Comparison of the efficacy of depot GnRH agonist protocol and the GnRH antagonist protocol in patients with repeated IVF failure: a retrospective cohort study

References

• Al-Inany, H. G., Youssef, M. A., Ayeleke, R. O., Brown, J., Lam, W. S., & Broekmans, F. J. (2016). Gonadotrophin-releasing hormone antagonists for assisted reproductive technology. The Cochrane Database of Systematic Reviews, 4(4), CD001750. https://doi.org/10.1002/14651858.CD001750.pub4
   PubMedGoogle Scholar
• Boucret, L., Bouet, P. E., Riou, J., Legendre, G., Delbos, L., Hachem, H. E., Descamps, P., Reynier, P., & May-Panloup, P. (2020). Endometriosis lowers the cumulative live birth rates in ivf by decreasing the number of embryos but not their quality. Journal of Clinical Medicine, 9(8), 2478. https://doi.org/10.3390/jcm9082478
   PubMed Web of Science ®Google Scholar
• Busnelli, A., Reschini, M., Cardellicchio, L., Vegetti, W., Somigliana, E., & Vercellini, P. (2020). How common is real repeated implantation failure? An indirect estimate of the prevalence. Reproductive Biomedicine Online, 40(1), 91–97. https://doi.org/10.1016/j.rbmo.2019.10.014
   PubMed Web of Science ®Google Scholar
• Chen, Q., Fan, Y., Zhou, X., Yan, Z., Kuang, Y., Zhang, A., & Xu, C. (2020). GnRH antagonist alters the migration of endometrial epithelial cells by reducing CKB. Reproduction, 159(6), 733–743. https://doi.org/10.1530/REP-19-0578
   PubMed Web of Science ®Google Scholar
• Chen, Q., Yu, F., Li, Y., Zhang, A. J., & Zhu, X. B. (2019). Comparative proteomics reveal negative effects of gonadotropin-releasing hormone agonist and antagonist on human endometrium. Drug Design, Development and Therapy, 13, 1855–1863. https://doi.org/10.2147/DDDT.S201871
   PubMed Web of Science ®Google Scholar
• Coughlan, C., Ledger, W., Wang, Q., Liu, F., Demirol, A., Gurgan, T., Cutting, R., Ong, K., Sallam, H., & Li, T. C. (2014). Recurrent implantation failure: Definition and management. Reproductive Biomedicine Online, 28(1), 14–38. https://doi.org/10.1016/j.rbmo.2013.08.011
   PubMed Web of Science ®Google Scholar
• Dahdouh, E. M., Balayla, J., & García-Velasco, J. A. (2015). Comprehensive chromosome screening improves embryo selection: A meta-analysis. Fertility and Sterility, 104(6), 1503–1512. https://doi.org/10.1016/j.fertnstert.2015.08.038
   PubMed Web of Science ®Google Scholar
• Franasiak, J. M., & Scott, R. T. (2017). Contribution of immunology to implantation failure of euploid embryos. Fertility and Sterility, 107(6), 1279–1283. https://doi.org/10.1016/j.fertnstert.2017.04.019
   PubMed Web of Science ®Google Scholar
• Gendelman, M., & Roth, Z. (2012). Incorporation of coenzyme Q10 into bovine oocytes improves mitochondrial features and alleviates the effects of summer thermal stress on developmental competence. Biology of Reproduction, 87(5), 118. https://doi.org/10.1095/biolreprod.112.101881
   PubMed Web of Science ®Google Scholar
• Geng, Y., Xun, Y., Hu, S., Lai, Q., & Jin, L. (2019). GnRH antagonist versus follicular-phase single-dose GnRH agonist protocol in patients of normal ovarian responses during controlled ovarian stimulation. Gynecological Endocrinology, 35(4), 309–313. https://doi.org/10.1080/09513590.2018.1528221
   PubMed Web of Science ®Google Scholar
• Gleicher, N., Kim, A., Michaeli, T., Lee, H. J., Shohat-Tal, A., Lazzaroni, E., & Barad, D. H. (2013). A pilot cohort study of granulocyte colony-stimulating factor in the treatment of unresponsive thin endometrium resistant to standard therapies. Human Reproduction, 28(1), 172–177. https://doi.org/10.1093/humrep/des370
   PubMed Web of Science ®Google Scholar
• Hviid, M. M., & Macklon, N. (2017). Immune modulation treatments-where is the evidence? Fertility and Sterility, 107(6), 1284–1293. https://doi.org/10.1016/j.fertnstert.2017.04.009
   PubMed Web of Science ®Google Scholar
• Kuivasaari, P., Hippeläinen, M., Anttila, M., & Heinonen, S. (2005). Effect of endometriosis on IVF/ICSI outcome: Stage III/IV endometriosis worsens cumulative pregnancy and live-born rates. Human Reproduction, 20(11), 3130–3135. https://doi.org/10.1093/humrep/dei176
   PubMed Web of Science ®Google Scholar
• Lambalk, C. B., Banga, F. R., Huirne, J. A., Toftager, M., Pinborg, A., Homburg, R., van der Veen, F., & van Wely, M. (2017). GnRH antagonist versus long agonist protocols in IVF: A systematic review and meta-analysis accounting for patient type. Human Reproduction Update, 23(5), 560–579. https://doi.org/10.1093/humupd/dmx017
   PubMed Web of Science ®Google Scholar
• Liu, K. E., Hartman, M., Hartman, A., Luo, Z. C., & Mahutte, N. (2018). The impact of a thin endometrial lining on fresh and frozen-thaw IVF outcomes: An analysis of over 40 000 embryo transfers. Human Reproduction, 33(10), 1883–1888. https://doi.org/10.1093/humrep/dey281
   PubMed Web of Science ®Google Scholar
• Ren, J., Sha, A., Han, D., Li, P., Geng, J., & Ma, C. (2014). Does prolonged pituitary down-regulation with gonadotropin-releasing hormone agonist improve the live-birth rate in in vitro fertilization treatment? Fertility and Sterility, 102(1), 75–81. https://doi.org/10.1016/j.fertnstert.2014.03.030
   PubMed Web of Science ®Google Scholar
• Ruan, H. C., Huang, H. F., & Jin, F. (2004). The expression of integrin beta3 in mice’s endometrium during the implantation window based on different ovarian stimulation protocols. Zhonghua yi Xue za Zhi, 84(10), 857–860.
   PubMedGoogle Scholar
• Sallam, H. N., Garcia-Velasco, J. A., Dias, S., & Arici, A. (2006). Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. The Cochrane Database of Systematic Reviews, 2006(1), CD004635. https://doi.org/10.1002/14651858.CD004635.pub2
   PubMedGoogle Scholar
• Scalea, J. R., Torabi, R., Tena, A., Tasaki, M., Gillon, B. C., Moran, S., Cormack, T., Villani, V., Shimizu, A., Sachs, D. H., & Yamada, K. (2014). The rejuvenating effects of leuprolide acetate on the aged baboon’s thymus. Transplant Immunology, 31(3), 134–139. https://doi.org/10.1016/j.trim.2014.09.001
   PubMed Web of Science ®Google Scholar
• Simon, A., & Laufer, N. (2012). Repeated implantation failure: Clinical approach. Fertility and Sterility, 97(5), 1039–1043. https://doi.org/10.1016/j.fertnstert.2012.03.010
   PubMed Web of Science ®Google Scholar
• Thornhill, A. R., deDie-Smulders, C. E., Geraedts, J. P., Harper, J. C., Harton, G. L., Lavery, S. A., Moutou, C., Robinson, M. D., Schmutzler, A. G., Scriven, P. N., Sermon, K. D., & Wilton, L, (2005). ESHRE PGD Consortium 'Best practice guidelines for clinical preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). Human Reproduction, 20(1), 35–48. https://doi.org/10.1093/humrep/deh579
   PubMed Web of Science ®Google Scholar
• Tremellen, K., & Russell, P. (2011). Adenomyosis is a potential cause of recurrent implantation failure during IVF treatment. The Australian & New Zealand Journal of Obstetrics & Gynaecology, 51(3), 280–283. https://doi.org/10.1111/j.1479-828X.2010.01276.x
   PubMed Web of Science ®Google Scholar
• Ullewar, M. P., & Umathe, S. N. (2014). Gonadotropin-releasing hormone agonist selectively augments thymopoiesis and prevents cell apoptosis in LPS induced thymic atrophy model independent of gonadal steroids. International Immunopharmacology, 23(1), 46–53. https://doi.org/10.1016/j.intimp.2014.07.032
   PubMed Web of Science ®Google Scholar
• Unfer, V., Raffone, E., Rizzo, P., & Buffo, S. (2011). Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: A prospective, longitudinal, cohort study. Gynecological Endocrinology27(11), 857–861. https://doi.org/10.3109/09513590.2011.564687
   PubMed Web of Science ®Google Scholar
• Xu, B., Geerts, D., Hu, S., Yue, J., Li, Z., Zhu, G., & Jin, L. (2020). The depot GnRH agonist protocol improves the live birth rate per fresh embryo transfer cycle, but not the cumulative live birth rate in normal responders: A randomized controlled trial and molecular mechanism study. Human Reproduction, 35(6), 1306–1318. https://doi.org/10.1093/humrep/deaa086
   PubMed Web of Science ®Google Scholar
• Xu, B., Zhou, M., Wang, J., Zhang, D., Guo, F., Si, C., Leung, P. C. K., & Zhang, A. (2018). Increased AIF-1-mediated TNF-α expression during implantation phase in IVF cycles with GnRH antagonist protocol. Human Reproduction, 33(7), 1270–1280. https://doi.org/10.1093/humrep/dey119
   PubMed Web of Science ®Google Scholar
• Yang, X., Huang, R., Wang, Y. F., & Liang, X. Y. (2016). Pituitary suppression before frozen embryo transfer is beneficial for patients suffering from idiopathic repeated implantation failure. Journal of Huazhong University of Science and Technology, 36(1), 127–131. https://doi.org/10.1007/s11596-016-1554-2
   PubMedGoogle Scholar
• Zhang, Y., Xu, H., Liu, Y., Zheng, S., Zhao, W., Wu, D., Lei, L., & Chen, G. (2019). Confirmation of chronic endometritis in repeated implantation failure and success outcome in IVF-ET after intrauterine delivery of the combined administration of antibiotic and dexamethasone. American Journal of Reproductive Immunology, 82(5), e13177. https://doi.org/10.1111/aji.13177
   PubMed Web of Science ®Google Scholar