem. Special Publ. .
   Google Scholar
• Johnson , I. T. 1990 . “ The biological effects of dietary fibre in the small intestine ” . In Dietary Fibre: Chemical and Biological Aspects , Edited by: Southgate , D. A. T. , Waldron , K. , Johnson , I. T. and Fenwick , G. R. 151 Royal Soc. Chem. Special Publ. .
   Google Scholar
• Kasper , H. , Rabast , U. , Fassl , H. and Fehle , F. 1979 . The effect of dietary fibre on the postprandial serum vitamin A concentration in man . Am. J. Clin. Nutr. , 32 : 1847
   PubMedGoogle Scholar
• Kesaniemi , V. A. , Tarpila , S. and Miettinen , T. A. 1990 . Low vs. high‐dietary fibre and serum, biliary, and faecal lipids in middle‐aged men . Am. J. Clin. Nutr. , 51 : 1007
   PubMed Web of Science ®Google Scholar
• Roberfroid , M. , Delzenne , N. and Preat , V. 1991 . Modulation of hepatocarcinogenesis . Annu. Rev. Pharmacol. Toxicol. , 31 : 163
   Google Scholar
• Reddy , B. S. 1985 . Nutritional aspects of colon cancer . Progr. Food Nutr. Sci. , 9 : 257
   PubMedGoogle Scholar
• Jacobs , L. R. 1986 . Modification of experimental colon carcinogenesis by dietary fibres . Adv. Exp. Med. Biol. , 206 : 105
   PubMedGoogle Scholar
• Jacobs , L. R. 1986 . Relationship between dietary fibre and cancer: metabolic, physiologic and cellular mechanisms . Proc. Soc. Exp. Biol. Med. , 183 : 299
   PubMedGoogle Scholar
• Kritchevsky , D. 1986 . “ Fat, calories and fibre ” . In Dietary Fat and Cancer , Edited by: Ip , C. L. , Bin , D. F. , Rogers , A. E. and Mettlin , C. 495 Alan R. Liss .
   Google Scholar
• Kritchevsky , D. 1986 . Diet, nutrition and cancer: the role of fibre . Cancer , 58 : 1830
   PubMed Web of Science ®Google Scholar
• Reddy , B. S. 1987 . Dietary fibre and colon cancer: animal model studies . Prev. Med. , 16 : 559
   PubMed Web of Science ®Google Scholar
• Wilpart , M. 1987 . “ Dietary fats and fibre and experimental colon carcinogenesis: a critical review of published evidences ” . In Causation and Prevention of Colorectal Cancer , Edited by: Faivre , J. and Hill , M. 85 Elsevier Science .
   Google Scholar
• Wilpart , M. and Roberfroid , M. 1987 . Intestinal carcinogenesis and dietary fibres: the influence of cellulose and fybogel chronically given after exposure to DMH . Nutr. Cancer , 10 : 39
   PubMedGoogle Scholar
• Jenkins , D. J. A. , Jenkins , A. L. , Rao , A. V. and Thompson , L. U. 1986 . Cancer risk: possible protective role of high‐fibre diets . Am. J. Gastroenterol. , 81 : 931
   PubMed Web of Science ®Google Scholar
• Burkitt , D. 1978 . Colonic‐rectal cancer: fibre and other dietary factors . Am. J. Clin. Nutr. , 31 : S58
   Google Scholar
• Nauss , K. M. , Jacobs , L. R. and Newberne , P. M. 1987 . Dietary fat and fibre: relationship to caloric intake, body growth, and colon tumorigenesis . Am. J. Clin. Nutr. , 45 : 243
   PubMed Web of Science ®Google Scholar
• Kaur , A. P. , Bhat , C. M. and Grewal , R. B. 1985 . Effects of cellulose incorporation in a low‐fibre diet on faecal excretion and digestibility of nutrients in adolescent girls . Nutr. Rep. Int. , 32 : 383
   Google Scholar
• Watanabe , K. , Reddy , B. S. , Weisburger , J. H. and Kritchevsky , D. 1979 . Effect of dietary alfalfa, pectin, and wheat bran on azoxymethane‐ or methylni‐trosourea‐induced colon carcinogenesis in F‐344 rats . J. Natl. Cancer Inst. , 63 : 142
   Google Scholar
• Cummings , J. H. , Hill , M. J. , Jenkins , D. J. , Pearson , J. R. and Wiggins , H. S. 1976 . Changes in faecal composition and colonic function due to cereal fibre . Am. J. Clin. Nutr. , 29 : 1468
   PubMed Web of Science ®Google Scholar
• Kritchevsky , D. 1990 . Fibre and cancer . Med. Oncol. Tumor Pharmacother. , 7 : 137
   PubMedGoogle Scholar
• Roberfroid , M. 1991 . Dietary modulation of experimental neoplastic development: role of fat and fibre content and caloric intake . Mutat. Res. , 259 : 351
   PubMed Web of Science ®Google Scholar
• Cummings , J. H. and Bingham , S. A. 1987 . Dietary fibre, fermentation and large bowel cancer . Cancer Surv. , 6 : 601
   PubMedGoogle Scholar
• Jacobs , L. R. 1980 . Fibre and colon cancer . GastroenteroL Clin. N. Am. , 17 : 747
   Google Scholar
• Mogadam , M. 1988 . Cancer and nutritional misconceptions: a perspective . Am. J. Gastroenterol. , 88 : 1346
   Google Scholar
• Newberne , P. M. and Conner , M. W. 1988 . Dietary Modifiers of Cancer, Nutrition, Growth and Cancer , 105 Alan R. Lis .
   Google Scholar
• Heilbrun , L. K. , Nomura , A. , Hankin , J. H. and Stemmerman , G. N. 1989 . Diet and colorectal cancer with special reference to fibre intake . Int. J. Cancer , 44 : 1
   PubMed Web of Science ®Google Scholar
• Trock , B. , Lanza , E. and Greenwald , P. 1990 . Dietary fibre, vegetables and colon cancer: critical review and meta‐analysis of the epidemiologic evidence . J. Natl. Cancer Inst. , 82 : 650
   PubMed Web of Science ®Google Scholar
• Carpita , N. C. , Kanabus , J. and Houlsley , T. L. 1989 . Linkage structure of fructans and fructan oligomers from Triticum aestivum and Festuca arundinacea leaves . J. Plant Physiol. , 134 : 162
   Google Scholar
• Phelps , C. F. 1965 . The physical properties of inulin solutions . Biochem. J. , 95 : 41
   PubMed Web of Science ®Google Scholar
• Nilsson , U. , Oste , R. , Jagerstad , M. and Birkhed , D. 1988 . Cereal fructans: in vitro and in vivo studies on availability in rats and humans . J. Nutr. , 118 : 1325
   PubMed Web of Science ®Google Scholar
• Nilsson , U. and Bjorck , I. 1988 . Availability of cereal fructans and inulin in the rat intestinal tract . J. Nutr. , 118 : 1482
   PubMed Web of Science ®Google Scholar
• Graham , H. and Aman , P. 1986 . Composition and digestion in the pig gastro‐intestinal tract of Jerusalem artichoke tubers . Food Chem. , 22 : 67
   Web of Science ®Google Scholar
• Stone‐Dorshow , T. and Levitt , M. D. 1987 . Gaseous response to ingestion of a poorly absorbed fructo‐oligosaccharide sweetener . Am. J. Clin. Nutr. , 46 : 61
   PubMed Web of Science ®Google Scholar
• Rumessen , J. J. , Bode , S. , Hamberg , O. and Hoyer , E. G. 1990 . Fructans of Jerusalem artichokes: intestinal transport, absorption, fermentation and influence on blood glucose, insulin and C peptide responses in healthy subjects . Am. J. Clin. Nutr. , 52 : 675
   PubMed Web of Science ®Google Scholar
• Hidaka , H. 1983 . Fructosyl oligosaccharides, a new material for dietary food. Attention to the improvement of intestinal bacteria balance and the effect of lowering cholesterol in blood . Kagaku to Seibutsu , 21 : 291
   Google Scholar
• Hidaka , H. , Eida , T. , Takizawa , T. , Tokunaga , T. and Tashiro , Y. 1986 . Effects of fructo‐oligosaccha‐rides on intestinal flora and human health . Bifidobacteria Microflora , 5 : 37
   Google Scholar
• Oku , T. , Tokunaga , T. and Hosoya , N. 1984 . Non‐digestibility of a new sweetener “Neosugar”; in the rat . J. Nutr. , 114 : 1574
   PubMed Web of Science ®Google Scholar
• Oku , T. and Tokunaga , T. . Improvement of metabolism by “Neosugar”;: effect of fructo‐oligosaccharides in rat intestine . Proc. 2nd Neosugar Res. Conf. Neosugar Res. Soc. . pp. 53 Meiji‐Seika Publ. .
   Google Scholar
• Ziesenitz , S. C. and Siebert , G. 1987 . In vitro assessment of nystose as a sugar substitute . J. Nutr. , 117 : 846
   Google Scholar
• Tokunaga , T. , Oku , T. and Hosoya , N. 1989 . Utilisation and excretion of a new sweetener, fructo‐oli‐gosaccharide (Neosugar) in rats . J. Nutr. , 119 : 553
   PubMed Web of Science ®Google Scholar
• Sanno , T. , Ishikawa , M. , Nozawa , Y. , Hoshi , K. and Someya , K. . Application of Neosugar P for diabetic subjects. The effect of Neosugar P on sugar tolerance . Proc. 2nd Neosugar Res. Conf., Neosugar Res. Soc. . pp. 29 Meiji‐Seika Publ. .
   Google Scholar
• Yamashita , K. , Kawai , K. and Itakura , M. 1984 . Effects of fructo‐oligosaccharides on blood glucose and serum lipids in diabetic subjects . Nutr. Res. , 4 : 961
   Web of Science ®Google Scholar
• Brichard , S. 1989 . “ Influence de Mesures Nutritionnelles sur l'homéostasie Glucidique due Rat Diabétique; Effets Bénéfiques des Fructo‐oligosaccharides et du Vanadium ” . UCL thesis
   Google Scholar
• Tokunaga , T. , Oku , T. and Hosoya , N. 1986 . Influence of chronic intake of new sweetener furcto‐oligosaccharide (Neosugar) on growth and gastro‐intestinal function of the rat . J. Nutr. Sci. Vitaminol. , 32 : 111
   PubMed Web of Science ®Google Scholar
• Okada , J. , Shimada , K. and Mitsuoka , T. . Neosugar as bifidobacteria‐proliferating substance . Proc. 2nd Neosugar Res. Conf., Neosugar Res. Soc. . pp. 69 Meiji‐Seika Publ. .
   Google Scholar
• Yazawa , K. , Imai , K. Tamura , Z. 1978 . Oligo‐saccharides and polysaccharides specifically utilisable by bifidobacteria . Chem. Pharm. Bull. , 26 (1) : 3306
   PubMed Web of Science ®Google Scholar
• Yazawa , K. and Tamura , Z. 1982 . Search for sugar sources for the selective increase of Bifidobacteria . Bifidobacteira Microflora , 1 : 39
   Google Scholar
• Hesson, personal communication
   Google Scholar
• Knudsen, personal communication
   Google Scholar
• Henquin, personal communication, 1989
   Google Scholar