112
Views
19
CrossRef citations to date
0
Altmetric
Original

Prolonged QT Interval Is Associated with Blood Pressure Rather Than Left Ventricular Mass in Spontaneously Hypertensive Rats

, , &
Pages 475-485 | Published online: 03 Jul 2009

References

  • Chapman N, Mayet J, Ozkor M, Lampe FC, Thom SA, Poulter NR. QT intervals and QT dispersion as measures of left ventricular hypertrophy in an unselected hypertensive population. Am J Hypertens. 2001; 14: 455–462
  • Oikarinen L, Nieminen MS, Viitasalo M, Toivonen L, Jern S, Dahlof B, Devereux RB, Okin PM, LIFE Study Investigators. QRS duration and QT interval predict mortality in hypertensive patients with left ventricular hypertrophy: The Losartan Intervention for Endpoint Reduction in Hypertension Study. Hypertension 2004; 43: 1029–1034
  • Straus SM, Kors JA, De Bruin ML, van der Hooft CS, Hofman A, Heeringa J, Deckers JW, Kingma JH, Sturkenboom MC, Stricker BH, Witteman JC. Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol. 2006; 47: 362–367
  • Oikarinen L, Nieminen MS, Toivonen L, Viitasalo M, Wachtell K, Papademetriou V, Jern S, Dahlof B, Devereux RB, Okin PM, LIFE Study Investigators. Relation of QT interval and QT dispersion to regression of echocardiographic and electrocardiographic left ventricular hypertrophy in hypertensive patients: The Losartan Intervention For Endpoint Reduction (LIFE) study. Am Heart J. 2003; 145: 919–925
  • Baillard C, Mansier P, Ennezat PV, Mangin L, Medigue C, Swynghedauw B, Chevalier B. Converting enzyme inhibition normalizes QT interval in spontaneously hypertensive rats. Hypertension. 2000; 36: 350–354
  • Matsumura K, Takata Y, Ansai T, Awano S, Takehara T, Fujii K, Iida M. Association of QT interval with blood pressure in 80-year-old subjects. Hypertens Res. 2004; 27: 387–391
  • Peng S, Yu Y, Hao K, Xing H, Li D, Chen C, Huang A, Hong X, Feng Y, Zhang Y, Li J, Wang B, Wu D, Wang X, Xu X. Heart rate-corrected QT interval duration is significantly associated with blood pressure in Chinese hypertensives. J Electrocardiol. 2006; 39: 206–210
  • Passino C, Franzoni F, Gabutti A, Poletti R, Galetta F, Emdin M. Abnormal ventricular repolarization in hypertensive patients: Role of sympatho-vagal imbalance and left ventricular hypertrophy. Int J Cardiol. 2004; 97: 57–62
  • Marfella R, Gualdiero P, Siniscalchi M, Carusone C, Verza M, Marzano S, Esposito K, Giugliano D. Morning blood pressure peak, QT intervals, and sympathetic activity in hypertensive patients. Hypertension. 2003; 41: 237–243
  • Hammond IW, Devereux RB, Alderman MH, Laragh JH. Relation of blood pressure and body build to left ventricular mass in normotensive and hypertensive employed adults. J Am Coll Cardiol. 1988; 12: 996–1004
  • Kannel WB. Left ventricular hypertrophy as a risk factor: The Framingham experience. J Hypertens 1991; 9: S3–S9
  • Trippodo NC, Frohlich ED. Similarities of genetic (spontaneous) hypertension. Man and rat. Circ Res. 1981; 48: 309–319
  • Ruskoaho H, Leppaluoto J. Immunoreactive atrial natriuretic peptide in ventricles, atria, hypothalamus, and plasma of genetically hypertensive rats. Circ Res. 1988; 62: 384–394
  • Shorofsky SR, Aggarwal R, Corretti M, Baffa JM, Strum JM, Al-Seikhan BA, Kobayashi YM, Jones LR, Wier WG, Balke CW. Cellular mechanisms of altered contractility in the hypertrophied heart. Big hearts, big sparks. Circ Res. 1999; 84: 424–434
  • Aiello EA, Villa-Abrille MC, Escudero EM, Portiansky EL, Perez NG, de Hurtado MC, Cingolani HE. Myocardial hypertrophy of normotensive Wistar-Kyoto rats. Am J Physiol Heart Circ Physiol 2004; 286: H1229–H1235
  • Bell D, Kelso EJ, Argent CC, Lee GR, Allen AR, McDermott BJ. Temporal characteristics of cardiomyocyte hypertrophy in the spontaneously hypertensive rat. Cardiovasc Pathol. 2004; 13: 71–78
  • Lu HR, Yu F, Dai DZ, Remeysen P, De Clerck F. Reduction in QT dispersion and ventricular arrhythmias by ischaemic preconditioning in anaesthetized, normotensive and spontaneously hypertensive rats. Fundam Clin Pharmacol. 1999; 13: 445–454
  • Yamori Y, Ohtaka M, Nara Y. Vectorcardiographic study on left ventricular hypertrophy in spontaneously hypertensive rats. Jpn Circ J. 1976; 40: 1315–1329
  • Cerbai E, Barbieri M, Li Q, Mugelli A. Ionic basis of action potential prolongation of hypertrophied cardiac myocytes isolated from hypertensive rats of different ages. Cardiovasc Res. 1994; 28: 1180–1187
  • Dean JW, Lab MJ. Effect of changes in load on monophasic action potential and segment length of pig heart in situ. Cardiovasc Res. 1989; 23: 887–896
  • Hansen DE. Mechanoelectrical feedback effects of altering preload, afterload, and ventricular shortening. Am J Physiol 1993; 264: H423–H432
  • Yee KM, Lim PO, Ogston SA, Struthers AD. Effect of phenylephrine with and without atropine on QT dispersion in healthy normotensive men. Am J Cardiol. 2000; 85: 69–74
  • Diedrich A, Jordan J, Shannon JR, Robertson D, Biaggioni I. Modulation of QT interval during autonomic nervous system blockade in humans. Circulation. 2002; 106: 2238–2243
  • Buschmann G, Schumacher W, Budden R, Kuhl UG. Evaluation of the effect of dopamine and other catecholamines on the electrocardiogram and blood pressure of rats by means of on-line biosignal processing. J Cardiovasc Pharmacol. 1980; 2: 777–795
  • McDougall SJ, Paull JR, Widdop RE, Lawrence AJ. Restraint stress: Differential cardiovascular responses in Wistar-Kyoto and spontaneously hypertensive rats. Hypertension 2000; 35: 126–129
  • Tsunoda M, Takezawa K, Santa T, Ina Y, Nagashima K, Ohmori K, Kobayashi S, Imai K. New approach for measurement of sympathetic nervous abnormality in conscious, spontaneously hypertensive rats. Jpn J Pharmacol. 2000; 83: 39–45
  • Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde AM. Genetic and molecular basis of cardiac arrhythmias: Impact on clinical management, parts I and II. Circulation. 1999; 99: 518–528
  • Bacharova L, Kyselovic J, Klimas J. The initial stage of left ventricular hypertrophy in spontaneously hypertensive rats is manifested by a decrease in the QRS amplitude/left ventricular mass ratio. Clin Exp Hypertens. 2004; 26: 557–567
  • Devereux RB. Does increased blood pressure cause left ventricular hypertrophy or vice versa?. Ann Intern Med. 1990; 112: 157–159
  • Harrap SB, Dominiczak AF, Fraser R, Lever AF, Morton JJ, Foy CJ, Watt GC. Plasma angiotensin II, predisposition to hypertension, and left ventricular size in healthy young adults. Circulation. 1996; 93: 1148–1154
  • Drayer JI, Gardin JM, Brewer DD, Weber MA. Disparate relationships between blood pressure and left ventricular mass in patients with and without left ventricular hypertrophy. Hypertension 1987; 9: II61–II64
  • Mayet J, Shahi M, McGrath K, Poulter NR, Sever PS, Foale RA, Thom SA. Left ventricular hypertrophy and QT dispersion in hypertension. Hypertension. 1996; 28: 791–796
  • Zoghi M, Gurgun C, Yavuzgil O, Akilli A, Turkoglu C, Kultursay H, Akin M. QT dispersion in patients with different etiologies of left ventricular hypertrophy: The significance of QT dispersion in endurance athletes. Int J Cardiol. 2002; 84: 153–159
  • Abildskov JA. Adrenergic effects of the QT interval of the electrocardiogram. Am Heart J. 1976; 92: 210–216

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.