Effects of garden cress, fenugreek and black seed on the pharmacodynamics of metoprolol: an herb-drug interaction study in rats with hypertension

References

• Abdel-Rahman RF, Hessin AF, Abdelbaset M, Ogaly HA, Abd-Elsalam RM, Hassan SM. 2017. Antihypertensive effects of Roselle-Olive combination in L-NAME-induced hypertensive rats. Oxid Med Cell Longev. 2017:9460653.
   PubMed Web of Science ®Google Scholar
• Adaramoye OA, Nwosu IO, Farombi EO. 2012. Sub-acute effect of N(G)-nitro-l-arginine methyl-ester (L-NAME) on biochemical indices in rats: protective effects of kolaviron and extract of Curcuma longa L. Phcog Res. 4(3):127–133.
   Google Scholar
• Agrawal M, Nandini D, Sharma V, Chauhan NS. 2010. Herbal remedies for treatment of hypertension. Int J Pharm Sci Res. 1:1–21.
   Google Scholar
• Ahad A, Al-Jenoobi FI, Al-Mohizea AM, Akhtar N, Raish M, Aqil M. 2015. Systemic delivery of β-blockers via transdermal route for hypertension . Saudi Pharm J. 23(6):587–602.
   PubMed Web of Science ®Google Scholar
• Ahad A, Al-Saleh AA, Al-Mohizea AM, Al-Jenoobi FI, Raish M, Yassin AEB, Alam MA. 2017. Pharmacodynamic study of eprosartan mesylate-loaded transfersomes Carbopol® gel under Dermaroller® on rats with methyl prednisolone acetate-induced hypertension. Biomed Pharmacother. 89:177–184.
   PubMed Web of Science ®Google Scholar
• Ahad A, Aqil M, Ali A. 2014. Investigation of antihypertensive activity of carbopol valsartan transdermal gel containing 1,8-cineole. Int J Biol Macromol. 64:144–149.
   PubMed Web of Science ®Google Scholar
• Ahad A, Aqil M, Kohli K, Sultana Y, Mujeeb M. 2015. Nano vesicular lipid carriers of angiotensin II receptor blocker: anti-hypertensive and skin toxicity study in focus. Artif Cells Nanomed Biotechnol. 44:1002–1007.
   PubMed Web of Science ®Google Scholar
• Ahad A, Raish M, Al-Jenoobi FI, Al-Mohizea AM. 2018. Sorbitane monostearate and cholesterol based niosomes for oral delivery of telmisartan. Curr Drug Deliv. 15(2):260–266.
   PubMed Web of Science ®Google Scholar
• Ahad A, Raish M, Bin Jardan YA, Alam MA, Al-Mohizea AM, Al-Jenoobi FI. 2020a. Effect of Hibiscus sabdariffa and Zingiber officinale on the antihypertensive activity and pharmacokinetic of losartan in hypertensive rats. Xenobiotica. 50(7):847–857.
   PubMed Web of Science ®Google Scholar
• Ahad A, Raish M, Bin Jardan YA, Alam MA, Al-Mohizea AM, Al-Jenoobi FI. 2020b. Potential pharmacodynamic and pharmacokinetic interactions of Nigella sativa and Trigonella foenum-graecum with losartan in L-NAME induced hypertensive rats. Saudi J Biol Sci. 27(10):2544–2550.
   PubMed Web of Science ®Google Scholar
• Ahmad A, Nabi R, Mishra A, Ahmad IZ. 2021. A panoramic review on Lepidium sativum L. bioactives as prospective therapeutics. Drug Res. 71(5):233–242.
   Google Scholar
• Al-Jenoobi FI, Ahad A, Mahrous GM, Al-Mohizea AM, AlKharfy KM, Al-Suwayeh SA. 2015. Effects of fenugreek, garden cress, and black seed on theophylline pharmacokinetics in beagle dogs. Pharm Biol. 53(2):296–300.
   PubMed Web of Science ®Google Scholar
• Al-Jenoobi FI, Al-Suwayeh SA, Muzaffar I, Alam MA, Al-Kharfy KM, Korashy HM, Al-Mohizea AM, Ahad A, Raish M. 2013. Effects of Nigella sativa and Lepidium sativum on cyclosporine pharmacokinetics. Biomed Res Int. 2013:953520.
   PubMed Web of Science ®Google Scholar
• Amin B, Hosseinzadeh H. 2016. Black cumin (Nigella sativa) and its active constituent, thymoquinone: an overview on the analgesic and anti-inflammatory effects. Planta Med. 82(1–2):8–16.
   PubMed Web of Science ®Google Scholar
• Archer JS. 2000. Evaluation and treatment of hypertension. Prim. Care Update Ob Gyns. 7(1):1–6.
   Google Scholar
• Balaraman R, Dangwal S, Mohan M. 2006. Antihypertensive effect of Trigonella foenumgreacum. seeds in experimentally induced hypertension in rats. Pharm Biol. 44(8):568–575.
   Web of Science ®Google Scholar
• Berger B, Bachmann F, Duthaler U, Krahenbuhl S, Haschke M. 2018. Cytochrome P450 enzymes involved in metoprolol metabolism and use of metoprolol as a CYP2D6 phenotyping probe drug. Front Pharmacol. 9:774.
   PubMed Web of Science ®Google Scholar
• Bernatova I. 2014. Endothelial dysfunction in experimental models of arterial hypertension: cause or consequence? Biomed Res Int. 2014:598271.
   PubMed Web of Science ®Google Scholar
• Bernatova I, Pechanova O, Simko F. 1999. Effect of captopril in L-NAME-induced hypertension on the rat myocardium, aorta, brain and kidney. Exp Physiol. 84(6):1095–1105.
   PubMed Web of Science ®Google Scholar
• Bushra R, Aslam N, Khan AY. 2011. Food-drug interactions. Oman Med J. 26(2):77–83.
   PubMedGoogle Scholar
• Butt AS, Nisar N, Mughal TA, Ghani N, Altaf I. 2019. Anti-oxidative and anti-proliferative activities of extracted phytochemical compound thymoquinone. J Pak Med Assoc. 69(0):1–1485.
   Google Scholar
• Cardoso AM, Abdalla FH, Bagatini MD, Martins CC, da Silva Fiorin F, Baldissarelli J, Costa P, de Mello FF, Fiorenza AM, da Silva Serres JD, et al. 2014. Swimming training prevents alterations in acetylcholinesterase and butyrylcholinesterase activities in hypertensive rats. Am J Hypertens. 27(4):522–529.
   PubMed Web of Science ®Google Scholar
• Chatoui K, Harhar H, El Kamli T, Tabyaoui M. 2020. Chemical composition and antioxidant capacity of Lepidium sativum seeds from four regions of Morocco. Evid Based Complement Alternat Med. 2020:7302727.
   PubMed Web of Science ®Google Scholar
• Darakhshan S, Bidmeshki Pour A, Hosseinzadeh Colagar A, Sisakhtnezhad S. 2015. Thymoquinone and its therapeutic potentials. Pharmacol Res. 95–96:138–158.
   PubMed Web of Science ®Google Scholar
• Dehkordi FR, Kamkhah AF. 2008. Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. Fundam Clin Pharmacol. 22(4):447–452.
   PubMed Web of Science ®Google Scholar
• Doke S, Guha M. 2014. Garden cress (Lepidium sativum L.) seed – an important medicinal source: a review. J Nat Prod Plant Resour. 4:69–80.
   Google Scholar
• Enayatfard L, Mohebbati R, Niazmand S, Hosseini M, Shafei MN. 2018. The standardized extract of Nigella sativa and its major ingredient, thymoquinone, ameliorates angiotensin II-induced hypertension in rats. J Basic Clin Physiol Pharmacol. 30(1):51–58.
   PubMedGoogle Scholar
• Fasinu PS, Bouic PJ, Rosenkranz B. 2012. An overview of the evidence and mechanisms of herb-drug interactions. Front Pharmacol. 3:69.
   PubMed Web of Science ®Google Scholar
• Feng M, Deerhake ME, Keating R, Thaisz J, Xu L, Tsaih SW, Smith R, Ishige T, Sugiyama F, Churchill GA, et al. 2009. Genetic analysis of blood pressure in 8 mouse intercross populations. Hypertension. 54(4):802–809.
   PubMed Web of Science ®Google Scholar
• Geberemeskel GA, Debebe YG, Nguse NA. 2019. Antidiabetic effect of fenugreek seed powder solution (Trigonella foenum-graecum L.) on hyperlipidemia in diabetic patients. J Diabetes Res. 2019:1–8.
   Web of Science ®Google Scholar
• Gholamnezhad Z, Havakhah S, Boskabady MH. 2016. Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: a review. J Ethnopharmacol. 190:372–386.
   PubMed Web of Science ®Google Scholar
• Grassi G. 2018. Metoprolol in the treatment of cardiovascular disease: a critical reappraisal. Curr Med Res Opin. 34(9):1635–1643.
   PubMed Web of Science ®Google Scholar
• Hamdan A, Haji Idrus R, Mokhtar MH. 2019. Effects of Nigella sativa on type-2 diabetes mellitus: a systematic review. Int J Environ Res Public Health. 16(24):4911.
   PubMed Web of Science ®Google Scholar
• Ijaz H, Tulain UR, Qureshi J, Danish Z, Musayab S, Akhtar MF, Saleem A, Khan KK, Zaman M, Waheed I, et al. 2017. Review: Nigella sativa (prophetic medicine): a review. Pak J Pharm Sci. 30(1):229–234.
   PubMed Web of Science ®Google Scholar
• Jaarin K, Foong WD, Yeoh MH, Kamarul ZY, Qodriyah HM, Azman A, Zuhair JS, Juliana AH, Kamisah Y. 2015. Mechanisms of the antihypertensive effects of Nigella sativa oil in L-NAME-induced hypertensive rats. Clinics. 70(11):751–757.
   PubMed Web of Science ®Google Scholar
• Johansson T, Weidolf L, Jurva U. 2007. Mimicry of phase I drug metabolism-novel methods for metabolite characterization and synthesis. Rapid Commun Mass Spectrom. 21(14):2323–2331.
   PubMed Web of Science ®Google Scholar
• Kobayashi N, Hara K, Watanabe S, Higashi T, Matsuoka H. 2000. Effect of imidapril on myocardial remodeling in L-NAME-induced hypertensive rats is associated with gene expression of NOS and ACE mRNA. Am J Hypertens. 13(2):199–207.
   PubMed Web of Science ®Google Scholar
• Kooti W, Hasanzadeh-Noohi Z, Sharafi-Ahvazi N, Asadi-Samani M, Ashtary-Larky D. 2016. Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa). Chin J Nat Med. 14(10):732–745.
   PubMed Web of Science ®Google Scholar
• Krege JH, Hodgin JB, Hagaman JR, Smithies O. 1995. A noninvasive computerized tail-cuff system for measuring blood pressure in mice. Hypertension. 25(5):1111–1115.
   PubMed Web of Science ®Google Scholar
• Madar Z, Shomer I. 1990. Polysaccharide composition of a gel fraction derived from fenugreek and its effect on starch digestion and bile acid absorption in rats. J Agric Food Chem. 38(7):1535–1539.
   Web of Science ®Google Scholar
• Maghrani M, Zeggwagh NA, Michel JB, Eddouks M. 2005. Antihypertensive effect of Lepidium sativum L. in spontaneously hypertensive rats. J Ethnopharmacol. 100(1–2):193–197.
   PubMed Web of Science ®Google Scholar
• Majdalawieh AF, Fayyad MW, Nasrallah GK. 2017. Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa. Crit Rev Food Sci Nutr. 57(18):3911–3928.
   PubMed Web of Science ®Google Scholar
• Mali VR, Mohan V, Bodhankar SL. 2012. Antihypertensive and cardioprotective effects of the Lagenaria siceraria fruit in NG-nitro-L-arginine methyl ester (L-NAME) induced hypertensive rats. Pharm Biol. 50(11):1428–1435.
   PubMed Web of Science ®Google Scholar
• Mansoor GA. 2001. Herbs and alternative therapies in the hypertension clinic. Am J Hypertens. 14(9 Pt 1):971–975.
   PubMed Web of Science ®Google Scholar
• Mills KT, Bundy JD, Kelly TN, Reed JE, Kearney PM, Reynolds K, Chen J, He J. 2016. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 134(6):441–450.
   PubMed Web of Science ®Google Scholar
• Mills KT, Stefanescu A, He J. 2020. The global epidemiology of hypertension. Nat Rev Nephrol. 16(4):223–237.
   PubMed Web of Science ®Google Scholar
• Modak M, Dixit P, Londhe J, Ghaskadbi S, Devasagayam TP. 2007. Indian herbs and herbal drugs used for the treatment of diabetes. J Clin Biochem Nutr. 40(3):163–173.
   PubMed Web of Science ®Google Scholar
• Mollazadeh H, Afshari AR, Hosseinzadeh H. 2017. Review on the potential therapeutic roles of Nigella sativa in the treatment of patients with cancer: involvement of apoptosis: Black cumin and cancer. J Pharmacopuncture. 20(3):158–172.
   PubMed Web of Science ®Google Scholar
• Morani AS, Bodhankar SL, Mohan V, Thakurdesai PA. 2012. Ameliorative effects of standardized extract from Trigonella foenum-graecum L. seeds on painful peripheral neuropathy in rats. Asian Pac J Trop Med. 5(5):385–390.
   PubMed Web of Science ®Google Scholar
• Nagulapalli Venkata KC, Swaroop A, Bagchi D, Bishayee A. 2017. A small plant with big benefits: Fenugreek (Trigonella foenum-graecum Linn.) for disease prevention and health promotion. Mol Nutr Food Res. 61:1–26.
   Web of Science ®Google Scholar
• Nair S, Nagar R, Gupta R. 1998. Antioxidant flavonoids in common Indian diet. J Assoc Physicians India. 46:708–710.
   PubMedGoogle Scholar
• Palleria C, Di Paolo A, Giofre C, Caglioti C, Leuzzi G, Siniscalchi A, De Sarro G, Gallelli L. 2013. Pharmacokinetic drug-drug interaction and their implication in clinical management. J Res Med Sci. 18(7):601–610.
   PubMed Web of Science ®Google Scholar
• Patel DK, Prasad SK, Kumar R, Hemalatha S. 2012. An overview on antidiabetic medicinal plants having insulin mimetic property. Asian Pac J Trop Biomed. 2(4):320–330.
   PubMedGoogle Scholar
• Petit PR, Sauvaire YD, Hillaire-Buys DM, Leconte OM, Baissac YG, Ponsin GR, Ribes GR. 1995. Steroid saponins from fenugreek seeds: extraction, purification, and pharmacological investigation on feeding behavior and plasma cholesterol. Steroids. 60(10):674–680.
   PubMed Web of Science ®Google Scholar
• Prajapati VD, Maheriya PM, Jani GK, Patil PD, Patel BN. 2014. Lepidium sativum Linn.: a current addition to the family of mucilage and its applications. Int J Biol Macromol. 65:72–80.
   PubMed Web of Science ®Google Scholar
• Ramanathan V, Thekkumalai M. 2014. Role of chrysin on hepatic and renal activities of N-nitro-L-arginine-methylester induced hypertensive rats. Int J Nutr Pharmacol Neurol Dis. 4(1):58–63.
   Google Scholar
• Reddy RR, Srinivasan K. 2011. Dietary fenugreek and onion attenuate cholesterol gallstone formation in lithogenic diet-fed mice. Int J Exp Pathol. 92(5):308–319.
   PubMed Web of Science ®Google Scholar
• Regardh CG, Johnsson G. 1980. Clinical pharmacokinetics of metoprolol. Clin Pharmacokinet. 5(6):557–569.
   PubMed Web of Science ®Google Scholar
• Rehman NU, Khan AU, Alkharfy KM, Gilani AH. 2012. Pharmacological basis for the medicinal use of Lepidium sativum in airways disorders. Evid Based Complement Alternat Med. 2012:596524.
   PubMed Web of Science ®Google Scholar
• Rigby JW, Scott AK, Hawksworth GM, Petrie JC. 1985. A comparison of the pharmacokinetics of atenolol, metoprolol, oxprenolol and propranolol in elderly hypertensive and young healthy subjects. Br J Clin Pharmacol. 20(4):327–331.
   PubMed Web of Science ®Google Scholar
• Ripley TL, Saseen JJ. 2014. β-blockers: a review of their pharmacological and physiological diversity in hypertension. Ann Pharmacother. 48(6):723–733.
   PubMed Web of Science ®Google Scholar
• Rizka A, Setiati S, Lydia A, Dewiasty E. 2017. Effect of Nigella sativa seed extract for hypertension in elderly: a double-blind, randomized controlled trial. Acta Med Indones. 49(4):307–313.
   PubMed Web of Science ®Google Scholar
• Sung JH, Jo YS, Kim SJ, Ryu JS, Kim MC, Ko HJ, Sim SS. 2013. Effect of lutein on L-NAME-induced hypertensive rats. Korean J Physiol Pharmacol. 17(4):339–345.
   PubMed Web of Science ®Google Scholar
• Susalit E, Agus N, Effendi I, Tjandrawinata RR, Nofiarny D, Perrinjaquet-Moccetti T, Verbruggen M. 2011. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with Captopril. Phytomedicine. 18(4):251–258.
   PubMed Web of Science ®Google Scholar
• Syed AA, Lahiri S, Mohan D, Valicherla GR, Gupta AP, Riyazuddin M, Kumar S, Maurya R, Hanif K, Gayen JR. 2016. Evaluation of anti-hypertensive activity of Ulmus wallichiana extract and fraction in SHR, DOCA-salt- and L-NAME-induced hypertensive rats. J Ethnopharmacol. 193:555–565.
   PubMed Web of Science ®Google Scholar
• Tabassum N, Ahmad F. 2011. Role of natural herbs in the treatment of hypertension. Pharmacogn Rev. 5(9):30–40.
   PubMedGoogle Scholar
• Tata CM, Sewani-Rusike CR, Oyedeji OO, Gwebu ET, Mahlakata F, Nkeh-Chungag BN. 2019. Antihypertensive effects of the hydro-ethanol extract of Senecio serratuloides DC in rats. BMC Complement Altern Med. 19(1):52.
   PubMedGoogle Scholar
• Tavakkoli A, Mahdian V, Razavi BM, Hosseinzadeh H. 2017. Review on clinical trials of black seed (Nigella sativa ) and Its Active Constituent, Thymoquinone. J Pharmacopuncture. 20(3):179–193.
   PubMed Web of Science ®Google Scholar
• Xiao J, Ke ZP, Shi Y, Zeng Q, Cao Z. 2018. The cardioprotective effect of thymoquinone on ischemia-reperfusion injury in isolated rat heart via regulation of apoptosis and autophagy. J Cell Biochem. 119(9):7212–7217.
   PubMed Web of Science ®Google Scholar
• Yadav UC, Baquer NZ. 2014. Pharmacological effects of Trigonella foenum-graecum L. in health and disease. Pharm Biol. 52(2):243–254.
   PubMed Web of Science ®Google Scholar
• Yoshikawa M, Murakami T, Komatsu H, Murakami N, Yamahara J, Matsuda H. 1997. Medicinal foodstuffs. IV. Fenugreek seed. (1): structures of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, new furostanol saponins from the seeds of Indian Trigonella foenum-graecum L. Chem Pharm Bull. 45(1):81–87.
   PubMed Web of Science ®Google Scholar
• Zhao X, Ho D, Gao S, Hong C, Vatner DE, Vatner SF. 2011. Arterial pressure monitoring in mice. Curr Protoc Mouse Biol. 1:105–122.
   PubMedGoogle Scholar