784
Views
13
CrossRef citations to date
0
Altmetric
Research Article

Photometric microplate assay for estimation of the efficacy of paraoxon-inhibited acetylcholinesterase reactivation

, &
Pages 781-784 | Received 20 Sep 2007, Accepted 30 Oct 2007, Published online: 20 Oct 2008

References

  • J Wiesner, Z Kriz, K Kuca, D Jun, and J Koca. (2007). Acetylcholinesterases – the structural similarities and differences. J Enz Inhib Med Chem 22:417–424.
  • MP Mattozzi, SK Tehara, T Hong, and JD Keasling. (2006). Mineralization of paraoxon and its use as a sole C and P source by a rationally designed catabolic pathway in Pseudomonas putida. Appl Environ Microb 72:6699–6706.
  • J Bajgar. (2004). Organophosphates/nerve agent poisoning: Mechanism of action, diagnosis, prophylaxis, and treatment. Adv Clin Chem 38:151–216.
  • K Kuca, D Jun, and K Musilek. (2006). Structural requirements of acetylcholinesterase reactivators. Mini Rev Med Chem 6:269–277.
  • J Bajgar, J Fusek, K Kuca, L Bartosova, and D Jun. (2007). Treatment of organophosphate intoxication using cholinesterase reactivators: Facts and fiction. Mini Rev Med Chem 7:461–466.
  • K Kuca, D Jun, and J Bajgar. (2007). Currently used cholinesterase reactivators against nerve agent intoxication: Comparison of their effectivity in vitro. Drug Chem Toxicol 30:31–40.
  • S Vesela, V Ondruska, K Kuca, and J Patocka. (2006). Test with Daphnia magna: A new approach to prescreen toxicity of newly synthesized acetylcholinesterase reactivotors. J Enz Inhib Med Chem 21:427–432.
  • M Pohanka, D Jun, and K Kuca. (2007). Amperometric biosensor for evaluation of competitive cholinesterase inhibition by the reactivator HI-6. Anal Lett. 40:2351–2359.
  • M Hrabinova, K Musilek, D Jun, and K Kuca. (2006). New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin. J Enz Inhib Med Chem 21:512–519.
  • K Kuca, and J Kassa. (2003). A comparison of the ability of a new bispyridinium oxime-1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane dibromide and currently used oximes to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods. J Enz Inhib Med Chem 18:529–535.
  • J Kassa, D Jun, and K Kuca. (2007). A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun- poisoned rats. J Enz Inhib Med Chem 22:297–300.
  • K Musilek, O Holas, K Kuca, D Jun, V Dohnal, and M Dolezal. (2007). Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. J Enz Inhib Med Chem 22:425–432.
  • K Kuca, J Cabal, D Jun, J Bajgar, and M Hrabinova. (2006). Potency of new structurally different oximes to reactivate cyclosarin-inhibited human brain acetylcholinesterases. J Enz Inhib Med Chem 21:663–666.
  • K Musilek, K Kuca, D Jun, V Dohnal, and M Dolezal. (2005). Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase. J Enz Inhib Med Chem 20:409–415.
  • J Picha, K Kuca, M Kivala, M Kohout, J Cabal, and F Liska. (2005). A new group of monoquaternary reactivators of acetylcholinesterase inhibited by nerve agents. J Enz Inhib Med Chem 20:233–237.
  • K Kuca, and J Patocka. (2004). Reactivation of cyclosarin-inhibited rat brain acetylcholinesterase by pyridinium-oximes. J Enz Inhib Med Chem 19:39–43.
  • K Kuca, J Cabal, and J Kassa. (2005). In vitro reactivation of sarin-inhibited brain acetylcholinesterase from diferent species by various oximes. J Enz Inhib Med Chem 20:227–232.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.