379
Views
1
CrossRef citations to date
0
Altmetric
Research Articles

Chitosan-bovine serum albumin-Carbopol 940 nanogels for mupirocin dermal delivery: ex-vivo permeation and evaluation of cellular binding capacity via radiolabeling

ORCID Icon, ORCID Icon, ORCID Icon, , , ORCID Icon & ORCID Icon show all
Pages 852-866 | Received 16 Sep 2020, Accepted 22 Jun 2021, Published online: 11 Jul 2021

References

  • Aderibigbe B, Naki T. 2018. Design and efficacy of nanogels formulations for intranasal administration. Molecules. 23(6):1241.
  • Amrutiya N, Bajaj A, Madan M. 2009. Development of microsponges for topical delivery of mupirocin. AAPS PharmSciTech. 10(2):402–409.
  • Andrews GP, Gorman SP, Jones DS. 2005. Rheological characterisation of primary and binary interactive bioadhesive gels composed of cellulose derivatives designed as ophthalmic viscosurgical devices. Biomaterials. 26(5):571–580.
  • Andrews GP, Jones DS. 2006. Rheological characterization of bioadhesive binary polymeric systems designed as platforms for drug delivery implants. Biomacromolecules. 7(3):899–906.
  • Aslan C, Çelebi N, Değim İT, Atak A, Özer Ç. 2017. Development of interleukin-2 loaded chitosan-based nanogels using artificial neural networks and investigating the effects on wound healing in rats. AAPS PharmSciTech. 18(4):1019–1030.
  • Ay Şenyiğit Z, Karavana SY, Eraç B, Gürsel O, Limoncu MH, Baloğlu E. 2014. Evaluation of chitosan based vaginal bioadhesive gel formulations for antifungal drugs. Acta Pharm. 64(2):139–156.
  • Baloglu E, Karavana SY, Senyigit ZA, Guneri T. 2011. Rheological and mechanical properties of poloxamer mixtures as a mucoadhesive gel base. Pharm Dev Technol. 16(6):627–636.
  • Bayldon W, Narishetty S, De Rose G, Rothwell J, Mills PC. 2014. Effects of eight vehicles on transdermal lidocaine penetration in sheep skin in vitro. J Vet Pharmacol Therap. 37(2):151–160.
  • Bonamonte D, Belloni Fortina A, Neri L, Patrizi A. 2014. Fusidic acid in skin infections and infected atopic eczema. G Ital di Dermatologia e Venereol. 149(4):453–459.
  • Cojocaru V, Ranetti AE, Hinescu LG, Ionescu M, Cosmescu C, Poștoarcă AG, Cinteză LO. 2015. Formulation and evaluation of in vitro release kinetics of Na3CaDTPA decorporation agent embedded in microemulsion-based gel formulation for topical delivery. Farmacia. 63(5):656–664.
  • Coşkunmeriç N, Üstündağ Okur N, Okur ME, Ayla Ş, Yoltaş A, Karavana SY. 2021. Promising nanogels loaded with usnic acid for oral ulcer treatment: development, characterization, and in vivo evaluation in rabbits. Pharm Dev Tec. 26(4):431–443.
  • Cuggino JC, Blanco ERO, Gugliotta LM, Alvarez Igarzabal CI, Calderón M. 2019. Crossing biological barriers with nanogels to improve drug delivery performance. J Control Release. 307:221–246.
  • De Robertis S, Bonferoni MC, Elviri L, Sandri G, Caramella C, Bettini R. 2015. Advances in oral controlled drug delivery: the role of drug-polymer and interpolymer non-covalent interactions. Expert Opin Drug Deliv. 12(3):441–453.
  • Dev SK, Choudhury PK, Srivastava R, Sharma M. 2019. Antimicrobial, anti-inflammatory and wound healing activity of polyherbal formulation. Biomed Pharmacother. 111(December 2018):555–567.
  • Divya G, Panonnummal R, Gupta S, Jayakumar R, Sabitha M. 2016. Acitretin and aloe-emodin loaded chitin nanogel for the treatment of psoriasis. Eur J Pharm Biopharm. 107:97–109.
  • Dumortier G, Grossiord JL, Zuber M, Couarraze G, Chaumeil JC. 1991. Rheological study of a thermoreversible morphine gel. Drug Dev Ind Pharm. 17(9):1255–1265.
  • Ege MA, Karasulu HY, Karasulu E, Ertan G. 2001. A computer program designed for in vitro dissolution kinetics, in vitro-in vivo kinetic correlations and routine application. 4th Central European Symposium on Pharmaceutical Technology. Vienna. Scientia Pharmaceutica, Supplement 1 Band. 69:127–128.
  • El Fawal GF, Abu-Serie MM, Hassan MA, Elnouby MS. 2018. Hydroxyethyl cellulose hydrogel for wound dressing: fabrication, characterization and in vitro evaluation. Int J Biol Macromol. 111:649–659.
  • EUCAST. 2018. Routine and Extended Internal Quality Control for MIC Determination and Disk Diffusion as Recommended by EUCAST. Version 80. http://www.eucast.org
  • Fernandes Queiroz M, Melo K, Sabry D, Sassaki G, Rocha H. 2014. Does the use of chitosan contribute to oxalate kidney stone formation? Mar Drugs. 13(1):141–158.
  • Gouda R, Baishya H, Qing S. 2017. Application of mathematical models in drug release kinetics of carbidopa and levodopa ER tablets. J Dev Drugs. 06(02):1–8.
  • Goyal R, Macri LK, Kaplan HM, Kohn J. 2016. Nanoparticles and nanofibers for topical drug delivery. J Control Release. 240:77–92.
  • Gundogdu EA, Demir ES, Ekinci M, Ozgenc E, Ilem Ozdemir D, Senyigit Z, Asikoglu M. 2020. The effect of radiolabeled nanostructured lipid carrier systems containing imatinib mesylate on NIH-3T3 and CRL-1739 cells. Drug Deliv. 27(1):1695–1703.
  • Halim AS, Nor FM, Mat Saad AZ, Mohd Nasir NA, Norsa’adah B, Ujang Z. 2018. Efficacy of chitosan derivative films versus hydrocolloid dressing on superficial wounds. J Taibah Univ Med Sci. 13(6):512–520.
  • Harisa GI, Badran MM, AlQahtani SA, Alanazi FK, Attia SM. 2016. Pravastatin chitosan nanogels-loaded erythrocytes as a new delivery strategy for targeting liver cancer. Saudi Pharm J. 24(1):74–81.
  • Hoque J, Prakash RG, Paramanandham K, Shome BR, Haldar J. 2017. Biocompatible injectable hydrogel with potent wound healing and antibacterial properties. Mol Pharm. 14(4):1218–1230.
  • Huong SP, Bun H, Fourneron JD, Reynier JP, Andrieu V. 2009. Use of various models for in vitro percutaneous absorption studies of ultraviolet filters. Skin Res Technol. 15(3):253–261.
  • Jones DS, Woolfson AD, Brown AF. 1997. Textural analysis and flow rheometry of novel, bioadhesive antimicrobial oral gels. Pharm Res. 14(4):450–457.
  • Jones David S, Woolfson AD, Brown AF. 1997. Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers. Int J Pharm. 151(2):223–233.
  • Kabanov AV, Vinogradov SV. 2009. Nanogels as pharmaceutical carriers: finite networks of infinite capabilities. Angew Chem Int Ed. 48(30):5418–5429.
  • Karasulu HY, Ertan G. 2002. Different geometric shaped hydrogel theophylline tablets: statistical approach for estimating drug release, Il. Farmaco. 57(11):939–945.
  • Korsmeyer RW, Lustig SR, Peppas NA. 1986. Solute and penetrant diffusion in swellable polymers. I. Mathematical modeling. J Polym Sci B Polym Phys. 24(2):395–408.
  • Mohammed WH, Ali WK, Al-Awady MJ. 2018. Evaluation of in vitro drug release kinetics and antibacterial activity of vancomycin HCL-loaded nanogel for topical application. J Pharm Sci Res. 10(11):2747–2756.
  • Neamtu I, Rusu AG, Diaconu A, Nita LE, Chiriac AP. 2017. Basic concepts and recent advances in nanogels as carriers for medical applications. Drug Deliv. 24(1):539–557.
  • Okur ME, Karantas ID, Şenyiğit Z, Üstündağ Okur N, Siafaka PI. 2020. Recent trends on wound management: new therapeutic choices based on polymeric carriers. Asian J Pharm Sci. 15:661–684.
  • Oryan A, Alemzadeh E, Moshiri A. 2016. Biological properties and therapeutic activities of honey in wound healing: a narrative review and meta-analysis. J Tissue Viability. 25(2):98–118.
  • Padula C, Nicoli S, Pescina S, Santi P. 2019. Thin polymeric films for the topical delivery of propranolol. Colloids Surf B Biointerfaces. 174:582–586.
  • Pappa KA. 1990. The clinical development of mupirocin. J Am Acad Dermatol. 22(5 Pt 1):873–879.
  • Peppas NA. 1985. Analysis of Fickian and non-Fickian drug release from polymers. Pharm Acta Helv. 60(4):110–111.
  • Pérez-Álvarez L, Manuel Laza J, Álvarez-Bautista A. 2016. Covalently and ionically crosslinked chitosan nanogels for drug delivery. Curr Pharm Des. 22(22):3380–3398.
  • Perumal S, Ramadass SK, Madhan B. 2014. Sol-gel processed mupirocin silica microspheres loaded collagen scaffold: a synergistic bio-composite for wound healing . Eur J Pharm Sci. 52:26–33.
  • Phan HTM, Bartelt-Hunt S, Rodenhausen KB, Schubert M, Bartz JC. 2015. Investigation of Bovine Serum Albumin (BSA) attachment onto self-assembled monolayers (SAMs) using combinatorial quartz crystal microbalance with dissipation (QCM-D) and spectroscopic ellipsometry (SE). Hinderberger D, editor. PLOS One. 10(10):e0141282.
  • Rajan SS, Pandian A, Palaniappan T. 2016. Curcumin loaded in bovine serum albumin–chitosan derived nanoparticles for targeted drug delivery. Bull Mater Sci. 39(3):811–817.
  • Reddy KR, Satyanarayana SV, Reddy VJ. 2019. Development and evaluation of clobetasol-loaded solid lipid nanoparticles for topical treatment of psoriasis. Int J App Pharm. 11(5):143–150.
  • Rusu AG, Chiriac AP, Nita LE, Rosca I, Rusu D, Neamtu I. 2020. Self-assembled nanocarriers based on modified chitosan for biomedical applications: preparation and characterization. Polymers. 12(11):2593.
  • Sarfraz RM, Akram MR, Ali MR, Mahmood A, Khan MU, Ahmad H, Qaisar MN. 2019. Development and in-vitro evaluation of pH responsive polymeric nano hydrogel carrier system for gastro-protective delivery of naproxen sodium. Adv Polym Technol. 2019:1–13.
  • Şenyiğit T, Sonvico F, Barbieri S, Özer Ö, Santi P, Colombo P. 2010. Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin. J Control Release. 142(3):368–373.
  • Siafaka PI, Okur ME, Ayla Ş, Er S, Cağlar EŞ, Okur NÜ. 2019. Design and characterization of nanocarriers loaded with levofloxacin for enhanced antimicrobial activity; physicochemical properties, in vitro release, and oral acute toxicity. Brazilian J Pharm Sci. 55:1–13.
  • Siafaka PI, Üstündağ Okur N, Karantas ID, Okur ME, Gündoğdu EA. 2020. Current update on nanoplatforms as therapeutic and diagnostic tools: A review for the materials used as nanotheranostics and imaging modalities. Asian J Pharm Sci. 16(1):24–46.
  • Siafaka PI, Zisi AP, Exindari MK, Karantas ID, Bikiaris DN. 2016. Porous dressings of modified chitosan with poly(2-hydroxyethyl acrylate) for topical wound delivery of levofloxacin. Carbohydr Polym. 143:90–99.
  • Singh M, Kanoujia J, Parashar P, Arya M, Tripathi CB, Sinha VR, Saraf SK, Saraf SA. 2018. Assessment of improved buccal permeation and bioavailability of felodipine microemulsion-based cross-linked polycarbophil gel. Drug Deliv and Transl Res. 8(3):591–601.
  • Singh M, Kanoujia J, Singh P, Parashar P, Arya M, Tripathi CB, Sinha VR, Saraf SA. 2016. Development of an α-linolenic acid containing a soft nanocarrier for oral delivery-part II: buccoadhesive gel. RSC Adv. 6(103):101602–101612.
  • Singh S, Singh M, Tripathi CB, Arya M, Saraf SA. 2016. Development and evaluation of ultra-small nanostructured lipid carriers: novel topical delivery system for athlete's foot. Drug Deliv Transl Res. 6(1):38–47.
  • Sritharadol R, Nakpheng T, Wan Sia Heng P, Srichana T. 2017. Development of a topical mupirocin spray for antibacterial and wound-healing applications. Drug Dev Ind Pharm. 43(10):1715–1728.
  • Suhail M, Rosenholm JM, Minhas MU, Badshah SF, Naeem A, Khan KU, Fahad M. 2019. Nanogels as drug-delivery systems: a comprehensive overview. Ther Deliv. 10(11):697–717.
  • Talele S, Nikam P, Ghosh B, Deore C, Jaybhave A, Jadhav A. 2017. A research article on nanogel as topical promising drug delivery for diclofenac sodium. IJPER. 51(4s):S580–S587.
  • Tiwari N, Sonzogni AS, Calderón M. 2019. Can dermal delivery of therapeutics be improved using thermoresponsive nanogels? Nanomedicine. 14(22):2891–2895.
  • Üstündağ Okur N, Filippousi M, Okur ME, Ayla Ş, Çağlar EŞ, Yoltaş A, Siafaka PI. 2018. A novel approach for skin infections: controlled release topical mats of poly(lactic acid)/poly(ethylene succinate) blends containing Voriconazole. J Drug Deliv Sci Technol. 46:74–86.
  • Üstündağ Okur N, Hökenek N, Okur ME, Ayla Ş, Yoltaş A, Siafaka PI, Cevher E. 2019. An alternative approach to wound healing field; new composite films from natural polymers for mupirocin dermal delivery. Saudi Pharm J. 27(5):738–752.
  • Üstündağ Okur N, Yozgatli V, Okur ME. 2020. In vitro-in vivo evaluation of tetrahydrozoline-loaded ocular in situ gels on rabbits for allergic conjunctivitis management . Drug Dev Res. 81(6):716–727.
  • Varshosaz J, Hajian M. 2004. Characterization of drug release and diffusion mechanism through hydroxyethylmethacrylate/methacrylic acid pH-sensitive hydrogel. Drug Deliv. 11(1):53–58.
  • Wang Y, Xu S, Xiong W, Pei Y, Li B, Chen Y. 2016. Nanogels fabricated from bovine serum albumin and chitosan via self-assembly for delivery of anticancer drug. Colloids Surf B Biointerfaces. 146:107–113.
  • Ward A, Campoli-Richards DM. 1986. Mupirocin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 32(5):425–444.
  • Yadav HKS, Anwar N, Halabi A, Alsalloum GA. 2017. Nanogels as novel drug delivery systems - a review. J Pharm Pharm Res. 1(1):1–5.
  • Yang L, Xie Z, Li Z. 1999. Studies on acrylate copolymer soap-free waterborne coatings crosslinked by metal ions. J Appl Polym Sci. 74(1):91–96.
  • Yu S, Hu J, Pan X, Yao P, Jiang M. 2006. Stable and pH-sensitive nanogels prepared by self-assembly of chitosan and ovalbumin. Langmuir. 22(6):2754–2759.
  • Yurdasiper A, Ertan G, Heard CM. 2018. Enhanced delivery of naproxen to the viable epidermis from an activated poly N-isopropylacrylamide (PNIPAM) nanogel: skin penetration, modulation of COX-2 expression and rat paw oedema. Nanomedicine. 14(7):2051–2059.
  • Zhu K, Ye T, Liu J, Peng Z, Xu S, Lei J, Deng H, Li B. 2013. Nanogels fabricated by lysozyme and sodium carboxymethyl cellulose for 5-fluorouracil controlled release. Int J Pharm. 441(1–2):721–727.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.