267
Views
11
CrossRef citations to date
0
Altmetric
Review

Potential of microRNA based diagnostics and therapeutics in glioma: a patent review

&
Pages 91-106 | Received 03 Jun 2020, Accepted 13 Oct 2020, Published online: 10 Dec 2020

References

  • Goodenberger ML, Jenkins RB. Genetics of adult glioma. Cancer Genet. 2012;205(12):613–621.
  • Louis DN, Perry A, Reifenberger G, et al. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Actaneuropathologica. 2016;131(6):803–820.
  • Ohgaki H, Kleihues P. The definition of primary and secondary glioblastoma. Clin Cancer Res. 2013;19(4):764–772.
  • Koshy M, Villano JL, Dolecek TA, et al. Improved survival time trends for glioblastoma using the SEER 17 population-based registries. J Neurooncol. 2012;107(1):207–212.
  • Tamimi AF, Juweid M. Epidemiology and outcome of glioblastoma. Codon Publications; 2017. p. 143–153
  • Alifieris C, Trafalis DT. Glioblastomamultiforme: pathogenesis and treatment. Pharmacol Ther. 2015;152:63–82.
  • Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987–996.
  • Hammond SM. An overview of microRNAs. Adv Drug Deliv Rev. 2015;87:3–14.
  • Saliminejad K, Khorram Khorshid HR, Soleymani Fard S, et al. An overview of microRNAs: biology, functions, therapeutics, and analysis methods. J Cell Physiol. 2019;234(5):5451–5465.
  • Yang JX, Rastetter RH, Wilhelm D. Non-coding RNAs: an introduction. In: Non-coding RNA and the reproductive system. Dordrecht: Springer; Wilhelm D, Bernard P, editors. 2016. p. 13–32
  • Simonson B, Das S. MicroRNA therapeutics: the next magic bullet? Mini Rev Med Chem. 2015;15(6):467–474.
  • Hayes J, Peruzzi PP, Lawler S. MicroRNAs in cancer: biomarkers, functions and therapy. Trends Mol Med. 2014;20(8):460–469.
  • Zhou Q, Liu J, Quan J, et al. MicroRNAs as potential biomarkers for the diagnosis of glioma: A systematic review and meta‐analysis. Cancer Sci. 2018;109(9):2651–2659
  • Wang B-C, Jie M. Role of microRNAs in malignant glioma. Chin Med J (Engl). 2015;128(9):1238.
  • Mondal I, Sharma S, Kulshreshtha R. MicroRNA therapeutics in glioblastoma: candidates and targeting strategies. In: AGO-driven non-coding RNAs. Elsevier; 2019. Mallick B, editor. p. 261–292
  • Geretto M, Pulliero A, Rosano C, et al. Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators. Am J Cancer Res. 2017;7(6):1350–1371
  • Besse A, Sana J, Fadrus P, et al. MicroRNAs involved in chemo-and radioresistance of high-grade gliomas. Tumor Biol. 2013;34(4):1969–1978.
  • Okada H, Kohanbash G, Lotze MT. MicroRNAs in immune regulation—opportunities for cancer immunotherapy. Int J Biochem Cell Biol. 2010;42(8):1256–1261.
  • Zhang Y, Wang Z, Gemeinhart RA. Progress in microRNA delivery. J Control Release. 2013;172(3):962–974.
  • Brase JC, Wuttig D, Kuner R, et al. Serum microRNAs as non-invasive biomarkers for cancer. Mol Cancer. 2010;9(1):306.
  • Ferracin M, Veronese A, Negrini M. Micromarkers: miRNAs in cancer diagnosis and prognosis. Expert Rev Mol Diagn. 2010;10(3):297–308.
  • Chin LJ, Slack FJ. A truth serum for cancer—microRNAs have major potential as cancer biomarkers. Cell Res. 2008;18(10):983–984.
  • Zhang J, Zhao H, Gao Y, et al. Secretory miRNAs as novel cancer biomarkers. BiochimicaetBiophysicaActa (Bba)-rev Cancer. 2012;1826(1):32–43.
  • Heneghan HM, Miller N, Kerin MJ. MiRNAs as biomarkers and therapeutic targets in cancer. Curr Opin Pharmacol. 2010;10(5):543–550.
  • Chakraborty C, Sharma AR, Sharma G, et al. Therapeutic miRNA and siRNA: moving from bench to clinic as next generation medicine. Mol Ther Nucleic Acids. 2017;8:132–143.
  • Zou C, Li D, Lai L, et al. Application of miRNA-29a compound as brain glioma marker. 2011. (CN102031308A)
  • Zou C, Li D, Lai L, et al. Application of miRNA-34c compound as brain glioma marker. 2011. (CN102031309A)
  • Zou C, Li D, Dong D, et al. Application of micro ribonucleic acid (miRNA)-219 compound as marker of brain glioma. 2011. (CN102041316A)
  • Li G, Minghua W, Tang H, Wu M, et al. Application of miR-182 as glioma generating molecular marker and detective reagent kit thereof. 2012. (CN101792793B)
  • Min D, Li G, Liu X, et al. Application and detection kit of human miR-183/96/182 cluster. 2013. (CN102424843B)
  • Keller A, Markus B. Complex sets of miRNAs as non-invasive biomarkers for glioblastoma. 2013. (WO2012089753)
  • Somasundaram K, Aliga S, Rao M, et al. MicroRNAs (miRNA) as biomarkers for diagnosing different grades of gliomas and pathways of glioma progression. 2014. (US8637241B2).
  • Chunping J, Junhua W. MicroRNA molecular marker for diagnosing glioma and application of microRNA molecular marker. 2015. (CN104313171A)
  • Chiou S-H, Chiou G-Y. MicroRNA as a cancer progression predictor and its use for treating cancer. 2015. (US9107934B2).
  • Shi Y, Lang M-F, Zhao C. Differentially expressed microRNA molecules for the treatment and diagnosis of cancer. 2016. (US9315809B2).
  • Kolesnikov N, Titov S, Akhmerova L, et al. Method for differential diagnosis of gliomas of human brain. 2016. (RU2583871C1)
  • Berger F, Issartel J, Atifi-Borel M, et al. Use of miRNAs as biomarkers for diagnosing gliomas. 2017. (EP2510122B1)
  • Zollo M. Use of microRNA-199b-5p in medical and diagnostic field. 2017. (EP2411515B1).
  • Krichevsky AM, Teplyuk N, Kesari S, et al. Diagnosing and monitoring CNS malignancies using microRNA. 2018. (US10100367B2)
  • Zaraisky IM, Sazanov AA, Seliverstov RY, et al. Method of diagnostics and monitoring of course of cerebral gliomas. 2018. (RU2656182C1)
  • Kim G-H, Kim G, Kim S, et al. Composition for diagnosing recurring glioblastoma multiforme and method for diagnosing same. 2019. (US10266898B2)
  • Gang L, Qian M, Wang S, et al. Application of miR-1246 and/or TERF2IP in diagnosis and treatment of glioma. 2019. (CN109762903A)
  • Gang L, Guo Q, Han L, et al. Cerebrospinal fluid exosome miRNA marker related to glioma and application of cerebrospinal fluid exosome miRNA marker. 2019. (CN110129445A)
  • Rui Y, Zhongzheng S, Gang L, et al. Molecular marker for diagnosing or treating glioma and applications thereof. 2019. (CN109609653B)
  • Somasundaram K, Srinivasan S, Patric IRP, et al. Method for predicting survival of glioblastoma patient using a ten-miRNA signature.2012. (WO2012114189A1)
  • Shaw L, Alder J, Tumilson C. Detection of brain cancer. 2019. (EP3019627B1).
  • Oldenhuis CNAM, Oosting SF, Gietema JA, et al. Prognostic versus predictive value of biomarkers in oncology. Eur J Cancer. 2008;44(7):946–953.
  • Tao J, Wei Z. Molecular marker associated with temozolomide for treating glioblastoma. 2013. (CN102329860B).
  • Zihuang L, Chang Z, Lue Z. Application of microRNA in exosome to evaluation of radiation therapy effect of brain glioma. 2019. (CN110616262A)
  • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. cell. 2011;144(5):646–674.
  • Zhang Y, Chao T, Li R, et al. MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. J Mol Med. 2009;87(1):43–51.
  • Hui W, Yuntao L, Lun L, et al. MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1. PloS One. 2013;8(1):e54932.
  • Godlewski J, Bronisz A, Nowicki MO, et al. microRNA-451: A conditional switch controlling glioma cell proliferation and migration. Cell Cycle. 2010;9(14):2814–2820.
  • Ling N, GU J, LEI Z, et al. microRNA-155 regulates cell proliferation and invasion by targeting FOXO3a in glioma. Oncol Rep. 2013;30(5):2111–2118.
  • Mourad PD, Farrell L, Stamps LD, et al. Why are systemic glioblastoma metastases rare? Systemic and cerebral growth of mouse glioblastoma. Surg Neurol. 2005;63(6):511–519.
  • Matzuk MM, Creighton C, Yu Z, et al. MicroRNA miRNA-31 as a therapeutic approach for the treatment of cancer. 2011. (WO2011047147A1)
  • Gaur AB, Israel MA. MicroRNA-21 antagonists and its target PDCD4 for use in the treatment of a glioma. 2012. (US8106028B2).
  • Gaur AB, Israel MA. MicroRNA-10 antagonists and MicroRNA-10 targets for use in the treatment of a glioma. 2014. (US8778903B2).
  • Chunfa D, Chao S, Chen W, et al. miRNA simulant inhibiting gene expression and proliferation of human cell division cyclin 42 gene as well as expression vector and application thereof. 2014. (CN103898117A)
  • Yanchun D, Li W. miRNA (ribonucleic acid) with neuroglioma inhibition function, vector built by same and application. 2014. (CN104232647A)
  • Chunping J, Junhua W. Application of microRNA-29a in preparation of drugs for treating neuroglioma. 2015. (CN104399088A)
  • Peruzzi F, Jeansonne D. Use of an miRNA to reduce proliferation of a cancer cell. 2019. (US10308939B2)
  • Shiro O, Okun O, Daisuke Y et al. microRNA with glioma formation inhibitory action. 2017. (JP6073775B2)
  • Kan D, Nan D, Jie L et al. Human miR-133a antisense nucleic acid and application thereof. 2012. (CN102080086B).
  • Kan D, Nan D, Jie L et al. Human miR-193b antisense nucleotide and application thereof. 2013. (CN102080085B).
  • Kan D, Nan D, Jie L et al. Human miR-149 antisense nucleotide and application thereof. 2013. (CN102080083B).
  • Kan D, Nan D, Jie L et al. Human miR-1826 antisense nucleic acid and application thereof. 2013. (CN102382825B).
  • Kan D, Nan D, Jie L et al. HumanmiR-485-5p antisense nucleic acid and application thereof. 2013. (CN102031256B).
  • Kan D, Chunxiao D, Jie L et al. Human miR-1825 antisense nucleic acid and application thereof. 2013. (CN102140466B).
  • Kan D, Chunxiao D, Jie L et al. Human miR (microRNA)-1233 antisense nucleic acid and application thereof. 2013. (CN102140469B).
  • Kan D, Nan D, Jie L et al. Human miR-515-5p antisense oligodeoxynucleotide and applications thereof. 2013. (CN102382823B).
  • Kan D, Chunxiao D, Jie L et al. Human miR-365 antisense nucleic acid and application thereof. 2013. (CN102140467B).
  • Kan D, Nan D, Jie L et al. Human miR-129* antisense nucleic acid and applications thereof. 2013. (CN102080082B).
  • Kan D, Nan D, Jie L et al. Human miR-125a-5p antisense nucleotide and application thereof. 2013. (CN102080084B).
  • Kan D, Nan D, Jie L et al. Antisense nucleic acid of human miR-223 and applications of antisense nucleic acid. 2013. (CN102031255B).
  • Kan D, Nan D, Jie L et al. Human miR-1260 antisense nucleic acid and application thereof. 2013. (CN102140462B).
  • Kan D, Chunxiao D, Jie L et al. Human miR-1249 antisense nucleic acid and application thereof. 2013. (CN102140465B).
  • Kan D, Chunxiao D, Jie L et al. Human miR-1236 antisense ribonucleic acid and application thereof. 2013. (CN102140470B).
  • Kan D, Chunxiao D, Jie L et al. Human miR-1238 antisense nucleic acid and applications thereof. 2013. (CN102140464B).
  • Kan D, Nan D, Jie L et al. Human miR-150 antisense nucleic acid and application thereof. 2014. (CN102031254B).
  • Kan D, Jie L, Xiaokun S et al. Antisense oligodeoxyncleotide of human miR-484 and application thereof. 2015. (CN102643807B).
  • Kan D, Jie L, Xiaokun S et al. Antisense oligonucleotide for human miR-431 and application thereof. 2015. (CN102643814B).
  • Jie L, Kan D, Zhang P et al. Antisense human miR-504 and its application. 2015. (CN102643813B)
  • Jie L, Kan D, Zhang P et al. Antisense human miR-1229 and its application. 2015. (CN102643811B)
  • Jie L, Kan D, Zhang P et al. Antisense human miR-299-5p and its application. 2015. (CN102643810B)
  • Jie L, Kan D, Zhang P et al. Antisense human miR-1539 and its application. 2016. (CN102643808B)
  • Jie L, Kan D, Zhang P et al. Antisense human miR-1274b and its application. 2016. (CN102643809B)
  • Jie L, Kan D, Zhang P et al. Antisense human miR-1227 and its application. 2016. (CN102643812B)
  • Kan D, Peizuo Z, Jie L et al. Antisense human miR-1913 and its application. 2016. (CN102643806B).
  • Kan D, Peizuo Z, Jie L, et al. Human miR-185* antisense nucleic acid and application thereof. 2011. (CN102140468A)
  • Kan D, Peizuo Z, Jie L, et al. Human miR (microRNA)-1296 antisense nucleic acid and application thereof. 2011. (CN102140463A)
  • Kan D, Peizuo Z, Jie L et al. Human miR-145 antisense nucleic acid and application thereof. 2012. (CN102382824A)
  • Kan D, Peizuo Z, Jie L et al. Human miR-328 antisense nucleic acid and application thereof. 2012. (CN102533755A)
  • Kan D, Peizuo Z, Jie L et al. Human miR-486-5p antisense nucleic acid and application thereof. 2013. (CN102041256B)
  • Shi Z, Chunsheng K, Junxia Z et al. Small molecule inhibitors of miR-21 and Application. 2016. (CN103044338B).
  • Leedman P, Giles K, Webster RJ. Procedure for modulating expression of epidermal growth factor receptor (EGFR) concerning miRNA. 2015. (DK2061482T3).
  • Krichevsky AM, El-Fatimy R, Uhlmann EJ. Genome Editing for Treating Glioblastoma. 2017. (WO2017123910A1)
  • Allerson CR MicroRNA compounds and methods for modulating miR-10b activity. 2020. (WO2020102142A1).
  • Wang S. Application of anti-sense miRNA (Ribonucleic Acid)-210 to preparation of anti-cancer drug. 2012. (CN102475892A).
  • Chunping J, Junhua W. Application of microRNA-29a in preparing medicine for inhibiting glioma invasion and metastasis. 2015. (CN104306997A)
  • Xing G, Gang L, Hong L, et al. Application of microRNA-29a-3p as glioma blood vessel mimesis control target spot. 2020. (CN110946873A)
  • Clarke MF, Hass AT. Cancer stem cells. Rev Cell Biol Mol Med. RA Meyers, editor. 2006. p. 221–41
  • Reya T, Morrison SJ, Clarke MF, et al. Stem cells, cancer, and cancer stem cells. Nature. 2001;414(6859):105–111.
  • Li L, Neaves WB. Normal stem cells and cancer stem cells: the niche matters. Cancer Res. 2006;66(9):4553–4557.
  • Wang B, Bian X, Wang Z et al. Application of miRNA-106a and miRNA-106a inhibitor in preparing glioblastoma stem cell invasion regulator. 2012. (CN102321585B).
  • Chiou S-H, Hsu H-S, Cherng J-Y. Method for inhibiting cancer stem cell like properties and chemoradioresistant properties of cancer or tumor cells with microRNA145. 2014. (US8846633B2).
  • Ting S, Wei Y. Application of miRNA-153 in preparation of glioma stem cell radiosensitizing agent. 2015. (CN104840974B).
  • Sampath P. Targeting glioma stem cells by sequence-specific functional inhibition of pro-survival oncomiR-138. 2017. (EP2654801B1).
  • Jing S, Mingfei L. Application of small molecule RNA hsa-miR-874 in the tumor medicament for the treatment of glioblastoma. 2018. (CN105412140B).
  • Kim I-A, Cho B-J, Choi E-J, et al. Modulation of radiation response using microRNA. 2015. (US8980863B2).
  • Park JB, Lee SH, Kwak HJ, et al. Composition containing microRNA-21 inhibitor for enhancing radiation sensitivity. 2014. (US8883751B2)
  • Chaudhary B, Elkord E. Regulatory T cells in the tumor microenvironment and cancer progression: role and therapeutic targeting. Vaccines (Basel). 2016;4(3):28.
  • Carbone JE, Ohm DP. Immune dysfunction in cancer patients. Oncol (Huntingt). 2002;16(1 suppl 1):11–18.
  • Sidler D, Renzulli P, Schnoz C, et al. Colon cancer cells produce immunoregulatory glucocorticoids. Oncoimmunology. 2012;1(4):529–530.
  • Tindle RW. Immune evasion in human papillomavirus-associated cervical cancer. Nat Rev Cancer. 2002;2(1):59–64.
  • Holmstrøm K, Pedersen AW, Claesson MH, et al. Identification of a microRNA signature in dendritic cell vaccines for cancer immunotherapy. Hum Immunol. 2010;71(1):67–73.
  • Romano G, Kwong LN. Diagnostic and therapeutic applications of miRNA-based strategies to cancer immunotherapy. Cancer Metast Rev. 2018;37(1):45–53.
  • Heimberger A, Wei J. miRNA for treating cancer and for use with adoptive immunotherapies. 2017. (US9675633B2).
  • Okada H, Kohanbash G, Sasaki K. Th1-associated microRNAs and their use for tumor immunotherapy. 2013. (US8486911B2).
  • Weiming F, Jinfang Z. MicroRNA for preparing a medicament to reduce the use of gliomas to TRAIL resistance. 2016. (CN103961720B).
  • Shea A, Harish V, Afzal Z, et al. MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics. Cancer Med. 2016;5(8):1917–1946.
  • Chen Y, Gao D-Y, Huang L. In vivo delivery of miRNAs for cancer therapy: challenges and strategies. Adv Drug Deliv Rev. 2015;81:128–141.
  • Katakowski ME, Buller BAL, Chopp M. Methods, systems, and compositions for cell-derived/vesicle-based microRNA delivery. 2017. (US9555060B2).
  • Rosin-Arbesfeld R, Sklan E, Zilberberg A, et al. miR-21 promoter driven targeted cancer therapy. 2013. (US8492133B2).
  • Chunxiao W, Wang Shu, et al. Nucleic acid molecule and method of targeting gene expression to gliomas. 2011. (CN102099472A)
  • Guocai G, Jia L, Leina M, et al. Adenovirus capable of expressing anti-cancer gene efficiently, regulated by miRNA and capable of specifically proliferating in glioma cells and application thereof. 2014. (CN103667347A)

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.