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Original Article

Optimal methods to characterize the G93A mouse model of ALS

, , , , , , & show all
Pages 55-62 | Received 21 Sep 2004, Accepted 27 Dec 2004, Published online: 10 Jul 2009

References

  • Fridovich I. Superoxide radical and superoxide dismutases. Annu Rev Biochem. 1995;64:97–112.
  • Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 1993;362:59–62.
  • Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD, Caliendo J, Hentati A, Kwon YW, Deng HX, et al. Motor neuron degeneration in mice that express a human Cu/Zn superoxide dismutase mutation. Science. 1994;264:1772–5.
  • Shibata N. Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. Neuropathology. 2001;21:82–92.
  • Drachman DB, Frank K, Dykes-Hoberg M, Teismann P, Almer G, Przedborski S, et al. Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS. Annals of Neurology. 2002;52:771–8.
  • Azzouz M, Leclerc N, Guney M, Warter JM, Poindron P, Borg J. Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis. Muscle & Nerve. 1997;20:45–51.
  • Weydt P, Hong SY, Kliot M, Moller T. Assessing disease onset and progression in the SOD1 mouse model of ALS. Neuroreport. 2003;14:1051–4.
  • Karl T, Pabst R, von Horsten S. Behavioural phenotyping of mice in pharmacological and toxicological research. Exp Toxicol Pathol. 2003;55:69–83.
  • Crawley JN. What’s wrong with my mouse? Behavioural phenotyping of transgenic and knockout mice (Wiley-Liss, New York, 2000).
  • Crawley JN. Behavioural phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioural tests. Brain Research. 1999; 835:18–26.
  • Dom´ınguez Alonso E, Gonza´lez Sua´rez R. Ana´lisis de las curvas Receiver-Operating Characteristic: un me´todo u´ til para evaluar procederes diagno´ sticos. Rev Cubana Endo- crinol. 2002;13:169–76.
  • Liu H, Wu T. Estimating the area under a Receiver Operating Characteristic curve for repeated measures design. Journal of Statistical Software. 2003;8.
  • Veldink JH, Bar PR, Joosten EA, Otten M, Wokke JH, van den Berg LH. Sexual differences in onset of disease and response to exercise in a transgenic model of ALS. Neuro- muscul Disord. 2003;13:737–43.
  • Dal Canto MC, Gurney ME. A low expressor line of transgenic mice carrying a mutant human Cu/Zn super- oxide dismutase (SOD1) gene develops pathological changes that most closely resemble those in human amyo- trophic lateral sclerosis. Acta Neuropathol (Berl). 1997; 93:537–50.
  • Ross MA, Miller RG, Berchert L, Parry G, Barohn RJ, Armon C, et al. Toward earlier diagnosis of amyotrophic lateral sclerosis: revised criteria. rhCNTF ALS Study Group. Neurology. 1998;50:768–72.

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