- Cockfort, D.L. (1990) Dissection and Culture of Postimplantation Embryos (Oxford University Press, New York).
- Ishibashi, M., Akazawa, S., Sakamaki, H., Matsumoto, K., Yamasaki, H., Yamaguchi, Y, Goto, S., Urata, Y, Kondo, T. and Nagataki, S. (1997) "Oxygen induced embryopathy and the significance of glutathione-dependent antioxidant system in the rat embryo during early organogenesis", Free Radic. Biol. Med. 22, 447-454.
- New, D.A. and Coppola, P.T. (1970) "Development of explanted rat fetuses in hyperbaric oxygen", Teratology 3, 153-161.
- Ferm, V.H. (1964) "Teratogenic effects of hyperbaric oxygen", Proc. Soc. Exp. Biol. Med. 116, 975-976.
- Miller, P.D., Telford, I.R. and Haas, G.R. (1971) "Effect of hyperbaric oxygen on cardiogenesis in the rat", Biol. Neonate 17, 44-52.
- Telford, I.R., Miller, P.D. and Haas, G.F. (1969) "Hyperbaric oxygen causes fertal wastage in rats", Lancet 2, 220-221.
- Sapunar, D., Saraga-Babic, M, Peruzovic, M. and Marusic, M. (1993) "Effects of hyperbaric oxygen on rat embryos", Biol. Neonate 63, 360-369.
- New, D.A. and Coppola, P.T. (1970) "Effects of different oxygen concentrations on the development of rat embryos in culture", J. Reprod. Fertil. 21, 109-118.
- Morriss, G. and New, D.T. (1979) "Effect of oxygen concentration on morphogenesis of cranial neural folds and neural crest in cultured rat embryos", J. Embryol. Exp. Morphol. 54, 17-35.
- Chen, E.Y., Fujinaga, M. and Giaccia, A.J. (1999) "Hypoxic microenvironment within an embryo induces apoptosis and is essential for proper morphological development", Teratology 60, 215-225.
- Eklund, H., Cambillau, C., Sjoberg, B.M., Holmgren, A., Jornvall, H., Hoog, J.O. and Branden, C.I. (1984) "Conformational and functional similarities between glutaredoxin and thioredoxins", EMBO J. 3, 1443-1449.
- Holmgren, A. (1985) "Thioredoxin", Annu. Rev. Biochem. 54, 237-271.
- Holmgren, A. (1989) "Thioredoxin and glutaredoxin systems", J. Biol. Chem. 264, 13963-13966.
- Nakamura, H., Matsuda, M., Furuke, K., Kitaoka, Y, Iwata, S., Toda, K., Inamoto, T., Yamaoka, Y, Ozawa, K. and Yodoi, J. (1994) "Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide", Immunol. Lett. 42, 75-80.
- Nakamura, H., Nakamura, K. and Yodoi, J. (1997) "Redox regulation of cellular activation", Annu. Rev. Immunol. 15, 351-369.
- Hirota, K., Matsui, M., Iwata, S., Nishiyama, A., Mori, K. and Yodoi, J. (1997) "AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1", Proc. Natl Acad. Sci. USA 94, 3633-3638.
- Okamoto, T., Ogiwara, H., Hayashi, T., Mitsui, A., Kawabe, T. and Yodoi, J. (1992) "Human thioredoxin/adult T cell leukemia-derived factor activates the enhancer binding protein of human immunodeficiency virus type 1 by thiol redox control mechanism", Int. Immunol. 4, 811-819.
- Ueno, M., Masutani, H., Arai, R.J., Yamauchi, A., Hirota, K., Sakai, T., Inamoto, T., Yamaoka, Y, Yodoi, J. and Nikaido, T. (1999) "Thioredoxin-dependent redox regulation of p53-mediated p21 activation", J. Biol. Chem. 274, 35809-35815.
- Nordberg, J. and Arner, E. (2001) "Reactive oxygen species, antioxidants, and the mammalian thioredoxin system", Free Radic. Biol. Med. 31, 1287-1312.
- Meyer, M., Schreck, R. and Baeuerle, P.A. (1993) "H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidantresponsive factor", EMBO J. 12, 2005-2015.
- Kobayashi, M., Nakamura, H., Yodoi, J. and Shiota, K. (2000) "Immunohistochemical localization of thioredoxin and glutaredoxin in mouse embryos and fetuses", Antioxid. Redox Signal. 2, 653-663.
- Takagi, Y, Mitsui, A., Nishiyama, A., Nozaki, K., Sono, H., Gon, Y, Hashimoto, N. and Yodoi, J. (1999) "Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage", Proc. Natl Acad. Sci. USA 96, 4131-4136.
- Klug, S., Lewandowski, C., Blankenburg, G., Merker, H.J. and Neubert, D. (1985) "Effect of acyclovir on mammalian embryonic development in culture", Arch. Toxicol. 58, 89-96.
- Takagi, Y, Horikawa, F, Nozaki, K., Sugino, T., Hashimoto, N. and Yodoi, J. (1998) "Expression and distribution of redox regulatory protein, thioredoxin during transient focal brain ischemia in the rat", Neurosci. Lett. 251, 25-28.
- Tomimoto, H., Akiguchi, I., Wakita, H., Kimura, J., Hori, K. and Yodoi, J. (1993) "Astroglial expression of ATL-derived factor, a human thioredoxin homologue, in the gerbil brain after transient global ischemia", Brain Res. 625, 1-8.
- Nakamura, H., Bai, J., Nishinaka, Y, Ueda, S., Sasada, T., Ohshio, G., Imamura, M., Takabayashi, A., Yamaoka, Y. and Yodoi, J. (2000) "Expression of thioredoxin and glutaredoxin, redox-regulating proteins, in pancreatic cancer", Cancer Detect. Prev. 24, 53-60.
- Toyokuni, S., Tanaka, T., Hattori, Y, Nishiyama, Y, Yoshida, A., Uchida, K., Hiai, H., Ochi, H. and Osawa, T. (1997) "Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model", Lab. Investig. 76, 365-374.
- Fantel, A.G. (1996) "Reactive oxygen species in developmental toxicity: review and hypothesis", Teratology 53, 196-217.
- Schardein, J.L. (2000) Chemically Induced Birth Defects (Marcel Dekker, New York).
- Shepard, T.H. (1998) Catalog of Teratogenic Agents (Johns Hopkins University Press, Baltimore).
- Winn, L.M. and Wells, P.G. (1999) "Maternal administration of Superoxide dismutase and catalase in phenytoin teratogenicity", Free Radic. Biol. Med. 26, 266-274.
- Eriksson, U.J., Borg, L.A., Forsberg, H. and Styrud, J. (1991) "Diabetic embryopathy. Studies with animal and in vitro models", Diabetes 40(Suppl. 2), 94-98.
- Eriksson, U.J. and Borg, L.A. (1991) "Protection by free oxygen radical scavenging enzymes against glucose-induced embryonic malformations in vitro", Diabetologia 34, 325-331.
- Trocino, R.A., Akazawa, S., Ishibashi, M., Matsumoto, K., Matsuo, H., Yamamoto, H., Goto, S., Urata, Y, Kondo, T. and Nagataki, S. (1995) "Significance of glutathione depletion and oxidative stress in early embryogenesis in glucose-induced rat embryo culture", Diabetes 44, 992-998.
- Wentzel, P., Thunberg, L. and Eriksson, U.J. (1997) "Teratogenic effect of diabetic serum is prevented by supplementation of Superoxide dismutase and N-acetylcysteine in rat embryo culture", Diabetologia 40, 7-14.
- Matsui, M., Oshima, M., Oshima, H., Takaku, K., Maruyama, T., Yodoi, J. and Taketo, M.M. (1996) "Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene", Dev. Biol. 178, 179-185.
- Das, K.C. and Das, C.K. (2000) "Thioredoxin, a singlet oxygen quencher and hydroxyl radical scavenger: Redox independent functions", Biochem. Biophys. Res. Commun. 277, 443-447.
- Mitsui, A., Hirakawa, T. and Yodoi, J. (1992) "Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemia-derived factor/human thioredoxin", Biochem. Biophys. Res. Commun. 186, 1220-1226.
- Chae, H.Z., Robison, K., Poole, L.B., Church, G. and Storz, G. (1994) "Cloning and sequencing of thiol-specific antioxidant from mammalian brain: Alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes", Proc. Natl Acad. Sci. USA 91, 7017-7021.
- Netto, L., Chae, H.Z., Kang, S.W., Rhee, S.G. and Stadtman, E.R. (1996) "Removal of hydrogen peroxide by thiol-specific antioxidant enzyme (TSA) is involved with its antioxidant properties", J. Biol. Chem. 271, 15315-15321.
- Lewin, M.H., Hume, R., Howie, A.F., Richard, K., Arthur, J.R., Nicol, E, Walker, S.W. and Beckett, G.J. (2001) "Thioredoxin reductase and cytoplasmic glutathione peroxidase activity in human foetal and neonatal liver", Biochem. Biophys. Acta 1526, 237-241.
- Das, K.C., Guo, X. and White, C.W. (1999) "Induction of thioredoxin reductase gene expression in lings of newborn primates by oxygen", Am. Physiol. Soc. 276, L530-L539.
- Rozell, B., Hansson, H.A., Luthman, M. and Holmgren, A. (1985) "Immunohistochemical localization of thioredoxin and thioredoxin reductase in adult rats", Eur. J. Cell Biol. 38, 79-86.
- Reaume, A.G., Elliott, J.L., Hoffman, E.K., Kowall, N.W., Ferrante, R.J., Siwek, D.E., Wilcox, H.M., Flood, D.L., Seal, M.F., Brown, R.H.J., Scott, R.W. and Sinder, W.D. (1996) "Motor neurons in Cu/Zn Superoxide dismutasedeficient mice develop normally but exhibit enhanced cell death after axonal injury", Nat. Genet. 13, 43-47.
- Li, Y, Huang, T.T., Calson, E.J., Melov, S., Ursell, P.C., Olson, J.L., Noble, L.J., Yoshimura, M.P, Berger, C., Chan, PH., Wallace, D.C. and Epstein, C.J. (1995) "Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese Superoxide dismutase", Nat. Genet. 11, 376-381.
- Carlsson, L.M., Jonsson, J., Edlund, T. and Marklund, S.L. (1995) "Mice lacking extracellular Superoxide dismutase are more sensitive to hyperoxia", Proc. Natl Acad. Sci. USA 92, 6264-6268.
- Ho, Y.S., Magnenat, J.L., Bronson, R.T., Cao, J., Gargano, M., Sugawara, M. and Funk, C.D. (1997) "Mice deficient in cellular glutathione peroxides develop normally and show no increased sensitivity to hyperoxia", J. Biol. Chem. 272, 16644-16651.
- de Haan, J.B., Bladier, C., Griggiths, P., Keiner, M., O'Shea, R.D., Cheung, N.S., Bronson, R.T., Silvestro, M.J., Wild, S., Zheng, S.S., Beart, P.M., Hertzog, P.J. and Kola, I. (1998) "Mice with a homozygous null mutation for the most abundant gluthathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide", J. Biol. Chem. 273, 22528-22536.
- Saitoh, M., Nishitoh, H., Fujii, M., Takeda, K., Tobiume, K., Sawada, Y, Kawabata, M., Miyazono, K. and Ichijo, H. (1998) "Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1", EMBO J. 17, 2596-2606.
- Ichijo, H. (1997) "Induction of apoptosis by ASKl, a mammalian MAPKKK that activates SAPK/JNK abd p38 signaling pathways", Science 275, 90-94.
Thioredoxin, an Anti-oxidant Protein, Protects Mouse Embryos from Oxidative Stress-induced Developmental Anomalies
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.