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Research Article

Preparation and Analgesic Activity of Eudragit RS100® Microparticles Containing Diflunisal

Pages 35-45 | Published online: 29 Sep 2008

REFERENCES

  • Goto, S., Kawata, M., Nakamura, M., Maekauwa, K., and Ayoama, T. 1986. Eudragit RS and RL (acrylic resins) microcapsules as pH insensitive and sustained release preparations of ketoprofen. J. Microencapsul. 3:293– 304.
  • Kawata, M., Nakamura, M., Goto, T., and Ayoama, T. 1968. Preparation and dissolution pattern of Eudragit RS microcapsule s containing ketoprofen. Chem. Pharm. Bull. 34:2618 – 2623.
  • Lehmann, K. 1989. Chemistry and application properties of polymethacry - late coating systems. In Aqueous Polymeric Coating for Pharmaceutica l Dosage Forms, ed. J. W. McGinity, p. 153. New York: Marcel Dekker.
  • Oth, M. P., and Mo¨es, A. J. 1989. Sustained release solid dispersions of indomethaci n with Eudragit RS and RL. Int. J. Pharm. 55:157– 164.
  • Palmieri, G. F., Lovato, D., and Martelli, S. 1988. New controlled-releas e ibuprofen tablets. Drug Dev. Ind. Pharm. 25:671– 677.
  • Vachon, M. G., and Nairn, J. G. 1995. Physiochemica l evaluation of acetyl- salicycal acid-Eudragit RS100 microspheres prepared using a solvent par- tition method. J. Microencapsul. 12:287– 305.
  • Kawashima, Y., Niwa, T., Handa, T., Takeuchi, H., Iwamoto, T., and Itoh, Y. 1989. Preparation of prolonged-releas e spherical micro-matrix of ibuprofen with acrylic polymer by the emulsion-solven t diffusion method for improv- ing bioavailability. Chem. Pharm. Bull. 37:425– 429.
  • Kawashima, Y., Iwamoto, T., Niwa, T., Takeuchi, H., and Itoh, Y. 1991. Preparation and characterisation of a new controlled release ibupro- fen suspension for improving suspendibilit y. Int. J. Pharm. 75:25– 36.
  • Cotton, M., and Hux, R. A. 1985. Diflunisal. In Analytical Profiles of Drugs Substances, ed. K. Florey, vol. 14, 491–526. Orlando, FL: Academic Press.
  • Kawashima, Y., Niwa, T., Handa, T., Takeuchi, H., Iwamoto, T., and Itoh, Y. 1989. Preparation of controlled-releas e microsphere s of ibuprofen with an acrylic polymer by novel quasi-emulsion solvent diffusion method. J. Pharm. Sci. 78:68– 72.
  • Nastruzzi, C., Esposito, E., Cortesi, R., Gambari, R., and Menegatti, E. 1993. Kinetics of bromocriptine release from microspheres: comparative analysis between different in vitro models. J. Microencapsul. 11:565– 574.
  • Meunier, C. J., Burton, J., Cumps, J., and Verbeeck, R. K. 1998. Evaluation of the formalin test to assess the analgesic activity of diflunisal in the rat. Eur. J. Pharm. Sci. 6:307 – 312.
  • Rosland, J. H., Tjølsen, A., Maehle B., and Hole, K. 1990. The formalin test in mice—effect of formalin concentration. Pain 42:235 – 242.
  • Sawynok, J., Reid, A., and Poon, A. 1998. Peripheral antinociceptive effect of adenosine kinase inhibitor, with augmentatio n by an adenosine inhibitor, in the rat formalin test. Pain 74:75– 81.
  • Tjølsen, A., Berger, O. G., Hunskaar, S., Rosland, J. H., and Hole, K. 1992. The formalin test: an evaluation of the method. Pain 51:5– 17.
  • Kawashima, Y., Niwa, T., Takeuchi, H., Hino, T., and Itoh, Y. 1992. Con- trolled of prolonged drug release and compression properties of ibuprofen microsponges with acrylic polymer, Eudragit RS, by changing their intra- particle porosity. Chem. Pharm. Bull 40:196 – 201.
  • Palmieri, G. F., Wehrle`, P., and Stamm, A. 1994. Evaluation of spray drying as a method to prepare microparticles for controlled drug release. Drug Dev. Ind. Pharm. 20:2859– 2879.
  • Pignatello, R., Vandelli, M. A., Giunchedi, P., and Puglisi, G. 1997. Properties of tolmetin-loaded Eudragit RL100 and Eudragit RS100 mi- croparticles prepared by different techniques. S.T.P. Pharma Sci. 7:148– 157.
  • Heun, G., Lambov, N., and Gro¨ning, R. 1989. Experimental and molecular modelling studies on interactions between drugs and Eudragit°R RL/RS resins in aqueous environment. Pharm. Acta Helvetiae 73:57.
  • Jenquin, M. R., Liebowitz, S. M., Sarabia, R. E., and McGinity, J. W. 1990. Physical and chemical factors influencing the release of drugs from acrylic resin film. J. Pharm. Sci. 79:811– 816.
  • Otsuka, M., Onoe, M., and Matsuda, Y. 1993. Hygroscopi c stability and dissolution properties of spray-dried solid dispersions of furosemide with Eudragit. J. Pharm. Sci. 82:32– 38.
  • Pignatello, R., Consoli, P., and Puglisi, G. 2000. In vitro release kinetics of tolmetin from tabletted Eudragit microparticles. J. Microencapsul. 17: 373–383.
  • Kawashima, Y., Iwamoto, T., Niwa, T., Takeuchi, H., and Hino, T. 1993. Size control of ibuprofen microspheres with an acrylic polymer by changing the pH in an aqueous dispersion medium and its mechanism. Chem. Pharm. Bull. 41:191– 195.
  • Perumal, D., Dangor, C. M., Alcock, R. S., Hurbans, N., and Moopanar, K. R. 1999. Effect of formulation variables on in vitro drug release and micrometric properties of modified release ibuprofen microspheres. J. Microencapsul. 16:475– 487.
  • Okor, R. S. 1989. Solute adsorption and concentration-dependen t perme- ability in certain polymer films. J. Pharm. Pharmacol. 41:483– 484.
  • Jenquin, M. R., and McGinity, J. W. 1994. Characterization of acrylic resin matrix films and mechanisms of drug-polyme r interactions. Int. J. Pharm. 101:23– 34.
  • Khalil, E., and Sallam, A. 1999. Interaction of two diclofenac acid salts with copolymer s of ammoniomethacrylate: effect of additives and release profiles. Drug Dev. Ind. Pharm. 25:419– 427.
  • Ritger, P. L., and Peppas, N. A. 1987. A simple equation for description of solute release. I: Fickian and non-Fickian release from non-swellabl e devices in the form of slabs, spheres, cylinders or discs. J. Cont. Release 5:23– 26.

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