184
Views
6
CrossRef citations to date
0
Altmetric
Original Contributions

Does Emergency Medical Services Transport for Pediatric Ingestion Decrease Time to Activated Charcoal?

, MD, , MD, , MS, , ScD & , MD, MPH
Pages 295-303 | Received 17 Sep 2008, Accepted 31 Mar 2009, Published online: 13 Aug 2009

References

  • Bronstein A C, Spyker D A, Cantilena L R, Green J, Rumack B H, Heard S E. 2006 Annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS). Clin Toxicol 2007; 45: 815–917
  • Institute of Medicine. Forging a Poison Prevention and Control System. National Academies Press, Washington, DC 2004
  • Woolf A, Wieler J, Greenes D. Costs of poison-related hospitalizations at an urban teaching hospital for children. Arch Pediatr Adolesc Med 1997; 151: 719–23
  • Shannon M. Ingestion of toxic substances by children. N Engl J Med 2000; 342: 186–91
  • Chyka P A, Seger D, Krenzelok E P, Vale J A. Position paper: single-dose activated charcoal. American Academy of Clinical Toxicology, and European Association of Poison Centres and Clinical Toxicologists. Clin Toxicol 2005; 43: 61–87
  • Gaudreault P. Activated charcoal revisited. Clin Pediatr Emerg Med 2005; 6(2)76–80
  • Greene S, Harris C, Singer J. Gastrointestinal decontamination of the poisoned patient. Pediatr Emerg Care 2008; 24: 176–86
  • Bailey B. To decontaminate or not to decontaminate? The balance between potential risks and foreseeable benefits. Clin Pediatr Emerg Med 2008; 9(1)17–23
  • Isbister G K, Friberg L E, Stokes B, et al. Activated charcoal decreases the risk of QT prolongation after citalopram overdose. Ann Emerg Med 2007; 50: 593–600
  • Spiller H A, Sawyer T S. Impact of activated charcoal after acute acetaminophen overdoses treated with N-acetylcysteine. J Emerg Med 2007; 33(2)141–4
  • Wolsey B A, McKinney P E. Does transportation by ambulance decrease time to gastrointestinal decontamination after overdose?. Ann Emerg Med 2000; 35: 579–84
  • Osterhoudt K C, Alpern E R, Durbin D, Nadel F, Henretig F M. Activated charcoal administration in a pediatric emergency department. Pediatr Emerg Care 2004; 20: 493–8
  • Franklin R L, Rodgers G B. Unintentional child poisonings treated in United States hospital emergency departments: national estimates of incident cases, population-based poisoning rates, and product involvement. Pediatrics 2008; 122: 1244–51
  • Cheng T L, Wright J L, Pearson-Fields A S, Brenner R A, the DC Child/Adolescent Injury Research Network. The spectrum of intoxication and poisonings among adolescents: surveillance in an urban population. Inj Prev 2006; 12: 129–32
  • Bond G R. The role of activated charcoal and gastric emptying in gastrointestinal decontamination: a state-of-the-art review. Ann Emerg Med 2002; 39: 273–86
  • Kulig K, Bar-Or D, Cantrill S V, Rosen P, Rumack B H. Management of acutely poisoned patients without gastric emptying. Ann Emerg Med 1985; 14: 562–7
  • Pond S M, Lewis-Driver D J, Williams G M, Green A C, Stevenson N W. Gastric emptying in acute overdose: a prospective randomized controlled trial. Med J Aust 1995; 163: 345–9
  • Kornberg A D, Dolgin J. Pediatric ingestions: charcoal alone versus ipecac and charcoal. Ann Emerg Med 1991; 20: 648–51
  • LoVecchio F, Shriki J, Innes K, Bermudez J. The feasibility of administration of activated charcoal with respect to current practice guidelines in emergency department patients. J Med Toxicol 2007; 3(3)100–2
  • Reid S M, Neto G M, Clifford T J, Randhawa N, Plint A. Use of single-dose activated charcoal among Canadian pediatric emergency physicians. Pediatr Emerg Care 2006; 22(10)724–8
  • Christophersen A B, Levin D, Hoegberg L CG, Angelo H R, Kampmann J P. Activated charcoal alone or after gastric lavage: a simulated large paracetamol intoxication. Br J Clin Pharmacol 2002; 53: 312–7
  • Lapatto-Reiniluoto O, Kivisto K T, Neuvonen P J. Effect of activated charcoal alone or given after gastric lavage in reducing the absorption of diazepam, ibuprofen and citalopram. Br J Clin Pharmacol 1999; 48: 148–53
  • Lapatto-Reiniluoto O, Kivisto K T, Neuvonen P J. Gastric decontamination performed 5 minutes after the ingestion of temazepam, verapamil, and moclobemide: charcoal is superior to lavage. Br J Clin Pharmacol 2000; 49: 274–8
  • Stass H, Kubitza D, Moller J G, Delesen H. Influence of activated charcoal on the pharmacokinetics of moxifloxacin following intravenous and oral administration of a 400 mg single dose to healthy males. Br J Clin Pharmacol 2005; 59: 536–41
  • Merigian K S, Woodard M, Hedges J R, Roberts J R, Stuebing R, Rashkin M C. Prospective evaluation of gastric emptying in the self-poisoned patient. Am J Emerg Med 1990; 8: 479–83
  • Merigian K S, Blaho K E. Single-dose activated charcoal in the treatment of the self-poisoned patient: a prospective, randomized, controlled trial. Am J Ther 2002; 9: 301–8
  • Cooper G M, Le Couteur D G, Richardson D, Buckley N A. A randomized clinical trial of activated charcoal for the routine management of oral drug overdose. Q J Med 2005; 98: 655–60
  • Spiller H A, Winter M L, Klein-Schwartz W, Bangh S A. Efficacy of activated charcoal administered more than four hours after acetaminophen overdose. J Emerg Med 2006; 30(1)1–5
  • Buckley N A, Whyte I M, O'Connell D L, Dawson A. Activated charcoal reduces the need for N-acetylcysteine treatment after acetaminophen overdose. Clin Toxicol 1999; 37: 753–7
  • Karim A, Ivatts S, Dargan P, Jones A. How feasible is it to conform to the European guidelines on administration of activated charcoal within one hour of an overdose?. Emerg Med J 2001; 18: 390–2
  • Sejersten M, Sillesen M, Hansen P R, et al. Effect on treatment delay of prehospital teletransmission of 12-lead electrocardiogram to a cardiologist for immediate triage and direct referral of patients with ST-segment elevation acute myocardial infarction to primary percutaneous coronary intervention. Am J Cardiol 2008; 101: 941–6
  • Adams G L, Campbell P T, Adams J M, et al. Effectiveness of prehospital wireless transmission of electrocardiograms to a cardiologist via hand-held device for patients with acute myocardial infarction. Am J Cardiol 2006; 98: 1160–4
  • Ting H H, Krumholz H M, Bradley E H, et al. Implementation and integration of prehospital ECGs into systems of care for acute coronary syndrome: a scientific statement from the American Heart Association Interdisciplinary Council on Quality of Care and Outcomes Research, Emergency Cardiovascular Care Committee, Council on Cardiovascular Nursing, and Council on Clinical Cardiology. Circulation 2008; 118: 1066–79
  • Amsterdam E A, Miles P, Turnipseed S, Diercks D. The prehospital ECG: a simple (and effective) tool for a complex problem. Crit Pathw Cardiol 2007; 6(2)64–6
  • Curtis J P, Portnay E L, Wang Y, et al. The pre-hospital electrocardiogram and time to reperfusion in patients with acute myocardial infarction, 2000–2002: findings from the National Registry of Myocardial Infarction-4. J Am Coll Cardiol 2006; 47: 1544–52
  • Ferguson J D, Brady W J, Perron A D, et al. The prehospital 12-lead electrocardiogram: impact on management of the out-of hospital acute coronary syndrome patient. Am J Emerg Med 2003; 21: 136–42
  • Karagounis L, Ipsen S K, Jessop M R, et al. Impact of field-transmitted electrocardiography on time to in-hospital thrombolytic therapy in acute myocardial infarction. Am J Cardiol 1990; 66: 786–91
  • Venkatakrishna R, Saver J. Prehospital care of the acute stroke patient. Tech Vasc Interv Radiol 2005; 8(2)74–80
  • Lindsberg P J, Happola O, Kallela M, Valanne L, Kuisma M, Kaste M. Door to thrombolysis: ER reorganization and reduced delays to acute stroke treatment. Neurology 2006; 67: 334–6
  • American Academy of Pediatrics Committee on Injury, Violence, and Poison Prevention. Poison treatment in the home. Pediatrics 2003; 112: 1182–5
  • Crockett R, Krishel S J, Manoguerra A, Williams S R, Clark R F. Prehospital use of activated charcoal: a pilot study. J Emerg Med 1996; 14: 335–8
  • Alaspaa A O, Kuisma M J, Hoppu K, Neuvonen P J. Out-of-hospital administration of activated charcoal by emergency medical services. Ann Emerg Med 2005; 45: 207–12
  • Isbister G K, Dawson A H, Whyte I M. Feasibility of prehospital treatment with activated charcoal: who could we treat, who should we treat?. Emerg Med J 2003; 20: 375–8
  • Allison T B, Gough J E, Brown L H, Thomas S H. Potential time savings by prehospital administration of activated charcoal. Prehosp Emerg Care 1997; 1: 73–5
  • Wax P M, Cobaugh D J. Prehospital gastrointestinal decontamination of toxic ingestions: a missed opportunity. Am J Emerg Med 1998; 16: 114–6
  • Thakore S, Murphy N. The potential role of prehospital administration of activated charcoal. Emerg Med J 2002; 19: 63–5

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.