Plasma-derived exosomes in acute myeloid leukemia for detection of minimal residual disease: are we ready?

References

• Dombret H, Gardin C. An update of current treatments for adult acute myeloid leukemia. Blood. 2016;127(1):53–61.
   PubMed Web of Science ®Google Scholar
• Ferrara F, Schiffer CA. Acute myeloid leukaemia in adults. Lancet. 2013;381(9865):484–495.
   PubMed Web of Science ®Google Scholar
• Buckley SA, Appelbaum FR, Walter RB. Prognostic and therapeutic implications of minimal residual disease at the time of transplantation in acute leukemia. Bone Marrow Transplant. 2013;48(5):630–641.
   PubMed Web of Science ®Google Scholar
• Paietta E. Should minimal residual disease guide therapy in AML? Best Pract Res Clin Haematol. 2015;28(2–3):98–105.
   PubMed Web of Science ®Google Scholar
• Paietta E. Minimal residual disease in acute myeloid leukemia: coming of age. Hematol/Educ Program Am Soc Hematol Am Soc Hematol Educ Program. 2012;2012:35–42.
   PubMedGoogle Scholar
• Grimwade D, Freeman SD. Defining minimal residual disease in acute myeloid leukemia: which platforms are ready for “prime time”? Hematol/Educ Program Am Soc Hematol Am Soc Hematol Educ Program. 2014;2014(1):222–233.
   PubMed Web of Science ®Google Scholar
• Paietta E. Assessing minimal residual disease (MRD) in leukemia: a changing definition and concept? Bone Marrow Transplant. 2002;29(6):459–465.
   PubMed Web of Science ®Google Scholar
• Hokland P, Ommen HB, Mulé MP, et al. Advancing the minimal residual disease concept in acute myeloid leukemia. Semin Hematol. 2015;52(3):184–192.
   PubMed Web of Science ®Google Scholar
• Ivey A, Hills RK, Simpson MA, et al. Assessment of minimal residual disease in standard-risk AML. N Engl J Med. 2016;374(5):422–433.
   PubMed Web of Science ®Google Scholar
• Keller S, Ridinger J, Rupp A-K, et al. Body fluid derived exosomes as a novel template for clinical diagnostics. J Transl Med. 2011;9(1):86.
   PubMed Web of Science ®Google Scholar
• van der Pol E, Böing AN, Harrison P, et al. Classification, functions, and clinical relevance of extracellular vesicles. Pharmacol Rev. 2012;64(3):676–705.
   PubMed Web of Science ®Google Scholar
• Szczepanski MJ, Szajnik M, Welsh A, et al. Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1. Haematologica. 2011;96(9):1302–1309.
   PubMed Web of Science ®Google Scholar
• Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013;200(4):373–383.
   PubMed Web of Science ®Google Scholar
• Cocucci E, Meldolesi J. Ectosomes and exosomes: shedding the confusion between extracellular vesicles. Trends Cell Biol. 2015;25(6):364–372.
   PubMed Web of Science ®Google Scholar
• Andreau Z, Yanez-Mo M. Tetraspanins in extracellular vesicle formation and function. Front Immunol. 2014;5:1–12.
   PubMed Web of Science ®Google Scholar
• Théry C, Zitvogel L, Amigorena S. Exosomes: composition, biogenesis and function. Nat Rev Immunol. 2002;2(8):569–579.
   PubMed Web of Science ®Google Scholar
• Mulcahy LA, Pink RC, Carter DR. Routes and mechanisms of extracellular vesicle uptake. J Extracell Vesicles. 2014;3:24641.
   PubMedGoogle Scholar
• Atay S, Godwin AK. Tumor-derived exosomes: A message delivery system for tumor progression. Commun Integr Biol. 2014;7(1):e28231.
   PubMedGoogle Scholar
• Boyiadzis M, Whiteside TL. Information transfer by exosomes: a new frontier in hematologic malignancies. Blood Rev. 2015;29(5):281–290.
   PubMed Web of Science ®Google Scholar
• Taylor DD, Shah S. Methods of isolating extracellular vesicles impact down-stream analyses of their cargoes. Methods. 2015;87:3–10.
   PubMed Web of Science ®Google Scholar
• Muller L, Hong C-S, Stolz DB, et al. Isolation of biologically-active exosomes from human plasma. J Immunol Methods. 2014;411:55–65.
   PubMed Web of Science ®Google Scholar
• Welton JL, Webber JP, Botos L-A, et al. Ready-made chromatography columns for extracellular vesicle isolation from plasma. J Extracell Vesicles. 2015;4:27269.
   PubMed Web of Science ®Google Scholar
• Hong C, Funk S, Muller L, et al. Isolation of biologically-active and morphologically-intact exosomes from plasma of patients with cancer. J Extracell Vesicles. 2016;5:29289.
   PubMed Web of Science ®Google Scholar
• Hong CS, Muller L, Boyiadzis M, et al. Isolation and characterization of CD34+ blast-derived exosomes in acute myeloid leukemia. PLoS One. 2014;9(8):e103310.
   PubMed Web of Science ®Google Scholar
• Villarroya-Beltri C, Baixauli F, Gutiérrez-Vázquez C, et al. Sorting it out: regulation of exosome loading. Semin Cancer Biol. 2014;28:3–13.
   PubMed Web of Science ®Google Scholar
• Colombo M, Moita C, van Niel G, et al. Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci. 2013;126(Pt 24):5553–5565.
   PubMed Web of Science ®Google Scholar
• Boukouris S, Mathivanan S. Exosomes in bodily fluids are a highly stable resource of disease biomarkers. Proteomics Clin Appl. 2015;9(3–4):358–367.
   PubMed Web of Science ®Google Scholar
• Kahlert C, Kalluri R. Exosomes in tumor microenvironment influence cancer progression and metastasis. J Mol Med (Berl). 2013;91(4):431–437.
   PubMed Web of Science ®Google Scholar
• Melo SA, Luecke LB, Kahlert C, et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 2015;523(7559):177–182.
   PubMed Web of Science ®Google Scholar
• Hong C-S, Muller L, Whiteside TL, et al. Plasma exosomes as markers of therapeutic response in patients with acute myeloid leukemia. Front Immunol. 2014;5:160.
   PubMed Web of Science ®Google Scholar
• Boyiadzis MHC, Hong CS, Whiteside TL. Evidence for the role of biologically active exosomes in acute myeloid leukemia relapse. Blood. 2015;126(23).
   Web of Science ®Google Scholar
• Wojtuszkiewicz A, Schuurhuis GJ, Kessler FL, et al. Exosomes secreted by apoptosis-resistant acute myeloid leukemia (AML) blasts harbor regulatory network proteins potentially involved in antagonism of apoptosis. Mol Cell Proteomics. 2016;15(4):1281–1298.
   PubMed Web of Science ®Google Scholar
• Huan J, Hornick NI, Shurtleff MJ, et al. RNA trafficking by acute myelogenous leukemia exosomes. Cancer Res. 2013;73(2):918–929.
   PubMed Web of Science ®Google Scholar
• Hornick NI, Huan J, Doron B, et al. Serum exosome microRNA as a minimally-invasive early biomarker of AML. Sci Rep. 2015;5:11295.
   PubMed Web of Science ®Google Scholar
• Katsuda T, Kosaka N, Ochiya T. The roles of extracellular vesicles in cancer biology: toward the development of novel cancer biomarkers. Proteomics. 2014;14(4–5):412–425.
   PubMed Web of Science ®Google Scholar
• Whiteside TL. The potential of tumor-derived exosomes for noninvasive cancer monitoring. Expert Rev Mol Diagn. 2015;15:1293–1310.
   PubMed Web of Science ®Google Scholar
• Gould SJ, Raposo G. As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles. 2013;2:20389.
   PubMedGoogle Scholar
• Andreu Z, Yanez-Mo M. Tetraspanins in extracellular vesicle formation and function. Front Immunol. 2014;5:442.
   PubMed Web of Science ®Google Scholar
• Skog J, Wurdinger T, van Rijn S, et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008;10:1470–1476.
   PubMed Web of Science ®Google Scholar
• McShane LM, Altman DG, Sauerbrei W, et al. Reporting recommendations for tumor marker prognostic studies (REMARK). J Natl Cancer Inst. 2005;97(16):1180–1184.
   PubMed Web of Science ®Google Scholar