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Research Article

Acute Phase Immune Response to Exercise Coexists with Decreased Neutrophil Antioxidant Enzyme Defences

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Pages 1101-1107 | Published online: 07 Jul 2009

  • Hessel, E., Haberland, A., Müller, M., Lerche, D. and Schimke, I. (2000) "Oxygen radical generation of neutrophils: a reason for oxidative stress during marathon running?", Clin. Chim. Acta 298, 145-156.
  • Ji, Ll. (1999) "Antioxidants and oxidative stress in exercise", Proc. Sac. Exp. Biol. Med. 222, 283-292.
  • Cannon, J. and Blumberg, J.B. (2000) "Acute phase immune responses in exercise", In: Sen, C.K., Packer, L. and Hänninen, O., eds, Handbook of Oxidants and Antioxidants in Exercise (Elsevier Science B.V., Amsterdam), pp 177-194.
  • Shek, P.N. and Shephard, R.J. (1998) "Physical exercise as a human model of limited inflammatory response", Can. J. Physiol. Pharmacol. 76, 589-597.
  • Tidball, J.G. (1995) "Inflammatory cell response to acute muscle injury", Med. Sci. Sports Exerc. 27, 1022-1032.
  • Pizza, EX., Davis, B.H., Henrickson, S.D., Mitchell, J.B., Pace, J.F., Bigelow, N., Di Lauro, P. and Naglieri, T. (1996) "Adaptation to eccentric exercise: effect on CD64 and CDllb/CD18 expression", J. Appl. Physiol. 80, 47-55.
  • Petersen, E.W., Ostrowski, K., Ibfelt, T., Richelle, M., Offord, E., Halkjaer-Kristensen, J. and Pedersen, B.K. (2001) "Effect of vitamin supplementation on cytokine response and on muscle damage after strenuous exercise", Am. J. Physiol. Cell Physiol. 280, C1570-C1575.
  • Ostrowski, K., Schjerling, P. and Pedersen, B.K. (2001) "Physical activity and plasma interleukin-6 in humans-effect of intensity of exercise", Eur. J. Appl. Physiol. 83, 512-515.
  • Nieman, D.C. (1994) "Exercise, upper respiratory tract infection, and the immune system", Med. Sci. Sports Exerc. 26, 128-139.
  • Suzuki, K., Totsuka, M., Nakaji, S., Yamada, M., Kudoh, S., Liu, Q., Sugawara, K., Yamaya, K. and Sato, K. (1999)"Endurance exercise causes interaction among stress hormones, cytokines, neutrophil dynamics and muscle damage", J. Appl. Physiol. 87, 1360-1367.
  • Verhoef, J. and Visser, M.R. (1993) "Neutrophil phagocytosis and killing: normal function and microbial evasion", In: Abramson, J.S. and Wheeler, J.G., eds, The Neutrophil (Oxford University Press, New York), pp 109-137.
  • Cannon, J. and Blumberg, J.B. (1994) "Acute phase immune responses in exercise", In: Sen, C.K., Packer, L. and Hänninen, O., eds, Exercise and Oxygen Toxicity (Elsevier Science B.V., Amsterdam), pp 447-462.
  • El Hag, A. and Clark, R.A. (1987) "Immunosuppression by activated human neutrophils. Dependence on the myeloperoxidase system", J. Immunol. 139, 2406-2413.
  • Clarkson, P.M. and Thompson, H.S. (2000) "Antioxidants: what role do they play in physical activity and health?", Am. J. Clin. Nutr. 72, 637S-646S.
  • Washko, P.W., Wang, Y. and Levine, M. (1993) "Ascorbic acid recycling in human neutrophils", J. Biol. Chem. 268, 15531-15535.
  • Welch, R.W, Wang, Y, Crossman, A., Park, J.B., Kirk, K.L. and Levine, M. (1995) "Accumulation of vitamin C (ascorbate) and its oxidized metabolite dehydroascorbic acid occurs by separate mechanisms", J. Biol. Chem. 270, 12584-12592.
  • Malm, C., Lenkei, R. and Sjodin, B. (1999) "Effects of eccentric exercise on the immune system in men", J. Appl. Physiol. 86, 461-468.
  • Sen, C.K., Atalay, M. and Hanninen, O. (1994) "Exercise-induced oxidative stress: glutathione supplementation and deficiency", J. Appl. Physiol. 77, 2177-2187.
  • Sen, C.K. and Packer, L. (2000) "Thiol homeostasis and supplements in physical exercise", Am. J. Clin. Nutr. 72, 635S-669S.
  • Laaksonen, D.E., Atalay, M., Niskanen, L., Uusitupa, M., Hanninen, O. and Sen, C.K. (1999) "Blood glutathione homeostasis as a determinant of resting and exercise-induced oxidative stress in young men", Redox Rep. 4, 53-59.
  • Gohil, K., Viguie, C., Stanley, W.C., Brooks, G.A. and Packer, L. (1988) "Blood glutathione oxidation during human exercise", J. Appl. Physiol. 64, 115-119.
  • Vifta, J., Sastre, J., Asensi, M. and Packer, L. (1995) "Assay of blood glutathione oxidation during physical exercise", In: Packer, L., ed, Methods in Enzymology (Academic, New York) 251, pp 237-243.
  • Lew, H., Pyke, S. and Quintanilha, A. (1985) "Changes in glutathione status of plasma, liver and muscle following exhaustive exercise in rats", FEBS Lett. 185, 262-266.
  • Tauler, P., Aguilo, A., Gimeno, I., Guix, M.P. and Pons, A. (1999) "Regulation of erythrocyte antioxidant enzyme activities in athletes during competition and short-term recovery", Eur. J. Physiol. 438, 782-787.
  • Boyum, A. (1964) "Separation of white blood cells", Nature 204, 793-794.
  • Aebi, H.E. (1984) "Catalase", In: Bergmeyer, H.U., ed, Methods in Enzymatic Analysis (Verlag Chemie, Basel), pp 273-286.
  • Goldberg, D.M. and Spooner, R.J. (1985) "Glutathione reductase", In: Bergmeyer, H.U., ed, Methods in Enzymatic Analysis (Verlag Chemie, Basel), pp 258-265.
  • Flohe, L. and Gunzler, WA. (1984) "Assays for glutathione peroxidase", Methods Enzymol. 105, 114-121.
  • McCord, J. and Fridovich, I. (1969) "Superoxide dismutase an enzymic for erythrocuprein (haemocuprein)", J. Biol. Chem. 244, 6049.
  • Puigserver, P., Lladó, I., Palou, A. and Gianotti, M. (1991) "Evidence for masking of brown adipose tissue mitochondrial GDP-binding sites in response to fasting in rats made obese by dietary manipulation. Effects of reversion to standard diet", Biochem. J. 279, 575-579.
  • Dhariwal, K.R., Washko, P.W. and Levine, M. (1990) "Determination of dehydroascorbic acid using high performance liquid chromatography with coulometric electrochemical detection", Anal. Biochem. 189, 18-23.
  • Tsao, C.S. and Salimi, S.L. (1982) "Differential determination of L-ascorbic acid and D-isoascorbic acid by reversed-phase high performance liquid chromatography with electrochemical detection", J. Chromatogr. 245, 355-358.
  • Winters, R.A., Zukowski, J., Ercal, N., Matthews, R.H. and Spitz, D.R. (1995) "Analysis of glutathione, glutathione disulfide, cysteine, homocysteine, and other biological thiols by high-performance liquid chromatography following derivatization by n-(l-pyrenyl)maleimide", Anal. Biochem. 227, 14-21.
  • Gabriel, H. and Kindermann, W. (1997) "The acute immune response to exercise: what does it mean", Int. J. Sports Med. 18, S28-S45.
  • Pyne, D.B., Baker, M.S., Smith, J.A., Telford, R.D. and Weidemann, M.J. (1996) "Exercise and the neutrophil oxidative burst: biological and experimental variability", Eur. J. Appl. Physiol. 74, 564-571.
  • Sato, H., Abe, T., Kikuchi, K., Endo, T., Hasegawa, H., Suzuki, K., Nakaji, S., Sugawara, K. and Ohta, S. (1996) "Changes in the production of reactive oxygen species from neutrophils following a 100km marathon", Nippon Eiseigaku Zasshi 51, 612-616.
  • Suzuki, K., Naganuma, S., Totsuka, M., Suzuki, K.J., Mochizuki, M., Shiraishi, M., Nakaji, S. and Sugawara, K. (1996) "Effects of exhaustive endurance exercise and its one-week daily repetition on neutrophil count and functional status in untrained men", Int. J. Sports Med. 17, 205-212.
  • Kokot, K., Schaefer, R.M., Teschner, M., Gilge, U., Plass, R. and Heidland, A. (1988) "Activation of leukocytes during prolonged physical exercise", Adv. Exp. Med. Biol. 240, 57-63.
  • Pincemail, J., Camus, G., Roesgen, A., Dreezen, E., Bertrand, Y, Lismonde, M., Deby-Dupont, G. and Deby, C. (1990) "Exercise induces pentane production and neutrophil activation in humans. Effect of propranolol", Eur. J. Appl. Physiol. 61, 319-322.
  • Taylor, C., Rogers, G., Goodman, C., Baynes, R.D., Bothwell, T.H., Bezwoda, W.R., Kramer, F. and Hattingh, J. (1987) "Hematologic, iron-related, and acute-phase protein responses to sustained strenuous exercise", J. Appl. Physiol. 62, 464-469.
  • Cannon, J.G., Orencole, S.F., Fielding, R.A., Meydani, M., Meydani, S.N., Fiatarone, M.A., Blumberg, J.B. and Evans, WJ. (1990) "Acute phase response in exercise: interaction of age and vitamin E on neutrophils and muscle enzyme release", Am. J. Physiol. 259, R1214-R1219.
  • Simon, L.M., Robin, E.D., Phillips, J.R., Acevedo, J., Axline, S.G. and Theore, J. (1977) "Enzymatic basis for bioenergetic differences of alveolar versus peritoneal macrophages and enzyme regulation by molecular QI", J. Clin. Investig. 59, 443-448.
  • Alvarez, S. and Boveris, A. (1993) "Induction of antioxidant enzymes and DT-diaphorase in human blood mononuclear cells by light stress", Arch. Biochem. Biophys. 305, 247-251.
  • Murphy, C. and Newsholme, P. (1998) "Importance of glutamine metabolism in murine macrophages and human monocytes to L-arginine biosynthesis and rates of nitrite or urea production", Clin. Sci. 95, 397-407.
  • Fukai, T., Siegfried, M.R., Ushio-Fukai, M., Cheng, Y, Kojda, G. and Harrison, D.G. (2000) "Regulation of the vascular extracellular Superoxide dismutase by nitric oxide and exercise training", J. Clin. Investig. 105, 1631-1639.
  • Gleeson, M., Robertson, J.D. and Maughan, R.J. (1987) "Influence of exercise on ascorbic acid status in man", Clin. Sci. (Lond) 73, 501-505.
  • Pietarinen-Runtti, P., Lakari, E., Raivio, K.O. and Kinnula, V.L. (2000) "Expression of antioxidant enzymes in human inflammatory cells", Am. J. Physiol. Cell Physiol. 278, C118-C125.
  • Castell, L.M. and Newsholme, E.A. (1998) "Glutamine and the effects of exhaustive exercise upon the immune response", Can. J. Physiol. Pharmacol. 76, 524-532.
  • Aguilo, A., Castano, E., Tauler, P., Guix, M.P., Serra, N. and Pons, A. (2000) "Participation of blood cells in the changes of blood amino acid concentrations during maximal exercise", J. Nutr. Biochem. 11, 81-86.

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