Advanced search
Publication Cover
Pharmaceutical Development and Technology Volume 23, 2018 - Issue 2
Submit an article Journal homepage
237
Views
3
CrossRef citations to date
0
Altmetric
Research Article

The influence of stevia on the flow, shear and compression behavior of sorbitol, a pharmaceutical excipient for direct compression

Hana HurychováFaculty of Pharmacy, Department of Pharmaceutical Technology, Charles University, Hradec Kralove, Czech Republic; View further author information
,
Pavel OndrejčekFaculty of Pharmacy, Department of Pharmaceutical Technology, Charles University, Hradec Kralove, Czech Republic; View further author information
,
Zdenka ŠklubalováFaculty of Pharmacy, Department of Pharmaceutical Technology, Charles University, Hradec Kralove, Czech Republic; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-9314-705XView further author information
ORCID Icon,
Barbora VraníkováFaculty of Pharmacy, Department of Pharmaceutical Technology, Charles University, Hradec Kralove, Czech Republic; View further author information
&
Tomáš SvěrákFaculty of Chemistry, Institute of Materials Science, University of Technology, Brno, Czech RepublicView further author information
Pages 125-131 | Received 13 Dec 2016, Accepted 29 Mar 2017, Published online: 13 Apr 2017

References

  • Abdullah EC, Geldart D. 1999. The use of bulk density measurements as flowability indicators. Powder Technol. 102:151–165.
  • Augsburger LL, Hoag SW. 2008. Pharmaceutical dosage forms: tablets. Volume 1: unit operations and mechanical properties. New York: Informa Healthcare, Inc.
  • Bolhuis GK, Chowhan ZT. 1996. Materials for direct compaction. In: Alderborn G, Nyström Ch, editors. Pharmaceutical powder compaction technology. New York: Marcel Dekker, Inc.; p. 419–500.
  • Bolhuis GK, Rexwinkel EG, Zuurman K. 2009. Polyols as filler-binders for disintegrating tablets prepared by direct compaction. Drug Dev Ind Pharm. 35:671–677.
  • Bastos MO, Friedrich RB, Beck RCR. 2008. Effects of filler-binders and lubricants on physicochemical properties of tablets obtained by direct compression: a 22 factorial design. Lat Am J Pharm. 27:578–583.
  • Caracostas MC, Curry LL, Boileau AC, Brusick DJ. 2008. Overview: the history, technical function and safety of rebaudioside A, a naturally occurring steviol glycoside, for use in food and beverages. Food Chem Toxicol. 46:S1–S10.
  • Carr RL. 1965. Evaluating flow properties of solids. Chem Eng. 72:163–168.
  • Crouter A, Briens L. 2013. The effect of moisture on the flowability of pharmaceutical excipients. AAPS Pharm Sci Tech. 15:65–74.
  • Fell JT, Newton JM. 1970. Determination of tablet strength by the diametral-compression test. J Pharm Sci. 59:688–691.
  • Gad SC. 2008. Pharmaceutical manufacturing handbook. Production and processes. New Jersey: John Wiley & Sons, Inc.
  • Geldart D, Abdullah EC, Hassanpour A, Nwoke LC, Wouters I. 2006. Characterization of powder flowability using measurement of angle of repose. China Particuol. 4:104–107.
  • Goyal SK, Samsher, Goyal RK. 2010. Stevia (Stevia rebaudiana) a bio-sweetener: a review. Int J Food Sci Nutr. 61:1–10.
  • Grembecka M. 2015. Sugar alcohols – their role in the modern world of sweeteners: a review. Eur Food Res Technol. 241:1–14.
  • McGlinchey D. 2005. Characterization of bulk solids. London: Blackwell Publishing Ltd.
  • Mullarney MP, Hancock BC, Carlson GT, Ladipo DD, Langdon BA. 2003. The powder flow and compact mechanical properties of sucrose and three high-intensity sweeteners used in chewable tablets. Int J Pharm. 257:227–236.
  • Nabors LO. 2012. Alternative sweeteners. Florida: Taylor & Francis Group, LLC.
  • Nedderman RM, Tüzün U, Savage SB, Houlsby GT. 1982. The flow of granular materials. I: discharge rate from hoppers. Chem Eng Sci. 37:1597–1609.
  • O’Donnell K, Kearsley MW. 2012. Sweeteners and sugar alternatives in food technology. New Jersey: John Wiley & Sons, Ltd.
  • Parikh DM. 2005. Handbook of pharmaceutical granulation technology. Florida: Taylor & Francis Group, LLC.
  • Podczeck F, Miah Y. 1996. The influence of particle size and shape on the angle of internal friction and the flow factor of unlubricated and lubricated powders. Int J Pharm. 144:187–194.
  • Prescott JK, Barnum RA. 2000. On powder flowability. Pharm Technol. 24:60–84.
  • Ragnarsson G. 1996. Pharmaceutical powder compaction technology. In: Alderborn G, Nyström Ch, editors. Pharmaceutical powder compaction technology. New York: Marcel Dekker, Inc.; p. 77–97.
  • Qiu Y, Chen Y, Zhang G, Liu L, Porter W. 2009. Developing solid oral dosage forms. Amsterdam: Elsevier Inc.
  • Schulze D. 2008. Powders and bulk solids: behavior, characterization, storage and flow. Berlin: Springer-Verlag GmbH.
  • Schwedes J. 2003. Review on testers for measuring flow properties of bulk solids. Granul Matter. 5:1–43.
  • Sohi H, Sultana Y, Khar RK. 2004. Taste masking technologies in oral pharmaceuticals: recent developments and approaches. Drug Dev Ind Pharm. 30:429–448.
  • Šklubalová Z, Hurychová H. 2015. The effect of the size of a conical hopper aperture on the parameters of the flow equation of sorbitol and its size fractions. Čes Slov Farm. 64:14–18.
  • Traina K, Cloots R, Bontempi S, Lumay G, Vandewalle N, Boschini F. 2013. Flow abilities of powders and granular materials evidenced from dynamical tap density measurement. Powder Technol. 235:842–852.
  • Xie X, Puri VM. 2006. Uniformity of powder die filling using a feed shoe: a review. Part Sci Technol. 24:411–426.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.