Cyproterone acetate-loaded nanostructured lipid carriers: effect of particle size on skin penetration and follicular targeting

References

• Adib ZM, Ghanbarzadeh S, Kouhsoltani M, Khosroshahi AY, Hamishehkar H. 2016. The effect of particle size on the deposition of solid lipid nanoparticles in different skin layers: a histological study. Adv Pharm Bull. 6:31.
   PubMed Web of Science ®Google Scholar
• Agrawal U, Gupta M, Vyas S. 2015. Capsaicin delivery into the skin with lipidic nanoparticles for the treatment of psoriasis. Artif Cells Nanomed Biotechnol. 43:33–39.
   PubMed Web of Science ®Google Scholar
• Arıca Yegin B, Benoît J-P, Lamprecht A. 2006. Paclitaxel-loaded lipid nanoparticles prepared by solvent injection or ultrasound emulsification. Drug Dev Ind Pharm. 32:1089–1094.
   PubMed Web of Science ®Google Scholar
• Azadi A, Hamidi M, Rouini M-R. 2013. Methotrexate-loaded chitosan nanogels as 'Trojan Horses' for drug delivery to brain: preparation and in vitro/in vivo characterization. Int J Biol Macromol. 62:523–530.
   PubMed Web of Science ®Google Scholar
• Beloqui A, Solinis MA, Rodriguez-Gascon A, Almeida AJ, Preat V. 2016. Nanostructured lipid carriers: promising drug delivery systems for future clinics. Nanomedicine. 12:143–161.
   PubMed Web of Science ®Google Scholar
• Chandross R, Bordner J. 1974. The crystal structure of a potent anti-androgen: cyproterone acetate (6-chloro-17-hydroxy-1α, 2α-methylenepregna-4, 6-diene-3, 20-dione acetate). Acta Crystallogr B Struct Crystallogr Cryst Chem. 30:1581–1585.
   Google Scholar
• Chauhan H, Mohapatra S, Munt DJ, Chandratre S, Dash A. 2016. Physical-chemical characterization and formulation considerations for solid lipid nanoparticles. AAPS PharmSciTech. 17:640–651.
   PubMed Web of Science ®Google Scholar
• Chen D-B, Yang T-z, Lu W-L, Zhang Q. 2001. In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel. Chem Pharm Bull. 49:1444–1447.
   PubMed Web of Science ®Google Scholar
• Chen J, Wei N, Lopez-Garcia M, Ambrose D, Lee J, Annelin C, Peterson T. 2017. Development and evaluation of resveratrol, Vitamin E, and epigallocatechin gallate loaded lipid nanoparticles for skin care applications. Eur J Pharm Biopharm. 117:286–291.
   PubMed Web of Science ®Google Scholar
• Chen W, Palazzo A, Hennink WE, Kok RJ. 2017. Effect of particle size on drug loading and release kinetics of gefitinib-loaded PLGA microspheres. Mol Pharm. 14:459–467.
   PubMedGoogle Scholar
• Chetoni P, Burgalassi S, Monti D, Tampucci S, Tullio V, Cuffini AM, Muntoni E, Spagnolo R, Zara GP, Cavalli R. 2016. Solid lipid nanoparticles as promising tool for intraocular tobramycin delivery: pharmacokinetic studies on rabbits. Eur J Pharm Biopharm. 109:214–223.
   PubMed Web of Science ®Google Scholar
• Cipolla D, Shekunov B, Blanchard J, Hickey A. 2014. Lipid-based carriers for pulmonary products: preclinical development and case studies in humans. Adv Drug Deliv Rev. 75:53–80.
   PubMed Web of Science ®Google Scholar
• Dal Magro R, Ornaghi F, Cambianica I, Beretta S, Re F, Musicanti C, Rigolio R, Donzelli E, Canta A, Ballarini E. 2017. ApoE-modified solid lipid nanoparticles: a feasible strategy to cross the blood-brain barrier. J Control Release. 249:103–110.
   PubMed Web of Science ®Google Scholar
• Das S, Ng WK, Tan RB. 2012. Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs? Eur J Pharm Sci. 47:139–151.
   PubMed Web of Science ®Google Scholar
• Doktorovova S, Kovacevic AB, Garcia ML, Souto EB. 2016. Preclinical safety of solid lipid nanoparticles and nanostructured lipid carriers: current evidence from in vitro and in vivo evaluation. Eur J Pharm Biopharm. 108:235–252.
   PubMed Web of Science ®Google Scholar
• Fang C-L, A Al-Suwayeh S, Fang J-Y. 2013. Nanostructured lipid carriers (NLCs) for drug delivery and targeting. Recent Pat Nanotechnol. 7:41–55.
   PubMed Web of Science ®Google Scholar
• Fernandes B, Silva R, Ribeiro A, Matamá T, Gomes A, Cavaco ‐, Paulo A. 2015. Improved poly (D,L-lactide) nanoparticles-based formulation for hair follicle targeting. Int J Cosmet Sci. 37:282–290.
   PubMed Web of Science ®Google Scholar
• Fontana G, Maniscalco L, Schillaci D, Cavallaro G, Giammona G. 2005. Solid lipid nanoparticles containing tamoxifen characterization and in vitro antitumoral activity. Drug Deliv. 12:385–392.
   PubMed Web of Science ®Google Scholar
• Garud A, Singh D, Garud N. 2012. Solid lipid nanoparticles (SLN): Method, characterization and applications. International Current Pharmaceutical Journal. 1(11):384–393.
   Google Scholar
• Ghasemiyeh P, Azadi A, Daneshamouz S, Samani SM. 2017. Cyproterone acetate-loaded solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs): preparation and optimization. Trends Pharm Sci. 3:275–286.
   Google Scholar
• Ghasemiyeh P, Mohammadi-Samani S. 2018. Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: applications, advantages and disadvantages. Res Pharm Sci. 13:288.
   PubMed Web of Science ®Google Scholar
• Hou D, Xie C, Huang K, Zhu C. 2003. The production and characteristics of solid lipid nanoparticles (SLNs). Biomaterials. 24:1781–1785.
   PubMed Web of Science ®Google Scholar
• Hu C, Qian A, Wang Q, Xu F, He Y, Xu J, Xia Y, Xia Q. 2016. Industrialization of lipid nanoparticles: from laboratory-scale to large-scale production line. Eur J Pharm Biopharm. 109:206–213.
   PubMed Web of Science ®Google Scholar
• Jaiswal P, Gidwani B, Vyas A. 2016. Nanostructured lipid carriers and their current application in targeted drug delivery. Artif Cells Nanomed Biotechnol. 44:27–40.
   PubMed Web of Science ®Google Scholar
• Kelidari H, Saeedi M, Akbari J, Morteza-Semnani K, Gill P, Valizadeh H, Nokhodchi A. 2015. Formulation optimization and in vitro skin penetration of spironolactone loaded solid lipid nanoparticles. Colloids Surf B Biointerfaces. 128:473–479.
   PubMed Web of Science ®Google Scholar
• Kelidari H, Saeedi M, Akbari J, Morteza-Semnani K, Valizadeh H, Maniruzzaman M, Farmoudeh A, Nokhodchi A. 2017. Development and optimisation of spironolactone nanoparticles for enhanced dissolution rates and stability. AAPS PharmSciTech. 18:1469–1474.
   PubMed Web of Science ®Google Scholar
• Korsmeyer RW, Gurny R, Doelker E, Buri P, Peppas NA. 1983. Mechanisms of solute release from porous hydrophilic polymers. Int J Pharm. 15:25–35.
   Web of Science ®Google Scholar
• Korsmeyer RW, Peppas NA. 1981. Effect of the morphology of hydrophilic polymeric matrices on the diffusion and release of water soluble drugs. J Memb Sci. 9:211–227.
   Web of Science ®Google Scholar
• Lademann J, Patzelt A, Richter H, Antoniou C, Sterry W, Knorr F. 2009. Determination of the cuticula thickness of human and porcine hairs and their potential influence on the penetration of nanoparticles into the hair follicles. J Biomed Opt. 14:021014.
   PubMed Web of Science ®Google Scholar
• Lauterbach A, Müller-Goymann CC. 2014. Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream. Eur J Pharm Biopharm. 88:614–624.
   PubMed Web of Science ®Google Scholar
• Lauterbach A, Muller-Goymann CC. 2015. Applications and limitations of lipid nanoparticles in dermal and transdermal drug delivery via the follicular route. Eur J Pharm Biopharm. 97:152–163.
   PubMed Web of Science ®Google Scholar
• Liu D, Liu Z, Wang L, Zhang C, Zhang N. 2011. Nanostructured lipid carriers as novel carrier for parenteral delivery of docetaxel. Colloids Surf B Biointerfaces. 85:262–269.
   PubMed Web of Science ®Google Scholar
• Liu J, Hu W, Chen H, Ni Q, Xu H, Yang X. 2007. Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery. Int J Pharm. 328:191–195.
   PubMed Web of Science ®Google Scholar
• Luo Y, Chen D, Ren L, Zhao X, Qin J. 2006. Solid lipid nanoparticles for enhancing vinpocetine's oral bioavailability. J Control Release. 114:53–59.
   PubMed Web of Science ®Google Scholar
• Mohammadi-Samani S, Jalali F, Tavakoli S, Ahmadi F. 2014. Solid lipid microparticles of lamotrigine: an injectable controlled release system for local delivery in nerve injuries. J Drug Deliv Sci Technol. 24:367–372.
   Web of Science ®Google Scholar
• Mohammadi-Samani S, Montaseri H, Jamshidnejad M. 2009. Preparation and evaluation of cyproterone acetate liposome for topical drug delivery. Iran J Pharm Sci. 5:199–204.
   Google Scholar
• Mojahedian MM, Daneshamouz S, Samani SM, Zargaran A. 2013. A novel method to produce solid lipid nanoparticles using n-butanol as an additional co-surfactant according to the o/w microemulsion quenching technique. Chem Phys Lipids. 174:32–38.
   PubMed Web of Science ®Google Scholar
• Monti D, Tampucci S, Burgalassi S, Chetoni P, Lenzi C, Pirone A, Mailland F. 2014. Topical formulations containing finasteride. Part I: in vitro permeation/penetration study and in vivo pharmacokinetics in hairless rat. J Pharm Sci. 103:2307–2314.
   PubMed Web of Science ®Google Scholar
• Müller RH, Mäder K, Gohla S. 2000. Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art. Eur J Pharm Biopharm. 50:161–177.
   PubMed Web of Science ®Google Scholar
• Müller R, Schwarz C, Zur Mühlen A, Mehnert W. 1994. Incorporation of lipophilic drugs and drug release profiles of solid lipid nanoparticles (SLN). Int Symp Control Release Bioact Mater. 21:146–147.
   Google Scholar
• Nnamani PO, Hansen S, Windbergs M, Lehr C-M. 2014. Development of artemether-loaded nanostructured lipid carrier (NLC) formulation for topical application. Int J Pharm. 477:208–217.
   PubMed Web of Science ®Google Scholar
• Park JH, Ban SJ, Ahmed T, Choi HS, Yoon HE, Yoon JH, Choi HK. 2015. Development of DH-I-180-3 loaded lipid nanoparticle for photodynamic therapy. Int J Pharm. 491:393–401.
   PubMedGoogle Scholar
• Patzelt A, Richter H, Knorr F, Schäfer U, Lehr C-M, Dähne L, Sterry W, Lademann J. 2011. Selective follicular targeting by modification of the particle sizes. J Control Release. 150:45–48.
   PubMed Web of Science ®Google Scholar
• Pradhan M, Singh D, Singh MR. 2017. Fabrication, optimization and characterization of triamcinolone acetonide loaded nanostructured lipid carriers for topical treatment of psoriasis: application of Box Behnken design, in vitro and ex vivo studies. J Drug Deliv Sci Technol. 41:325–333.
   Web of Science ®Google Scholar
• Puglia C, Lauro MR, Offerta A, Crascì L, Micicchè L, Panico AM, Bonina F, Puglisi G. 2017. Nanostructured lipid carriers (NLC) as vehicles for topical administration of sesamol: in vitro percutaneous absorption study and evaluation of antioxidant activity. Planta Med. 83:398–404.
   PubMed Web of Science ®Google Scholar
• Rancan F, Afraz Z, Combadiere B, Blume-Peytavi U, Vogt A. 2013. Hair follicle targeting with nanoparticles. Nanotechnology in dermatology. Amazon:Springer; p. 95–107.
   Google Scholar
• Sánchez-López E, Espina M, Doktorovova S, Souto EB, García ML. 2017. Lipid nanoparticles (SLN, NLC): Overcoming the anatomical and physiological barriers of the eye - Part II - Ocular drug-loaded lipid nanoparticles. Eur J Pharm Biopharm. 110:58–69.
   PubMed Web of Science ®Google Scholar
• Severino P, Andreani T, Macedo AS, Fangueiro JF, Santana MHA, Silva AM, Souto EB. 2012. Current state-of-art and new trends on lipid nanoparticles (SLN and NLC) for oral drug delivery. J Drug Deliv. 2012:1–10.
   Google Scholar
• Shah M. 2017. Solid lipid nanoparticles (SLN) for oral drug delivery: an overview. J Nanomed Nanosci. 2017(2):1–2. DOI: 10.29011/JNAN109-100009.
   Google Scholar
• Shah RM, Malherbe F, Eldridge D, Palombo EA, Harding IH. 2014. Physicochemical characterization of solid lipid nanoparticles (SLNs) prepared by a novel microemulsion technique. J Colloid Interface Sci. 428:286–294.
   PubMed Web of Science ®Google Scholar
• Shidhaye S, Vaidya R, Sutar S, Patwardhan A, Kadam V. 2008. Solid lipid nanoparticles and nanostructured lipid carriers-innovative generations of solid lipid carriers. Curr Drug Deliv. 5:324–331.
   PubMedGoogle Scholar
• Tampucci S, Burgalassi S, Chetoni P, Lenzi C, Pirone A, Mailland F, Caserini M, Monti D. 2014. Topical formulations containing finasteride. Part II: determination of finasteride penetration into hair follicles using the differential stripping technique. J Pharm Sci. 103:2323–2329.
   PubMed Web of Science ®Google Scholar
• Tokton N, Ounaroon A, Panichayupakaranant P, Tiyaboonchai W. 2014. Development of ellagic acid rich pomegranate peel extract loaded nanostructured lipid carriers (NLCS). Int J Pharm Pharm Sci. 6:259–265.
   Google Scholar
• Toll R, Jacobi U, Richter H, Lademann J, Schaefer H, Blume-Peytavi U. 2004. Penetration profile of microspheres in follicular targeting of terminal hair follicles. J Invest Dermatol. 123:168–176.
   PubMed Web of Science ®Google Scholar
• Trotta M, Debernardi F, Caputo O. 2003. Preparation of solid lipid nanoparticles by a solvent emulsification–diffusion technique. Int J Pharm. 257:153–160.
   PubMed Web of Science ®Google Scholar
• Tursilli R, Piel G, Delattre L, Scalia S. 2007. Solid lipid microparticles containing the sunscreen agent, octyl-dimethylaminobenzoate: effect of the vehicle. Eur J Pharm Biopharm. 66:483–487.
   PubMed Web of Science ®Google Scholar
• Wosicka-Frąckowiak H, Cal K, Stefanowska J, Główka E, Nowacka M, Struck-Lewicka W, Govedarica B, Pasikowska M, Dębowska R, Jesionowski T, et al. 2015. Roxithromycin-loaded lipid nanoparticles for follicular targeting. Int J Pharm. 495:807–815.
   PubMed Web of Science ®Google Scholar
• Zhang C, Peng F, Liu W, Wan J, Wan C, Xu H, Lam CW, Yang X. 2014. Nanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male rats. Int J Nanomedicine. 9:1049.
   PubMed Web of Science ®Google Scholar
• zur Mühlen A, Schwarz C, Mehnert W. 1998. Solid lipid nanoparticles (SLN) for controlled drug delivery-drug release and release mechanism. Eur J Pharm Biopharm. 45:149–155.
   PubMed Web of Science ®Google Scholar