Studies on Optimizing In Vitro Transdermal Permeation of Ondansetron Hydrochloride Using Nerodilol, Carvone, and Limonene as Penetration Enhancers

REFERENCES

• Markham A, Sorkin EM. Ondansetron: an update of its therapeutic use in chemotherapy-induced and postoperative nausea and vomiting. Drugs. 1993; 45: 931–952
   PubMed Web of Science ®Google Scholar
• Bozigian HP, Pritchard JF, Gooding AE, Pakes GE. Ondansetron absorption in adults: effect of dosage form, food, and antacids. J. Pharm. Sci. 1994; 83: 1011–1013
   PubMed Web of Science ®Google Scholar
• Hsyu PH, Pritchard JF, Bozigian HP, et al. Comparison of the pharmacokinetics of an ondansetron solution (8 mg) when administered intravenously, orally, to the colon, and to the rectum. Pharm. Res. 1994; 11: 156–159
   PubMed Web of Science ®Google Scholar
• Hussain AA, Dakkuri A. Itoh S. Nasal absorption of ondansetron in rats: an alternative route of drug delivery. Cancer Chemother. Pharmacol. 2000; 45: 432–434
   PubMed Web of Science ®Google Scholar
• Bronaugh RL, Maibach HIE. Percutaneous Absorption: Mechanisms-Methodology-Drug Delivery 2nd. Marcel Dekker; 1989, New York
   Google Scholar
• Williams AC, Barry BW. Penetration enhancers. Adv. Drug Deliv. Rev. 2004; 56: 603–618
   PubMed Web of Science ®Google Scholar
• Gao S, Singh J. In vitro percutaneous absorption enhancement of lipophilic drug tamoxifen by terpenes. J. Control. Release. 1998; 51: 193–199
   PubMed Web of Science ®Google Scholar
• Zhao K, Singh J. Mechanism of percutaneous absorption of tamoxifen by terpenes: eugenol, D-limonene and menthone. J. Control. Release. 1998; 55: 253–260
   PubMed Web of Science ®Google Scholar
• Zhao K, Singh J. In vitro percutaneous absorption of propranolol hydrochloride through porcine epidermis by terpenes/ethanol. J. Control. Release. 1999; 62: 359–366
   PubMed Web of Science ®Google Scholar
• El-Kattan AF, Asbill CS, Kim N, Michniak BB. The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities. Int. J. Pharm. 2001; 215: 229–240
   PubMed Web of Science ®Google Scholar
• Takahashi K, Rytting JH. Novel approach to improve permeation of ondansetron across shed snake skin as a model membrane. J. Pharm. Pharmacol. 2001; 53: 789–794
   PubMed Web of Science ®Google Scholar
• Dimas DA, Dallas PP, Rekkas DM. Ion pair formation as a possible mechanism for the enhancement effect of lauric acid on the transdermal permeation of ondansetron. Pharm. Dev. Technol. 2004; 9: 311–320
   PubMed Web of Science ®Google Scholar
• Dimas DA, Dallas PP, Rekkas DM. Use of an 8(1)3(2) asymmetrical factorial design for the in vitro evaluation of ondansetron permeation through human epidermis. Pharm. Dev. Technol. 2004; 9: 39–48
   PubMed Web of Science ®Google Scholar
• Gwak HS, Oh IS, Chun IK. Transdermal delivery of ondansetron hydrochloride: effects of vehicles and penetration enhancers. Drug Dev. Ind. Pharm. 2004; 30: 187–194
   PubMed Web of Science ®Google Scholar
• Gwak HS, Oh IS, Chun IK. In vitro percutaneous absorption of ondansetron hydrochloride from pressure-sensitive adhesive matrices through hairless mouse skin. Arch. Pharm. Res. 2003; 26: 644–648
   PubMed Web of Science ®Google Scholar
• Krishnaiah Y, SR, Shiva Kumar M, Raju V, Lakshmi M, Rama B. Penetration enhancing effect of ethanolic solution of menthol on transdermal permeation of ondansetron hydrochloride across rat epidermis. Drug Dev. Ind. Pharm., In press
   Google Scholar
• Keshary PR, Chien YW. Mechanism of transdermal controlled nitroglycerin administration. Part 2. Assessment of rate controlling steps. Drug Dev. Ind. Pharm. 1984; 10: 1663–1699
   Web of Science ®Google Scholar
• Michniak B, Player MR, Chapman JM, Sowell JW. Azone analogues as penetration enhancers: effect of different vehicles on hydrocortisone acetate skin permeation and retention. J. Control. Release. 1994; 32: 147–154
   Web of Science ®Google Scholar
• El-Kattan AF, Asbill CS, Michniak BB. The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in HPMC gel systems. Int. J. Pharm. 2000; 198: 179–189
   PubMed Web of Science ®Google Scholar
• Arellano A, Santoyo S, Martin C, Ygartua P. Enhancing effect of terpenes on the in vitro percutaneous absorption of diclofenac sodium. Int. J. Pharm. 1996; 130: 141–145
   Web of Science ®Google Scholar
• Williams AC, Barry BW. Terpenes and the lipid protein-partitioning theory of skin penetration enhancement. Pharm. Res. 1991; 8: 17–24
   PubMed Web of Science ®Google Scholar
• Cornwell PA, Barry BW, Stoddart CP, Bouwstra JA. Wide-angle x-ray diffraction of human stratum corneum: effects of hydration and terpene enhancer treatment. J. Pharm. Pharmacol. 1994; 46: 938–950
   PubMed Web of Science ®Google Scholar
• Berner B, Otte JH, Mazzenga GC, Steffens RJ, Ebert CD. Ethanol: water mutually enhanced transdermal therapeutic system I: Nitroglycerin solution properties and membrane transport. J. Pharm. Sci. 1989; 78: 314–318
   PubMed Web of Science ®Google Scholar
• Pershing LK, Lambert LD, Knutson K. Mechanism of ethanol-enhanced estradiol permeation across human skin in vivo. Pharm. Res. 1990; 7: 170–175
   PubMed Web of Science ®Google Scholar
• Megrab NA, Williams AC, Barry BW. Estradiol permeation across human skin, silastic and snake skin membranes: effects of ethanol/water co-solvent systems. Int. J. Pharm. 1995; 116: 101–112
   Web of Science ®Google Scholar
• Ghanem AH, Mahmoud H, Higuchi WI, Liu P, Good WR. The effects of ethanol on the transport of lipophilic and polar permeants across hairless mouse skin: Methods/validation of a novel approach. Int. J. Pharm. 1992; 78: 137–156
   Web of Science ®Google Scholar
• Hadgraft J. Passive enhancement strategies in topical and transdermal drug delivery. Int. J. Pharm. 1999; 184: 1–6
   PubMed Web of Science ®Google Scholar
• Cornwell PA, Barry BW. Sesquiterpene components of volatile oils as skin penetration enhancers for the hydrophilic permeant 5-fluorouracil. J. Pharm. Pharmacol. 1994; 46: 261–269
   PubMed Web of Science ®Google Scholar
• Ruell JA, Tsinman O, Avdeef A. Acid-base cosolvent method for determining aqueous permeability of amiodarone, itraconazole, tamoxifen, terfenadine and other very insoluble molecules. Chem. Pharm. Bull. 2004; 52: 561–565
   PubMed Web of Science ®Google Scholar
• Okabe H, Takayama K, Ogura A, Nagai T. Effect of limonene and related compounds on the percutaneous absorption of indomethacin. Drug Des. Deliv. 1989; 4: 313–321
   PubMedGoogle Scholar
• Moghimi HR, Williams AC, Barry BW. Enhancement by terpenes of 5-fluorouracil permeation through the stratum corneum: model solvent approach. J. Pharm. Pharmacol. 1998; 50: 955–964
   PubMed Web of Science ®Google Scholar
• Hori M, Satoch H, Miabach HI, Guy RH. Enhancement effect of propranolol hydrochloride and diazepam skin absorption in vitro: effect of enhancer lipophilicity. J. Pharm. Sci. 1991; 80: 32–35
   PubMed Web of Science ®Google Scholar
• Krishnaiah Y, SR, Al-Saidan SM, Chandrasekhar DV, Satyanarayana V. Bioavailability of nerodilol-based transdermal therapeutic system of nicorandil in human volunteers. J. Control. Release. 2005; 106: 111–122
   PubMed Web of Science ®Google Scholar
• Krishnaiah Y, SR, Bhaskar P, Satyanarayana V. Formulation and evaluation of limonene-based membrane-moderated transdermal therapeutic systems for nimodipine. Drug Deliv. 2004; 11: 1–9
   PubMed Web of Science ®Google Scholar