88
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Exposure to emissions generated by 3-dimensional printing with polycarbonate: effects on peripheral vascular function, cardiac vascular morphology and expression of markers of oxidative stress in male rat cardiac tissue

, , , , , , , , , , , & show all

References

  • Abraham, A., and P. Chakraborty. 2019. “A Review on Sources and Health Impacts of Bisphenol A.” Reviews on Environmental Health 35 (2): 201–210. https://doi.org/10.1515/reveh-2019-0034.
  • Bailey, S. R., S. Mitra, S. Flavahan, and N. A. Flavahan. 2005. “Reactive Oxygen Species from Smooth Muscle Mitochondria Initiate Cold-Induced Constriction of Cutaneous Arteries.” American Journal of Physiology Heart & Circulatory Physiology 289 (1): H243–H250. https://doi.org/10.1152/ajpheart.01305.2004.
  • Barbato, E. 2009. “Role of Adrenergic Receptors in Human Coronary Vasomotion.” Heart 95 (7): 603–608. https://doi.org/10.1136/hrt.2008.150888.
  • Cimmino, I., F. Fiory, G. Perruolo, C. Miele, F. Beguinot, P. Formisano, and F. Oriente. 2020. “Potential Mechanisms of Bisphenol a (BPA) Contributing to Human Disease.” International Journal of Molecular Sciences 21 (16): 5761. https://doi.org/10.3390/ijms21165761.
  • Curry, B. D., S. R. Govindaraju, J. L. W. Bain, L. L. Zhang, J.-G. Yan, H. S. Matloub, and D. A. Riley. 2005. “Evidence for Frequency-Dependent Arterial Damage in Vibrated Rat Tails.” The Anatomical Record Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology 284A (2): 511–521. https://doi.org/10.1002/ar.a.20186.
  • Dias, P., V. Tvrdý, W. Jirkovský, M. Sollner Dolenc, L. Peterlin Mašič, and P. Mladěnka. 2022. “The Effects of Bisphenols on the Cardiovascular System.” Critical Reviews in Toxicology 52 (1): 66–87. https://doi.org/10.1080/10408444.2022.2046690.
  • Drożdż, D., M. Drożdż, and M. Wójcik. 2023. “Endothelial Dysfunction As a Factor Leading to Arterial Hypertensions.” Pediatric Nephrology 38 (9): 2973–2985. https://doi.org/10.1007/s00467-022-05802-z.
  • Eid, A. H., K. Maiti, S. Mitra, M. A. Chotani, S. Flavahan, S. R. Bailey, C. S. Thompson-Torgerson, and N. A. Flavahan. 2007. “Estrogen Increases Smooth Muscle Expression of α 2C -Adrenoceptors and Cold-Induced Constriction of Cutaneous Arteries.” American Journal of Physiology Heart & Circulatory Physiology 293 (3): H1955–H1961. https://doi.org/10.1152/ajpheart.00306.2007.
  • Farcas, M. T., W. McKinney, W. K. Mandler, A. K. Knepp, L. Batelli, S. A. Friend, A. B. Stefaniak, et al. 2024. “2024Pulmonary Evaluation of Whole-Body Exposure of Polycarbonate (PC) Filament 3D Printer Emissions in Rats.” Journal of Toxicology and Environmental Health Part A 87 (8): 325–341. https://doi.org/10.1080/15287394.2024.2311170.
  • Farcas, M. T., W. McKinney, C. Qic, W. K. Mandler, S. A. Friend, A. Stefaniak, M. Jackson, et al. 2020. “Pulmonary and Systemic Toxicity in Rats Following Inhalation Exposure of 3-D Printer Emissions from Acrylonitrile Butadiene Styrene (ABS) Filament.” Inhalation Toxicology 32 (11–12): 403–418. https://doi.org/10.1080/08958378.2020.1834034.
  • Farcas, M. T., A. B. Stefaniak, A. K. Knepp, W. K. Mandler, M. Kashon, S. R. Jackson, T. A. Stueckle, et al. 2019. “Acrylonitrile Butadiene Styrene (ABS) and Polycarbonate (PC) Filaments Three-Dimensional (3-D) Printer Emissions-Induced Cell Toxicity.” Toxicology Letters 317:1–12. https://doi.org/10.1016/j.toxlet.2019.09.013.
  • Gradinaru, D., C. Borsa, C. Ionescu, and G. I. Prada. 2015. “Oxidized LDL and NO Synthesis—Biomarkers of Endothelial Dysfunction and Ageing.” Mechanisms of Ageing and Development 151:101–113. https://doi.org/10.1016/j.mad.2015.03.003.
  • Hubbs, A. F., R. R. Mercer, S. A. Benkovic, J. Harkema, K. Sriram, D. Schwegler-Berry, M. P. Goravanahally, T. R. Nurkiewicz, V. Castranova, and L. M. Sargent. 2011. “Nanotoxicology—A Pathologist’s Perspective.” Toxicologic Pathology 39 (2): 301–324. https://doi.org/10.1177/0192623310390705.
  • Hughes, J. M., O. Wirth, K. Krajnak, R. Miller, S. Flavahan, D. E. Berkowitz, D. Welcome, and N. A. Flavahan. 2009. “Increased Oxidant Activity Mediates Vascular Dysfunction in Vibration Injury.” Journal of Pharmacology and Experimental Therapeutics 328 (1): 223–230. https://doi.org/10.1124/jpet.108.144618.
  • Huxley, V. H. 2007. “Sex and Cardiovascular System: The Intriguing Tale of How Women and Men Regulate Cardiovascular Function Differently.” Advances in Physiology Education 31 (1): 17–22. https://doi.org/10.1152/advan.00099.2006.
  • Johnson, D. 2013. “Nanoparticles Emitted from 3D Printers Could Pose a Risk: Emission Rates Are on Par with Other Household Devices, but the Particles May Be More Toxic.” IEEE Specturm. https://spectrum.ieee.org/nanoparticles-emitted-from-3d-printers-could-pose-a-risk.
  • Khraishah, H., B. Alahmad, R. L. Ostergard, A. AlAshqar, M. Albaghdadi, N. Vellanki, M. M. Chowdhury, et al. 2022. “Climate Change and Cardiovascular Disease: Implications for Global Health.” Nature Reviews Cardiology 19 (12): 798–812. https://doi.org/10.1038/s41569-022-00720-x.
  • Kim, J.-J., S. Kumar, V. Kumar, Y.-M. Lee, Y.-S. Kim, and V. Kumar. 2020. “Bisphenols As a Legacy Pollutant, and Their Effects on Organ Vlulnerability.” International Journal of Environmental Research and Public Health 17 (1): 112. https://doi.org/10.3390/ijerph17010112.
  • Kim, E. J., D. Lee, B. C. Chung, H. Pyo, and J. Lee. 2014. “Association Between Urinary Levels of Bisphenol-A and Estrogen Metabolism in Korean Adults.” Science of the Total Environment 470-471:1401–1407. https://doi.org/10.1016/j.scitotenv.2013.07.040.
  • Kotsonis, P., A. Frey, L. G. Fröhlich, H. Hofmann, A. Reif, D. A. Wink, M. Feelisch, and H. H. Schmidt. 1999. “Autoinhibition of Neuronal Nitric Oxide Synthase: Distinct Effects of Reactive Nitrogen and Oxygen Species on Enzyme Activity.” The Biochemical Journal 340 (3): 745–752. https://doi.org/10.1042/bj3400745.
  • Krajnak, K., R. G. Dong, S. Flavahan, D. Welcome, and N. A. Flavahan. 2006. “Acute Vibration Increases α 2C -Adrenergic Smooth Muscle Constriction and Alters Thermosensitivity of Cutaneous Arteries.” Journal of Applied Physiology 100 (4): 1230–1237. https://doi.org/10.1152/japplphysiol.00761.2005.
  • Krajnak, K., M. Farcas, J. Richardson, M. A. Hammer, S. Waugh, W. McKinney, M. Jackson, D. Matheson, T. Thomas, and Y. Qian. 2023. “Inhalation of Polycarbonate Emissions Generated During 3D Printing Processes Affects Neuroendocrine Function in Male Rats.” Journal of Toxicology and Environmental Health Part A 86 (16): 575–596. https://doi.org/10.1080/15287394.2023.2226198.
  • Krajnak, K., H. Kan, K. A. Russ, W. McKinney, S. Waugh, W. Zheng, M. L. Kashon, C. Johnson, J. Cumpston, and J. S. Fedan. 2020. “Biological Effects of Inhaled Hydraulic Fracturing Sand Dust. VI. Cardiovascular Effects.” Toxicology & Applied Pharmacology 406:115242. https://doi.org/10.1016/j.taap.2020.115242.
  • Krajnak, K., G. R. Miller, S. Waugh, C. Johnson, and M. L. Kashon. 2010. “Characterization of Frequency-Dependent Responses of the Sensorineural System to Repetitive Vibration.” Journal of Occupational & Environmental Medicine / American College of Occupational & Environmental Medicine 54 (8): 1010–1016. https://doi.org/10.1097/JOM.0b013e318255ba74.
  • Krajnak, K., K. A. Russ, W. McKinney, S. Waugh, W. Zheng, H. Kan, M. L. Kashon, J. Cumpston, and J. S. Fedan. 2022. “Biological effects of crude oil vapor. IV. Cardiovascular effects.” Toxicology & Applied Pharmacology 447:116071. https://doi.org/10.1016/j.taap.2022.116071.
  • Krajnak, K., K. Sriram, C. Johnson, J. R. Roberts, R. R. Mercer, G. R. Miller, O. Wirth, and J. M. Antonini. 2017. “Effects of Pulmonary Exposures to Chemically-Distinct Welding Fumes on Neuroendocrine Markers of Toxicity.” Journal of Toxicology and Environmental Health Part A 80 (5): 301–314. https://doi.org/10.1080/15287394.2017.1318324.
  • Krajnak, K., S. Waugh, C. Johnson, G. R. Miller, X. Xu, C. Warren, and R. G. Dong. 2013. “The Effects of Impact Vibration in Peripheral Blood Vessles and Nerves.” Industrial Health 51 (6): 572–580. https://doi.org/10.2486/indhealth.2012-0193.
  • Krajnak, K., S. Waugh, R. Miller, B. Baker, K. Geronilla, S. E. Alway, and R. G. Cutlip. 2006. “Acute Vibration Reduces Aβ Nerve Fiber Sensitivity and Alters Gene Expression in the Ventral Tail Nerves of Rats.” Muscle & Nerve 36 (2): 197–205. https://doi.org/10.1002/mus.20804.
  • Kuzkaya, N., N. Weissmann, D. G. Harrison, and S. Dikalov. 2003. “Interactions of Peroxynitrite, Tetrahydrobiopterin, Ascorbic Acid, and Thiols: Implications for Uncoupling Endothelial Nitric-Oxide Synthase.” Journal of Biological Chemistry 278 (25): 22546–22554. https://doi.org/10.1074/jbc.M302227200.
  • Lehmler, H., J. Liu, B. Gadogbe, and W. Bao. 2018. “Exposure to Bisphenol A, Bisphenol F, and Bisphenol S in U.S. Adults and Children: The National Health and Nutrition Examination Survey 2013–2014.” American Chemical Society Omega 3 (6): 6523–6532. https://doi.org/10.1021/acsomega.8b00824.
  • Lundberg, U., L. Wallin, G. Lindstedt, and M. Frankenhaueser. 1990. “Steroid Sex Hormones and Cardiovascular Function in Health Males and Females: A Correlational Study.” Pharmacology, Biochemistry, and Behavior 37 (2): 325–327. https://doi.org/10.1016/0091-3057(90)90342-F.
  • Mackay, H., and A. Abidzaid. 2018. “A Plurality of Molecular Targets: The Receptor Ecosytem for Bisphenol-A (BPA).” Hormones and Behavior 101:59–67. https://doi.org/10.1016/j.yhbeh.2017.11.001.
  • Ma, Y., H. Liu, J. Wu, L. Yuan, Y. Wang, X. du, R. Want, et al. 2019. “The Adverse Health Effects of Bisphenol a and Related Toxicity Mechanisms.” Environmental Research 176:108575. https://doi.org/10.1016/j.envres.2019.108575.
  • Meza-Alvarado, J. C., R. A. Page, B. Mallard, C. Bromhead, and B. R. Palmer. 2023. “VEGF- a Related SNPs: A Cardiovascular Context.” Frontiers in Cardiovascular Medicine 10. https://doi.org/10.3389/fcvm.2023.1190513.
  • NTP (National Toxicology Program). 2021. “NTP Research Report on the Consortium Linking Academic and Regulatory Insights on Bisphenol a Toxicity (CLARITY-BPA): A Compendium of Published Findings.” Research Triangle Park, North Carolina.
  • Pandey, A. K., E. K. Singhi, J. P. Arroyo, T. A. Ikizler, E. R. Gould, J. Brown, J. A. Beckman, D. G. Harris, and J. Moslehi. 2017. “Mechanisms of VEGF (Vascular Endothelial Growth Factor) Inhibitor–Associated Hypertension and Vascular Disease.” Hypertension 71 (2): e1–e8. https://doi.org/10.1161/HYPERTENSIONAHA.117.10271.
  • Phillips, S. A., F. A. Suylvester, and J. C. Frisbee. 2005. “Oxidant Stress and Constrictor Reactivity Impair Cerebral Artery Dilation in Obese Zucker Rats.” American Journal of Physiology Regulatory, Integrative and Comparative Physiology 288 (2): R522–30. https://doi.org/10.1152/ajpregu.00655.2004.
  • Roberts, J. R., S. E. Anderson, H. Kan, K. Krajnak, J. A. Thompson, A. Kenyon, W. T. Goldsmith, et al. 2014. “Evaluation of Pulmonary and Systemic Toxicity of Oil Dispersant (COREXIT EC9500A((R))) Following Acute Repeated Inhalation Exposure.” Environmental Health Insights 8 (Suppl 1): 63–74. https://doi.org/10.4137/EHI.S15262.
  • Rochester, J. A. 2013. “Bisphenol a and Human Health: A Review of the Literature.” Reproductive Toxicology (Elmsford, NY) 42:132–155. https://doi.org/10.1016/j.reprotox.2013.08.008.
  • Sanchez, P., B. Castro, S. Martinez-Rodriguez, R. Rios-Pelegrina, R. G. del Moral, J. M. Torres, and E. Ortega. 2022. “Impact of Chronic Exposure of Rats to Bisphenol a from Perinatal Period to Adulthood on Intraprostatic Levels of 5α-Reductase Isozymes, Aromatase, and Genes Implicated in Prostate Cancer Development.” Environmental Research 212 (Part A): 113142. https://doi.org/10.1016/j.envres.2022.113142.
  • Secondo, L. E., H. I. Adawi, J. Cuddehe, J. K. Hopson, A. Schumacher, L. Mendoza, C. Cartin, and N. A. Lewinskin. 2020. “Comparative Analysis of Ventilation Efficiency on Ultrafine Particle Removal in University Makerspaces.” Atmospheric Environment 224:117321. https://doi.org/10.1016/j.atmosenv.2020.117321.
  • Shivika, S., and C. Subhankar. 2017. “Microplastic Pollution, a Threat to Marine Ecosystem and Human Health: A Short Review.” Environmental Science and Pollution Research 24 (27): 21530–21547. https://doi.org/10.1007/s11356-017-9910-8.
  • Stefaniak, A. B., S. du Preez, and J. L. du Plessis. 2021. “Additive Manufacturing for Occupational Hygiene: A Comprehensive Review of Processes, Emissions and Exposures.” Journal of Toxicology and Environmental Health, Part B 24 (5): 173–222. https://doi.org/10.1080/10937404.2021.1936319.
  • Stefaniak, A. B., R. F. LeBouf, M. G. Duling, J. Yi, A. B. Abukabda, C. R. McBride, and T. R. Nurkiewicz. 2017. “Inhalation Exposure to Three-Dimensional Printer Emissions Stimulates Acute Hypertension and Microvascular Dysfunction.” Toxicology and Applied Pharmacology 335:1–5. https://doi.org/10.1016/j.taap.2017.09.016.
  • Stephens, B., P. Azimi, Z. E. Orch, and T. Ramos. 2013. “Ultrafine paticle emissions from destop 3D printers.” Atmospheric Environment 79:334–339. https://doi.org/10.1016/j.atmosenv.2013.06.050.
  • Tarskikh, M. M., L. G. Klimatskaya, and S. I. Kolesnikov. 2013. “Pathogenesis of Neurotoxicity of Acrylates Acrylonitrile and Acrylamide: From Cell to Organism.” Bulletin of Experimental Biology and Medicine 155 (4): 451–453. https://doi.org/10.1007/s10517-013-2175-4.
  • Väisänen, A., L. Alonen, S. Ylönen, and M. Hyttinen. 2022. “Organic Compound and Particle Emissions of Additive Manufacturing with Photopolymer Resins and Chemical Outgassing of Manufactured Resin Products.” Journal of Toxicology and Environmental Health Part A 85 (5): 198–216. https://doi.org/10.1080/15287394.2021.1998814.
  • Xia, Y., V. L. Dawson, T. M. Dawson, S. H. Snyder, and J. L. Zweier. 1996. “Nitric Oxide Synthase Generates Superoxide and Nitric Oxide in Arginine-Depleted Cells Leading to Peroxynitrite-Mediated Cellular Injury.” Proceedings of the National Academy of Sciences 93 (13): 6770–6774. https://doi.org/10.1073/pnas.93.13.6770.
  • Yi, J., R. F. LeBouf, M. G. Duling, T. Nurkiewicz, B. T. Chen, D. Schwegler-Berry, M. A. Virji, and A. B. Stefaniak. 2016. “Emission of Particulate Matter from a Desktop Three-Dimensional (3D) Printer.” Journal of Toxicology and Environmental Health Part A 79 (11): 453–465. https://doi.org/10.1080/15287394.2016.1166467.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.