1,973
Views
45
CrossRef citations to date
0
Altmetric
Research Article

Evaluation of anti-inflammatory and antioxidant activities of Copper (II) Schiff mono-base and Copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole

, &
Pages 1011-1017 | Received 10 Sep 2007, Accepted 14 Nov 2007, Published online: 20 Oct 2008

References

  • K Nakajima, Y Ando, H Mano, and M Kojima. (1998). Photosubstitution reactivity, crystal structures, and electrochemistry of ruthenium(II) (III) complexes containing tetradentate (O2N2, S2N2, and P2N2) Schiff base ligands. Inorg Chim Acta 274 (2):184–191.
  • A Golcu, M Tumer, H Demirelli, and RA Wheatley. (2005). Cd(II) and Cu(II) complexes of polydentate Schiff base ligands: Synthesis, characterization, properties and biological activity. Inorg Chim Acta 358 (6):1785–1797.
  • ATh Chaviara, PC Christidis, A Papageorgiou, E Chrysogelou, DJ Hadjipavlou-Litina, and CA Bolos. (2005). In vivo anticancer, anti-inflammatory, and toxicity studies of mixed-ligand Cu(II) complexes of dien and its Schiff dibases with heterocyclic aldehydes and 2-amino-2-thiazoline. Crystal structure of [Cu(dien)(Br)(2a-2tzn)](Br)(H2O). J Inorg Biochem 99 (11):2102–2109.
  • ME Hossain, MN Alam, J Begum, AM Akbar, M Nazimuddin, FE Smith, and RC Hynes. (1996). The preparation, characterization, crystal structure and biological activities of some copper(II) complexes of the 2-benzoylpyridine Schiff bases of S-methyl- and S-benzyldithiocarbazate. Inorg Chim Acta 249 (2):207–213.
  • EM Hodnett, and PD Mooney. (1970). Antitumor activities of some Schiff bases. J Med Chem 13 (4): 786–786
  • ATh Chaviara, PJ Cox, KH Repana, RM Papi, KT Papazisis, D Zambouli, AH Kortsaris, DA Kyriakidis, and CA Bolos. (2004). Copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole: Synthesis, characterization, antiproliferative and antibacterial studies. Crystal structure of CudienOOCl2. J Inorg Biochem 98 (8):1271–1283.
  • ATh Chaviara, PJ Cox, KH Repana, AA Pantazaki, KT Papazisis, AH Kortsaris, DA Kyriakidis, GSt Nikolov, and CA Bolos. (2005). The unexpected formation of biologically active Cu(II) Schiff mono-base complexes with 2-thiophene-carboxaldehyde and dipropylenetriamine: Crystal and molecular structure of CudptaSCl2. J Inorg Biochem 99 (2):467–476.
  • DB Marks, AD Marks, CM Smith. Basic medical biochemistry: A clinical approach. Philadelphia: Lippincott Williams & Wilkins; (1996).
  • CT Dillon, TW Hambley, BJ Kennedy, PA Lay, and JE Weder. (2004). Copper and zinc complexes as antiinflammatory drugs. Met Ions Biol Syst 41:253–277.
  • RK Parashar, RC Sharma, and G Mohan. (1989). Biological activity of some Schiff bases and their metal complexes. Biol Trace Elem Res 23:145–150.
  • S Okuyama, S Hashimoto, H Aihara, WM Willingham, and JR Sorenson. (1987). Copper complexes of non-steroidal antiinflammatory agents: Analgesic activity and possible opioid receptor activation. Agents Actions 21:130–144.
  • DH Brown, WE Smith, JW Teape, and AJ Lewis. (1980). Antiinflammatory effects of some copper complexes. J Med Chem 23 (7):729–734.
  • MH Shih, and FY Ke. (2004). Syntheses and evaluation of antioxidant activity of sydnonyl substituted thiazolidinone and thiazoline derivatives. Bioorg Med Chem 12 (17):4633–4643.
  • K Singh, MS Barwa, and P Tyagi. (2005). Synthesis, characterization and biological studies of Co(II), Ni(II), Cu(II) and Zn(II) complexes with bidentate Schiff bases derived by heterocyclic ketone. Eur J Med Chem 41 (1):147–153.
  • M Pellei, GG Lobbia, C Santini, R Spagna, M Camalli, D Fedeli, and G Falcioni. (2004). Synthesis, characterization and antioxidant activity of new copper(I) complexes of scorpionate and water soluble phosphane ligands. J Chem Soc Dalton Trans 17:2822–2828.
  • J Vanco, O Svajlenova, E Ramanska, J Muselik, and JJ Valentova. (2004). Antiradical activity of different copper(II) Schiff base complexes and their effect on alloxan-induced diabetes. J Trace Elem Med Biol 18 (2):155–161.
  • C Santini, M Pellei, GG Lobbia, D Fedeli, and G Falcioni. (2003). Synthesis and characterization of new copper(I) complexes containing 4-(diphenylphosphane)benzoic acid and “scorpionate” ligands with “in vitro” superoxide scavenging activity. J Inorg Biochem 94 (4):348–354.
  • M Gonsalez-Alvarez, G Alzuet, J Borras, LC Agudo, JM Montejo-Bernardo, and S Garcia-Granda. (2003). J Biol Inorg Chem 8:112–120.
  • G Kornis. InAR Katritzky. editor>. 1, 3, 4-Thiadiazoles in Comprehensive Heterocyclic Chemistry., vol. 6 New York: Part 4B Pergamon Press; (1984). p545–578.
  • P Comba. (1993). The relation between ligand structures, coordination stereochemistry, and electronic and thermodynamic properties. Coord Chem Rev 123 (1-2):1–48.
  • TL Brown, and KJ Lee. (1993). Ligand steric properties. Coord Chem Rev 128 (1-2):89–116.
  • CW Holzapfel, and GR Pettit. (1985). Antineoplastic agents. Par 108. Structural biochemistry. Part 23. Synthesis of the dolastatin thiazole amino acid component (gln)Thz. J Org Chem 50 (13):2323–2327.
  • M Nakamura, T Shibata, K Nakane, T Nemoto, M Ojika, and K Yamada. (1995). Stereochemistry and total synthesis of dolastatin E. Tetrahedron Lett 36 (28):5059–5062.
  • C Boden, and G Pattenden. (1994). Total synthesis of lissoclinamide 5, a cytotoxic cyclic peptide from the tunicate Lissoclinum patella. Tetrahedron Lett 35 (44):8271–8274.
  • A Butler, and JV Walker. (1993). Marine Haloperoxidases. Chem Rev 93:1937–1944.
  • JRJ Sorenson. Inflammatory Diseases and Copper.,vol. 2 Clifton: Humana Press; (1982).
  • R Nagar, and G Mohan. (1991). Synthetic and pharmacological studies on some transition metal chelates involving N-pyrimidino benzamide-2-carboxylic acid as ligand. J Inorg Biochem 42:9–16.
  • S Oga, SF Taniguchi, R Najjar, and AR Souza. (1991). Synthesis, characterization, and biological screening of a copper flurbiprofen complex with anti-inflammatory effects. J Inorg Biochem 41 (1):45–51.
  • ZH Chohan, H Pervez, A Rauf, A Scozzafava, and CT Supuran. (2002). Antibacterial Co(II), Cu(II), Ni(II) and Zn(II) complexes of thiadiazole derived furanyl, thiophenyl and pyrrolyl Schiff bases. J Enz Inhib Med Chem 17 (2):117–122.
  • RO Day, GG Graham, KM Williams, and PM Brooks. (1988). Variability in response to NSAIDs. Fact or fiction?. Drugs 36 (6):643–651.
  • GA Ellis, and DR Blake. (1993). Why are non-steroidal anti-inflammatory drugs so variable in their efficacy? A description of ion trapping. Ann Rheum Dis 52 (3):241–243.
  • E Pontiki, D Hadjipavlou-Litina, ATh Chaviara, and CA Bolos. (2006). Evaluation of anti-inflammatory and antioxidant activities of mixed-ligand Cu(II) complexes of dien and its Schiff dibases with heterocyclic aldehydes and 2-amino-2-thiazoline. Bioorg Med Chem Lett 16 (8):2234–2237.
  • D Panagoulis, E Pontiki, E Skeva, C Raptopoulou, S Girousi, D Hadjipavlou-Litina, and C Dendrinou-Samara. (2007). Synthesis and pharmacochemical study of new Cu(II) complexes with thiophen-2-yl saturated and α,β-unsaturated substituted carboxylic acids. J Inorg Biochem 101 (4):623–634.
  • Chaviara ATh. Thesis, Aristotles University,2006, Thessaloniki.
  • Pontiki E, Hadjipavlou-Litina D. Lipoxygenase inhibitors: A comparative QSAR study review and evaluation of new QSARs, Med Res Rev, Epub ahead of print – 26 December 2006 in press.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.