938
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Increased visceral adiposity index associated with sexual dysfunction in men

, , , &
Pages 187-192 | Received 09 Oct 2017, Accepted 14 Nov 2017, Published online: 22 Nov 2017

References

  • Montorsi F, Adaikan G, Becher E, et al. Summary of the recommendations on sexual dysfunctions in men. J Sex Med. 2010;7:3572–3588.
  • Fisher WA, Eardley I, McCabe M, et al. Erectile dysfunction (ED) is a shared sexual concern of couples I: couple conceptions of ED. J Sex Med. 2009;6:2746–2760.
  • Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int. 1999;84:50–56.
  • Seftel AD, Sun P, Swindle R. The prevalence of hypertension, hyperlipidemia, diabetes mellitus and depression in men with erectile dysfunction. J Urol. 2004;171:2341–2345.
  • Dong JY, Zhang YH, Qin LQ. Erectile dysfunction and risk of cardiovascular disease: meta-analysis of prospective cohort studies. J Am Coll Cardiol. 2011;58:1378–1385.
  • Johannes CB, Araujo AB, Feldman HA, et al. Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts male aging study. J Urol. 2000;163:460–463.
  • Panach-Navarrete J, Martínez-Jabaloyas JM, DE-SDT Study Group. The influence of comorbidities on the aging males' symptoms scale in patients with erectile dysfunction. Aging Male. 2017;20:146–152.
  • Corona G, Mannucci E, Fisher AD, et al. Low levels of androgens in men with erectile dysfunction and obesity. J Sex Med. 2008;5:2454–2463.
  • Lee RK, Chung D, Chughtai B, et al. Central obesity as measured by waist circumference is predictive of severity of lower urinary tract symptoms. BJU Int. 2012;110:540–545.
  • Saigal CS, Wessells H, Pace J, et al. Predictors and prevalence of erectile dysfunction in a racially diverse population. Arch Intern Med. 2006;166:207.
  • Bacon CG, Hu FB, Giovannucci E, et al. Association of type and duration of diabetes with erectile dysfunction in a large cohort of men. Diabetes Care. 2002;25:1458.
  • Corona G, Mannucci E, Petrone L, et al. A comparison of NCEPATPIII and IDF metabolic syndrome definitions with relation to metabolic syndrome-associated sexual dysfunction. J Sex Med. 2007;4:789–796.
  • Traish AM, Guay A, Feeley R, et al. The dark side of testosterone deficiency, I: metabolic syndrome and erectile dysfunction. J Androl. 2009;30:10–22.
  • Demir O, Akgul K, Akar Z, et al. Association between severity of lower urinary tract symptoms, erectile dysfunction and metabolic syndrome. Aging Male. 2009;12:29–34.
  • Fung MM, Bettencourt R, Barrett-Connor E. Heart disease risk factors predict erectile dysfunction 25 years later: the Rancho Bernardo Study. J Am Coll Cardiol. 2004;43:1405–1411.
  • Blaya R, Thomaz LD, Guilhermano F, et al. Total testosterone levels are correlated to metabolic syndrome components. Aging Male. 2016;19:85–89.
  • Amato MC, Giordano C, Galia M, et al. Visceral Adiposity Index: a reliable indicator of visceral fat function associated with cardiometabolic risk. Diabetes Care. 2010;33:920–922.
  • Guzik TJ, Mangalat D, Korbut R. Adipocytokines - novel link between inflammation and vascular function? J Physiol Pharmacol. 2006;57:505–528.
  • Goh VH, Hart WG. Association of general and abdominal obesity with age, endocrine and metabolic factors in Asian men. Aging Male. 2016;19:27–33.
  • Traish AM, Feeley RJ, Guay A. Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction. Febs J. 2009;276:5755–5767.
  • Monteagudo PT, Falcão AA, Verreschi IT, et al. The imbalance of sex-hormones related to depressive symptoms in obese men. Aging Male. 2016;19:20–26.
  • Cao J, Chen TM, Hao WJ, et al. Correlation between sex hormone levels and obesity in the elderly male. Aging Male. 2012;15:85–89.
  • Yassin DJ, Doros G, Hammerer PG, et al. Long-term testosterone treatment in elderly men with hypogonadism and erectile dysfunction reduces obesity parameters and improves metabolic syndrome and health-related quality of life. J Sex Med. 2014;11:1567–1576.
  • Salman M, Yassin DJ, Shoukfeh H, et al. Early weight loss predicts the reduction of obesity in men with erectile dysfunction and hypogonadism undergoing long-term testosterone replacement therapy. Aging Male. 2017;20:45–48.
  • Yassin A, Nettleship JE, Talib RA, et al. Effects of testosterone replacement therapy withdrawal and re-treatment in hypogonadal elderly men upon obesity, voiding function and prostate safety parameters. Aging Male. 2016;19:64–69.
  • Loves S, Ruinemans-Koerts J, de Boer H. Letrozole once a week normalizes serum testosterone in obesity-related male hypogonadism. Eur J Endocrinol. 2008;158:741–747.
  • Pitteloud N, Hardin M, Dwyer AA, et al. Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men. J Clin Endocrinol Metab. 2005;90:2636–2641.
  • Rotter I, Kosik-Bogacka D, Dołęgowska B, et al. Analysis of relationships between the concentrations of total testosterone and dehydroepiandrosterone sulfate and the occurrence of selected metabolic disorders in aging men. Aging Male. 2015;18:249–255.
  • Saad F, Yassin A, Almehmadi Y, et al. Effects of long-term testosterone replacement therapy, with a temporary intermission, on glycemic control of nine hypogonadal men with type 1 diabetes mellitus - a series of case reports. Aging Male. 2015;18:164–168.
  • Kaplan SA, Lee JY, O'Neill EA, et al. Prevalence of low testosterone and its relationship to body mass index in older men with lower urinary tract symptoms associated with benign prostatic hyperplasia. Aging Male. 2013;16:169–172.
  • Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev. 2005;26:439–451.
  • Correla ML, Rahmouni K. Role of leptin in the cardiovascular and endocrine complications of metabolic syndrome. Diabetes Obes Metab. 2006;8:603–610.
  • Larsen SH, Wagner G, Heitmann BL. Sexual function and obesity. Int J Obes (Lond). 2007;31: 1189–1198.
  • Bacon CG, Mittleman MA, Kawachi I, et al. A prospective study of risk factors for erectile dysfunction. J Urol. 2006;176:217–221.
  • Janiszewski PM, Janssen I, Ross R. Abdominal obesity and physical inactivity are associated with erectile dysfunction independent of body mass index. J Sex Med. 2009;6:1990–1998.
  • Riedner CE, Rhoden EL, Ribeiro EP, et al. Central obesity is an independent predictor of erectile dysfunction in older men. J Urol. 2006;176:1519–1523.
  • Okosun IS, Chandra KM, Boev A, et al. Abdominal adiposity in U.S. adults: prevalence and trends, 1960-2000. Prev Med. 2004;39:197–206.
  • Li C, Ford ES, McGuire LC, et al. Increasing trends in waist circumference and abdominal obesity among US adults. Obesity (Silver Spring). 2007;15:216–224.
  • Mathieu P, Pibarot P, Larose E, et al. Visceral obesity and the heart. Int J Biochem Cell Biol. 2008;40:821–836.
  • Costanzo P, Knoblovits P, Valzacchi GR, et al. Erectile dysfunction is associated with a high prevalence of obesity and metabolic syndrome. Rev Argent Endocrinol Metab. 2008;45:142–148.
  • Esposito K, Giugliano F, Palo CD, et al. Effect of lifestyle changes on erectile dysfunction in obese men: a randomized controlled trial. JAMA. 2004;291:2978–2984.
  • Lemieux I, Pascot A, Cuouillard C, et al. Hypertriglyceridemic waist: a marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men? Circulation. 2000;102:179–184.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.