490
Views
22
CrossRef citations to date
0
Altmetric
ARTICLES

Single robust RP-HPLC analytical method for quantification of curcuminoids in commercial turmeric products, Ayurvedic medicines, and nanovesicular systems

, , , &

References

  • Ishita, C.; Khaushik, B. Turmeric and Curcumin: Biological Actions and Medical Applications. Curr. Sci. 2004, 87, 44–50.
  • Ali, I.; Haque, A.; Saleem, K. Separation and Identification of Curcuminoids in Turmeric Powder by HPLC using Phenyl Column. Anal. Methods 2014, 6, 2526–2636.
  • Ali, I.; Haque, A.; Saleem, K.; Hsieh, M. F. Curcumin-I Knoevenagel’s Condensates and their Schiff’s Bases as Anticancer Agents: Synthesis, Pharmacological and Simulation Studies. Bioorg. Med. Chem. 2013, 21, 3808–3820.
  • Ali, I.; Saleem, K.; Wesselinova, D.; Haque, A. Synthesis, DNA Binding, Hemolytic, and Anti-cancer Assays of Curcumin I-based Ligands and their Ruthenium(III) Complexes. Med. Chem. Res. 2013, 22, 1386–1398.
  • Singh, P.; Pandey, K.; Rizvi, S. Curcumin: The Yellow Molecule with Pleiotropic Biological Effects. Lett. Drug Des. Discov. 2015, 13, 170–177.
  • Goel, A.; Jhurani, S.; Aggarwal, B. B. Multi-targeted Therapy by Curcumin: How Spicy is it? Mol. Nutr. Food Res. 2008, 52, 1010–1030.
  • Turmeric: Curcuma longa Benefits, Usage, Dose, Side Effects. http://easyayurveda.com/2013/10/23/turmeric-curcuma-longa-benefits-usage-dose-side-effects/ (accessed December 10, 2016).
  • Amalraj, A.; Pius, A.; Gopi, S.; Gopi, S. Biological Activities of Curcuminoids, Other Biomolecules from Turmeric and Their Derivatives – A Review. J. Tradit. Compl. Med. 2017, 7, 205–233. doi:10.1016/j.jtcme.2016.05.005
  • Ahmed, T.; Gilani, A. H. Therapeutic Potential of Turmeric in Alzheimer’s Disease: Curcumin or Curcuminoids? Phyther. Res. 2014, 28, 517–525.
  • Anand, P.; Thomas, S. G.; Kunnumakkara, A. B.; Sundaram, C.; Harikumar, K. B.; Sung, B.; Tharakan, S. T.; Misra, K.; Priyadarsini, I. K.; Rajasekharan, K. N.; Aggarwal, B. B. Biological Activities of Curcumin and Its Analogues (Congeners) Made by Man and Mother Nature. Biochem. Pharmacol. 2008, 76, 1590–1611.
  • Sandur, S. K.; Pandey, M. K.; Sung, B.; Ahn, K. S.; Murakami, A.; Sethi, G.; Limtrakul, P.; Badmaev, V.; Aggarwal, B. B. Curcumin, Demethoxycurcumin, Bisdemethoxycurcumin, Tetrahydrocurcumin and Turmerones Differentially Regulate Anti-inflammatory and Anti-proliferative Responses through a ROS-independent Mechanism. Carcinogenesis 2007, 28, 1765–1773.
  • Anand, P.; Kunnumakkara, A. B.; Newman, R. A.; Aggarwal, B. B. Bioavailability of Curcumin: Problems and Promises. Mol. Pharm. 2007, 4, 807–818.
  • Mohanty, C.; Das, M.; Sahoo, S. K. Emerging Role of Nanocarriers to Increase the Solubility and Bioavailability of Curcumin. Expert Opin. Drug Deliv. 2012, 9, 1347–1364.
  • Mbah, C. C.; Builders, P. F.; Attama, A. A. Nanovesicular Carriers as Alternative Drug Delivery Systems: Ethosomes in Focus. Expert Opin. Drug Deliv. 2014, 11, 45–59.
  • Kumar, A.; Pathak, K.; Bali, V. Ultra-adaptable Nanovesicular Systems: A Carrier for Systemic Delivery of Therapeutic Agents. Drug Discov. Today 2012, 17, 1233–1241.
  • Rohman, A. Analysis of Curcuminoids in Food and Pharmaceutical Products. Int. Food Res. J. 2012, 19, 19–27.
  • Osorio-Tobon, J. F.; Carvalho, P. I. N.; Barbero, G. F.; Nogueira, G. C.; Rostagno, M. A.; de Almeida Meireles, M. A. Fast Analysis of Curcuminoids from Turmeric (Curcuma longa L.) by High-performance Liquid Chromatography using a Fused-core Column. Food Chem. 2016, 200, 167–174.
  • Li, R.; Xiang, C.; Ye, M.; Li, H. F.; Zhang, X.; Guo, D. A. Qualitative and Quantitative Analysis of Curcuminoids in Herbal Medicines Derived from Curcuma Species. Food Chem. 2011, 126, 1890–1895.
  • Li, H. X.; Zhang, H. L.; Zhang, N.; Wang, N.; Yang, Y.; Zhang, Z. Z. Isolation of Three Curcuminoids for Stability and Simultaneous Determination of Only Using One Single Standard Substance in Turmeric Colour Principles by HPLC with Ternary Gradient System. LWT - Food Sci. Technol. 2014, 57, 446–451.
  • Long, Y.; Zhang, W.; Wang, F.; Chen, Z. Simultaneous Determination of Three Curcuminoids in Curcuma longa L. by High Performance Liquid Chromatography Coupled with Electrochemical Detection. J. Pharm. Anal. 2014, 4, 325–330.
  • Jangle, R. D.; Thorat, B. N. Reversed-phase High-performance Liquid Chromatography Method for Analysis of Curcuminoids and Curcuminoid-loaded Liposome Formulation. Indian J. Pharm. Sci. 2013, 75, 60–66.
  • Jayaprakasha, G. K.; Jagan, L.; Rao, M.; Sakariah, K. K. Improved HPLC Method for the Determination of Curcumin, Demethoxycurcumin, and Bisdemethoxycurcumin. J. Agric. Food Chem. 2002, 50, 3668–3672.
  • Lee, J. H.; Choung, M. G. Determination of Curcuminoid Colouring Principles in Commercial Foods by HPLC. Food Chem. 2011, 124, 1217–1222.
  • Syed, H. K.; Liew, K. Bi.; Loh, G. O. K.; Peh, K. K. Stability Indicating HPLC-UV Method for Detection of Curcumin in Curcuma longa Extract and Emulsion Formulation. Food Chem. 2015, 170, 321–326.
  • Castro Frabel do Nascimento, T.; Meza Casa, D.; Facco Dalmolin, L.; Cristina de Mattos, A.; Maissar Khalil, N.; Mara Mainardes, R. Development and Validation of an HPLC Method Using Fluorescence Detection for the Quantitative Determination of Curcumin in PLGA and PLGA-PEG Nanoparticles. Curr. Pharm. Anal. 2012, 8, 324–333.
  • Mazzarino, L.; Bellettini, I. C.; Minatti, E.; Lemos-Senna, E. Development and Validation of a Fluorimetric Method to Determine Curcumin in Lipid and Polymeric Nanocapsule Suspensions. Brazilian J. Pharm. Sci. 2010, 46, 219–226.
  • da Silva-Buzanello, R. A.; Ferro, A. C.; Bona, E.; Cardozo-Filho, L.; de Araújo, P. H. H.; Leimann, F. V.; Gonçalves, O. H. Validation of an Ultraviolet-visible (UV-Vis) Technique for the Quantitative Determination of Curcumin in Poly(L-Lactic Acid) Nanoparticles. Food Chem. 2015, 172, 99–104.
  • ICH. ICH Harmonised Tripartite Guideline: Validation of Analytical Procedures: Text and Methodology (Q2R1). Geneva: ICH, 2005.
  • Guo, F.; Wang, J.; Ma, M.; Tan, F.; Li, N. Skin Targeted Lipid Vesicles as Novel Nano-carrier of Ketoconazole: Characterization, In Vitro and In Vivo Evaluation. J. Mater. Sci. Mater. Med. 2015, 26, 1–13.
  • Meng, S.; Chen, Z.; Yang, L.; Zhang, W.; Liu, D.; Guo, J.; Guan, Y.; Li, J. Enhanced Transdermal Bioavailability of Testosterone Propionate via Surfactant-modified Ethosomes. Int. J. Nanomed. 2013, 8, 3051–3060.
  • Li, S.; Yuan, W.; Deng, G.; Wang, P. Chemical Composition and Product Quality Control of Turmeric (Curcuma longa L.). Pharm. Crop. 2011, 2, 28–54.
  • Choi, J.; Cho, S.; Yun, J.; Yu, Y.; Cho, C. Ethosomes and Transfersomes for Topical Delivery of Ginsenoside Rh1 from Red Ginseng : Characterization and In Vitro Evaluation. J. Nanosci. Nanotechnol. 2015, 15, 5660–5662.
  • Bos, R.; Windono, T.; Woerdenbag, H. J.; Boersma, Y. L.; Koulman, A.; Kayser, O. HPLC-Photodiode Array Detection Analysis of Curcuminoids in Curcuma Species Indigenous to Indonesia. Phytochem. Anal. 2007, 18, 118–122.
  • Malasoni, R.; Srivastava, A.; Pandey, R. R.; Srivastava, P. K.; Dwivedi, A. K. Development and Validation of Improved HPLC Method for the Quantitative Determination of Curcuminoids in Herbal Medicament. J. Sci. Ind. Res. (India). 2013, 72, 88–91.
  • Jadhav, B. K.; Mahadik, K. R.; Paradkar, A. R. Development and Validation of Improved Reversed Phase-HPLC Method for Simultaneous Determination of Curcumin, Demethoxycurcumin and Bis-Demethoxycurcumin. Chromatographia 2007, 65, 483–488.
  • Wichitnithad, W.; Jongaroonngamsang, N.; Pummangura, S.; Rojsitthisak, P. A Simple Isocratic HPLC Method for the Simultaneous Determination of Curcuminoids in Commercial Turmeric Extracts. Phytochem. Anal. 2009, 20, 314–319.
  • Zhang, J.; Jinnai, S.; Ikeda, R.; Wada, M.; Hayashida, S.; Nakashima, K. A Simple HPLC-Fluorescence Method for Quantitation of Curcuminoids and its Application to Turmeric Products. Anal. Sci. 2009, 25, 385–388.
  • Koop, H. S.; De Freitas, R. A.; De Souza, L. M.; Martinez, G. R.; Silveira, J. L. M. Development and Validation of a RP-HPLC-PDA Method for Determination of Curcuminoids in Microemulsions. Chromatographia 2013, 76, 1041–1048.
  • Peret-Almeida, L.; Cherubino, A. P. F.; Alves, R. J.; Dufossé, L.; Gloria, M. B. A. Separation and Determination of the Physico-chemical Characteristics of Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin. Food Res. Int. 2005, 38, 1039–1044.
  • Hsu, Y. C.; Weng, H. C.; Lin, S.; Chien, Y. W. Curcuminoids-cellular Uptake by Human Primary Colon Cancer Cells as Quantitated by a Sensitive HPLC Assay and Its Relation with the Inhibition of Proliferation and Apoptosis. J. Agric. Food Chem. 2007, 55, 8213–8222.
  • Naidu, M. M.; Shyamala, B. N.; Manjunatha, J. R.; Sulochanamma, G.; Srinivas, P. Simple HPLC Method for Resolution of Curcuminoids with Antioxidant Potential. J. Food Sci. 2009, 74, 312–318.
  • Cheng, J.; Weijun, K.; Yun, L.; Jiabo, W.; Haitao, W.; Qingmiao, L.; Xiaohe, X. Development and Validation of UPLC Method for Quality Control of Curcuma longa Linn.: Fast Simultaneous Quantitation of Three Curcuminoids. J. Pharm. Biomed. Anal. 2010, 53, 43–49.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.