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Research Article

Inhibitory effects of diesel exhaust components and flavonoids on 20α-hydroxysteroid dehydrogenase activity in mouse tissues

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Pages 445-449 | Received 26 Jul 2006, Accepted 10 Nov 2006, Published online: 04 Oct 2008

References

  • Wiest WG, Wilcox RB. Purification and properties of rat ovarian 20α-hydroxysteroid dehydrogenase. J Biol Chem 1961; 236: 2425–2428
  • Wilcox RB, Wiest WG. Further studies of rat ovarian 20α-hydroxysteroid dehydrogenase. Steroids 1966; 7: 395–413
  • Ma H, Penning TM. Characterization of homogeneous recombinant rat ovarian 20α-hydroxysteroid dehydrogenase: fluorescent properties and inhibition profile. Biochem J 1999; 341: 853–859
  • Penning TM. Molecular endocrinology of hydroxysteroid dehydrogenases. Endocr Rev 1997; 18: 281–305
  • Petrelli EA, Forbes TR. Toxicity of progesterone to mouse fetuses. Endocrinol 1964; 75: 145–146
  • Ji Q, Aoyama C, Nien Y-D, Liu PI, Chen PK, Chang L, Stanczyk FZ, Stolz A. Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling. Cancer Res 2004; 64: 7610–7617
  • Wiebe JP, Lewis MJ, Cialacu V, Pawlak KJ, Zhang G. The role of progesterone metabolites in breast cancer: Potential for new diagnostics and therapeutics. J Steroid Biochem Mol Biol 2005; 93: 201–208
  • McClellan RO. Health effects of exposure to diesel exhaust particles. Annu Rev Pharmacol Toxicol 1987; 27: 279–300
  • Dockery DW, Pope ACIII, Xu X, Spengler JD, Ware JH, Fay ME, Ferris BG, Jr, Speizer FE. An association between air pollution and mortality in six U.S. cities. New Engl J Med 1993; 329: 1753–1759
  • Nel AE, Diaz-Sanchez D, Li N. The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress. Curr Opin Pulm Med 2001; 7: 20–26
  • Monks TJ, Hanzlik RP, Cohen GM, Ross D, Graham DG. Quinone chemistry and toxicology. Toxicol Appl Pharmacol 1992; 112: 2–16
  • Bolton JL, Trush MA, Penning TM. Role of quinones in toxicology. Chem Res Toxicol 2000; 13: 135–160
  • Schuetzle D. Sampling of vehicle emmissions for chemical analysis and biological testing. Environ Health Perspect 1983; 47: 65–80
  • Cho AK, Di Stefano E, You Y, Rodriguez CE, Schmitz D, Kumagai Y, Miguel AH, Eiguren-Fernandez AA, Kobayashi T, Vol A, Froines JR. Determination of four quinones in diesel exhaust particles, SRM 1649a, and atmospheric PM2.5. Aerosol Sci Technol 2004; 38: 68–81
  • Shimada H, Miura K, Imamura Y. Characteristics and inhibition by flavonoids of 20α-hydroxysteroid dehydrogenase activity in mouse tissues. Life Sci 2006; 78: 2931–2936
  • Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med 1996; 20: 933–956
  • Di Carlo G, Mascolo N, Izzo AA, Capasso F. Flavonoids: old and new aspects of a class of natural therapeutic drug. Life Sci 1999; 65: 337–353
  • Stopper H, Schmitt E, Kobras K. Genotoxicity of phytoestrogens. Mutat Res 2005; 574: 139–155
  • van der Woude H, Alink GM, van Rossum BEJ, Walle K, van Steeg H, Walle T, Rietjens IMCM. Formation of transient covalent protein and DNA adducts by quercetin in cells with and wothout oxidative enzyme activity. Chem Res Toxicol 2005; 18: 1907–1916
  • Morris ME, Zhang S. Flavonoid-drug interactions: Effects of flavonoids on ABC transporters. Life Sci 2006; 78: 2116–2130
  • Swinney DC, Ryan DE, Thomas PE, Levin W. Regioselective progesterone hydroxylation catalyzed by elever rat hepatic cytochrome P-450 isozymes. Biochemistry 1987; 26: 7073–7083
  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265–275
  • Matsumoto K, Endo S, Ishikura S, Matsunaga T, Tajima K, El-Kabbani O, Hara A. Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family. Biol Pharm Bull 2006; 29: 539–542
  • Ellis EM, Hayes JD. Substrate specificity of an aflatoxin-metabolizing aldehyde reductase. Biochem J 1995; 312: 535–541
  • Hinshelwood A, McGarvie G, Ellis EM. Substrate specificity of mouse aldo-keto reductase AKR7A5. Chem Biol Interact 2003; 143–144: 263–269
  • Kumagai Y, Nakajima H, Midorikawa K, Homma-Takeda S, Shimojo N. Inhibition of nitric oxide formation by nitric oxide synthase by quinones: Nitric oxide synthase as a quinone reductase. Chem Res Toxicol 1998; 11: 608–613
  • Shimada H, Oginuma M, Hara A, Imamura Y. 9, 10-Phenanthrenequinone, a component of diesel exhaust particles, inhibits the reduction of 4-benzoylpyridine and all-trans-retinal and mediates superoxide formation through its redox cycling in pig heart. Chem Res Toxicol 2004; 17: 1145–1150
  • Oginuma M, Shimada H, Imamura Y. Involvement of carbonyl reductase in superoxide formation through redox cycling of adrenochrome and 9,10-phenanthrenequinone in pig heart. Chem Biol Interact 2005; 155: 148–154
  • Rodriguez CE, Fukuto JM, Taguchi K, Froines J, Cho AK. The interactions of 9,10-phenanthrenequinone with glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a potential site for toxic actions. Chem Biol Interact 2005; 155: 97–110
  • Moza PN, Hustert K, Kettrup A. Photooxidation of naphthalene and phenanthrene in hexane as an oil film on water. Chemosphere 1999; 39: 569–574
  • Deyashiki Y, Ohshima K, Nakanishi M, Sato K, Matsuura K, Hara A. Molecular cloning and characterization of mouse estradiol 17β-dehydrogenase (A-specific), a member of the aldoketoreductase family. J Biol Chem 1995; 270: 10461–10467
  • Matsunaga T, Shintani S, Hara A. Multiplicity of mammalian reductases for xenobiotic carbonyl compounds. Drug Metab Pharmacokinet 2006; 21: 1–18
  • Vergnes L, Phan J, Stolz A, Reue K. A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13. J Lipid Res 2003; 44: 503–511

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