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Research Article

Advances in the Biology of JC Virus and Induction of Progressive Multifocal Leukoencephalopathy

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Pages 236-246 | Published online: 10 Jul 2009

References

  • Agostini HT, Jobes DV, Stoner GL (2001). Molecular evo-lution and epidemiology of JC virus. In: Human poly-omaviruses: molecular and clinical perspectives. Khalili K, Stoner GL (eds). New York: John Wiley and Sons, pp 491–526.
  • Aksamit AJ (2001). Treatment of non-AIDS progressive multifocal leukoencephalopathy with cytosine arabi-noside. NeuroVirol 7: 386–390.
  • Aksamit AJ, Major EO, et al (1987). Diagnosis of progres-sive multifocal leukoencephalopathy by brain biopsy with biotin labeled DNA:DNA in situ hybridization. J Neuropathol Exp Neurol 46: 556–566.
  • Amemiya K, Traub R, et al (1989). Interaction of a nuclear factor-1-like protein with the regulatory region of the human polyomavirus JC virus. J Biol Chem 264: 7025–7032.
  • Amemiya K, Traub R, et al (1992). Adjacent nuclear factor-1 and activator protein binding sites in the en-hancer of the neurotropic JC virus. A common charac-teristic of many brain-specific genes. J Biol Chem 267: 14204–14211.
  • Andrei G, Snoeck R, et al (1997). Activities of various com-pounds against murine and primate polyomaviruses. Antimicrobial Agents Chemother 41: 587–593.
  • Antinori A, A=assari A, et al (2001). Epidemiology and prognosis of AIDS-associated progressive multifo-cal leukoencephalopathy in the HAART era. J NeuroVi-rol 7: 323–328.
  • Ariza A, von Uexkull-Guldeband C, et al (1996). Accumu-lation of wild-type p53 protein in progressive multifo-cal leukoencephalopathy: a flow of cytometry and DNA sequencing study. J Neuropathol Exp Neurol 55: 144–149.
  • Astrom KE, Mancall EL, et al (1958). Progressive multifo-cal leukoencephalopathy. Brain 81: 93–127.
  • Atwood WJ (2001). A combination of low-dose chlorpro-mazine and neutralizing antibodies inhibits the spread of JC virus (JCV) in a tissue culture model: implica-tions for prophylactic and therapeutic treatment of pro-gressive multifocal leukencephalopathy. J NeuroVirol 7: 307–310.
  • Berger JR, Concha M (1995). Progressive multifocal leukoencephalopathy: the evolution of a disease once considered rare. J NeuroVirol 1: 5–18.
  • Bofill-Mas S, Formiga-Cruz M, et al (2001). Potential trans-mission of human polyomaviruses through the gastroin-testinal tract after exposure to virions or viral DNA. J Virol 75: 10290–10299.
  • Caldarelli-Stefano R, Boldorini R, et al (2000). JC virus in human glial-derived tumors. Hum Pathol 31: 394–395.
  • Chang D, Fung CY, et al (1997). Self-assembly of the JC virus major capsid protein, VP1, expressed in insect cells. J Gen Virol 78 (Pt 6): 1435–1439.
  • Chen NN, Khalili K (1995). Transcriptional regulation of human JC polyomavirus promoters by cellular proteins YB-1 and Pur alpha in glial cells. J Virol 69: 5843–5848.
  • Chowdhury M, Kundu M, et al (1993). GA/GC-rich sequence confers Tat responsiveness to human neu-rotropic virus promoter, JCVL, in cells derived from cen-tral nervous system. Oncogene 8: 887–892.
  • Cinque P, Koralnik IJ, et al (2003). The evolving face of HIV-related progressive multifocal leukoencephalopa-thy: Defining a consensus terminology. J NeuroVirol 9(s1): (In press).
  • Cinque P, Scarpellini P, et al (1997). Diagnosis of central nervous system complications in HIV-infected patients: cerebrospinal fluid analysis by the polymerase chain re-action. AIDS 11: 1–17.
  • Clifford DB, Yiannoutsos C, et al (1999). HAART im-proves prognosis in HIV-associated progressive multi-focal leukoencephalopathy. Neurology 52: 623–625.
  • Daniel AM, Swenson JJ, et al (1996). Sequences within the early and late promoters of archetype JC virus restrict viral DNA replication and infectivity. Virology 216: 90–101.
  • Darbinyan A, Darbinian N, et al (2002). Evidence for dys-regulation of cell cycle by human polyomavirus, JCV, late auxiliary protein. Oncogene 21: 5574–5581.
  • De Luca A, Fantoni M, et al (1999). Response to cido-fovir after failure of antiretroviral therapy alone in AIDS-associated progressive multifocal leukoencephalopathy. Neurology 52: 891–892.
  • De Luca A, Giancola ML, et al (2001). Potent anti-retroviral therapy with or without cidofovir for AIDS-associated progressive multifocal leukoencephalopathy: extended follow-up of an observational study. J NeuroVirol 7: 364–368.
  • De Luca A, Giancola ML, et al (2000a). Cidofovir added to HAART improves virological and clinical outcome in AIDS-associated progressive multifocal leukoen-cephalopathy. AIDS 14: F117–F121.
  • De Luca A, Giancola ML, et al (2000b). The effect of potent antiretroviral therapy and JC virus load in cerebrospinal fluid on clinical outcome of patients with AIDS-associated progressive multifocal leukoen-cephalopathy. j Infect Dis 182: 1077–1083.
  • Del Valle L, Gordon J, et al (2001). Detection of JC virus DNA sequences and expression of the viral regulatory protein T-antigen in tumors of the central nervous sys-tem. Cancer Res 61: 4287–4293.
  • Dorries K, Vogel E, et al (1994). Infection of human poly-omaviruses JC and BK in peripheral blood leukocytes from immunocompetent individuals. Virology 198: 59–70.
  • Frisque RJ (2001). Structure and function of JC virus T' proteins. J NeuroVirol 7: 293–297.
  • Frisque RJ, Bream GL, et al (1984). Human polyomavirus JC virus genome. J Virol 51: 458–469.
  • Frisque RJ, White FA (1992). The molecular biology of JC virus, causative agent of progressive multifocal leukoen-cephalopathy. In: Molecular neurovirology, Roos R (ed.). pp. 25–158, Humana Press, New Jersey.
  • Garcia De Viedma D, Diaz Infantes M, et al (2002). JC virus load in progressive multifocal leukoencephalopa-thy: analysis of the correlation between the viral bur-den in cerebrospinal fluid, patient survival, and the volume of neurological lesions. Clin Infect Dis 34: 1568–1575.
  • Gasnault J, Kousignian P, et al (2001). Cidofovir in AIDS-associated progressive multifocal leukoencephalopa-thy: a monocenter observational study with clinical and JC virus load monitoring. I NeuroVirol 7: 375–381.
  • Gasnault J, Taoufik Y, eta] (1999). Prolonged survival with-out neurological improvement in patients with AIDS-related progressive multifocal leukoencephalopathy on potent combined antiretroviral therapy. J NeuroVirol 5: 421–429.
  • Geschwind MD, Skolasky RI, et al (2001). The relative con-tributions of HAART and alpha-interferon for therapy of progressive multifocal leukoencephalopathy in AIDS. J NeuroVirol 7: 353–357.
  • Giudici B, Vaz B, et al (2000). Highly active antiretroviral therapy and progressive multifocal leukoencephalopa-thy: effects on cerebrospinal fluid markers of JC virus replication and immune response. Clin Infect Dis 30: 95–99.
  • Goldmann C, Petry H, et al (1999). Molecular cloning and expression of major structural protein VP1 of the human polyomavirus JC virus: formation of virus-like particles useful for immunological and therapeutic studies. J Virol 73: 4465–4469.
  • Goldmann C, Stolte N, et al (2000). Packaging of small molecules into VP1-virus-like particles of the human polyomavirus JC virus. J Virol Methods 90: 85–90.
  • Greenlee JE (1989). In: Progressive multifocal leukoen-cephalopathy, Remington LS, Schwartz MN (eds.). p. 140, Blackwell Scientific, Boston.
  • Greenlee JE, Keeney PM (1986). I=unoenzymatic la-belling of JC papovavirus T antigen in brains of patients with progressive multifocal leukoencephalopathy. Acta Neuropathol (Berl) 71: 150–153.
  • Hall CD, Dafni U, et al (1998). Failure of cytarabine in progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. AIDS Clinical Trials Group 243 Team. NEng/JMed 338: 1345–1351.
  • Hamilton RS, Gravell M, et al (2000). Comparison of anti-body titers determined by hemagglutination inhibition and enzyme immunoassay for JC virus and BK virus. J Clin Microbic)] 38: 105–109.
  • Henson J, Saffer J, et al (1992). The transcription factor Sp1 binds to the JC virus promoter and is selectively expressed in glial cells in human brain. Ann Neurol 32: 72–77.
  • Hou J, Major EO (1998). The efficacy of nucleoside analogs against JC virus multiplication in a persistently in-fected human fetal brain cell line. J NeuroVirol 4: 451–456.
  • Houff SA, Major EO, et al (1988). Involvement of JC virus-infected mononuclear cells from the bone mar-row and spleen in the pathogenesis of progressive mul-tifocal leukoencephalopathy. N Engl J Med 318: 301–305.
  • Houston S, Roberts N, et al (2001). Failure of cidofovir ther-apy in progressive multifocal leukoencephalopathy un-related to human immunodeficiency virus. Clin Infect Dis 32: 150–152.
  • Huang SS, Skolasky RL, et al (1998). Survival prolonga-tion in HIV-associated progressive multifocal leukoen-cephalopathy treated with alpha-interferon: an observa-tional study. J NeuroVirol 4: 324–332.
  • Jensen PN, Major EO (2001). A classification scheme for hu-man polyomavirus JCV variants based on the nucleotide sequence of the noncoding regulatory region. J NeuroVi-rol 7: 280–287.
  • Kepes JJ, Chou SM, et al (1975). Progressive multifocal leukoencephalopathy with 10-year survival in a patient with nontropical sprue. Report of a case with unusual light and electron microscopic features. Neurology 25: 1006–1012.
  • Kerr D, Chang CF, et al (1994). Transcription of a human neurotropic virus promoter in glial cells: effect of YB-1 on expression of the JC virus late gene. J Virol 68: 7637–7643.
  • Khalili K, Krynska B, et al (1999). Medulloblastomas and the human neurotropic polyomavirus JC virus. Lancet 353: 1152–1153.
  • Komagome R, Sawa H, et al (2002). Oligosaccharides as receptors for JC Virus. J Virol 76: 12992–13000.
  • Koralnik IJ, Du Pasquier RA, et al (2002). Association of prolonged survival in HLA-A2+ progressive multifo-cal leukoencephalopathy patients with a CTL response specific for a commonly recognized JC virus epitope. J Immuno1168: 499–504.
  • Koralnik IJ, Du Pasquier RA, et al (2001). JC virus-specific cytotoxic T lymphocytes in individuals with progres-sive multifocal leukoencephalopathy. J Virol 75: 3483–3487.
  • Kunitake T, Kitamura T, et al (1995). Parent-to-child trans-mission is relatively common in the spread of the hu-man polyomavirus JC virus. J Clin Microbic)] 33: 1448–1451.
  • Levy RM, Ward S, et al (1997). Alternative delivery sys-tems for antiviral nucleosides and antisense oligonu-cleotides to the brain. J NeuroVirol 3\(Suppl 1): S74–575.
  • Liu CK, Wei G, et al (1998). Infection of glial cells by the human polyomavirus JC is mediated by an N-linked gly-coprotein containing terminal alpha(2–6)-linked sialic acids. J Virol 72: 4643–4649.
  • London WT, Houff SA, et al (1978). Brain tumors in owl monkeys inoculated with a human polyomavirus (JC virus). Science 201: 1246–1249.
  • Ma DD, Doan TL (1994). Antisense oligonucleotide thera-pies: are they the "magic bullets"? Ann Intern Med 120: 161–163.
  • Major EO (2001). Human Polyomavirus. In: Fields Virol-ogy, fourth edition, Knipe DM, Howley PM et al (eds.). pp. 2175–2196, Lippincott, Williams and Wilkins, New York.
  • Major EO, Amemiya K, et al (1990). Glial cells of the human developing brain and B cells of the immune system share a common DNA binding factor for recognition of the regulatory sequences of the human polyomavirus, JCV. J Neurosci Res 27: 461–471.
  • Major EO, Amemiya K, et al (1992). Pathogenesis and molecular biology of progressive multifocal leukoen-cephalopathy, the JC virus-induced demyelinating dis-ease of the human brain. Clin Microbiol Rev 5: 49–73.
  • Mamidi A, DeSimone JA, et al (2002). Central nervous sys-tem infections in individuals with HIV-1 infection. J NeuroVirol 8: 158–167.
  • Marra CM, Rajicic N, et al (2002). A pilot study of cido-fovir for progressive multifocal leukoencephalopathy in AIDS. AIDS 16: 1791–1797.
  • McGuire D, Barhite S, et al (1995). JC virus DNA in cerebrospinal fluid of human immunodeficiency virus-infected patients: predictive value for progressive mul-tifocal leukoencephalopathy. Ann Neurol 37: 395–399.
  • Miralles P, Berenguer J, et al (1998). Treatment of AIDS-associated progressive multifocal leukoencephalopathy with highly active antiretroviral therapy. AIDS 12: 2467–2472.
  • Miralles P, Berenguer J, et al (2001). Inflammatory reac-tions in progressive multifocal leukoencephalopathy af-ter highly active antiretroviral therapy. AIDS 15: 1900–1902.
  • Monaco MC, Jensen PN, et al (1998). Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection. J Virol 72: 9918–9923.
  • Monaco MC, Sabath BF, et al (2001). JC virus multiplication in human hematopoietic progenitor cells requires the NF-1 class D transcription factor. J Virol 75: 9687–9695.
  • Okada Y, Endo S, et al (2001). Distribution and function of JCV agnoprotein. J NeuroVirol 7: 302–306.
  • Okada Y, Sawa H, et al (2002). Expression of JC virus agno-protein in progressive multifocal leukoencephalopathy brain. Acta Neuropathol (Bed) 104: 130–136.
  • Padgett BL, Walker DL, et al (1971). Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1: 1257–1260.
  • Pfister LA, Letvin NL, et al (2001). JC virus regulatory region tandem repeats in plasma and central nervous system isolates correlate with poor clinical outcome in patients with progressive multifocal leukoencephalopathy. J Vi-rol 75: 5672–5676.
  • Pho MT, Ashok A, et al (2000). JC virus enters human glial cells by clathrin-dependent receptor-mediated endocy-tosis. J Virol 74: 2288–2292.
  • Portilla J, Boix V, et al (2000). Progressive multifocal leukoencephalopathy treated with cidofovir in HIV-infected patients receiving highly active anti-retroviral therapy. J Infect 41: 182–184.
  • Power C, Gladden JG, et al (2000). AIDS- and non-AIDS-related PML association with distinct p53 polymor-phism. Neurology 54: 743–746.
  • Raj GV, Khalili K (1994). Identification and characterization of a novel GGA/C-binding protein, GBP-i, that is rapidly inducible by cytokines. Mol Cell Biol 14: 7770–7781.
  • Raj GV, Khalili K (1995). Transcriptional regulation: lessons from the human neurotropic polyomavirus, JCV. Virol-ogy 213: 283–291.
  • Ranganathan PN, Khalili K (1993). The transcriptional en-hancer element, kappa B, regulates promoter activity of the human neurotropic virus, JCV, in cells derived from the CNS. Nucleic Acids Res 21: 1959–1964.
  • Razonable RR, Aksamit AJ, et al (2001). Cidofovir treat-ment of progressive multifocal leukoencephalopathy in a patient receiving highly active antiretroviral therapy. Mayo Clin Proc 76: 1171–1175.
  • Ricciardiello L, Laghi L, et al (2000). JC virus DNA se-quences are frequently present in the human upper and lower gastrointestinal tract. Gastroenterology 119: 1228–1235.
  • Richardson EP Jr (1961). Progressive multifocal leukoen-cephalopathy. N Eng J Med 265: 815–823.
  • Richardson EP, Webester HD (1983). Progressive multifocal leukoencephalopathy: Its pathologic features. In: Polyo-maviruses and human neurological diseases, Sever JL, Madden DL (eds.). p. 191, Alan R Liss, New York.
  • Richardson-Burns SM, et al (2002). Progressive multi-focal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of pa-tients with and without AIDS. Arch Neurol 59: 1930–1936.
  • Safak M, Barrucco R, et al (2001). Interaction of JC virus agno protein with T antigen modulates transcription and replication of the viral genome in glial cells. J Virol 75: 1476–1486.
  • Schneider EM, Dorries K (1993). High frequency of poly-omavirus infection in lymphoid cell preparations af-ter allogeneic bone marrow transplantation. Transplant Proc 25: 1271–1273.
  • Staib C, Pesch J, et al (1996). p53 inhibits JC virus DNA replication in vivo and interacts with JC virus large T-antigen. Virology 219: 237–246.
  • Sumner C, Shinohara T, et al (1996). Expression of multiple classes of the nuclear factor-1 family in the developing human brain: differential expression of two classes of NF-1 genes. J NeuroVirol 2: 87–100.
  • Suzuki M, Zheng HY, et al (2002). Asian genotypes of JC Virus in Japanese-Americans suggest familial transmis-sion. J Virol 76: 10074–10078.
  • Tantisiriwat W, Tebas P, et al (1999). Progressive multifocal leukoencephalopathy in patients with AIDS receiving highly active antiretroviral therapy. Clin Infect Dis 28: 1152–1154.
  • Taoufik Y, Delfraissy JF, et al (2000). Highly active antiretro-viral therapy does not improve survival of patients with high JC virus load in the cerebrospinal fluid at progres-sive multifocal leukoencephalopathy diagnosis. AIDS 14: 758–759.
  • Tomatore C, Berger JR, et al (1992). Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy. Ann Neurol 31: 454–462.
  • Trowbridge PW, Frisque RJ (1995). Identification of three new JC virus proteins generated by alternative splicing of the early viral mRNA. J NeuroVirol 1: 195–206.
  • Walker DL, Padgett BL, et al (1973). Human papovavirus (JC): induction of brain tumors in hamsters. Science 181: 674–676.
  • Weber T, Major EO (1997a). Progressive multifocal leukoen-cephalopathy: molecular biology, pathogenesis and clin-ical impact. Intervirology 40: 98–111.
  • Weber T, Trebst C, et al (1997b). Analysis of the systemic and intrathecal humoral immune response in progres-sive multifocal leukoencephalopathy. J Infect Dis 176: 250–254.
  • Weber T, Turner RW, et al (1994). Progressive multifocal leukoencephalopathy diagnosed by amplification of JC virus-specific DNA from cerebrospinal fluid. AIDS 8: 49–57.
  • Wegner M, Drolet DW, et al (1993). Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoen-cephalopathy. Proc Nati Acad Sci USA 90: 4743–4747.
  • Willoughby E, Price RW, et al (1980). Progressive multifo-cal leukoencephalopathy (PML): in vitro cell-mediated immune responses to mitogens and JC virus. Neurology 30: 256–262.
  • Yang B, Prayson RA (2000). Expression of Bax, Bc1-2, and P53 in progressive multifocal leukoencephalopathy. Mod Pathol 13: 1115–1120.
  • Zambrano A, Kalantari M, et al (2002). Detection of human polyomaviruses and papillomaviruses in prostatic tis-sue reveals the prostate as a habitat for multiple viral infections. Prostate 53: 263–276.
  • ZuRhein GM (1969). Association of papova-virions with a human demyelinating disease, progressive multi-focal leukoencephalopathy. Prog Med Virol 11:185–247.
  • ZuRhein GM, Chou SM (1965). Particles resembling pa-povavirus in human cerebral demyelinating disease. Science 148: 1477–1479.

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