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Research Article

Neutrophil Gelatinase B and Chemokines in Leukocytosis and Stem Cell Mobilization

S. Starckx Laboratory of Molecular Immunology, Rega Institute, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium
,
P.E. Van den Steen Laboratory of Molecular Immunology, Rega Institute, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium
,
A. Wuyts Laboratory of Molecular Immunology, Rega Institute, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium
,
J. Van Damme Laboratory of Molecular Immunology, Rega Institute, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium
&
G. Opdenakker Laboratory of Molecular Immunology, Rega Institute, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium
Pages 233-241 | Published online: 01 Jul 2009

  • To, L.B., Haylock, D.N., Simmons, P.J. and Juttner, C.A. (1997) "The biology and clinical uses of blood stem cells", Blood 89, 2233-2258.
  • Fu, S. and Liesveld, J. (2000) "Mobilization of hematopoietic stem cells", Blood Reviews 14, 205-218.
  • Champlin, R.E. (1996) "Peripheral blood progenitor cells: a replacement for marrow transplantation?", Seminars in Oncology 23,15-21.
  • Champlin, R.E., Schmitz, N., Horowitz, M.M., Chapuis, B., Chopra, R., Comelissen, J.J., Gale, R.P., Goldman, J.M., Loberiza, F.R., Hertenstein, B., Klein, J.P., Montserrat, E., Zhang, M.J., Ringden, O., Tomany, S.C., Rowlings, P.A., Van Hoef, M.E. and Gratwohl, A. (2000) "Blood stem cells compared with bone marrow as a source of hematopoietic cells for allogeneic transplantation", Blood 95, 3702-3709.
  • Bensinger, W.I., Martin, P.J., Storer, B., Clift, R., Forman, S.J., Negrin, R., Kashyap, A., Flowers, M.E., Lilleby, K., Chauncey, T.R., Storb, R. and Appelbaum, F.R. (2001) "Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers", New England Journal of Medicine 344, 175-181.
  • Opdenakker, G., Fibbe, W.E. and Van Damme, J. (1998) "The molecular basis of leukocytosis", Immunology Today 19, 182-189.
  • Malech, H.L. (1988) "Inflammation: basic principles and clinical correlates", In: Gallin, J.I., Goldstein, I.M. and Snydermann, R., eds, Phagocytic Cells: Egress from Bone Marrow and Diapedesis (Raven Press, New York), Chapter 18, pp 297-308.
  • Prosper, F. and Verfaillie, C.M. (2001) "Regulation of hematopoi-esis through adhesion receptors", Journal of Leukocyte Biology 69, 307-316.
  • Chan, T.Y. and Watt, S.M. (2001) "Adhesion receptors on haematopoietic progenitor cells", British Journal of Haematology 112,541-557.
  • Kraal, G. and Mebius, R.E. (1997) "High endothelial venules: lymphocyte traffic control and controlled traffic", Advances in Immunology 65, 347-395.
  • Pruijt, J.F., van Kooyk, Y., Figdor, C.G., Willemze, R. and Fibbe, W.E. (1999) "Murine hematopoietic progenitor cells with colony-forming or radioprotective capacity lack expression of the ß-integrin LFA-1", Blood 93, 107-112.
  • Springer, T.A. (1994) 'Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm", Cell 76, 301 314.
  • Sullenbarger, B.A., Putitt, M.S., Chong, P., Long, M.W. and Wicha, M.S. (1995) "Murine granulocytic cell adhesion to bone marrow hemonectin is mediated by mannose and galactose", Blood 86. 135-140.
  • Ghaffari, S., Dougherty, G.J., Lansdorp, P.M., Eaves, A.C. and Eaves, C.J. (1995) "Differentiation-associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia", Blood 86, 2976-2985.
  • Verfaillie, C.M., Benis, A., Iida, J., McGlave, P.B. and McCarthy, J.B. (1994) "Adhesion of committed human hematopoietic progenitors to synthetic peptides from the C-terminal heparin-binding domain of fibronectin: cooperation between the integrin a4ß1 and the CD44 adhesion receptor", Blood 84, 1802-1811.
  • Zahalka, M.A., Okon, E., Gosslar, U., Holzmann, B. and Naor, D. (1995) "Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent", Journal of Immu-nology 154, 5345-5355.
  • Papayannopoulou, T. and Nakamoto, B. (1993) "Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin", Proceedings of the National Academy of Science of the USA 90, 9374-9378.
  • Papayannopoulou, T., Priestley, G.V. and Nakamoto, B. (1998) "Anti-VLA4/VCAM-1-induced mobilization requires cooperative signaling through the kit/mkit ligand pathway", Blood 91, 2231-2239.
  • Papayannopoulou, T., Craddock, C., Nakamoto, B., Priestley, G.V. and Wolf, N.S. (1995) "The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen", Proceedings of the National Academy of Science of the USA 92, 9647-9651.
  • Papayannopoulou, T. (2000) "Mechanisms of stem-/progenitor-cell mobilization: the anti-VLA-4 paradigm", Seminars in Hematology 37, 11. 18.
  • Whetton, A.D and Spooncer, E. (1998) "Role of cytokines and extracellular matrix in the regulation of haemopoietic stem cells", Current Opinion in Cell Biology 10, 721-726.
  • Yoder, M.C. and Williams, D.A. (1995) "Matrix molecule interactions with hematopoietic stem cells", Experimental Hema-tology 23, 961-967.
  • Whetton, A.D. and Graham, G.J. (1999) "Homing and mobilization in the stem cell niche", Trends in Cell Biology 9, 233-238.
  • Butcher, E.C. (1991 ) "Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity", Cell 67, 1033-1036.
  • Luster, A.D. (1998) "Chemokines-chemotactic cytokines that mediate inflammation", New England Journal of Medicine 338, 436-445.
  • Peveri, P., Walz, A., Dewald, B. and Baggiolini, M. (1988) "A novel neutrophil-activating factor produced by human mononuclear phagocytes", Journal of Experimental Medicine 167, 1547-1559.
  • Van Damme, J., Van Beeumen, J., Opdenakker, G. and Billiau, A.(1988) "A novel NH2-terminal sequence-characterized human monokine possessing neutrophil chemotactic, skin-reactive, and granulocytosis-promoting activity", Journal of Experimental Medicine 167, 1364-1376.
  • Zlotnik, A. and Yoshie, O. (2000) "Chemokines: a new classification system and their role in immunity", Immunity 12, 121-127.
  • Aiuti, A., Webb, I.J., Bleul, C., Springer, T. and Gutierrez-Ramos, J.C. (1997) "The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood", Journal of Experimental Medicine 185, 111-120.
  • Mohle, R., Bautz, F., Rafii, S., Moore, M.A., Brugger, W. and Kanz, L. (1998)"The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1", Blood 91, 4523-4530.
  • Jo, D.Y., Rafii, S., Hamada, T. and Moore, M.A. (2000) "Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1", Journal of Clinical Investigation 105, 101-111.
  • Broxmeyer, H.E., Kim, C.H., Cooper, S.H., Hangoc, G., Hromas, R. and Pelus, L.M. (1999) "Effects of CC, CXC, C. and CX3C chemokines on proliferation of myeloid progenitor cells, and insights into SDF-1-induced, chemotaxis of progenitors", Annals of the New York Academy of Science 872, 142-162.
  • Craig, J.I., Turner, M.L. and Parker, A.C. (1992) "Peripheral blood stern cell transplantation", Blood Reviews 6, 59-67.
  • Peled, A., Petit, I., Kollet, O., Magid, M., Ponomaryov, T., Byk, T., Nagler, A., Ben-Hur, H., Many, A., Shultz, L., Lider, O., Alon, R., Zipori, D. and Lapidot, T. (1999) "Dependence of human stem cell engraftmenl and repopulation of NOD/SCID mice on CXCR4", Science 283, 845-848.
  • Lataillade, J.J., Clay, D., Dupuy, C., Rigal, S., Jasmin, C., Bourin,P. and Le Bousse-Kerdiles, M.C. (2000) "Chemokine SDF-1 enhances circulating CD34+ cell proliferation in synergy with cytokines: possible role in progenitor survival", Blood 95, 756-768.
  • Link, D.C. (2000) "Mechanisms of granulocyte colony-stimulating factor-induced hematopoietic progenitor-cell mobilization", Semi-nars in Hematohgy 37, 25-32.
  • Peters, W.P., Rosner, G., Ross, M., Vredenburgh, J., Meisenberg, B., Gilbert, C. and Kurtzberg, J (1993) "Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy", Blood 81, 1709-1719.
  • Laterveer, L., Lindley, I.J., Hamilton, M.S., Willemze, R. and Fibbe, W.E. (1995) "lnterleukin-8 induces rapid mobilization of hematopoietic stern cells with radioprotective capacity and long-term myelolymphoid repopulating ability", Blood 85, 2269-2275.
  • Laterveer, I., Lindley, I.J., Heemskerk, D.P., Camps, J.A., Pauwels, E.K., Willemze, R. and Fibbe, W.E. (1996) "Rapid mobilization of hematopoietic progenitor cells in rhesus monkeys by a single intravenous injection of interleukin-8", Blood 87, 781-788.
  • Proost, P., Wuyts, A. and Van Damme, J. (1996) "The role of chemokines in inflammation", International Journal of Clinical and Laboratory Research 26, 211-223.
  • Adams, D.H. and Lloyd, A.R. (1997) "Chemokines: leucocyte recruitment and activation cytokines", Lancet 349, 490-495.
  • Van Damme, J., Van Beeumen, J., Conings, R., Decock, D. and Billiau, A. (1989) "Purification of granulocyte chemotactic peptidc/interleukin-8 reveals N-terminal sequence heterogeneity similar to that of ß-thromboglobulin", European Journal of Biochemistry 181, 337-344.
  • Baggiolini, M., Dewald, B. and Moser, B. (1994) "Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines", Advances in Immunology 55, 97-179.
  • Desbaillets, I., Diserens, A.C., de Tribolet, N., Hamou, M.F. and Van Meir, E.G. (1999) "Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma", Oncogene 18, 1447-1456.
  • Masure, S., Proost, P., Van Damme, J. and Opdenakker, G. (1991) "Purification and identification of 91-kDa neutrophil gelatinase. Release by the activating peptide interleukin-8", European Journal of Biochemistry 198, 391-398.
  • Fibbe, W.E., Pruijt, J.F., Velders, G.A., Opdenakker, G., van Kooyk, Y., Figdor, C.G. and Willemze, R. (1999) "Biology of IL-8-induccd stem cell mobilization", Annals of the New York Academy of Science 872, 71-82.
  • Chuntharapai, A., Lee, J., Hebert, C.A. and Kim, K.J. (1994) "Monoclonal antibodies detect different distribution patterns of IL-8 receptor A and IL-8 receptor B OD human peripheral blood leukocytes", Journal of Immunology 153, 5682-5688.
  • Morohashi, H., Miyawaki, T., Nomura, H., Kuno, K., Murakami, S., Matsushima, K. and Mukaida, N. (1995) "Expression of both types of human interleukin-8 receptors on mature neutrophils, monocytes. and natural killer cells", Journal of Leukocyte Biology 57, 180-187.
  • Lloyd, A.R., Biragyn, A., Johnston, J.A., Taub, D.D., Xu, L., Michiel, D., Sprenger, H., Oppenheim, J.J. and Kelvin, D.J. (1995) "Granulocyte-colony stimulating factor and lipopolysaccharide regulate the expression of interleukin 8 receptors on polymorpho-nuclear leukocytes", Journal of Biological Chemistry 270, 28188-28192.
  • Betsuyaku, T., Liu, F., Senior, R.M., Haug, J.S., Brown, E.J., Jones, S.L., Matsushima, K. and Link, D.C. (1999) "A functional granulocyte colony-stimulating factor receptor is required for normal chemoattractant-induced neutrophil activation", Journal of Clinical Investigation 103, 825-832.
  • Van Zee, K.J., Fischer, F., Hawes, A.S., Hebert, C.A., Terrell, T.G., Baker, J.B., Lowry, S.F. and Moldawer, L.L. (1992) "Effects of intravenous IL-8 administration in nonhuman primates", Journal of Immunology 148, 1746-1752.
  • Terashima, T., English, D., Hogg, J.C. and van Eeden, S.F. (1998) "Release of polymorphonuclear leukocytes from the bone marrow by interleukin-8", Blood 92, 1062-1069.
  • van Eeden, S.F. and Terashima, T. (2000) "Interleukin 8 (IL-8) and the release of leukocytes from the bone marrow", Leukemia and Lymphoma 37, 259-271
  • Cacalano, G., Lee, J., Kikly, K., Kyan, A.M., Pitts-Meek, S., Hultgren, B., Wood, W.I. and Moore, M.W. (1994) "Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog", Science 265, 682 684.
  • Moore, M.W., Cacalano, G., Wood, W.I. and Bailish, E. (1995) 'Neutrophilia in mice that lack the murine IL-8 receptor homolog", Science 269, 1590-1591.
  • Laterveer, L., Zijlmans, J.M., Lindley, I.J., Hamilton, M.S., Willemze, R. and Fibbe, W.E. (1996) "Improved survival of lethally irradiated recipient mice transplanted with circulating progenitor cells mobilized by IL-8 after pretreatment with stem cell factor", Experimental Hematology 24, 1387-1393
  • Watanabe, T., Kawano, Y., Kanamaru, S., Onishi, T., Kaneko, S., Wakata, Y., Nakagawa, R., Makimoto, A., Kuroda, Y., Takaue, Y. and Talmadge, J.E. (1999) "Endogenous interlcukin-8 (IL-8) surge in granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization", Blood 93, 1157-1163.
  • Pruijt, J.F., van Kooyk, Y., Figdor, C.G., Lindley, I.J., Willemze, R. and Fibbe, W.E. (1998) "Anti-LFA-1 blocking antibodies prevent mobilization of hematopoietic progenitor cells induced by interleukin-8", Blood 91, 4099-4105.
  • Wang, J., Zhang, Y. Kasahara, T., Harada, A., Matsushima, K. and Mukaida, N. (1996) "Detection of mouse IL-8 receptor homologue expression on peripheral blood leukocytes and mature myeloid lineage cells in bone marrow", Journal of Leukocyte Biology 60, 372-381.
  • Sopata, I. and Dancewicz, A.M. (1974) "Presence of a gelatinspecific proteinase and its latent form in human leucocytes", Biochimica et Biophysica Acta 370, 510-523.
  • Rudd, P.M., Mattu, T.S., Masure, S., Bratt, T., Van den Steen, P.E., Wormald, M.R., Kuster, B., Harvey, D.J., Borrcgaard, N., Van Damme, J., Dwek, R.A. and Opdenakker, G. (1999) "Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin", Biochemistry 38, 13937-13950.
  • Opdenakker, G., Masure, S., Proost, P., Billiau, A. and Van Damme, J. (1991) "Natural human monocyte gelatinase and its inhibitor", FEBS Letters 284, 73-78.
  • Wilhelm, S.M., Collier, I.E., Marmer, B.L., Eisen, A.Z. Grant, G.A. and Goldberg, G.I. (1989) "SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages", Journal of Biological Chemistry 264, 17213 17221.
  • Masure, S., Billiau, A., Van Damme, J. and Opdenakker, G. (1990) "Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate", Biochimica et Biophysica Acta 1054,317-325.
  • Borregaard, N., Sehesled, M., Nielsen, B.S., Scngelov, H. and Kjeldsen, L. (1995) "Biosynthesis of granule proteins in normal human bone marrow cells. Gelatinase is a marker of terminal neutrophil differentiation", Blood 85, 812-817.
  • Opdenakker, G., Van den Steen, P.P., Dubois, B., Nelissen, I., Van Coillie, F., Masure, S., Proost, P. and Van Damme, J. (2001), "Gelatinase B functions as regulator and effector in leukocyte biology", Journal of Leukocyte Biology, 69, 851-859.
  • Kjeldsen, L., Johnsen, A.H., Sengelov, H. and Borregaard, N. (1993) "Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase", Journal of Biological Chemistry 268, 10425-10432.
  • Opdenakker, G., Masure, S., Grillel, B. and Van Damme, J. (1991) "Cytokine-mediated regulation of human leukocyte gelatinases and role in arthritis", Lymphokine and Cytokine Research 10, 317-324.
  • Masure, S., Paemen, L., Van Aelst, I., Fiten, P., Proost, P., Billiau, A., Van Damme, J. and Opdenakker, G. (1997) "Production and characterization of recombinant active mouse gelatinase B from eukaryotic cells and in vivo effects after intravenous administration", European Journal of Biochemistry 244, 21-30.
  • Pruijt, J.F., Fibbe, W.E., Laterveer, L., Pieters, R.A., Lindley, I.J., Paemen, L., Masure, S., Willemze, R. and Opdenakker, G. (1999) "Prevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against the metalloproteinase gelatinase B (MMP-9)", Proceedings of the National Academy of Science of the USA 96, 10863-10868.
  • Paemen, L., Martens, E., Masure, S. and Opdenakker, G. (1995) "Monoclonal antibodies specific for natural human neutrophil gelatinase B used for affinity purification, quantitation by two-site ELISA and inhibition of enzymatic activity", European Journal of Biochemistry 234, 759-765.
  • Janowska-Wieczorek, A., Marquez, L.A., Matsuzaki, A., Hashmi, H.R., Larratt, L.M., Boshkov, L.M., Turner, AR., Zhang, M.C., Edwards, D.R. and Kossakowska, A.E. (1999) "Expression of matrix metalloproteinases (MMP-2 and -9) and tissue inhibitors of metalloproteinases (TIMP-1 and -2) in acute myelogenous leukaemia blasts: comparison with normal bone marrow cells", British Journal of Haematology 105, 402 411.
  • Fibbe, W.E., Pruijt, J.F., van Kooyk, Y., Figdor, C. G., Opdenakker, G., and Willemze, R. (2000) "The role of metalloproteinases and adhesion molecules in interleukin-8-induced stem-cell mobilization", Seminars in Hematology 37, 19-24.
  • Liu, F., Poursine-Laurent, J. and Link, D.C. (1997) "The granulocyte colony-stimulating factor receptor is required for the mobilization of murine hematopoietic progenitors into peripheral blood by cyclophosphamide or interleukin-8 but not flt-3 ligand", Blood 90, 2522-2528.
  • Betsuyaku, T., Shipley, J.M., Liu, Z. and Senior, R.M. (1999) "Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B", American Journal of Respiratory Cell and Molecular Biology 20, 1303 1309.
  • Liu, Z., Shipley, J.M., Vu, T.H., Zhou, X., Diaz, L.A., Werb, Z. and Senior, R.M. (1998) "Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid", Journal of Experimental Medicine 188, 475-482.
  • D'Haese, A., Wuyts, A., Dillen, C., Dubois, B., Billiau, A., Heremans, H., Van Damme, J., Arnold, B. and Opdenakker, G. (2000) "In vivo neutrophil recruitment by granulocyte chemotactic protein-2 is assisted by gelatinase B/MMP-9 in the mouse", Journal of Interferon and Cytokine Research 20, 667-674.
  • Van den Steen, P.E., Proost, P., Wuyts, A., Van Damme, J. and Opdenakker, G. (2000) "Neutrophil gelatinasc B potentiates interleukin-8 tenfold by aminoteminal processing, whereas it degrades CTAP-III, PF-4, and GRO-a and leaves RANTES and MCP-2 intact", Blood 96, 2673-2681.
  • Haelens, A., Wuyts, A., Proost, P., Struyf, S., Opdenakker, G. and Van Damme, J. (1996) "Leukocyte migration and activation by murine chemokines", Immunobiology 195, 499-521.
  • Lee, J., Cacalano, G., Camerato, T., Toy, K., Moore, M.W. and Wood, W.I. (1995) "Chemokine binding and activities mediated by the mouse IL-8 receptor", Journal of Immunology 155, 2158-2164.
  • Wuyts, A., Haelcns, A., Proost, P., Lenaerts, J.P., Conings, R., Opdenakker, G. and Van Damme, J. (1996) "Identification of mouse granulocyte chemotaclic protein-2 from fibroblasts and epithelial cells. Functional comparison with natural KC and macrophage inflammatory protein-2", Journal of Immunology 157, 1736-1743.
  • Wuyts, A., D'Haese, A., Cremers, V., Menten, P., Lenaerts, J.P., De Loof, A., Heremans, H., Proost, P. and Van Damme, J. (1999) "NH2- and COOH-terminal truncations of murine granulocyte chemotactic protein-2 augment the in vitro and in vivo neutrophil chemotactic potency", Journal of Immunology 163, 6155-6163.
  • Baldwin, E.T., Weber, I.T., St Charles, R., Xuan, J.C., Apella, E., Yamanda, M., Matsushima, K., Edwards, B.F., Clore, G.M. and Gronenbom, A.M. (1991) "Crystal structure of interleukin-8: symbiosis of NMR and crystallography", Proceeding of the National Academy of Science of the USA 88, 502-506.

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