Immunomodulatory effects of fetal and adult mesenchymal stem cells

References

• Friedenstein AJ, Petrakova KV, Kuroksova AI et al. Heterotopic transplants of bone marrow: analysis of precursor cells for osteogenic and hematopoietic tissue. Transplantation 1968;6:230 — 47.
   Google Scholar
• Haynesworth SE, Goshima J, Goldberg VM et al. Characteriza-tion of cells with osteogenic potential from human marrow. Bone 1992;13:81 — 8.
   Google Scholar
• Prockop DJ. Marrow stromal cells as stem cells for nonhema-topoietic tissues. Science 1997;276:71 — 4.
   PubMedGoogle Scholar
• Pittenger MF, Mackay AM, Beck SC et al. Multi-lineage potential of adult human mesenchymal stem cells. Science 1999;284:143— 7.
   PubMed Web of Science ®Google Scholar
• Campagnoli C, Roberts IA, Kumar S et al. Identification of mesenchymal stem/progenitor cells in human first- trimester fetal blood, liver, and bone marrow. Blood 2001;98:2396–402.
   PubMed Web of Science ®Google Scholar
• Götherström C, Ringdén 0, Westgren M et al. Immunomodu-latory effects of human foetal liver-derived mesenchymal stem cells. Bone Marrow Transplant 2003;32:265— 72.
   Google Scholar
• Haynesworth SE, Saber MA, Caplan Al. Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies. Bone 1992;13:69— 80.
   Google Scholar
• Deans RJ, Moseley A-M. Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 2000;28:875–84.
   Google Scholar
• Majumdar MK, Thiede MA, Mosca JD et al. Phenotypic and functional comparison of cultures of marrow-derived mesench-ymal stem cells (MSC) and stromal cells. 7 Cell Physiol 1998;176:186–92.
   Google Scholar
• Noort WA, Kruisselbrink AB, Anker PS et al. Mesenchymal stemcells promote engraftment of human umbilical cord blood-derived CD34± cells in NOD/SCID mice. Exp Hematol 2002;30:870— 8.
   Google Scholar
• Angelopoulou M, Novelli E, Grove J et al. Cotransplantation ofhuman mesenchymal stem cells enhances human myelopoesis and megakaryocytopoiesis in NOD/SCID mice. Exp Hematol 2003;31:413–20.
   PubMed Web of Science ®Google Scholar
• Pereira RF, Halford KW, O'Hara MD et al. Cultured adherent cells from marrow can serve as long-lasting precursors for bone, cartilage, and lung in irradiated mice. Proc Natl Acad Sci USA 1995;92:4857–61.
   Google Scholar
• Liechty KW, MacKenzie TC, Shaaban AF et al. Human mesenchymal stem cells engraft and demonstrate site- specific differentiation after in utero transplantation in sheep. Nat Med 2000;6:1282–6.
   PubMed Web of Science ®Google Scholar
• Devine SM, Cobbs C, Jennings M et al. Mesenchymal stem cellsdistribute to a wide range of tissues following systemic infusion into non-human primates. Blood 2003;101:2999–3001.
   PubMed Web of Science ®Google Scholar
• Tse WT, Pendleton JD, Beyer WM et al. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation. Transplantation 2003;75:389–97.
   PubMed Web of Science ®Google Scholar
• Majumdar M, Keane-Moore M, Buyaner D et al. Characteriza-tion and functionality of cell surface molecules on human mesencymal stem cells. 7 Biomed Sci 2003;10: 228–41.
   Google Scholar
• Le Blanc K, Tammik L, Zetterberg E, Rosendahl K, Ringden 0. HLA-expression and immunologic properties of undifferen-tiated and differentiated mesenchymal stem cells. Exp Hematol In press.
   Google Scholar
• Gotherström C, Ringdén 0, Tammik C et al. Immunological properties of human fetal mesenchymal stem cells". Am 7 Obst Gynecol 2003;31: 890— 6.
   Google Scholar
• McIntosh K, Bartholomew A. Stromal cell modulation of the immune system. Graft 2000;3:324–8.
   Google Scholar
• Di Nicola M, Carlo-Stella C, Magni M et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or non-specific mitogenic stimuli. Blood 2002;99:3838–43.
   PubMed Web of Science ®Google Scholar
• Krampera M, Glennie S, Dyson J et al. Bone marrow mesenchymal stem cells inhibit the response of naive antigen specific T-cells to their cognate peptide. Blood 2003;101:3722–9.
   PubMed Web of Science ®Google Scholar
• Wilson JL, Proud G, Forsythe J et al. Renal allograft rejection.Tubular epithelial cells present alloantigen in the presence of costimulatory CD28 antibody. Transplantation 1995;59:91–7.
   Google Scholar
• Laning J, Deluca JE, Isaacs C et al. In vitro analysis of CD40-CD154 and CD28-CD80/86 interactions in the prmary T-cell response to allogeneic 'nonprofessional' antigen presenting cells. Transplantation 2001;71:1467— 74.
   Google Scholar
• Bartholomew A, Patil S, Mackay A et al. Baboon mesenchymalstem cells can be genetically modified to secrete human erythropoietin in vivo. Hum Gene Therapy 2001;12:1527–91.
   PubMed Web of Science ®Google Scholar
• Devine SM, Bartholomew AM, Mahmud N et al. Mesenchymalstem cells are capable of homing to the bone marrow of non-human primates following systemic infusion. Exp Hematol 2001;29:244— 55.
   Google Scholar
• Gurevitch 0, Prigozhina TB, Pugatsch T, Slavin S. Transplanta-tion of allogeneic or xenogenic bone marrow within the donor stromal microenvironment Transplantation 1999;68:1362— 8.
   Google Scholar
• Bingaman AV, Waitze SY, Alexander DZ et al. Transplantation ofthe bone marrow microenvironment leads to hematopoietic chimerism without cytoreductive conditioning. Transplantation 2000;69:2491–6.
   Google Scholar
• Yin D, Ma L, Zeng H, Sheen J, Zhong AS. Allograft toleranceinduced by intact active bone cotransplantation and anti-CD4OL monoclonal antibody therapy. Transplantation 2000;74: 345— 54.
   Google Scholar
• Bartholomew A, Sturgeon C, Siatskas M et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol 2002;30:42— 8.
   PubMedGoogle Scholar
• Le Blanc K, Tammik L, Sundberg B et al. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompat-ibility complex. Scand 7 Immunol 2003;57:11–20.
   PubMed Web of Science ®Google Scholar
• Frassoni F, Labopin M, Bacigalupo A et al. Expanded mesench-ymal stem cells (MSC), co-infused with HLA identical hema-topoietic stem cell transplants, reduce acute and chronic graft-versus-host disease: a matched pair analysis. Bone Marrow Transplant 2002;29(Suppl 2):52.
   Google Scholar
• Rasmusson I, Ringdén 0, Sundberg B, Le Blanc K. Mesench-ymal stem cells inhibit the formation of cytotoxic T lympho-cytes (CTL), but not activated CTL or natural killer (NK) cells. Transplantation 2003;76:1208— 13.
   Google Scholar