172
Views
0
CrossRef citations to date
0
Altmetric
Research Article

The increase in c-fos expression in epileptic seizures is inhibited by magnetic field application, but not KCa1.1 channel expression

, , , , , , & show all
Pages 81-97 | Received 11 Apr 2023, Accepted 15 Jul 2023, Published online: 20 Aug 2023

References

  • Akdag, M. Z., S. Dasdag, D. U. Cakir, B. Yokus, G. Kizil, and M. Kizil. 2013. Do 100 and 500 µT ELF magnetic fields alter beta amyloid protein, protein carbonyl and malondialdehyde in brain? Electromagn Biol. Med. 32 :363–72. doi:10.3109/15368378.2012.721848.
  • Akdag, M. Z., S. Dasdag, E. Ulukaya, A. K. Uzunlar, M. A. Kurt, and A. Taskin. 2010. Effects of extremely low-frequency magnetic field on caspase activities and oxidative stress values in rat brain. Biol. Trace. Elem. Res. 138 :238–49. doi:10.1007/s12011-010-8615-3.
  • Akyuz, E., Z. Doganyigit, Y. N. Paudel, B. Koklu, E. Kaymak, C. Villa, A. Arulsamy, M. F. Shaikh, and O. Devinsky. 2021. Immunoreactivity of muscarinic acetylcholine m2 and serotonin 5-ht2b receptors, norepinephrine transporter and kir channels in a model of epilepsy. Life (Basel) 11 :276. doi:10.3390/life11040276.
  • Arslan, D., A. Ekinci, A. Arici, E. Bozdemir, E. Akil, and H. H. Ozdemir. 2017. Effects of ecballium elaterium on brain in a rat model of sepsis-associated encephalopathy. Libyan J. Med. 12 :1369834. doi:10.1080/19932820.2017.1369834.
  • Burger, T., M. Lucova, R. E. Moritz, H. H. Oelschlager, R. Druga, H. Burda, W. Wiltschko, R. Wiltschko, and P. Nemec. 2010. Changing and shielded magnetic fields suppress c-fos expression in the navigation circuit: Input from the magnetosensory system contributes to the internal representation of space in a subterranean rodent. J. R. Soc. Interface 7 :1275–92. doi:10.1098/rsif.2009.0551.
  • Canseven, A. G., Z. A. Keskil, S. Keskil, and N. Seyhan. 2007. Pentylenetetrazol-induced seizures are not altered by pre- or post-drug exposure to a 50 hz magnetic field. Int. J. Radiat. Biol. 83 :231–35. doi:10.1080/09553000701206676.
  • Choung, J. S., J. M. Kim, M. H. Ko, D. S. Cho, and M. Kim. 2021. Therapeutic efficacy of repetitive transcranial magnetic stimulation in an animal model of alzheimer’s disease. Sci. Rep. 11 :437. doi:10.1038/s41598-020-80147-x.
  • Cogan, S. F. 2008. Neural stimulation and recording electrodes. Annu. Rev. Biomed. Eng. 10 :275–309. doi:10.1146/annurev.bioeng.10.061807.160518.
  • Dasdag, S., M. Z. Akdag, H. Er, V. Akpolat, and E. Deveci. 2023. The interstitial space between cells in left and right lobes of brains exposed 900, 1800 and 2100 MHz radiofrequency radiation. Biotechnol. Biotec. Eq. 37 :180–87. doi:10.1080/13102818.2023.2170828.
  • Duret, G., S. Polali, E. D. Anderson, A. M. Bell, C. N. Tzouanas, B. W. Avants, and J. T. J. B. J. Robinson. 2019. Magnetic entropy as a proposed gating mechanism for magnetogenetic ion channels. Biophys. J. 116 :454–68. doi:10.1016/j.bpj.2019.01.003.
  • Duy, P. Q., M. A. Berberoglu, C. E. Beattie, and C. W. Hall. 2017. Cellular responses to recurrent pentylenetetrazole-induced seizures in the adult zebrafish brain. Neuroscience 349:118–27. doi:10.1016/j.neuroscience.2017.02.032.
  • Erdtmann-Vourliotis, M., U. Riechert, P. Mayer, G. Grecksch, and V. J. B. R. Höllt. 1998. Pentylenetetrazole (ptz)-induced c-fos expression in the hippocampus of kindled rats is suppressed by concomitant treatment with naloxone. Brain Res. 792 :299–308. doi:10.1016/S0006-8993(98)00159-0.
  • Fisicaro, F., G. Lanza, A. A. Grasso, G. Pennisi, R. Bella, W. Paulus, and M. Pennisi. 2019. Repetitive transcranial magnetic stimulation in stroke rehabilitation: Review of the current evidence and pitfalls. Ther Adv Neurol Disord 12:1756286419878317. doi:10.1177/1756286419878317.
  • Gersne R., S. C. Dhamne, A. Zangen, A. Pascual-Leone, and A. Rotenberg. 2016. Bursts of high-frequency repetitive transcranial magnetic stimulation (rTMS), together with lorazepam, suppress seizures in a rat kainate status epilepticus model. Epilepsy Behav 62:136–39. doi:10.1016/j.yebeh.2016.05.021.
  • Graff-Guerrero, A., J. Gonzales-Olvera, M. Ruiz-Garcia, U. Avila-Ordonez, V. Vaugier, and J. C. Garcia-Reyna. 2004. rTMS reduces focal brain hyperperfusion in two patients with epc. Acta Neurol. Scand. 109 :290–96. doi:10.1046/j.1600-0404.2003.00222.x.
  • Jung, S. H., J. E. Shin, Y. S. Jeong, and H. I. Shin. 2008. Changes in motor cortical excitability induced by high-frequency repetitive transcranial magnetic stimulation of different stimulation durations. Clin Neurophysiol 119 :71–79. doi:10.1016/j.clinph.2007.09.124.
  • Kimiskidis, V. K., A. Valentin, and R. Kalviainen. 2014. Transcranial magnetic stimulation for the diagnosis and treatment of epilepsy. Curr. Opin. Neurol. 27 :236–41. doi:10.1097/WCO.0000000000000071.
  • Liu, J., J. Li, P. Tian, B. Guli, G. Weng, L. Li, and Q. Chieng. 2019. H2S attenuates sepsis-induced cardiac dysfunction via a PI3K/Akt-dependent mechanism. Exp. Ther. Med. 17 :4064–72. doi:10.3892/etm.2019.7440.
  • Luo, Y., J. Yang, H. Wang, Z. Gan, and D. Ran. 2019. Cellular mechanism underlying RTMs treatment for the neural plasticity of nervous system in drosophila brain. Int. J. Mol. Sci. 20 :4625. doi:10.3390/ijms20184625.
  • Malhi, S. M., H. Jawed, F. Hanif, N. Ashraf, F. Zubair, B. S. Siddiqui, S. Begum, N. Kabir, and S. U. Simjee. 2014. Modulation of c-fos and BDNF protein expression in pentylenetetrazole-kindled mice following the treatment with novel antiepileptic compound hhl-6. Biomed. Res. Int. 2014:876712. doi:10.1155/2014/876712.
  • Mohamed, H. K., S. A. J. A. Eltony, and C. Biology. 2020. Effect of acute pentylenetetrazol injection induced epileptic seizures on rat dentate gyrus at different postnatal ages. 53 :84. doi:10.5115/acb.19.083.
  • N’gouemo, P. 2011. Targeting bk (big potassium) channels in epilepsy. Expert Opin. Ther. Targets 15 :1283–95. doi:10.1517/14728222.2011.620607.
  • N’gouemo, P. 2014. Bkca channel dysfunction in neurological diseases. Front Physiol 5:373. doi:10.3389/fphys.2014.00373.
  • Okan, A., Z. Doğanyiğit, E. Eroğlu, E. Akyüz, and N. Demir. 2021. Immunoreactive definition of TNF- α$\alpha $, HIF-1 α$\alpha $, Hir6.2, Kir3.1 and M2 muscarinic receptor for cardiac and pancreatic tissues in a mouse model for type 1 diabetes. Life Sci. 284:119886. doi:10.1016/j.lfs.2021.119886.
  • Okano, H., A. Fujimura, T. Kondo, I. Laakso, H. Ishiwatari, K. Watanuki, and Y. Fukumoto. 2021. A 50 hz magnetic field affects hemodynamics, ecg and vascular endothelial function in healthy adults: A pilot randomized controlled trial. PLoS One 16 :e0255242. doi:10.1371/journal.pone.0255242.
  • Patel, D. C., B. P. Tewari, L. Chaunsali, and H. Sontheimer. 2019. Neuron-glia interactions in the pathophysiology of epilepsy. Nat. Rev. Neurosci. 20 :282–97. doi:10.1038/s41583-019-0126-4.
  • Pell, G. S., Y. Roth, and A. Zangen. 2011. Modulation of cortical excitability induced by repetitive transcranial magnetic stimulation: Influence of timing and geometrical parameters and underlying mechanisms. Prog. Neurobiol. 93 :59–98. doi:10.1016/j.pneurobio.2010.10.003.
  • Polikov, V. S., P. A. Tresco, and W. M. Reichert. 2005. Response of brain tissue to chronically implanted neural electrodes. J. Neurosci. Methods 148 :1–18. doi:10.1016/j.jneumeth.2005.08.015.
  • Racine, R. J. 1972. Modification of seizure activity by electrical stimulation. Ii. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32 :281–94. doi:10.1016/0013-4694(72)90177-0.
  • Rivadulla, C., J. Aguilar, M. Coletti, J. Aguila, S. Prieto, and J. Cudeiro. 2018. Static magnetic fields reduce epileptiform activity in anesthetized rat and monkey. Sci Rep 8 :15985. doi:10.1038/s41598-018-33808-x.
  • Starnes, K., K. Miller, L. Wong-Kisiel, and B. N. Lundstrom. 2019. A review of neurostimulation for epilepsy in pediatrics. Brain Sci 9 :283. doi:10.3390/brainsci9100283.
  • Tambe, R., P. Jain, S. Patil, P. Ghumatkar, and S. Sathaye. 2016. Antiepileptogenic effects of borneol in pentylenetetrazole-induced kindling in mice. Naunyn Schmiedebergs Arch. Pharmacol. 389 :467–75. doi:10.1007/s00210-016-1220-z.
  • Ye, H., and S. Kaszuba. 2019. Neuromodulation with electromagnetic stimulation for seizure suppression: From electrode to magnetic coil. IBRO Rep. 7:26–33. doi:10.1016/j.ibror.2019.06.001.
  • Yitzhaki, S., A. Shainberg, M. Shaked, Z. Schuss, and D. J. T. O. O. J. Fixler. 2011. Weak magnetic field at 16 hz affects cardiac myocyte ca2+ transients and reduces cells damage caused by hypoxia. Int. J. Opt. 5 :33–39. doi:10.2174/1874328501105010033.
  • Yokus, B., M. Z. Akdag, S. Dasdag, D. U. Cakir, and M. Kizil. 2008. Extremely low frequency magnetic fields cause oxidative DNA damage in rats. Int. J. Radiat. Biol. 84 :789–95. doi:10.1080/09553000802348203.
  • Yuen, A. W. C., M. R. Keezer, and J. W. J. E. Sander. 2018. Epilepsy is a neurological and a systemic disorder. Epilepsy Behav. 78:57–61. Behavior. doi:10.1016/j.yebeh.2017.10.010.
  • Zhang, Y., L. Li, X. Liu, L. Ding, X. Wu, J. Wang, M. He, H. Hou, G. Ruan, and J. J. F. I. P. H. Lai. 2020. Examination of the effect of a 50-hz electromagnetic field at 500 μt on parameters related with the cardiovascular system in rats. Front. Public Health 8:87. doi:10.3389/fpubh.2020.00087.
  • Zheng, Y., J. R. Dou, Y. Gao, L. Dong, and G. Li. 2017. Effects of 15 hz square wave magnetic fields on the voltage-gated sodium and potassium channels in prefrontal cortex pyramidal neurons. Int. J. Radiat. Biol. 93 :449–55. doi:10.1080/09553002.2016.1259671.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.