Inhibition of Sudan I genotoxicity in human liver-derived HepG2 cells by the antioxidant hydroxytyrosol

References

• Trichopoulou A, Lagiou P. Healthy traditional Mediterranean diet: an expression of culture, history, and lifestyle. Nutr Rev 1997; 55: 383–389
   PubMed Web of Science ®Google Scholar
• Katan MB, Zock PL, Mensink RP. Dietary oils, serum lipoproteins, and coronary heart disease. Am J Clin Nutr 1995; 61: 1368s–1373s
   PubMed Web of Science ®Google Scholar
• Bravo L. Polyphenols: chemistry, dietary sources, metabolism and nutritional significance. Nutr Rev 1998; 56: 317–333
   PubMed Web of Science ®Google Scholar
• Visioli F, Galli C. The effect of minor constituents of olive oil on cardiovascular disease: new findings. Nutr Rev 1998; 56: 142–147
   PubMed Web of Science ®Google Scholar
• Montedoro GF, Servili M, Baldioli M. Simple and hydrolyzable compounds in virgin olive oil. Spectroscopic characterization of the secoiridoids derivatives. J Agric Food Chem 1993; 41: 2228–2234
   Web of Science ®Google Scholar
• Visioli F, Bellomo G, Galli C. Free radical-scavenging properties of olive oil polyphenols. Biochem Biophys Res Commun 1998; 247: 60–64
   PubMed Web of Science ®Google Scholar
• Papadopoulos G, Boskou D. Antioxidative effect of natural phenols on olive oil. J Am Oil Chem Soc 1991; 68: 669–671
   Web of Science ®Google Scholar
• Baldioli M, Servili M, Perretti G, Montedoro GF. Antioxidant activity of tocopherols and phenolic compounds of virgin olive oil. J Am Oil Chem Soc 1996; 73: 1589–1593
   Web of Science ®Google Scholar
• Stefania DA, Diego I, Valentina M, Alvara S, Giovanna D, Adone B, Lucia M, Maria AT, Marcello Z, Patrizia G. Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells. Free radical Bio Med 2005; 38: 908–919
   PubMed Web of Science ®Google Scholar
• Lambros N, Paschalis TD, Nektarios A, Dimitrios B, Apostolos A, Dimitrios G. DNA protecting and genotoxic effects of olive oil related components in cells exposed to hydrogen peroxide. Free Radic Res 2005; 39: 787–795
   PubMed Web of Science ®Google Scholar
• Manna C, Galletti P, Cucciolla V, Moltedo O, Leone A, Zappia V. The protective effect of the olive oil polyphenol (3,4-dihydroxyphenyl) ethanol counteracts reactive oxygen metabolite-induced cytotoxicity in Caco-2 cells. J Nutr 1997; 127: 286–292
   PubMed Web of Science ®Google Scholar
• Manna C, Galletti P, Cucciolla V, Montedoro G, Zappia V. Olive oil hydroxytyrosol protects human erythrocytes against oxidative damages. J Nutr Biochem 1996; 10: 159–165
   Google Scholar
• Goya L, Mateos R, Bravo L. Effect of the olive oil phenol hydroxytyrosol on human hepatoma HepG2 cells, protection against oxidative stress induced by tert-butylhydroperoxide. Eur J Nutr 2007; 46: 70–78
   PubMed Web of Science ®Google Scholar
• De la Puerta R, Ruiz Gutierrez V, Hoult RS. Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil. Biochem Pharmacol 1999; 57: 445–449
   PubMed Web of Science ®Google Scholar
• Deiana M, Aruoma OI, Bianchi MP, Spencer JPE, Kaur H, Halliwell B, Banni S, Dessi MA, Corongiu FP. Inhibition of peroxynitrite dependent DNA base modification and tyrosine nitration by the extra virgin olive oil-derived antioxidant hydroxytyrosol. Free Radic Biol Med 1999; 26: 762–769
   PubMed Web of Science ®Google Scholar
• Moller P, Wallin H. Genotoxic hazards of azo pigments and other colorants related to 1-phenylazo-2-hydroxynaphthalene. Mutat Res 2000; 462: 13–30
   PubMed Web of Science ®Google Scholar
• Capitan F, Capitan-Vallvey LF, Fernadez MD, Orbe De, Avidad R. Determination of colorant matters in foods by solid-phase spectrophotometry. Anal Chim Acta 1996; 331: 141–148
   Web of Science ®Google Scholar
• Westmoreland C, Gatehouse DG. The differential clastogenicity of Solvent Yellow 14 and FD & C Yellow No. 6 in vivo in the rodent micronucleus test (observation of species and tissues specificity). Carcinogenesis (Lond) 1991; 12: 1403–1407
   PubMed Web of Science ®Google Scholar
• Tsuda S, Matsusaka N, Madarame H, Ueno S, Susa N, Ishida K, Kawamura N, Sekihashi K, Sasaki YF. The comet assay in eight mouse organs: results with 24 azo compounds. Mutat Res 2000; 465: 11–26
   PubMed Web of Science ®Google Scholar
• Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K. Mortelmans, salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals. Environ Mol Mutagen 1998; 12(Suppl.11)1–157
   Google Scholar
• An Y, Liping J, Jun C, ChengYan G, Laifu Zh. Sudan I induces genotoxic effects and oxidative DNA damage in HepG2 cells. Mutat Res 2007; 627: 164–170
   PubMed Web of Science ®Google Scholar
• Mersch-Sundermanna, V, Knasmüller S, XJ W, Darraoudi F, Fekadu K, Kassie F. Use of a human-derived liver cell line for the detection of cytoprotective, antigenotoxic and cogenotoxic agents. Toxicology 2004;198:329–340.
   PubMed Web of Science ®Google Scholar
• Singh NP, Stephens RE. Microgel electrophoresis: sensitivity, mechanisms, and DNA electrostretching. Mutat Res 1997; 383: 167–175
   PubMed Web of Science ®Google Scholar
• Natarajan AT, Darroudi F. Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens. Mutagenesis 1991; 5: 399–403
   Google Scholar
• Bass DA, Parce JW, Dechatelet LR, Szejda P, Seeds MC, Thomas M. Flow cytometry studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J Immunol 1983; 130: 1910–1917
   PubMed Web of Science ®Google Scholar
• Halliwell B, Whiteman M. Measuring reactive species and oxidative damage in vivo and cell culture. How should you do it and what does it mean?. Br J Pharmacol 2004; 142: 231–255
   PubMed Web of Science ®Google Scholar
• Leal LKAM, Junior HVN, Cunhaa GMA, Moraes MO, Pessoa C, Oliveira RA, Silveira ER, Canuto KM, Viana GSB. Amburoside A, a glucoside from Amburana cearensis, protects mesencephalic cells against 6-hydroxydopamine-induced neurotoxicity. Neurosci Lett 2005; 388: 86–90
   PubMed Web of Science ®Google Scholar
• Hissin PJ, Hilf RA. Fluorimetric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem 1976; 74: 214–226
   PubMed Web of Science ®Google Scholar
• Grasso S, Siracusa L, Spatafora C, Renis M. Hydroxytyrosol lipophilic analogues: enzymatic synthesis radical scavenging activity and DNA oxidative damage protection. Bioorg Chem 2007; 35: 137–152
   PubMed Web of Science ®Google Scholar
• Quiles JL, Farquharson AJ, Simpson DK, Grant I, Wahle KW. Olive oil phenolics: effects on DNA oxidation and redox enzyme mRNA in prostate cells. Br J Nutr 2002; 88: 225–234
   PubMedGoogle Scholar
• Stupans I, Kirlich AL, Tuck KJ, Hayball P. Comparison of radical scavenging effect, inhibition of microsomal oxygen free radical generation, and serum lipoprotein oxidation of several natural antioxidants. J Agric Food Chem 2002; 50: 2462–2469
   Web of Science ®Google Scholar
• Stiborova M, Martinek V, Rydlova H, Hodek P, Frei E. Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes. Cancer Res 2002; 62: 5678–5684
   PubMed Web of Science ®Google Scholar
• Knowles BB, Howe CC, Aden DP. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 1980; 209: 497–499
   PubMed Web of Science ®Google Scholar
• Fairbairn DW, Olive PL, O'Meill KL. The comt assay: a comprehensive review. Mutat Res 1995; 339: 37–59
   PubMed Web of Science ®Google Scholar
• Kirsch VM, Elhajouji A, Cundari E, Van HP. The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction. Mutat Res 1997; 392: 19–30
   PubMed Web of Science ®Google Scholar
• Sies H. Oxidative stress, oxidants, and antioxidants. London and New York: Academic Press; 1991.
   Google Scholar
• Mates JM. Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 2000; 153: 83–104
   PubMed Web of Science ®Google Scholar
• Haraguchi H, Ishikawa H, Sanchez Y, Oqura T, Kubo Y, Kubo I. Antioxidative constituents in Heterotheca inuloides. Bioorg Med Chem 1998; 6: 339–347
   PubMed Web of Science ®Google Scholar
• Stiborava M, Frei E, Schmeiser HH, Wiessler M, Hradec J. Mechanism of formation and 32P-postlabeling of DNA adducts derived from peroxidative activation of carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I). Carcinogenisis 1990; 11: 1843–1848
   PubMed Web of Science ®Google Scholar
• M(ller P, Wallin H. Genotoxic hazards of azo pigments and other colorants related to 1-phenylazo-2-hydroxynaphthalene. Mutat Res 2000; 462: 13–30
   PubMed Web of Science ®Google Scholar
• CaterinaM, Fulvio DR, Valeria C, Adriana B, Stefania DA, Patrizia G, Vincenzo Z. Biological effects of hydroxytyrosol, a polyphenol from olive oil endowed with antioxidant activity. In: Zappoa V Advances in nutrition and cancer. New York: Kluwer Academic/Plenum Publishers; 1999.
   Google Scholar
• Alia M, Ramos S, Mateos R, Bravo L, Goya L. Response of the antioxidant defense system to t-butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2). J Biochem Mol Toxicol 2005; 19: 119–128
   PubMed Web of Science ®Google Scholar
• Scharf G, Prustomersky S, Knasmuller S, Schulte HR, Huber WW. Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2. Nutr Cancer 2003; 45: 74–83
   PubMed Web of Science ®Google Scholar
• Sai K, Umemura T, Takagi A, Hasegawa R, Kurokawa Y. The protective role of glutathione, cysteine and Vitamin C against oxidative DNA damage induced in rat kidney by potaassium bromate. Jpn J Cancer Res 1992; 1: 45–51
   Google Scholar
• Kasai H, Nishimura S. Hydroxylation of deoxyguanosine at the C8 position by ascorbic acid and other reducing agents. Nucleic Acids Res 1984; 12: 2137–2145
   PubMed Web of Science ®Google Scholar
• Reliene R, Schiestl RH. Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis 2006; 27: 240–244
   PubMed Web of Science ®Google Scholar